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Volumn 38, Issue 10, 2003, Pages 1023-1029

The Hypotriglyceridemic Effect of Dietary n-3 FA Is Associated with Increased β-Oxidation and Reduced Leptin Expression

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL ORGANS; GENES; INSULIN; NUTRITION; OILS AND FATS; OXIDATION; PROTEINS; RNA; TISSUE;

EID: 10744228334     PISSN: 00244201     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11745-006-1156-z     Document Type: Article
Times cited : (112)

References (44)
  • 1
    • 0030695221 scopus 로고    scopus 로고
    • Molecular and Cellular Determinants of Triglyceride Availability
    • Sebokova, E., and Klimes, I. (1997) Molecular and Cellular Determinants of Triglyceride Availability, Ann. NY Acad. Sci. 827, 200-214.
    • (1997) Ann. NY Acad. Sci. , vol.827 , pp. 200-214
    • Sebokova, E.1    Klimes, I.2
  • 4
    • 0009652566 scopus 로고
    • Dietary Fish Oil in Hyperlipidemia and Impaired Insulin Action - The Experimental Approach, A Minireview
    • (Hanefeld, M., Jaross, W., and Dude, H., eds.), Fisher Verlag, Jena, Germany
    • Klimes, I., Sebokova, E., and Minchenko, A. (1991) Dietary Fish Oil in Hyperlipidemia and Impaired Insulin Action-The Experimental Approach, A Minireview, in Lipoproteins and Atherosclerosis (Hanefeld, M., Jaross, W., and Dude, H., eds.), pp. 56-62, Fisher Verlag, Jena, Germany
    • (1991) Lipoproteins and Atherosclerosis , pp. 56-62
    • Klimes, I.1    Sebokova, E.2    Minchenko, A.3
  • 5
    • 0029935392 scopus 로고    scopus 로고
    • Polyunsaturated Fatty Acid Regulation of Hepatic Gene Transcription
    • Clarke, S.D., and Jump, D.B. (1996) Polyunsaturated Fatty Acid Regulation of Hepatic Gene Transcription, Lipids 31, S7-S11.
    • (1996) Lipids , vol.31
    • Clarke, S.D.1    Jump, D.B.2
  • 6
    • 0030572723 scopus 로고    scopus 로고
    • Regulation of Gene Expression for Lipogenic Enzymes in the Liver and Adipose Tissue of Hereditary Hypertriglyceridemic, Insulin Resistant Rats: Effect of Dietary Sucrose and Marine Fish Oil
    • Sebökova, E., Klimes, I., Gasperikova, D., Bohov, P., Langer, P., Lavau, M., and Clandinin, M.T. (1996) Regulation of Gene Expression for Lipogenic Enzymes in the Liver and Adipose Tissue of Hereditary Hypertriglyceridemic, Insulin Resistant Rats: Effect of Dietary Sucrose and Marine Fish Oil, Biochim. Biophys. Acta 1303, 56-62.
    • (1996) Biochim. Biophys. Acta , vol.1303 , pp. 56-62
    • Sebökova, E.1    Klimes, I.2    Gasperikova, D.3    Bohov, P.4    Langer, P.5    Lavau, M.6    Clandinin, M.T.7
  • 7
    • 0027240172 scopus 로고
    • Dietary Supplementation of Very Long Chain n-3 Fatty Acids Decreases Whole Body Lipid Utilization in the Rat
    • Rustan, A.C., Hustvedt, B.E., and Drevon, C.A. (1993) Dietary Supplementation of Very Long Chain n-3 Fatty Acids Decreases Whole Body Lipid Utilization in the Rat, J. Lipid Res. 34, 1299-1309.
    • (1993) J. Lipid Res. , vol.34 , pp. 1299-1309
    • Rustan, A.C.1    Hustvedt, B.E.2    Drevon, C.A.3
  • 9
    • 0032559663 scopus 로고    scopus 로고
    • Post-prandial Decrease in Plasma Unesterified Fatty Acids during n-3 Fatty Acid Feeding Is Not Caused by Accumulation of Fatty Acids in Adipose Tissue
    • Rustan, A.C., Hustvedt, B.E., and Drevon, C.A. (1998) Post-prandial Decrease in Plasma Unesterified Fatty Acids During n-3 Fatty Acid Feeding Is Not Caused by Accumulation of Fatty Acids in Adipose Tissue, Biochim. Biophys. Acta 1390, 245-257.
