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Volumn 63, Issue 1, 2004, Pages 65-71

Alcohol and cancer: Genetic and nutritional aspects

Author keywords

Acetaldehyde; Alcohol nutrient interactions; Cancer; Chronic alcohol consumption; Cytochrome P450 2E1

Indexed keywords

ACETALDEHYDE; ALCOHOL; ALCOHOL DEHYDROGENASE; BETAINE; CHOLINE; CYTOCHROME P450 2E1; FOLIC ACID; METHIONINE; RETINOIC ACID; RIBOFLAVIN; S ADENOSYLMETHIONINE; ZINC;

EID: 11144358027     PISSN: 00296651     EISSN: None     Source Type: Journal    
DOI: 10.1079/PNS2003323     Document Type: Conference Paper
Times cited : (92)

References (78)
  • 1
    • 0001808451 scopus 로고    scopus 로고
    • Free radicals and ethanol toxicity
    • [VR Preedy and RR Watson, editors]. Boca Raton, FL: CRC Press
    • Albano E & Clot P (1996) Free radicals and ethanol toxicity. In Alcohol and the Gastrointestinal Tract, pp. 57-68 [VR Preedy and RR Watson, editors]. Boca Raton, FL: CRC Press.
    • (1996) Alcohol and the Gastrointestinal Tract , pp. 57-68
    • Albano, E.1    Clot, P.2
  • 4
    • 17544378681 scopus 로고    scopus 로고
    • Genetic polymorphism of alcohol dehydrogenase in Europeans: The ADH2*2 allele decreases the risk for alcoholism and is associated with ADH3*1
    • Borras E, Coutelle C, Rosell A, Fernandez-Muixi F, Broch M, Crosas B, et al. (2000) Genetic polymorphism of alcohol dehydrogenase in Europeans: the ADH2*2 allele decreases the risk for alcoholism and is associated with ADH3*1. Hepatology 31, 984-989.
    • (2000) Hepatology , vol.31 , pp. 984-989
    • Borras, E.1    Coutelle, C.2    Rosell, A.3    Fernandez-Muixi, F.4    Broch, M.5    Crosas, B.6
  • 6
    • 0032729779 scopus 로고    scopus 로고
    • Chronic alcohol consumption induces genomic but not p53-specific DNA hypomethylation in rat colon
    • Choi SW, Stickel F, Baik HW, Kim YI, Seitz HK & Mason JB (1999) Chronic alcohol consumption induces genomic but not p53-specific DNA hypomethylation in rat colon. Journal of Nutrition 129, 1945-1950.
    • (1999) Journal of Nutrition , vol.129 , pp. 1945-1950
    • Choi, S.W.1    Stickel, F.2    Baik, H.W.3    Kim, Y.I.4    Seitz, H.K.5    Mason, J.B.6
  • 7
    • 0037186169 scopus 로고    scopus 로고
    • Retinoic acid inhibits hepatic Jun N-terminal kinase-dependent signaling pathway in ethanol-fed rats
    • Chung J, Chavez PR, Russell RM & Wang XD (2002) Retinoic acid inhibits hepatic Jun N-terminal kinase-dependent signaling pathway in ethanol-fed rats. Oncogene 21, 1539-1547.
    • (2002) Oncogene , vol.21 , pp. 1539-1547
    • Chung, J.1    Chavez, P.R.2    Russell, R.M.3    Wang, X.D.4
  • 8
    • 0034908387 scopus 로고    scopus 로고
    • Restoration of retinoic acid concentration suppresses ethanol-enhanced c-Jun expression and hepatocyte proliferation in rat liver
    • Chung J, Liu C, Smith DE, Seitz HK, Russell RM & Wang XD (2001) Restoration of retinoic acid concentration suppresses ethanol-enhanced c-Jun expression and hepatocyte proliferation in rat liver. Carcinogenesis 22, 1213-1219.
    • (2001) Carcinogenesis , vol.22 , pp. 1213-1219
    • Chung, J.1    Liu, C.2    Smith, D.E.3    Seitz, H.K.4    Russell, R.M.5    Wang, X.D.6
  • 9
    • 0028839835 scopus 로고
    • Alterations in DNA methylation play a variety of roles in carcinogenesis
    • Counts JL & Goodman JI (1995) Alterations in DNA methylation play a variety of roles in carcinogenesis. Cell 83, 13-15.
