Metalloenediynes: Advances in the design of thermally and photochemically activated diradical formation for biomedical applications

Current Topics in Medicinal Chemistry

Volumn 4, Issue 15, 2004, Pages 1637-1654

  Bhattacharyya, Sibaprasad ^a   Zaleski, Jeffrey M ^a  

^a INDIANA UNIVERSITY   (United States)

Author keywords

Bergman cyclization; Diradical; DNA cleavage; Enediyne; H antom abstraction; Metalloenediynes

Indexed keywords

AMMONIA; ANTINEOPLASTIC ANTIBIOTIC; BENZENE DERIVATIVE; BENZOQUINONE DERIVATIVE; BENZYL DERIVATIVE; BROMINE DERIVATIVE; CALICHEAMICIN; CALICHEAMICIN GAMMA1; CHLORIDE ION; COPPER COMPLEX; CYCLOPENTADIENE DERIVATIVE; DYNEMICIN A; ESPERAMICIN; ESPERAMICIN A1; HYDROQUINONE DERIVATIVE; INORGANIC COMPOUND; LEWIS ACID; MAGNESIUM DERIVATIVE; MERCURY DERIVATIVE; METALLOENEDIYNE DERIVATIVE; MOLYBDENUM COMPLEX; ORGANIC COMPOUND; PALLADIUM COMPLEX; PLATINUM COMPLEX; RADICAL; RUTHENIUM COMPLEX; SILVER DERIVATIVE; UNCLASSIFIED DRUG; UNINDEXED DRUG; VINYL DERIVATIVE; ZINC COMPLEX;

ANNULATION REACTION; ANTINEOPLASTIC ACTIVITY; BIOMEDICINE; COMPLEX FORMATION; CYCLIZATION; DRUG ACTIVATION; DRUG DESIGN; DRUG STRUCTURE; ELECTRICITY; GEOMETRY; METAL BINDING; MOLECULAR STABILITY; PHOTOCHEMISTRY; PRACTICE GUIDELINE; PROTEIN TARGETING; REVIEW; STRUCTURE ACTIVITY RELATION;

ALKYNES; ANTIBIOTICS, ANTINEOPLASTIC; BIOCOMPATIBLE MATERIALS; BIOMEDICAL ENGINEERING; CYCLIZATION; DRUG DESIGN; FREE RADICALS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; ORGANOMETALLIC COMPOUNDS; PHOTOCHEMISTRY;

EID: 10844265238     PISSN: 15680266     EISSN: None     Source Type: Journal    
DOI: 10.2174/1568026043387403     Document Type: Review

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