    • (1998) Biochim. Biophys. Acta , vol.1390 , pp. 245-257
    • Rustan, A.C.1    Hustvedt, B.E.2    Drevon, C.A.3
  • 12
    • 0032982919 scopus 로고    scopus 로고
    • 3-Thia Fatty Acid Treatment, in Contrast to Eicosapentaenoic Acid and Starvation, Induces Gene Expression of Carnitine Palmitoyltransferase-II in Rat Liver
    • Madsen, L., and Berge R.K. (1999) 3-Thia Fatty Acid Treatment, in Contrast to Eicosapentaenoic Acid and Starvation, Induces Gene Expression of Carnitine Palmitoyltransferase-II in Rat Liver, Lipids 34, 447-456.
    • (1999) Lipids , vol.34 , pp. 447-456
    • Madsen, L.1    Berge, R.K.2
  • 13
    • 0035345532 scopus 로고    scopus 로고
    • Skeletal Muscle Triglyceride: An Aspect of Regional Adiposity and Insulin Resistance
    • Kelley, D.E., and Goodpaster, B.H. (2001) Skeletal Muscle Triglyceride: An Aspect of Regional Adiposity and Insulin Resistance, Diabetes Care 24, 933-941.
    • (2001) Diabetes Care , vol.24 , pp. 933-941
    • Kelley, D.E.1    Goodpaster, B.H.2
  • 14
    • 0032771771 scopus 로고    scopus 로고
    • Co-ordinate Induction of Peroxisomal Acyl-CoA Oxidase and UCP-3 by Dietary Fish Oil: A Mechanism for Decreased Body Fat Deposition
    • Baillie, R.A., Takada, R., Nakamura, M., and Clarke, S.D. (1999) Co-ordinate Induction of Peroxisomal Acyl-CoA Oxidase and UCP-3 by Dietary Fish Oil: A Mechanism for Decreased Body Fat Deposition, Prostaglandins Leukot. Essent. Fatty Acids 60, 351-356.
    • (1999) Prostaglandins Leukot. Essent. Fatty Acids , vol.60 , pp. 351-356
    • Baillie, R.A.1    Takada, R.2    Nakamura, M.3    Clarke, S.D.4
  • 16
    • 0033514956 scopus 로고    scopus 로고
    • Regulation of Fatty Acid Homeostasis in Cells: Novel Role of Leptin
    • Unger, R.H., Zhou, Y.T., and Orci, L. (1999) Regulation of Fatty Acid Homeostasis in Cells: Novel Role of Leptin, Proc. Natl. Acad. Sci. USA 96, 2327-2332.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 2327-2332
    • Unger, R.H.1    Zhou, Y.T.2    Orci, L.3
  • 17
    • 0035125917 scopus 로고    scopus 로고
    • Lipotoxicity of β-Cells in Obesity and in Other Causes of Fatty Acid Spillover
    • Unger, R.H, and Zhou, Y.T. (2001) Lipotoxicity of β-Cells in Obesity and in Other Causes of Fatty Acid Spillover, Diabetes 50, S118-S121.
    • (2001) Diabetes , vol.50
    • Unger, R.H.1    Zhou, Y.T.2
  • 18
    • 0034682474 scopus 로고    scopus 로고
    • Leptin, Troglitazone and Expression of Sterol Regulatory Element Binding Proteins in Liver and Pancreatic Islets
    • Kakuma, T., Lee, Y., Higa, M., Wang, Z.-W., Pan, W., Shimomura, I., and Unger, R.H. (2000) Leptin, Troglitazone and Expression of Sterol Regulatory Element Binding Proteins in Liver and Pancreatic Islets, Proc. Natl. Acad. Sci. USA 97, 8536-8541.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 8536-8541
    • Kakuma, T.1    Lee, Y.2    Higa, M.3    Wang, Z.-W.4    Pan, W.5    Shimomura, I.6    Unger, R.H.7
  • 20
    • 0029078449 scopus 로고
    • Regulated Expression of the Obese Gene Product (leptin) in White Adipose Tissue and 3T3-L1 Adipocytes
    • MacDouglas, O.A., Hwang, C.S., and Fan, H. (1995) Regulated Expression of the Obese Gene Product (leptin) in White Adipose Tissue and 3T3-L1 Adipocytes, Proc. Natl. Acad. Sci. USA 92, 9034-9037.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 9034-9037
    • MacDouglas, O.A.1    Hwang, C.S.2    Fan, H.3
  • 21
    • 0029859099 scopus 로고    scopus 로고
    • Leptin: The Tale of an Obesity Gene
    • Caro, J., Sinha, M., and Kolaczynski, J. (1996) Leptin: The Tale of an Obesity Gene, Diabetes 45, 1455-1462.