    • (1995) Cell , vol.83 , pp. 13-15
    • Counts, J.L.1    Goodman, J.I.2
  • 12
    • 0023838697 scopus 로고
    • A mutagenicity assessment of acetaldehyde
    • Dellarco VL (1988) A mutagenicity assessment of acetaldehyde. Mutation Research 195, 1-20.
    • (1988) Mutation Research , vol.195 , pp. 1-20
    • Dellarco, V.L.1
  • 15
    • 0028978679 scopus 로고
    • Development of a 32P-postlabeling method for the analysis of adducts arising through the reaction of acetaldehyde with 2′ -deoxyguanosine-3′-monophosphate and DNA
    • Fang JL & Vaca CE (1995) Development of a 32P-postlabeling method for the analysis of adducts arising through the reaction of acetaldehyde with 2′-deoxyguanosine-3′-monophosphate and DNA. Carcinogenesis 16, 2177-2185.
    • (1995) Carcinogenesis , vol.16 , pp. 2177-2185
    • Fang, J.L.1    Vaca, C.E.2
  • 16
    • 0031416803 scopus 로고    scopus 로고
    • Detection of DNA adducts of acetaldehyde in peripheral white blood cells of alcohol abusers
    • Fang JL & Vaca CE (1997) Detection of DNA adducts of acetaldehyde in peripheral white blood cells of alcohol abusers. Carcinogenesis 18, 627-632.
    • (1997) Carcinogenesis , vol.18 , pp. 627-632
    • Fang, J.L.1    Vaca, C.E.2
  • 17
    • 0025738978 scopus 로고
    • Ethanol consumption inhibits fetal DNA methylation in mice: Implications for the fetal alcohol syndrome
    • Garro AJ, McBeth DL, Lima V & Lieber CS (1991) Ethanol consumption inhibits fetal DNA methylation in mice: implications for the fetal alcohol syndrome. Alcohol, Clinical and Experimental Research 15, 395-398.
    • (1991) Alcohol, Clinical and Experimental Research , vol.15 , pp. 395-398
    • Garro, A.J.1    McBeth, D.L.2    Lima, V.3    Lieber, C.S.4
  • 20
    • 0033673446 scopus 로고    scopus 로고
    • Interaction of ethanol with retinol and retinoic acid in RAR beta and GAP-43 expression
    • Grummer MA & Zachman RD (2000) Interaction of ethanol with retinol and retinoic acid in RAR beta and GAP-43 expression. Neurotoxicology and Teratology 22, 829-836.
    • (2000) Neurotoxicology and Teratology , vol.22 , pp. 829-836
    • Grummer, M.A.1    Zachman, R.D.2
  • 23
    • 0025944745 scopus 로고
    • Increased frequency of acetaldehyde-induced sister-chromatide exchanges in human lymphocytes treated with an aldehyde dehydrogenase inhibitor
    • Helander A & Lindahl-Kiessling K (1991) Increased frequency of acetaldehyde-induced sister-chromatide exchanges in human lymphocytes treated with an aldehyde dehydrogenase inhibitor. Mutatation Research 264, 103-107.
    • (1991) Mutatation Research , vol.264 , pp. 103-107
    • Helander, A.1    Lindahl-Kiessling, K.2
  • 24
    • 0031418672 scopus 로고    scopus 로고
    • High acetaldehyde levels in saliva after ethanol consumption: Methodological aspects and pathogenetic implications
    • Homann N, Jousimies-Somer H, Jokelainen K, Heine R & Salaspuro M (1997a) High acetaldehyde levels in saliva after ethanol consumption: Methodological aspects and pathogenetic implications. Carcinogenesis 18, 1739-1743.
    • (1997) Carcinogenesis , vol.18 , pp. 1739-1743
    • Homann, N.1    Jousimies-Somer, H.2    Jokelainen, K.3    Heine, R.4    Salaspuro, M.5
  • 27
    • 0035123013 scopus 로고    scopus 로고
    • Poor dental status increases the acetaldehyde production from ethanol in saliva. A possible link to the higher risk of oral cancer among alcohol consumers
    • Homann N, Tillonen J, Rintamaki H, Salaspuro M, Lindqvist C & Meurman JH (2001) Poor dental status increases the acetaldehyde production from ethanol in saliva. A possible link to the higher risk of oral cancer among alcohol consumers. Oral Oncology 37, 153-158.
