Monitoring cell therapy using iron oxide MR contrast agents

Current Pharmaceutical Biotechnology

Volumn 5, Issue 6, 2004, Pages 567-584

  Bulte, Jeff W M ^a   Kraitchman, Dara L ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Iron oxide; MR contrast agent; Myelin; Myocardial infarction; Neurodegeneration; Progenitor cell; Stem cell

Indexed keywords

BETA GALACTOSIDASE; BETA GLUCURONIDASE; CARBON 11; CYCLOSPORIN; DENDRIMER; DESMIN; DIVINYLBENZENE; DOPAMINE 2 RECEPTOR; GADOLINIUM; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; GREEN FLUORESCENT PROTEIN; IRON OXIDE; LECTIN; LIPOFECTAMINE; LIPOSOME; MICROSPHERE; MONOCRYSTALLINE IRON OXIDE NANOPARTICLE; MYELIN; NUCLEAR MAGNETIC RESONANCE IMAGING AGENT; OLIGONUCLEOTIDE; POLYLYSINE; RACLOPRIDE; RECEPTOR ANTIBODY; RETINOIC ACID; STYRENE; SUPERFECT; SUPERPARAMAGNETIC IRON OXIDE; TRANSACTIVATOR PROTEIN; TRANSFERRIN RECEPTOR; ULTRASMALL SUPERPARAMAGNETIC IRON OXIDE; UNINDEXED DRUG;

ADOPTIVE IMMUNOTHERAPY; BIOCOMPATIBILITY; CELL LABELING; CELL POPULATION; CELL TRANSPLANTATION; CELLULAR DISTRIBUTION; CENTRAL NERVOUS SYSTEM DISEASE; DRUG CHOICE; DRUG COATING; DRUG FORMULATION; DRUG HALF LIFE; DRUG TRANSPORT; DRUG UPTAKE; FUTUROLOGY; GRAFT REJECTION; HEART INFARCTION; HUMAN; HUNTINGTON CHOREA; MUCOPOLYSACCHARIDOSIS; NON INVASIVE MEASUREMENT; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PARKINSON DISEASE; PATIENT MONITORING; PROCESS OPTIMIZATION; REVIEW; STEM CELL; TRANSFUSION;

ANIMALS; CELL COUNT; CONTRAST MEDIA; DRUG DELIVERY SYSTEMS; FERRIC COMPOUNDS; HUMANS; IMAGE INTERPRETATION, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; MAGNETICS; MOLECULAR BIOLOGY; MOLECULAR PROBE TECHNIQUES; MOLECULAR PROBES; PROGNOSIS; TISSUE THERAPY;

ANIMALIA;

EID: 10644286399     PISSN: 13892010     EISSN: None     Source Type: Journal    
DOI: 10.2174/1389201043376526     Document Type: Review

References (166)

1. Eriksson, P. S., Perfilieva, E., Bjork-Eriksson, T., Alborn, A. M., Nordborg, C., Peterson, D. A. and Gage, F. H. (1998) Nat. Med. 4, 1313-1317.
2. Johansson, C. B., Momma, S., Clarke, D. L., Risling, M., Lendahl, U. and Frisen, J. (1999) Cell 96, 25-34.
3. Giovanini, M. A., Reier, P. J., Eskin, T. A., Wirth, E. and Anderson, D. K. (1997) Exp. Neurol. 148, 523-543.
4. Wirth, E. D., 3rd, Reier, P. J., Fessler, R. G., Thompson, F. J., Uthman, B., Behrman, A., Beard, J., Vierck, C. J. and Anderson, D. K. (2001) J. Neurotrauma 18, 911-929.
5. McDonald, J. W., Liu, X. Z., Qu, Y., Liu, S., Mickey, S. K., Turetsky, D., Gottlieb, D. I. and Choi, D. W. (1999) Nat. Med. 5 1410-1412.
6. Ogawa, Y., Sawamoto, K., Miyata, T., Miyao, S., Watanabe, M., Nakamura, M., Bregman, B. S., Koike, M., Uchiyama, Y., Toyama, Y. and Okano, H. (2002) J. Neurosci. Res. 69, 925-933.