    • (1996) Diabetes , vol.45 , pp. 1455-1462
    • Caro, J.1    Sinha, M.2    Kolaczynski, J.3
  • 22
    • 0028841201 scopus 로고
    • Augmented Expression of the Obese Gene in the Adipose Tissue from Rats Fed High Fat Diet
    • Masuzaki, H., Ogawa, Y., and Hosoda, K. (1995) Augmented Expression of the Obese Gene in the Adipose Tissue from Rats Fed High Fat Diet, Biochem. Biophys. Res. Commun. 216, 355-358.
    • (1995) Biochem. Biophys. Res. Commun. , vol.216 , pp. 355-358
    • Masuzaki, H.1    Ogawa, Y.2    Hosoda, K.3
  • 23
    • 0030700020 scopus 로고    scopus 로고
    • Site-Specific Regulation of Gene Expression by n-3 Polyunsaturated Fatty Acids in Rat White Adipose Tissues
    • Raclot, T., Groscolas, R., Langin, D., and Ferre, P. (1997) Site-Specific Regulation of Gene Expression by n-3 Polyunsaturated Fatty Acids in Rat White Adipose Tissues, J. Lipid Res. 38, 1963-1972.
    • (1997) J. Lipid Res. , vol.38 , pp. 1963-1972
    • Raclot, T.1    Groscolas, R.2    Langin, D.3    Ferre, P.4
  • 26
    • 0027168819 scopus 로고
    • High Fat Diet-Induced Insulin Resistance: Lessons and Implications from Animal Studies
    • Storlien, L.H., Pan, D.A., Kriketos, A.D., and Baur, L.A. (1993) High Fat Diet-Induced Insulin Resistance: Lessons and Implications from Animal Studies, Ann. N. Y. Acad. Sci. 683, 82-90.
    • (1993) Ann. N. Y. Acad. Sci. , vol.683 , pp. 82-90
    • Storlien, L.H.1    Pan, D.A.2    Kriketos, A.D.3    Baur, L.A.4
  • 27
    • 0026040907 scopus 로고
    • Development of Muscle Insulin Resistance after Liver Insulin Resistance in High Fat Fed Rats
    • Kraegen, E.W., Clark, P.W., Jenkins, A.B., Daley, E.A., Chisholm, D.J., and Storlien, L.H. (1991) Development of Muscle Insulin Resistance After Liver Insulin Resistance in High Fat Fed Rats, Diabetes 40, 1397-1403.
    • (1991) Diabetes , vol.40 , pp. 1397-1403
    • Kraegen, E.W.1    Clark, P.W.2    Jenkins, A.B.3    Daley, E.A.4    Chisholm, D.J.5    Storlien, L.H.6
  • 28
    • 0032467529 scopus 로고    scopus 로고
    • The Effect of the New Oral Hypoglycemic Agent A-4166 on Glucose Turnover in the High Fat Diet Induced and/or in the Hereditary Insulin Resistance of Rats
    • Klimes, I., Mitkova, A., Gasperikova, D., Ukropec, J., Liska, B., Bohov, P., Stanek, J., and Sebokova, E. (1998) The Effect of the New Oral Hypoglycemic Agent A-4166 on Glucose Turnover in the High Fat Diet Induced and/or in the Hereditary Insulin Resistance of Rats, Arch. Physiol. Biochem. 106, 325-332.
    • (1998) Arch. Physiol. Biochem. , vol.106 , pp. 325-332
    • Klimes, I.1    Mitkova, A.2    Gasperikova, D.3    Ukropec, J.4    Liska, B.5    Bohov, P.6    Stanek, J.7    Sebokova, E.8
  • 29
    • 0023277545 scopus 로고
    • Single-Step Method for RNA Isolation by Acid Guanidinium Thiocyanate-Phenol-Chloroform Extraction
    • Chomczynski, P., and Sacchi, N. (1987) Single-Step Method for RNA Isolation by Acid Guanidinium Thiocyanate-Phenol-Chloroform Extraction, Anal. Biochem 162, 156-159.