    • (2001) Oral Oncology , vol.37 , pp. 153-158
    • Homann, N.1    Tillonen, J.2    Rintamaki, H.3    Salaspuro, M.4    Lindqvist, C.5    Meurman, J.H.6
  • 28
    • 0032857415 scopus 로고    scopus 로고
    • Molecular basis of multistep hepatocarcinogenesis: Genetic and epigenetic events
    • Hui AM & Makuuchi M (1999) Molecular basis of multistep hepatocarcinogenesis: genetic and epigenetic events. Scandinavian Journal of Gastroenterology 8, 737-742.
    • (1999) Scandinavian Journal of Gastroenterology , vol.8 , pp. 737-742
    • Hui, A.M.1    Makuuchi, M.2
  • 29
    • 0034597517 scopus 로고    scopus 로고
    • Frequent hypermethylation of CpG islands and loss of expression of the 14-3-3 sigma gene in human hepatocellular carcinoma
    • Iwata N, Yamamoto H, Sasaki S, Itoh F, Suzuki H, Kikuchi T, et al. (2000) Frequent hypermethylation of CpG islands and loss of expression of the 14-3-3 sigma gene in human hepatocellular carcinoma. Oncogene 19, 5298-5302.
    • (2000) Oncogene , vol.19 , pp. 5298-5302
    • Iwata, N.1    Yamamoto, H.2    Sasaki, S.3    Itoh, F.4    Suzuki, H.5    Kikuchi, T.6
  • 31
    • 0033052844 scopus 로고    scopus 로고
    • DNA hypermethylation at the D17S5 locus and reduced HIC-1 mRNA expression are associated with hepatocarcinogenesis
    • Kanai Y, Hui AM, Sun L, Ushijima S, Sakamoto M, Tsuda H & Hirohashi S (1999) DNA hypermethylation at the D17S5 locus and reduced HIC-1 mRNA expression are associated with hepatocarcinogenesis. Hepatology 29, 703-709.
    • (1999) Hepatology , vol.29 , pp. 703-709
    • Kanai, Y.1    Hui, A.M.2    Sun, L.3    Ushijima, S.4    Sakamoto, M.5    Tsuda, H.6    Hirohashi, S.7
  • 32
    • 0033988602 scopus 로고    scopus 로고
    • Aberrant DNA methylation precedes loss of heterozygosity on chromosome 16 in chronic hepatitis and liver cirrhosis
    • Kanai Y, Ushijima S, Tsuda H, Sakamoto M & Hirohashi S (2000) Aberrant DNA methylation precedes loss of heterozygosity on chromosome 16 in chronic hepatitis and liver cirrhosis. Cancer Letters 148, 73-80.
    • (2000) Cancer Letters , vol.148 , pp. 73-80
    • Kanai, Y.1    Ushijima, S.2    Tsuda, H.3    Sakamoto, M.4    Hirohashi, S.5
  • 33
    • 0033765496 scopus 로고    scopus 로고
    • Genetic instability and aberrant DNA methylation in chronic hepatitis and cirrhosis - A comprehensive study of loss of heterozygosity and microsatellite instability at 39 loci and DNA hypermethylation on 8 CpG islands in microdissected specimens from patients with hepatocellular carcinoma
    • Kondo Y, Kanai Y, Sakamoto M, Mizokami M, Ueda R & Hirohashi S (2000) Genetic instability and aberrant DNA methylation in chronic hepatitis and cirrhosis - A comprehensive study of loss of heterozygosity and microsatellite instability at 39 loci and DNA hypermethylation on 8 CpG islands in microdissected specimens from patients with hepatocellular carcinoma. Hepatology 32, 970-979.
    • (2000) Hepatology , vol.32 , pp. 970-979
    • Kondo, Y.1    Kanai, Y.2    Sakamoto, M.3    Mizokami, M.4    Ueda, R.5    Hirohashi, S.6
  • 34
    • 0017625983 scopus 로고
    • Vitamin B6 deficiency in chronic liver disease - Evidence for increased degradation of pyridoxal-5′-phosphate
    • Labadarios D, Rossouw JE, McConnell JB, Davis M & Williams R (1977) Vitamin B6 deficiency in chronic liver disease - evidence for increased degradation of pyridoxal-5′-phosphate. Gut 18, 23-27.