7. Teng, Y. D., Lavik, E. B., Qu, X., Park, K. I., Ourednik, J., Zurakowski, D., Langer, R. and Snyder, E. Y. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 3024-3029.
8. Rapalino, O., Lazarov-Spiegler, O., Agranov, E., Velan, G. J., Yoles, E., Fraidakis, M., Solomon, A., Gepstein, R., Katz, A., Belkin, M., Hadani, M. and Schwartz, M. (1998) Nat. Med. 4, 814-821.
9. Bjorklund, A. and Stenevi, U. (1979) Brain Res. 177 555-560.
10. Perlow, M. J., Freed, W. J., Hoffer, B. J., Seiger, A., Olson, L. and Wyatt, R. J. (1979) Science 204, 643-647.
11. Kordower, J. H., Freeman, T. B., Snow, B. J., Vingerhoets, F. J., Mufson, E. J., Sanberg, P. R., Hauser, R. A., Smith, D. A., Nauert, G. M., Perl, D. P. and et al. (1995) N. Engl. J. Med. 332 1118-1124.
12. Lindvall, O., Brundin, P., Widner, H., Rehncrona, S., Gustavii, B., Frackowiak, R., Leenders, K. L., Sawle, G., Rothwell, J. C., Marsden, C. D. and et al. (1990) Science 247, 574-577.
13. Widner, H., Tetrud, J., Rehncrona, S., Snow, B., Brundin, P., Gustavii, B., Bjorklund, A., Lindvall, O. and Langston, J. W. (1992) N. Engl. J. Med. 327, 1556-1563.
14. Piccini, P., Brooks, D. J., Bjorklund, A., Gunn, R. N., Grasby, P. M., Rimoldi, O., Brundin, P., Hagell, P., Rehncrona, S., Widner, H. and Lindvall, O. (1999) Nat. Neurosci. 2, 1137-1140.
15. Schumacher, J. M., Ellias, S. A., Palmer, E. P., Kott, H. S., Dinsmore, J., Dempsey, P. K., Fischman, A. J., Thomas, C., Feldman, R. G., Kassissieh, S., Raineri, R., Manhart, C., Penney, D., Fink, J. S. and Isacson, O. (2000) Neurology 54, 1042-1050.
16. Liker, M. A., Petzinger, G. M., Nixon, K., McNeill, T. and Jakowec, M. W. (2003) Brain Res. 971, 168-177.
17. Savitt, J. M., Bulte, J. W. M., Dawson, V. L., Gearhart, J. D., Shamblott, M. J., Hakumaki, J. M., Axelman, J. and Dawson, T. M. (2002) Movement Disord 17, P694 Suppl. 695.
18. Kim, J. H., Auerbach, J. M., Rodriguez-Gomez, J. A., Velasco, I., Gavin, D., Lumelsky, N., Lee, S. H., Nguyen, J., Sanchez-Pernaute, R., Bankiewicz, K. and McKay, R. (2002) Nature 418, 50-56.
19. Bjorklund, L. M., Sanchez-Pernaute, R., Chung, S., Andersson, T., Chen, I. Y., McNaught, K. S., Brownell, A. L., Jenkins, B. G., Wahlestedt, C., Kim, K. S. and Isacson, O. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 2344-2349.
20. Shingo, T., Date, I., Yoshida, H. and Ohmoto, T. (2002) J. Neurosci. Res. 69, 946-954.
21. Ostenfeld, T., Tai, Y. T., Martin, P., Deglon, N., Aebischer, P. and Svendsen, C. N. (2002) J. Neurosci. Res. 69, 955-965.
22. Chang, A., Tourtellotte, W. W., Rudick, R. and Trapp, B. D. (2002) N. Engl. J. Med. 346, 165-173.
23. Wolswijk, G. (2002) Brain 125, 338-349.
24. Blakemore, W. F. and Franklin, R. J. (1991) Trends Neurosci. 14, 323-327.
25. Duncan, I. D. (1996) Neuropathol. Appl. Neurobiol. 22, 87-100.
26. Utzschneider, D. A., Archer, D. R., Kocsis, J. D., Waxman, S. G. and Duncan, I. D. (1994) Proc. Natl. Acad. Sci. U. S. A. 91 53-57.
