Iron availability from whey protein hydrogels: An in vitro study

Journal of Agricultural and Food Chemistry

Volumn 52, Issue 26, 2004, Pages 8137-8143

  Remondetto, Gabriel E ^a   Beyssac, Erick ^b   Subirade, Muriel ^a  

^a UNIVERSITÉ LAVAL   (Canada)

^b UNIVERSITÉ CLERMONT AUVERGNE   (France)

Author keywords

Caco 2 cells; In vitro release; Iron availability; Whey proteins hydrogels

Indexed keywords

ENZYME; FERRITIN; IRON; PANCREATIN; PEPSIN A; PROTEIN;

ABSORPTION; ALKALINITY; ARTICLE; BIOAVAILABILITY; CELL STRAIN CACO 2; CONTROLLED STUDY; DIGESTION; DISSOLUTION; FUNCTIONAL FOOD; HUMAN; HUMAN CELL; HYDROGEL; IN VITRO STUDY; INTESTINE ABSORPTION; IRON ABSORPTION; IRON KINETICS; PH; PROTEIN HYDROLYSIS; SCANNING ELECTRON MICROSCOPY; WHEY;

EID: 11144238232     PISSN: 00218561     EISSN: None     Source Type: Journal    
DOI: 10.1021/jf040286h     Document Type: Article

References (33)