    • (1977) Gut , vol.18 , pp. 23-27
    • Labadarios, D.1    Rossouw, J.E.2    McConnell, J.B.3    Davis, M.4    Williams, R.5
  • 35
    • 0023039253 scopus 로고
    • Increased vitamin A in esophagus and other extrahepatic tissues after chronic ethanol consumption in the rat
    • Leo MA, Kim C & Lieber CS (1986) Increased vitamin A in esophagus and other extrahepatic tissues after chronic ethanol consumption in the rat. Alcohol, Clinical and Experimental Research 10, 487-492.
    • (1986) Alcohol, Clinical and Experimental Research , vol.10 , pp. 487-492
    • Leo, M.A.1    Kim, C.2    Lieber, C.S.3
  • 36
    • 0020318185 scopus 로고
    • Hepatic vitamin A depletion in alcoholic liver injury
    • Leo MA & Lieber CS (1982) Hepatic vitamin A depletion in alcoholic liver injury. New England Journal of Medicine 307, 597-601.
    • (1982) New England Journal of Medicine , vol.307 , pp. 597-601
    • Leo, M.A.1    Lieber, C.S.2
  • 37
    • 0007833290 scopus 로고    scopus 로고
    • Enhanced risk of upper alimentary tract cancer in patients with the alcohol dehydrogenase 3*1 allele due to increased salivary acetaldehyde following ethanol ingestion
    • Li JJ, Benesova M, Goette K, Fiehn W, Conradt C, Hoermann K, Salaspuro M & Seitz HK (2001) Enhanced risk of upper alimentary tract cancer in patients with the alcohol dehydrogenase 3*1 allele due to increased salivary acetaldehyde following ethanol ingestion. Gastroenterology 120, A-160.
    • (2001) Gastroenterology , vol.120
    • Li, J.J.1    Benesova, M.2    Goette, K.3    Fiehn, W.4    Conradt, C.5    Hoermann, K.6    Salaspuro, M.7    Seitz, H.K.8
  • 38
  • 39
    • 0028350768 scopus 로고
    • Alcohol and the liver: 1994 Update
    • Lieber CS (1994b) Alcohol and the liver: 1994 update. Gastroenterology 106, 1085-1105.
    • (1994) Gastroenterology , vol.106 , pp. 1085-1105
    • Lieber, C.S.1
  • 41
    • 0033981605 scopus 로고    scopus 로고
    • Advances in the development of retinoids as chemopreventive agents
    • Lippman SM & Lotan R (2000) Advances in the development of retinoids as chemopreventive agents. Journal of Nutrition 130, 479S-482S.
    • (2000) Journal of Nutrition , vol.130
    • Lippman, S.M.1    Lotan, R.2
  • 43
    • 0035162101 scopus 로고    scopus 로고
    • Ethanol enhances retinoic acid metabolism into polar metabolites in rat liver via induction of cytochrome P450 2E1
    • Liu C, Russell RM, Seitz HK & Wang XD (2001) Ethanol enhances retinoic acid metabolism into polar metabolites in rat liver via induction of cytochrome P450 2E1. Gastroenterology 120, 179-189.
    • (2001) Gastroenterology , vol.120 , pp. 179-189
    • Liu, C.1    Russell, R.M.2    Seitz, H.K.3    Wang, X.D.4
  • 46
    • 0033579694 scopus 로고    scopus 로고
    • Effective utilization of N2-ethyl-2′-deoxyguanosine triphosphate during DNA synthesis catalyzed by mammalian replicative DNA polymerases
    • Matsuda T, Terashima I, Matsumoto Y, Yabushita H, Matsui S & Shibutani S (1999) Effective utilization of N2-ethyl-2′-deoxyguanosine triphosphate during DNA synthesis catalyzed by mammalian replicative DNA polymerases. Biochemistry 38, 929-935.
    • (1999) Biochemistry , vol.38 , pp. 929-935
    • Matsuda, T.1    Terashima, I.2    Matsumoto, Y.3    Yabushita, H.4    Matsui, S.5    Shibutani, S.6
  • 49
    • 0035138867 scopus 로고    scopus 로고
    • Risk of head and neck cancer and the alcohol dehydrogenase 3 genotype
    • Olshan AF, Weissler MC, Watson MA & Bell DA (2001) Risk of head and neck cancer and the alcohol dehydrogenase 3 genotype. Carcinogenesis 22, 57-61.