27. Kohama, I., Lankford, K. L., Preiningerova, J., White, F. A., Vollmer, T. L. and Kocsis, J. D. (2001) J. Neurosci. 21, 944-950.
28. Akiyama, Y., Honmou, O., Kato, T., Uede, T., Hashi, K. and Kocsis, J. D. (2001) Exp. Neurol. 167, 27-39.
29. Imaizumi, T., Lankford, K. L., Burton, W. V., Fodor, W. L. and Kocsis, J. D. (2000) Nat. Biotechnol. 18, 949-953.
30. Archer, D. R., Cuddon, P. A., Lipsitz, D. and Duncan, I. D. (1997) Nat. Med. 3, 54-59.
31. Brustle, O., Jones, K. N., Learish, R. D., Karram, K., Choudhary, K., Wiestler, O. D., Duncan, I. D. and McKay, R. D. (1999) Science 285, 754-756.
32. Yandava, B. D., Billinghurst, L. L. and Snyder, E. Y. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 7029-7034.
33. Isacson, O., Brundin, P., Kelly, P. A., Gage, F. H. and Bjorklund, A. (1984) Nature 311, 458-460.
34. Isacson, O., Dunnett, S. B. and Bjorklund, A. (1986) Proc. Natl. Acad. Sci. U. S. A. 83, 2728-2732.
35. Palfi, S., Conde, F., Riche, D., Brouillet, E., Dautry, C., Mittoux, V., Chibois, A., Peschanski, M. and Hantraye, P. (1998) Nat. Med. 4, 963-966.
36. Borlongan, C. V., Tajima, Y., Trojanowski, J. Q., Lee, V. M. and Sanberg, P. R. (1998) Exp. Neurol. 149, 310-321.
37. Kleppner, S. A., Robinson, K. A., Trojanowski, J. Q. and Lee, V. M. (1995) J. Comp. Neurol. 357, 618-632.
38. Trojanowski, J. Q., Mantione, J. R., Lee, J. H., Seid, D. P., You, T., Inge, L. J. and Lee, V. M. (1993) Exp. Neurol. 122, 283-294.
39. Kondziolka, D., Wechsler, L., Goldstein, S., Meltzer, C., Thulborn, K. R., Gebel, J., Jannetta, P., DeCesare, S., Elder, E. M., McGrogan, M., Reitman, M. A. and Bynum, L. (2000) Neurology 55 565-569.
40. Snyder, E. Y., Taylor, R. M. and Wolfe, J. H. (1995) Nature 374, 367-370.
41. Lacorazza, H. D., Flax, J. D., Snyder, E. Y. and Jendoubi, M. (1996) Nat. Med. 2, 424-429.
42. Thomson, J. A., Itskovitz-Eldor, J., Shapiro, S. S., Waknitz, M. A., Swiergiel, J. J., Marshall, V. S. and Jones, J. M. (1998) Science 282, 1145-1147.
43. Shamblott, M. J., Axelman, J., Wang, S., Bugg, E. M., Littlefield, J. W., Donovan, P. J., Blumenthal, P. D., Huggins, G. R. and Gearhart, J. D. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 13726-13731.
44. Reubinoff, B. E., Itsykson, P., Turetsky, T., Pera, M. F., Reinhartz, E., Itzik, A. and Ben-Hur, T. (2001) Nat. Biotechnol. 19, 1134-1140.