    • (1987) Anal. Biochem. , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 30
    • 0027498292 scopus 로고
    • Docosahexaenoic Acid Shows No Triglyceride-Lowering Effects but Increases the Peroxisomal Fatty Acid Oxidation in Liver of Rats
    • Willumsen, N., Hexeberg, S., Skorve, J., Lundquist, M., and Berge, R.K. (1993) Docosahexaenoic Acid Shows No Triglyceride-Lowering Effects but Increases the Peroxisomal Fatty Acid Oxidation in Liver of Rats, J. Lipid Res. 34, 13-22.
    • (1993) J. Lipid Res. , vol.34 , pp. 13-22
    • Willumsen, N.1    Hexeberg, S.2    Skorve, J.3    Lundquist, M.4    Berge, R.K.5
  • 31
    • 0019798351 scopus 로고
    • The Effect of Fasting on the Activity of Liver Carnitine Palmitoyltransferase and Its Inhibition by Malonyl-CoA
    • Bremer, J. (1981) The Effect of Fasting on the Activity of Liver Carnitine Palmitoyltransferase and Its Inhibition by Malonyl-CoA, Biochim. Biophys. Acta 665, 628-631.
    • (1981) Biochim. Biophys. Acta , vol.665 , pp. 628-631
    • Bremer, J.1
  • 32
    • 0028031524 scopus 로고
    • A Sensitive Assay of Acyl-CoA Oxidase by Coupling with β-Oxidation Multienzyme Complex
    • Souri, M., Aoyama, T., and Hashimoto, T. (1994) A Sensitive Assay of Acyl-CoA Oxidase by Coupling with β-Oxidation Multienzyme Complex, Anal. Biochem. 221, 362-367.
    • (1994) Anal. Biochem. , vol.221 , pp. 362-367
    • Souri, M.1    Aoyama, T.2    Hashimoto, T.3
  • 33
    • 0020624753 scopus 로고
    • Observations on the Affinity for Carnitine and Malonyl-CoA Sensitivity of Carnitine Palmitoyltransferase-1 in Animal and Human Tissues
    • McGarry, J.D., Mills, S.E., Long, C.S., and Foster, D.W. (1983) Observations on the Affinity for Carnitine and Malonyl-CoA Sensitivity of Carnitine Palmitoyltransferase-1 in Animal and Human Tissues, Biochem. J. 214, 21-28.
    • (1983) Biochem. J. , vol.214 , pp. 21-28
    • McGarry, J.D.1    Mills, S.E.2    Long, C.S.3    Foster, D.W.4
  • 34
    • 0031908208 scopus 로고    scopus 로고
    • Phytanic Acid and Pristanic Acid Are Oxidized by Sequential Peroxisomal and Mitochondrial Reactions in Cultured Fibroblasts
    • Verhoeven, N.M., Roe, D.S., Kok, R.M., Wanders, R.J., Jakobs, C., and Roe, C.R. (1998) Phytanic Acid and Pristanic Acid Are Oxidized by Sequential Peroxisomal and Mitochondrial Reactions in Cultured Fibroblasts, J. Lipid Res. 39, 66-74.
    • (1998) J. Lipid Res. , vol.39 , pp. 66-74
    • Verhoeven, N.M.1    Roe, D.S.2    Kok, R.M.3    Wanders, R.J.4    Jakobs, C.5    Roe, C.R.6
  • 35
    • 0032724029 scopus 로고    scopus 로고
    • Eicosapentaenoic and Docosahexaenoic Acid Affect Mitochondrial and Peroxisomal Fatty Acid Oxidation in Relation to Substrate Preference
    • Madsen, L., Rustan, A.C., Vaagenes, H., Berge, K., Dyroy, E., and Berge, R.K. (1999) Eicosapentaenoic and Docosahexaenoic Acid Affect Mitochondrial and Peroxisomal Fatty Acid Oxidation in Relation to Substrate Preference, Lipids 34, 951-963.