    • (2001) Carcinogenesis , vol.22 , pp. 57-61
    • Olshan, A.F.1    Weissler, M.C.2    Watson, M.A.3    Bell, D.A.4
  • 51
    • 0028925741 scopus 로고
    • Breaks in genomic DNA and within the p53 gene are associated with hypomethylation in livers of folate/methyl-deficient rats
    • Pogribny IP, Basnakian AG, Miller BJ, Lopatina NG, Poirier LA & James SJ (1995) Breaks in genomic DNA and within the p53 gene are associated with hypomethylation in livers of folate/methyl-deficient rats. Cancer Research 55, 1894-1901.
    • (1995) Cancer Research , vol.55 , pp. 1894-1901
    • Pogribny, I.P.1    Basnakian, A.G.2    Miller, B.J.3    Lopatina, N.G.4    Poirier, L.A.5    James, S.J.6
  • 53
    • 0020064215 scopus 로고
    • Increased metabolism of retinoic acid after chronic ethanol consumption in rat liver microsomes
    • Sato M & Lieber CS (1982) Increased metabolism of retinoic acid after chronic ethanol consumption in rat liver microsomes. Archives of Biochemistry and Biophysics 213, 557-564.
    • (1982) Archives of Biochemistry and Biophysics , vol.213 , pp. 557-564
    • Sato, M.1    Lieber, C.S.2
  • 54
    • 0022995602 scopus 로고
    • Anemia in alcoholics
    • Savage D & Lindenbaum J (1986) Anemia in alcoholics. Medicine 56, 322-328.
    • (1986) Medicine , vol.56 , pp. 322-328
    • Savage, D.1    Lindenbaum, J.2
  • 56
    • 0031915076 scopus 로고    scopus 로고
    • Gastrointestinal alcohol dehydrogenases
    • Seitz HK & Oneta CM (1998) Gastrointestinal alcohol dehydrogenases. Nutrition Reviews 56, 52-60.
    • (1998) Nutrition Reviews , vol.56 , pp. 52-60
    • Seitz, H.K.1    Oneta, C.M.2
  • 57
    • 0002700294 scopus 로고
    • Effect of ethanol on procarcinogen activation
    • [RR Watson, editor]. Boca Raton, FL: CRC Press
    • Seitz HK & Oswald BR (1992) Effect of ethanol on procarcinogen activation. In Alcohol and Cancer, pp. 55-72 [RR Watson, editor]. Boca Raton, FL: CRC Press.
    • (1992) Alcohol and Cancer , pp. 55-72
    • Seitz, H.K.1    Oswald, B.R.2
  • 59
    • 0031736810 scopus 로고    scopus 로고
    • Correlation between DNA methylation and pathological changes in human hepatocellular carcinoma
    • Shen L, Fang J, Qiu D, Zhang T, Yang J, Chen S & Xiao S (1998) Correlation between DNA methylation and pathological changes in human hepatocellular carcinoma. Hepatogastroenterology 45, 1753-1759.
    • (1998) Hepatogastroenterology , vol.45 , pp. 1753-1759
    • Shen, L.1    Fang, J.2    Qiu, D.3    Zhang, T.4    Yang, J.5    Chen, S.6    Xiao, S.7
  • 60
    • 0025048632 scopus 로고
    • Immunohistochemical localization of ethanol-inducible P450 2E1 in the rat alimentary tract
    • Shimizu M, Lasker JM, Tsutsumi M & Lieber CS (1990) Immunohistochemical localization of ethanol-inducible P450 2E1 in the rat alimentary tract. Gastroenterology 99, 1044-1053.
    • (1990) Gastroenterology , vol.99 , pp. 1044-1053
    • Shimizu, M.1    Lasker, J.M.2    Tsutsumi, M.3    Lieber, C.S.4
  • 63
    • 0021970372 scopus 로고
    • Increased loss and decreased synthesis of hepatic glutathione after acute ethanol administration. Turnover studies
    • Speisky H, MacDonald A, Giles G, Orrego H & Israel Y (1985) Increased loss and decreased synthesis of hepatic glutathione after acute ethanol administration. Turnover studies. Biochemical Journal 225, 565-572.