45. Zhang, S. C., Wernig, M., Duncan, I. D., Brustle, O. and Thomson, J. A. (2001) Nat. Biotechnol. 19, 1129-1133.
46. Heart Disease and Stroke Statistics - 2003 Update. (American Heart Association, Dallas, TX, 2003).
47. Miake, J., Marban, E. and Nuss, H. B. (2002) Nature 419, 132-133.
48. Chiu, R. C., Zibaitis, A. and Koao, R. L. (1995) Ann. Thorac. Surg. 60, 12-18.
49. Koh, G. Y., Klug, M. G., Soonpaa, M. H. and Field, L. J. (1993) J. Clin. Invest. 92, 1548-1554.
50. Marelli, D., Desrosiers, C., El-Alfy, M., Kao, R. L. and Chiu, R. C. J. (1992) Cell Transplant. 1, 383-390.
51. Murry, C. E., Wiseman, R. W., Schwartz, S. M. and Hauschka, S. D. (1996) J. Clin. Invest. 98, 2512-2523.
52. Robinson, S. W., Cho, P. C., Levitsky, H. I., Olson, J. L., Hruban, R. H., Acker, M. A. and Kessler, P. D. (1996) Cell Transplant. 5, 77-91.
53. Dib, N., Diethrich, E. B., Campbell, A., Goodwin, N., Robinson, B., Gilbert, J., Hobohm, D. W. and Taylor, D. A. (2002) J. Endovasc. Ther. 9, 313-319.
54. Taylor, D. A., Atkins, B. Z., Hungspreugs, P., Jones, T. R., Reedy, M. C., Hutcheson, K. A., Glower, D. D. and Kraus, W. E. (1998) Nat. Med. 4, 929-933.
55. Leobon, B., Garcin, I., Menasche, P., Vilquin, J. T., Audinat, E. and S., C. (2003) Proc. Natl. Acad. Sci. U. S. A. 100, 7808-7811.
56. Atkins, B. Z., Hueman, M. T., Meuchel, J. M., Cottman, M. J., Hutcheson, K. A. and Taylor, D. A. (1999) J. Heart Lung Transpl. 18, 1173-1180.
57. Jain, M., DerSimonian, H., Brenner, D. A., Ngoy, S., Teller, P., Edge, A. S., Zawadzka, A., Wetzel, K., Sawyer, D. B., Colucci, W. S., Apstein, C. S. and Liao, R. (2001) Circulation 103, 1920-1927.
58. Pouzet, B., Vilquin, J. T., Hagege, A. A., Scorsin, M., Messas, E., Fiszman, M., Schwartz, K. and Menasche, P. (2000) Circulation 102, III210-III215.
59. Rajnoch, C., Chachques, J. C., Berrebi, A., Bruneval, P., Benoit, M. O. and Carpentier, A. (2001) J. Thorac. Cardiovasc. Surg. 121, 871-878.
60. Menasche, P., Hagege, A. A., Vilquin, J. T., Desnos, M., Abergel, E., Pouzet, B., Bel, A., Sarateariu, S., Scorsin, M., Schwartz, K., Bruneval, P., Benbunan, M., Marolleau, J. P. and Duboc, D. (2003) J. Am. Coll. Cardiol. 41, 1078-1083.
61. Li, R. K., Jia, Z. Q., Weisel, R. D., Mickle, D. A., Zhang, J., Mohabeer, M. K., Rao, V. and Ivanov, J. (1996) Ann. Thorac. Surg. 62, 654-661.
62. Li, R. K., Mickle, D. A., Weisel, R. D., Rao, V. and Jia, Z. Q. (2001) Ann. Thorac. Surg. 72, 1957-1963.
63. Sakai, T., Li, R. K., Weisel, R. D., Mickle, D. A., Jia, Z. Q., Tomita, S., Kim, E. J. and Yau, T. M. (1999) J. Thorac. Cardiovasc. Surg. 118, 715-724.
64. Li, R. K., Jia, Z. Q., Weisel, R. D., Merante, F. and Mickle, D. A. (1999) J. Mol. Cell Cardiol. 31, 513-522.
65. Li, R. K., Weisel, R. D., Mickle, D. A., Jia, Z. Q., Kim, E. J., Sakai, T., Tomita, S., Schwartz, L., Iwanochko, M., Husain, M., Cusimano, R. J., Burns, R. J. and Yau, T. M. (2000) J. Thorac. Cardiovasc. Surg. 119, 62-68.
66. Sakai, T., Li, R. K., Weisel, R. D., Mickle, D. A., Kim, E. J., Tomita, S., Jia, Z. Q. and Yau, T. M. (1999) Ann. Thorac. Surg. 68, 2074-2080.