    • (1999) Lipids , vol.34 , pp. 951-963
    • Madsen, L.1    Rustan, A.C.2    Vaagenes, H.3    Berge, K.4    Dyroy, E.5    Berge, R.K.6
  • 39
    • 0033214097 scopus 로고    scopus 로고
    • In Contrast with Docosahexaenoic Acid, Eicosapentaenoic Acid and Hypolipidaemic Derivatives Decrease Hepatic Synthesis and Secretion of Triacylglycerol by Decreased Diacylglycerol Acyltransferase Activity and Stimulation of Fatty Acid Oxidation
    • Berge, R.K., Madsen, L., Vaagenes, H., Tronstad, K.J., Gottlicher, M., and Rustan, A.C. (1999) In Contrast with Docosahexaenoic Acid, Eicosapentaenoic Acid and Hypolipidaemic Derivatives Decrease Hepatic Synthesis and Secretion of Triacylglycerol by Decreased Diacylglycerol Acyltransferase Activity and Stimulation of Fatty Acid Oxidation, Biochem. J. 343, 191-197.
    • (1999) Biochem. J. , vol.343 , pp. 191-197
    • Berge, R.K.1    Madsen, L.2    Vaagenes, H.3    Tronstad, K.J.4    Gottlicher, M.5    Rustan, A.C.6
  • 40
    • 0030775161 scopus 로고    scopus 로고
    • Dietary Fatty Acids Influence the Activity and Metabolic Control of Mitochondrial Carnitine Palmitoyltransferase-I in Rat Heart and Skeletal Muscle
    • Power, G.W., and Newsholme, E.A. (1997) Dietary Fatty Acids Influence the Activity and Metabolic Control of Mitochondrial Carnitine Palmitoyltransferase-I in Rat Heart and Skeletal Muscle, J. Nutr. 127, 2142-2150.
    • (1997) J. Nutr. , vol.127 , pp. 2142-2150
    • Power, G.W.1    Newsholme, E.A.2
  • 41
    • 0037122766 scopus 로고    scopus 로고
    • Leptin Stimulates Fatty-Acid Oxidation by Activating AMP-Activated Protein Kinase
    • Minokoshi, Y., Kim, Y.B., Peroni, O.D., Fryer, L.G., Muller, C., Carling, D., and Kahn, B.B. (2002) Leptin Stimulates Fatty-Acid Oxidation by Activating AMP-Activated Protein Kinase, Nature 415, 339-343.
    • (2002) Nature , vol.415 , pp. 339-343
    • Minokoshi, Y.1    Kim, Y.B.2    Peroni, O.D.3    Fryer, L.G.4    Muller, C.5    Carling, D.6    Kahn, B.B.7
  • 42
    • 0028821861 scopus 로고
    • The ob Gene and Insulin. A Relationship Leading to Clues to the Understanding of Obesity
    • Cusin, I., Sainsbury, A., Doyle, P., Rohner-Jeanrenaud, F., and Jeanrenaud, B. (1995) The ob Gene and Insulin. A Relationship Leading to Clues to the Understanding of Obesity, Diabetes 44, 1467-1470.
    • (1995) Diabetes , vol.44 , pp. 1467-1470
    • Cusin, I.1    Sainsbury, A.2    Doyle, P.3    Rohner-Jeanrenaud, F.4    Jeanrenaud, B.5
  • 43
    • 0029092010 scopus 로고
    • Diet- and Diabetes-Induced Changes of ob Gene Expression in Rat Adipose Tissue
    • Becker, D.J., Ongemba, L.N., Brichard, V., Henquin, J.C., and Brichard, S.M. (1995) Diet- and Diabetes-Induced Changes of ob Gene Expression in Rat Adipose Tissue, FEBS Lett. 371, 324-328.
    • (1995) FEBS Lett. , vol.371 , pp. 324-328
    • Becker, D.J.1    Ongemba, L.N.2    Brichard, V.3    Henquin, J.C.4    Brichard, S.M.5
  • 44
    • 0030883332 scopus 로고    scopus 로고
    • Effects of Prolonged Hyperinsulinemia on Serum Leptin in Normal Human Subjects
    • Boden, G., Chen, X., Kolaczynski, J.W., and Polansky, M. (1997) Effects of Prolonged Hyperinsulinemia on Serum Leptin in Normal Human Subjects, J. Clin. Invest. 100, 1107-113.
    • (1997) J. Clin. Invest. , vol.100 , pp. 1107-1113
    • Boden, G.1    Chen, X.2    Kolaczynski, J.W.3    Polansky, M.4


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