Asymmetric synthesis of antimitotic combretadioxolane with potent antitumor activity against multi-drug resistant cells

Bioorganic and Medicinal Chemistry Letters

Volumn 8, Issue 15, 1998, Pages 1997-2000

  Shirai, Ryuichi ^a   Takayama, Hisae ^a   Nishikawa, Asuka ^a   Koiso, Yukiko ^a   Hashimoto, Yuichi ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMITOTIC AGENT; ANTINEOPLASTIC AGENT; COLCHICINE; COMBRETADIOXOLANE; COMBRETASTATIN A4; DRUG DERIVATIVE; TUBULIN; UNCLASSIFIED DRUG; VINCRISTINE;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL STRAIN; CHIRALITY; DRUG CYTOTOXICITY; DRUG SYNTHESIS; ENANTIOMER; HUMAN; HUMAN CELL; LEUKEMIA P 388; MICROTUBULE; MULTIDRUG RESISTANCE; NONHUMAN; POLYMERIZATION; RAT; TUMOR CELL CULTURE;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL DIVISION; DIOXOLANES; DRUG RESISTANCE, MULTIPLE; PC12 CELLS; RATS;

EID: 0032483059     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(98)00344-8     Document Type: Article

References (19)

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