67. Deb, A., Wang, S., Skelding, K. A., Miller, D., Simper, D. and Caplice, N. M. (2003) Circulation 107, 1247-1249.
68. Toma, C., Pittenger, M. F., Cahill, K. S., Byrne, B. J. and Kessler, P. D. (2002) Circulation 105, 93-98.
69. Makino, S., Fukuda, K., Miyoshi, S., Konishi, F., Kodama, H., Pan, J., Sano, M., Takahashi, T., Hori, S., Abe, H., Hata, J., Umezawa, A. and Ogawa, S. (1999) J. Clin. Invest. 103, 697-705.
70. Tomita, S., Li, R. K., Weisel, R. D., Mickle, D. A., Kim, E. J., Sakai, T. and Jia, Z. Q. (1999) Circulation 100, II247-256.
71. Orlic, D., Kajstura, J., Chimenti, S., Jakoniuk, I., Anderson, S. M., Li, B., Pickel, J., McKay, R., Nadal-Ginard, B., Bodine, D. M., Leri, A. and Anversa, P. (2001) Nature 410, 701-705.
72. Shake, J. G., Gruber, P. J., Baumgartner, W. A., Senechal, G., Meyers, J., Redmond, J. M., Pittenger, M. F. and Martin, B. J. (2002) Ann. Thorac. Surg. 73, 1919-1925; discussion 1926.
73. Jackson, K. A., Majka, S. M., Wang, H., Pocius, J., Hartley, C. J., Majesky, M. W., Entman, M. L., Michael, L. H., Hirschi, K. K. and Goodell, M. A. (2001) J. Clin. Invest. 107, 1395-1402.
74. Kocher, A. A., Schuster, M. D., Szabolcs, M. J., Takuma, S., Burkhoff, D., Wang, J., Homma, S., Edwards, N. M. and Itescu, S. (2001) Nat. Med. 7, 430-436.
75. Wang, J. S., Shum-Tim, D., Galipeau, J., Chedrawy, E., Eliopoulos, N. and Chiu, R. C. (2000) J. Thorac. Cardiovasc. Surg. 120, 999-1005.
76. Tomita, S., Mickle, D. A., Weisel, R. D., Zhi-Qiang, J., Tumiati, L. C., Allidina, Y., Liu, P. and Li, R. K. (2002) J. Thorac. Cardiovasc. Surg. 123, 1132-1140.
77. Yau, T. M., Tomita, S., Weisel, R. D., Jia, Z. Q., Tumiati, L. C., Mickle, D. A. and Li, R. K. (2003) Ann. Thorac. Surg. 75 169-176; discussion 176-167.
78. Barbash, I. M., Chouraqui, P., Baron, J., Feinberg, M. S., Etzion, S., Tessone, A., Miller, L., Guetta, E., Zipori, D., Kedes, L. H., Kloner, R. A. and Leor, J. (2003) Circulation 108, 863-868.
79. Wang, J. S., Shum-Tim, D., Chedrawy, E. and Chiu, R. C. (2001) J. Thorac. Cardiovasc. Surg. 122, 699-705.
80. Strauer, B. E., Brehm, M., Zeus, T., Köstering, M., Hernandez, A., Sorg, R. V., Kögler, G. and Wernet, P. (2002) Circulation 106, 1913-1918.
81. Gao, J., Dennis, J. E., Muzic, R. F., Lundberg, M. and Caplan, A. I. (2001) Cell Tissues Organs 169, 12-20.
82. Bulte, J. W. M., Duncan, I. D. and Frank, J. A. (2002) J. Cereb. Blood Flow Metab. 22, 899-907.
83. Bulte, J. W. M., Mori, S. and van Zijl, P. C. M. (2002) Trends in Biotechnol. 20, S24-S28.
84. Weissleder, R., Stark, D. D., Engelstad, B. L., Bacon, B. R., Compton, C. C., White, D. L., Jacobs, P. and Lewis, J. (1989) AJR. Am. J. Roentgenol. 152, 167-173.