    • (1985) Biochemical Journal , vol.225 , pp. 565-572
    • Speisky, H.1    MacDonald, A.2    Giles, G.3    Orrego, H.4    Israel, Y.5
  • 67
    • 0027682832 scopus 로고
    • The effect of ethanol on one-carbon metabolism: Increased methionine catabolism and lipotrope methyl-group wastage
    • Trimble KC, Molloy AM, Scott JM & Weir DG (1993) The effect of ethanol on one-carbon metabolism: increased methionine catabolism and lipotrope methyl-group wastage. Hepatology 18, 984-989.
    • (1993) Hepatology , vol.18 , pp. 984-989
    • Trimble, K.C.1    Molloy, A.M.2    Scott, J.M.3    Weir, D.G.4
  • 69
    • 0343526349 scopus 로고    scopus 로고
    • High salivary acetaldehyde after a moderate dose of alcohol in ALDH2-deficient subjects: Strong evidence for the local carcinogenic action of acetaldehyde
    • Vakevainen S, Tillonen J, Agarwal DP, Srivastava N & Salaspuro M (2000) High salivary acetaldehyde after a moderate dose of alcohol in ALDH2-deficient subjects: strong evidence for the local carcinogenic action of acetaldehyde. Alcohol, Clinical and Experimental Research 24, 873-877.
    • (2000) Alcohol, Clinical and Experimental Research , vol.24 , pp. 873-877
    • Vakevainen, S.1    Tillonen, J.2    Agarwal, D.P.3    Srivastava, N.4    Salaspuro, M.5
  • 70
    • 0024371483 scopus 로고
    • Rapid appearance of hypomethylated DNA in livers of rats fed cancer-promoting, methyl-deficient diets
    • Wainfan E, Dizik M, Stender M & Christman JK (1989) Rapid appearance of hypomethylated DNA in livers of rats fed cancer-promoting, methyl-deficient diets. Cancer Research 49, 4094-4097.
    • (1989) Cancer Research , vol.49 , pp. 4094-4097
    • Wainfan, E.1    Dizik, M.2    Stender, M.3    Christman, J.K.4
  • 71
    • 0001116560 scopus 로고    scopus 로고
    • Retinoids and alcoholic liver disease
    • [DP Agarwal and HK Seitz, editors]. New York: Marcel Dekker
    • Wang XD (2001) Retinoids and alcoholic liver disease. In Alcohol in Health and Disease, pp. 427-452 [DP Agarwal and HK Seitz, editors]. New York: Marcel Dekker.
    • (2001) Alcohol in Health and Disease , pp. 427-452
    • Wang, X.D.1
  • 72
    • 0031782999 scopus 로고    scopus 로고
    • Chronic alcohol intake reduces retinoic acid concentration and enhances AP-1 (c-JUN and c-FOS) expression in rat liver
    • Wang XD, Liu C, Chung J, Stickel F, Seitz HK & Russell RM (1998) Chronic alcohol intake reduces retinoic acid concentration and enhances AP-1 (c-JUN and c-FOS) expression in rat liver. Hepatology 28, 744-750.
    • (1998) Hepatology , vol.28 , pp. 744-750
    • Wang, X.D.1    Liu, C.2    Chung, J.3    Stickel, F.4    Seitz, H.K.5    Russell, R.M.6
  • 75
    • 0031709015 scopus 로고    scopus 로고
    • Alcohol related cancers and aldehyde dehydrogenase in Japanese alcoholics
    • Yokoyama A, Muramatsu T & Ohmori T (1998) Alcohol related cancers and aldehyde dehydrogenase in Japanese alcoholics. Carcinogenesis 19, 1383-1387.
    • (1998) Carcinogenesis , vol.19 , pp. 1383-1387
    • Yokoyama, A.1    Muramatsu, T.2    Ohmori, T.3
  • 78
    • 0026649374 scopus 로고
    • The onset of oncogene hypomethylation in the livers of rats fed methyl-deficient, amino acid-defined diets
    • Zapisek WF, Cronin GM, Lyn-Cook BD & Poirier LA (1992) The onset of oncogene hypomethylation in the livers of rats fed methyl-deficient, amino acid-defined diets. Carcinogenesis 13, 1869-1872.
    • (1992) Carcinogenesis , vol.13 , pp. 1869-1872
    • Zapisek, W.F.1    Cronin, G.M.2    Lyn-Cook, B.D.3    Poirier, L.A.4


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