Cloning of rat parkin cDNA and distribution of parkin in rat brain

Journal of Neurochemistry

Volumn 74, Issue 4, 2000, Pages 1773-1776

  Gu, Wen Jie ^a   Abbas, Nacer ^a   Lagunes, Martin Zarate ^a   Parent, André ^a   Pradier, Laurent ^b   Bohme, Georg A ^b   Agid, Yves ^a   Hirsch, Etienne C ^a   Raisman Vozari, Rita ^a   Brice, Alexis ^a  

^a PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^b SANOFI   (France)

Author keywords

Antibody; Autosomal recessive juvenile parkinsonism; cDNA cloning; Genetics; Parkinson's disease; Rat parkin

Indexed keywords

M PROTEIN; PARKIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL TISSUE; ARTICLE; DNA SEQUENCE; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PARKINSON DISEASE; PARKINSONISM; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RAT; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; TISSUE DISTRIBUTION;

ANIMALS; ANTIBODIES; BLOTTING, WESTERN; BRAIN CHEMISTRY; CLONING, MOLECULAR; DNA, COMPLEMENTARY; GENES, RECESSIVE; LIGASES; MOLECULAR SEQUENCE DATA; NEUROGLIA; NEURONS; PARKINSON DISEASE; PROTEINS; RATS; SEQUENCE HOMOLOGY, AMINO ACID; UBIQUITIN-PROTEIN LIGASES;

ANIMALIA;

EID: 17444433155     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2000.0741773.x     Document Type: Article

References (20)