85. Modo, M., Cash, D., Mellodew, K., Williams, S. C., Fraser, S. E., Meade, T. J., Price, J. and Hodges, H. (2002) Neuroimage 17 803-811.
86. Stark, D. D., Weissleder, R., Elizondo, G., Hahn, P. F., Saini, S., Todd, L. E., Wittenberg, J. and Ferrucci, J. T. (1988) Radiology 168, 297-301.
87. Weissleder, R. (1994) Radiology 193, 593-595.
88. Harisinghani, M. G., Barentsz, J., Hahn, P. F., Deserno, W. M., Tabatabaei, S., van de Kaa, C. H. de la Rosette, J. and Weissleder, R. (2003) N. Engl. J. Med. 348, 2491-2499.
89. Weissleder, R., Elizondo, G., Wittenberg, J., Lee, A. S., Josephson, L. and Brady, T. J. (1990) Radiology 175, 494-498.
90. Weissleder, R., Heautot, J. F., Schaffer, B. K., Nossiff, N., Papisov, M. I., Bogdanov, A., Jr. and Brady, T. J. (1994) Radiology 191, 225-230.
91. Seneterre, E., Weissleder, R., Jaramillo, D., Reimer, P., Lee, A. S., Brady, T. J. and Wittenberg, J. (1991) Radiology 179 529-533.
92. Xu, S., Jordan, E. K., Brocke, S., Butte, J. W., Quigley, L., Tresser, N., Ostuni, J. L., Yang, Y., McFarland, H. F. and Frank, J. A. (1998) J. Neurosci. Res. 52, 549-558.
93. Dousset, V., Ballarino, L., Delalande, C., Coussemacq, M., Canioni, P., Petry, K. G. and Caille, J. M. (1999) AJNR. Am. J. Neuroradiol. 20, 223-227.
94. Dousset, V., Delalande, C., Ballarino, L., Quesson, B., Seilhan, D., Coussemacq, M., Thiaudiere, E., Brochet, B., Canioni, P. and Caille, J. M. (1999) Magn. Reson. Med. 41, 329-333.
95. Rausch, M., Hiestand, P., Baumann, D., Cannet, C. and Rudin, M. (2003) Magn. Reson. Med. 50, 309-314.
96. Hauger, O., Delalande, C., Trillaud, H., Deminiere, C., Quesson, B., Kahn, H., Cambar, J., Combe, C. and Grenier, N. (1999) Magn. Reson. Med. 41, 156-162.
97. Hauger, O., Delalande, C., Deminiere, C., Fouqueray, B., Ohayon, C., Garcia, S., Trillaud, H., Combe, C. and Grenier, N. (2000) Radiology 217, 819-826.
98. Jo, S. K., Hu, X., Kobayashi, H., Lizak, M., Miyaji, T., Koretsky, A. and Star, R. A. (2003) Kidney Int. 64, 43-51.
99. Beckmann, N., Falk, R., Zurbrugg, S., Dawson, J. and Engelhardt, P. (2003) Magn. Reson. Med. 49, 1047-1055.
100. Beckmann, N., Cannet, C., Fringeli-Tanner, M., Baumann, D., Pally, C., Bruns, C., Zerwes, H. G., Andriambeloson, E. and Bigaud, M. (2003) Magn. Reson. Med. 49, 459-467.
101. Zhang, Y., Dodd, S. J., Hendrich, K. S., Williams, M. and Ho, C. (2000) Kidney Int. 58, 1300-1310.
102. Kanno, S., Lee, P. C., Dodd, S. J., Williams, M., Griffith, B. P. and Ho, C. (2000) J. Thorac. Cardiovasc. Surg. 120, 923-934.
103. Kanno, S., Wu, Y. J., Lee, P. C., Dodd, S. J., Williams, M., Griffith, B. P. and Ho, C. (2001) Circulation 104, 934-938.
104. Sipe, J. C., Filippi, M., Martino, G., Furlan, R., Rocca, M. A., Rovaris, M., Bergami, A., Zyroff, J., Scotti, G. and Comi, G. (1999) Magn. Reson. Imaging 17, 1521-1523.
