Inhibition of fatty acid synthase-dependent neoplastic lipogenesis as the mechanism of γ-linolenic acid-induced toxicity to tumor cells: An extension to Nwankwo's hypothesis

Medical Hypotheses

Volumn 64, Issue 2, 2005, Pages 337-341

  Menendez, Javier A ^a,b   Colomer, Ramon ^c   Lupu, Ruth ^a,b  

^a 1001 Unviersity Pl Evanston I ^*  (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

^c HOSPITAL JOSEP TRUETA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOXYLASE; FATTY ACID; FATTY ACID SYNTHASE; GAMMA LINOLENIC ACID; MALONYL COENZYME A;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; CELL SURVIVAL; CONCENTRATION RESPONSE; CYTOTOXICITY; FATTY ACID OXIDATION; FATTY ACID SYNTHESIS; GENE EXPRESSION REGULATION; HUMAN; LIPID PEROXIDATION; LIPOGENESIS; LIVER CELL CULTURE; NONHUMAN; ONCOGENE; PRIORITY JOURNAL; REGULATORY MECHANISM;

BREAST NEOPLASMS; CARNITINE O-PALMITOYLTRANSFERASE; EPOXY COMPOUNDS; FATTY ACID SYNTHETASE COMPLEX; FATTY ACIDS; FEMALE; GAMMA-LINOLENIC ACID; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MALONYL COENZYME A;

EID: 11144297172     PISSN: 03069877     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mehy.2004.06.032     Document Type: Article

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