The effects of sciatic nerve axotomy on spinal motoneurons in neonatal Bax-deficient mice

Neuroscience Research

Volumn 44, Issue 4, 2002, Pages 439-446

  Kinugasa, Tomonori ^a   Ozaki, Shigeru ^a   Hamanaka, Souji ^a   Kudo, Norio ^a  

^a UNIVERSITY OF TSUKUBA   (Japan)

Author keywords

AChE; Apoptosis; Axotomy; Bax; Motoneuron; Spinal cord

Indexed keywords

ACETYLCHOLINESTERASE; PROTEIN BAX;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL ASSAY; CELL DEATH; CELL FUNCTION; CELL LOSS; CONTROLLED STUDY; HISTOCHEMISTRY; MOUSE; NERVE FIBER TRANSECTION; NONHUMAN; PERINATAL PERIOD; PRIORITY JOURNAL; PROTEIN DEFICIENCY; SCIATIC NERVE; SPINAL CORD MOTONEURON; STAINING; WILD TYPE;

ACETYLCHOLINESTERASE; ANIMALS; ANIMALS, NEWBORN; APOPTOSIS; AXOTOMY; BCL-2-ASSOCIATED X PROTEIN; CARBOCYANINES; CELL DIFFERENTIATION; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION, DEVELOPMENTAL; MICE; MICE, KNOCKOUT; MOTOR NEURONS; MUSCULAR ATROPHY, SPINAL; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; RETROGRADE DEGENERATION; SCIATIC NERVE; SPINAL CORD;

EID: 0036890508     PISSN: 01680102     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-0102(02)00171-2     Document Type: Article

References (32)

