Control of ceramide-induced apoptosis by IGF-1: Involvement of PI-3 kinase, caspase-3 and catalase

Cell Death and Differentiation

Volumn 9, Issue 6, 2002, Pages 682-692

  Kondo, T ^a   Kitano, T ^a   Iwai, K ^a   Watanabe, M ^a   Taguchi, Y ^a   Yabu, T ^a   Umehara, H ^a   Domae, N ^a   Uchiyama, T ^a   Okazaki, T ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

Apoptosis; Caspase 3; Catalase; Ceramide; Insulin like growth factor 1; Oxidative stress; Phosphatidylinositol 3 kinase

Indexed keywords

AMITROLE; CASPASE 3; CASPASE 3 INHIBITOR; CATALASE; CERAMIDE DERIVATIVE; CYTOCHROME C; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; SOMATOMEDIN C; WORTMANNIN; ACETYL ASPARTYL METHIONYL GLUTAMINYL ASPARTYL ALDEHYDE; ACETYL-ASPARTYL-METHIONYL-GLUTAMINYL-ASPARTYL-ALDEHYDE; ANDROSTANE DERIVATIVE; CASP3 PROTEIN, HUMAN; CASPASE; DRUG DERIVATIVE; ENZYME INHIBITOR; N ACETYLSPHINGOSINE; N-ACETYLSPHINGOSINE; OLIGOPEPTIDE; SPHINGOSINE;

APOPTOSIS; ARTICLE; CATALYSIS; CELL DAMAGE; CELL STRAIN HL 60; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PURIFICATION; ENZYME SUBUNIT; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; OXIDATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN SECRETION; CELL MEMBRANE POTENTIAL; DRUG ANTAGONISM; INTRACELLULAR MEMBRANE; LIPID METABOLISM; LIPID PEROXIDATION; METABOLISM; MITOCHONDRION; OXIDATION REDUCTION REACTION; PHYSIOLOGY;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANDROSTADIENES; APOPTOSIS; CASPASE 3; CASPASES; CATALASE; ENZYME ACTIVATION; ENZYME INHIBITORS; HL-60 CELLS; HUMANS; INSULIN-LIKE GROWTH FACTOR I; INTRACELLULAR MEMBRANES; LIPID METABOLISM; LIPID PEROXIDATION; MEMBRANE POTENTIALS; MITOCHONDRIA; OLIGOPEPTIDES; OXIDATION-REDUCTION; SPHINGOSINE;

EID: 85047682131     PISSN: 13509047     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cdd.4401019     Document Type: Article

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