1. Abbas N., Lucking C. B., Ricard S., Durr A., Bonifati V., De Michele G., Bouley S., Vaughan J. R., Gasser T., Marconi R., Broussolle E., Brefel-Courbon C., Harhangi B. S., Oostra B. A., Fabrizio E., Bohme G. A., Pradier L., Wood N. W., Filla A., Meco G., Denefle P., Agid Y., and Brice A. (1999) A wide variety of mutations in the parkin gene are responsible for autosomal recessive parkinsonism in Europe. French Parkinson's Disease Genetics Study Group and the European Consortium on Genetic Susceptibility in Parkinson's Disease. Hum. Mol. Genet. 8, 567-574.
2. El Mestikawy S., Riad M., Laporte A. M., Verge D., Daval G., Gozlan H., and Hamon M. (1990) Production of specific anti-rat 5-HT1A receptor antibodies in rabbits injected with a synthetic peptide. Neurosci. Lett. 118, 189-192.
3. Fearnley J. M. and Lees A. J. (1991) Ageing and Parkinson's disease: substantia nigra regional selectivity. Brain 114, 2283-2301.
4. Finley D. and Chau V. (1991) Ubiquitination. Annu. Rev. Cell Biol. 7, 25-69.
5. Hattori N., Kitada T., Matsumine H., Asakawa S., Yamamura Y., Yoshino H., Kobayashi T., Yokochi M., Wang M., Yoritaka A., Kondo T., Kuzuhara S., Nakamura S., Shimizu N., and Mizuno Y. (1998a) Molecular genetic analysis of a novel parkin gene in Japanese families with autosomal recessive juvenile parkinsonism: evidence for variable homozygous deletions in the parkin gene in affected individuals. Ann. Neurol. 44, 935-941.
6. Hattori N., Matsumine H., Asakawa S., Kitada T., Yoshino H., Elibol B., Brookes A. J., Yamamura Y., Kobayashi T., Wang M., Yoritaka A., Minoshima S., Shimizu N., and Mizuno Y. (1998b) Point mutations (Thr240Arg and Ala311Stop) in the parkin. Biochem. Biophys. Res. Commun. 249, 754-758.
7. Horowitz J. M., Myers J., Stachowiak M. K., and Torres G. (1999) Identification and distribution of parkin in rat brain. Neuroreport 10, 3393-3397.
8. Hughes A. J., Daniel S. E., Blankson S., and Lees A. J. (1993) A clinicopathologic study of 100 cases of Parkinson's disease. Arch. Neurol. 50, 140-148.
9. Hunot S., Dugas N., Faucheux B., Hartmann A., Tardieu M., Debre P., Agid Y., Dugas B., and Hirsch E. C. (1999) FcepsilonRII/CD23 is expressed in Parkinson's disease and induces, in vitro, production of nitric oxide and tumor necrosis factor-alpha in glial cells. J. Neurosci. 19, 3440-3447.
10. Kitada T., Asakawa S., Hattori N., Matsumine H., Yamamura Y., Minoshima S., Yokochi M., Mizuno Y., and Shimizu N. (1998) Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism. Nature 392, 605-608.
11. Kruger R., Vieira-Sacker A. M., Kuhn W., Muller T., Woitalla D., Schols L., Przuntek H., Epplen J. T., and Riess O. (1999) Analysis of the parkin deletion in sporadic and familial Parkinson's disease. J. Neural Transm. 106, 159-163.
12. Langston J. W., Ballard P., Tetrud J. W., and Irwin I. (1983) Chronic parkinsonism in humans due to a product of meperidine-analog synthesis. Science 219, 979-980.
13. Lucking C. B., Abbas N., Durr A., Bonitati V., Bonnet A. M., de Broucker T., De Michele G., Wood N. W., Agid Y., and Brice A. (1998) Homozygous deletions in parkin gene in European and North African families with autosomal recessive juvenile parkinsonism. The European Consortium on Genetic Susceptibility in Parkinson's Disease and the French Parkinson's Disease Genetics Study Group. Lancet 352, 1355-1356.
14. Morett E. and Bork P. (1999) A novel transactivation domain in parkin. Trends Biochem. Sci. 24, 229-231.
15. Moynihan T. P., Ardley H. C., Nuber U., Rose S. A., Jones P. F., Markham A. F., Scheffner M., and Robinson P. A. (1999) The ubiquitin-conjugating enzymes UbcH7 and UbcH8 interact with RING finger/IBR motif-containing domains of HHARI and H7-API. J. Biol. Chem. 274, 30963-30968.
16. Polymeropoulos M. H., Lavedan C., Leroy E., Ide S. E., Dehejia A., Dutra A., Pike B., Root H., Rubenstein J., Boyer R., Stenroos E. S., Chandrasekharappa S., Athanassiadou A., Papapetropoulos T., Johnson W. G., Lazzarini A. M., Duvoisin R. C., Di Iorio G., Golbe L. I., and Nussbaum R. L. (1997) Mutation in the alpha-synuclein gene identified in families with Parkinson's disease. Science 276, 2045-2047.
17. Semchuck K. M., Love E. J., and Lec R. G. (1992) Parkinson's disease and exposure to agricultural work and pesticide chemicals. Neurology 42, 13128-13135.
18. Shimura H., Hattori N., Kubo S., Yoshikawa M., Kitada T., Matsumine H., Asakawa S., Minoshima S., Yamamura Y., Shimizu N., and Mizuno Y. (1999) Immunohistochemical and subcellular localization of parkin protein: absence of protein in autosomal recessive juvenile parkinsonism patients. Ann. Neurol. 45, 668-672.
19. Stevanin G., Trottier Y., Cancel G., Durr A., David G., Didierjean O., Burk K., Imbert G., Saudou F., Abada-Bendib M., Gourfinkel-An I., Benomar A., Abbas N., Klockgether T., Grid D., Agid Y., Mandel J. L., and Brice A. (1996) Screening for proteins with polyglutamine expansions in autosomal dominant cerebellar ataxias. Hum. Mol. Genet. 5, 1887-1892.
20. Tokunaga C., Kuroda S., Tatematsu K., Nakagawa N., Ono Y., and Kikkawa U. (1998) Molecular cloning and characterization of a novel protein kinase C-interacting protein with structural motifs related to RBCC family proteins. Biochem. Biophys. Res. Commun. 244, 353-359.