1. World Health Organization. Iron Deficiency Anemia: Assessment, Prevention and Control; WHO: Geneva, Switzerland, 2001; pp 1-22.
2. Mason, J. B.; Lotfi, M.; Dalmiya, N.; Spethuramen, K.; Deitchler, M. The Micronutrient Report: Current Progress and Trends in the Control of Vitamin A, Iodine, and Iron Deficiencies; The Micronutrient Initiative: Otawa, Canada, 2001; pp 21-65.
3. Clugston, G. A.; Smith, T. E. Global nutrition problems and novel foods. Asia Pacific J. Clin. Nutr. 2002, 11, S100-S111.
4. Demment, M. W.; Young, M. M.; Senseing, R. L. Providing micronutrients through food-based solutions: A key to human and national development. J. Nutr. 2003, 133, 3879S-3885S.
5. World Health Organization. Iron Deficiency Anemia: Assessment, Prevention and Control; WHO: Geneva, Switzerland, 2001; pp 67-74.
6. Wapnir, R. A. Effect of food sources and processing on protein and mineral absorption. In Protein Nutrition and Mineral Absorption; Wapnir, R. A., Ed.; CRC Press: New York, 1990; pp 61-76.
7. Hurrell, R. F. Bioavailability of iron. Eur. J. Clin. Nutr. 1997, 51, S4-S8.
8. Hurrell, R. F. Improvement of trace element status through food fortification: technological, biological and health aspects. Nutr. Dieta 1998, 54, 40-57.
9. Allen, L. H. Advantages and limitations of iron amino acid chelates as iron fortifications. Nutr. Rev. 2002, 60, S18-S21.
10. Allain, A.-F.; Paquin, P.; Subirade, M. Relationships between conformation of β-lactoglobulin in solution and gel state as revealed by attenuated total reflection Fourier transform infrared spectroscopy. Int. J. Biol. Macromol. 1999, 26, 337-344.
11. Lefèvre, T.; Subirade, M. Molecular differences in the formation and structure of fine-stranded and particulate β-lactoglobulin gels. Biopolymers 2000, 54, 578-586.
12. Dickinson, E. Properties of emulsions stabilizided with milk proteins: overview of some recent developments. J. Dairy Sci. 1997, 80, 2607-2619.
13. Lefèvre, T.; Subirade, M. Formation of intermolecular β-sheet structures: a phenomenon relevant to protein fill structure at oil-water interfaces of emulsions. J. Colloids Interface Sci. 2003, 263, 59-67.
14. Beaulieu, L.; Savoie, L.; Paquin, P.; Subirade, M. Elaboration and characterization of whey protein beads by an emulsification/cold gelation process: application for the protection of retinol. Biomacromolecules 2002, 3, 239-248.
15. Remondetto, G. E.; Paquin, P.; Subirade, M. Cold gelation of β-lactoglobulin in the presence of iron. J. Food Sci. 2002, 67, 586-595.
16. 2+-Induced gelation of pre-heated whey protein isolate. J. Food Sci. 1993, 58, 867-871.
17. 2+-induced β-lactoglobulin cold gelation: an interactions story. Biopolymers 2003, 69, 461-469.
18. Hilgendorf, C.; Spahn-Langguth, H.; Regardh, C. G.; Lipka, E.; Amidon, G. L.; Langguth, P. Caco-2 versus caco-2/HT29-MTX co-cultured cell lines: permeabilities via diffusion, inside- and outside-directed carrier-mediated transport. J. Pharm. Sci. 2000, 89, 63-75.
19. Nunez, M. T.; Osorio, A.; Tapia, V.; Vergara, A.; Mura, C. V. Iron-induced oxidative stress up-regulates calreticulin levels in intestinal epithelial (caco-2) cells. J. Cell. Biochem. 2001, 82, 660-665.
20. Siddiqi, S.; Kumar, N.; Nutting, D.; Mansbach, C. Nutrient absorption. Curr. Opin. Gastroenterol. 2001, 17, 110-117.
21. Swain, J.; Tabatabai, L.; Reddy, M. Histidine content of low-molecular-weight beef proteins influences nonheme iron Bioavailability in Caco-2 cells. J. Nutr. 2002, 132, 245-251.
22. European Pharmacopoeia. Dissolution test for transdermal patch. In European Pharmacopoeia; Paris, France, 2003; pp 194-196.
23. The United States Pharmacopeial Convention. General Tests and Assays; USP Convention Inc.: Rockville, MD, 2004; pp 1-6.
24. The United States Pharmacopeial Convention. Test Solutions; USP Convention Inc.: Rockville, MD, 2004; pp 9-23.
25. Dechert, R. E.; Cerny, J. C.; Bartlett, R. H. Measurement of elemental nitrogen by chemiluminescence: an evaluation of the Antek Nitrogen Analyzer System. J. Parenteral Enteral Nutr. 1990, 14, 195-197.
26. Puyfoulhoux, G.; Rouanet, J.-M.; Besançon, P.; Baroux, B.; Baccou, J.-C.; Caporiccio, B. Iron availability from iron-fortified spirulina by an in vitro digestion/caco-2 cell culture model. J. Agric. Food Chem. 2001, 49, 1625-1629.
27. Qiu, Y.; Park, K. Environment-sensitive hydrogels for drug delivery. Adv. Drug Deliv. Rev. 2001, 53, 321-339.
28. Gupta, P.; Vermain, K.; Garg, S. Hydrogels: from controlled release to pH-responsive drug delivery. Drug Discovery Today 2002, 7, 569-579.
29. Germann, W. J.; Stanfield, C. L. The digestive system. In Principles of Human Physiology; Germann, W. J., Stanfield, C. L., Eds.; Benjamin Cummings: San Francisco, CA, 2001; pp 601-638.
30. Crosby, W. H. The control of iron balance by the intestinal mucosa. Blood 1963, 22, 441-449.
31. Whittaker, P.; Skikne, B. S.; Covell, A. M.; Flowers, C.; Cooke, A.; Lynch, S. R.; Cook, J. D. Duodenal iron proteins in idiopathic hemocromatosis. J. Clin. Invest. 1989, 83, 261-267.
32. Brannon-Peppas, L. Recent advances on the use of biodegradable microparticles and nanoparticles in controlled drug delivery. Int. J. Pharm. 1995, 116, 1-9.
33. Jacobs, I. C.; Mason, N. S. Polymer delivery systems concepts. In Polymeric Delivery Systems; El-Nokaky, M. A., Piatt, D. M., Charpentier, B. A., Eds.; American Chemical Society: Washington, DC, 1993; pp 1-17.