1. Baba N., Koji T., Itoh M., Mizuno A. Reciprocal changes in the expression of Bcl-2 and Bax in hypoglossal nucleus after axotomy in adult rats: possible involvement in the induction of neuronal cell death. Brain Res. 827:1999;122-129.
2. Bar-Peled O., Knudson M., Korsmeyer S.J., Rothstein J.D. Motor neuron degeneration is attenuated in bax-deficient neurons in vitro. J. Neurosci. Res. 55:1999;542-556.
3. Baulac M., Meininger V. Postnatal development and cell death in the sciatic motor nucleus of the mouse. Exp. Brain Res. 50:1983;107-116.
4. Dargusch R., Piasecki D., Tan S., Liu Y., Schubert D. The role of Bax in glutamate-induced nerve cell death. J. Neurochem. 76:2001;295-301.
5. Deckwerth T.L., Elliott J.L., Knudson C.M., Johnson E.M. Jr, Snider W.D., Korsmeyer S.J. BAX is required for neuronal death after trophic factor deprivation and during development. Neuron. 17:1996;401-411.
6. Di Patre P.L., Mathes C.W., Butcher L.L. Differential visualization of cholinesterasic neuronal somata and fibers by use of modifications of acetylcholinesterase pharmacohistochemistry. J. Histochem. Cytochem. 41:1993;129-135.
7. Dubois-Dauphin M., Frankowski H., Tsujimoto Y., Huarte J., Martinou J.C. Neonatal motoneurons overexpressing the bcl-2 protooncogene in transgenic mice are protected from axotomy-induced cell death. Proc. Natl. Acad. Sci. USA. 91:1994;3309-3313.
8. Fernandes K.J., Kobayashi N.R., Jasmin B.J., Tetzlaff W. Acetylcholinesterase gene expression in axotomized rat facial motoneurons is differentially regulated by neurotrophins: correlation with trkB and trkC mRNA levels and isoforms. J. Neurosci. 18:1998;9936-9947.
9. Flanagan A.E., Fernandes K.J., Kobayashi N.R., Jasmin B.J., Tetzlaff W. Differentiation and degeneration in the motor horn of the foetal mouse. J. Morphol. 129:1969;281-305.
10. Green D.R., Reed J.C. Mitochondria and apoptosis. Science. 281:1998;1309-1312.
11. Hamburger V. Regression versus peripheral control of differentiation in motor hypoplasia. Am. J. Anat. 102:1958;365-409.
12. Hollyday M., Hamburger V. Reduction of the naturally occurring motor neuron loss by enlargement of the periphery. J. Comp. Neurol. 170:1976;311-320.
13. Kashihara Y., Kuno M., Miyata Y. Cell death of axotomized motoneurones in neonatal rats, and its prevention by peripheral reinnervation. J. Physiol. 386:1987;135-148.
14. Knudson C.M., Tung K.S., Tourtellotte W.G., Brown G.A., Korsmeyer S.J., Kashihara Y., Kuno M., Miyata Y. Bax-deficient mice with lymphoid hyperplasia and male germ cell death. Science. 270:1995;96-99.
15. Li L., Oppenheim R.W., Lei M., Houenou L.J. Neurotrophic agents prevent motoneuron death following sciatic nerve section in the neonatal mouse. J. Neurobiol. 25:1994;759-766.
16. McHanwell S., Biscoe T.J., Lowrie M.B., Vrbova G., Li L., Oppenheim R.W., Lei M., Houenou L.J. The localization of motoneurons supplying the hindlimb muscles of the mouse. Philos. Trans. R. Soc. Lond. B Biol. Sci. 293:1981;477-508.
17. Merry D.E., Korsmeyer S.J., Mendell L.M., Johnson R.D., Munson J.B. Bcl-2 gene family in the nervous system. Annu. Rev. Neurosci. 20:1997;245-267.
18. Miyata Y., Kashihara Y., Homma S., Kuno M. Effects of nerve growth factor on the survival and synaptic function of Ia sensory neurons axotomized in neonatal rats. J. Neurosci. 6:1986;2012-2018.
19. Nakagawa T., Zhu H., Morishima N., Li E., Xu J., Yankner B.A., Yuan J. Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta. Nature. 403:2000;98-103.
20. Oltvai Z.N., Milliman C.L., Korsmeyer S.J. Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell. 74:1993;609-619.
21. Oppenheim R.W. The absence of significant postnatal motoneuron death in the brachial and lumbar spinal cord of the rat. J. Comp. Neurol. 246:1986;281-286.
22. Oppenheim R.W. Cell death during development of the nervous system. Annu. Rev. Neurosci. 14:1991;453-501.
23. Oppenheim R.W., Houenou L., Pincon-Raymond M., Powell J.A., Rieger F., Standish L.J. The development of motoneurons in the embryonic spinal cord of the mouse mutant, muscular dysgenesis (mdg/mdg): survival, morphology, and biochemical differentiation. Dev. Biol. 114:1986;426-436.
24. Rabacchi S.A., Bonfanti L., Liu X.H., Maffei L. Apoptotic cell death induced by optic nerve lesion in the neonatal rat. J. Neurosci. 14:1994;5292-5301.
25. Rossiter J.P., Riopelle R.J., Bisby M.A., Oppenheim R.W., Houenou L., Pincon-Raymond M., Powell J.A., Rieger F., Standish L.J. Axotomy-induced apoptotic cell death of neonatal rat facial motoneurons: time course analysis and relation to NADPH-diaphorase activity. Exp. Neurol. 138:1996;33-44.
26. Scaffidi C., Schmitz I., Krammer P.H., Peter M.E. The role of c-FLIP in modulation of CD95-induced apoptosis. J. Biol. Chem. 274:1999;1541-1548.
27. Spencer R.F., Baker R. Histochemical localization of acetylcholinesterase in relation to motor neurons and internuclear neurons of the cat abducens nucleus. J. Neurocytol. 15:1986;137-154.
28. Tago H., Kimura H., Maeda T. Visualization of detailed acetylcholinesterase fiber and neuron staining in rat brain by a sensitive histochemical procedure. J. Histochem. Cytochem. 34:1986;1431-1438.
29. Tanaka H., Landmesser L.T. Cell death of lumbosacral motoneurons in chick, quail, and chick-quail chimera embryos: a test of the quantitative matching hypothesis of neuronal cell death. J. Neurosci. 6:1986;2889-2899.
30. Tetzlaff W., Kreutzberg G.W. Enzyme changes in the rat facial nucleus following a conditioning lesion. Exp. Neurol. 85:1984;547-564.
31. Vejsada R., Sagot Y., Kato A.C. Quantitative comparison of the transient rescue effects of neurotrophic factors on axotomized motoneurons in vivo. Eur. J. Neurosci. 7:1995;108-115.
32. White F.A., Keller-Peck C.R., Knudson C.M., Korsmeyer S.J., Snider W.D. Widespread elimination of naturally occurring neuronal death in Bax-deficient mice. J. Neurosci. 18:1998;1428-1439.