105. Yeh, T. C., Zhang, W., Ildstad, S. T. and Ho, C. (1993) Magn. Reson. Med. 30, 617-625.
106. Moore, A., Weissleder, R. and Bogdanov, A., Jr. (1997) J. Magn. Reson. Imaging 7, 1140-1145.
107. Weissleder, R., Cheng, H. C., Bogdanova, A. and Bogdanov, A., Jr. (1997) J. Magn. Reson. Imaging 7, 258-263.
108. Franklin, R. J., Blaschuk, K. L., Bearchell, M. C., Prestoz, L. L., Setzu, A., Brindle, K. M. and ffrench-Constant, C. (1999) Neuroreport 10, 3961-3965.
109. Bulte, J. W. M., Ma, L. D., Magin, R. L., Kamman, R. L., Hulstaert, C. E., Go, K. G., The, T. H. and de Leij, L. (1993) Magn. Reson. Med. 29, 32-37.
110. Bulte, J. W. M., Laughlin, P. G., Jordan, E. K., Tran, V. A., Vymazal, J. and Frank, J. A. (1996) Acad. Radiol. 3 Suppl 2, S301-303.
111. Josephson, L., Tung, C. H., Moore, A. and Weissleder, R. (1999) Bioconjug. Chem. 10, 186-191.
112. Lewin, M., Carlesso, N., Tung, C. H., Tang, X. W., Cory, D., Scadden, D. T. and Weissleder, R. (2000) Nat. Biotechnol. 18, 410-414.
113. Dodd, C. H., Hsu, H. C., Chu, W. J., Yang, P., Zhang, H. G., Mountz, J. D., Jr., Zinn, K., Forder, J., Josephson, L., Weissleder, R., Mountz, J. M. and Mountz, J. D. (2001) J. Immunol. Methods 256 89-105.
114. Zhao, M., Kircher, M. F., Josephson, L. and Weissleder, R. (2002) Bioconjug. Chem. 13, 840-844.
115. Jefferies, W. A., Brandon, M. R., Hunt, S. V., Williams, A. F., Gatter, K. C. and Mason, D. Y. (1984) Nature 312, 162-163.
116. Bulte, J. W. M., Zhang, S., van Gelderen, P., Herynek, V., Jordan, E. K., Duncan, I. D. and Frank, J. A. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 15256-15261.
117. Bulte, J. W. M., Ben-Hur, T., Miller, B. R., Mizrachi-Kol, R., Einstein, O., Reinhartz, E., Zywicke, H. A., Douglas, T. and Frank, J. A. (2003) Magn. Reson. Med. 50, 201-205.
118. Moore, A., Josephson, L., Bhorade, R., Basilion, J. P. and Weissleder, R. (2001) Radiology 221, 244-250.
119. Ahrens, E. T., Feili-Hariri, M., Xu, H., Genove, G. and Morel, P. A. (2003) Magn. Reson. Med. 49, 1006-1013.
120. Bulte, J. W. M., Douglas, T., Witwer, B., Zhang, S. C., Strable, E., Lewis, B. K., Zywicke, H., Miller, B., van Gelderen, P., Moskowitz, B. M., Duncan, I. D. and Frank, J. A. (2001) Nat. Biotechnol. 19, 1141-1147.
121. Strable, E., Bulte, J. W. M., Moskowitz, B. M., Vivekanandan, K., Allen, M. and Douglas, T. (2001) Chem. Mater. 13, 2201-2209.
122. Bryant Jr., L. H. and Bulte, J. W. M. in Focus on Biotechnology, vol. 7: Physics and chemistry basis of biotechnology (eds. de Cuyper, M. & Bulte, J. W. M.) (Kluwer Academic Publishers, Dordrecht, 2001).
123. Kukowska-Latallo, J. F., Bielinska, A. U., Johnson, J., Spindler, R., Tomalia, D. A. and Baker, J. R., Jr. (1996) Proc, Natl. Acad. Sci. U. S. A. 93, 4897-4902.
124. Tang, M. X., Redemann, C. T. and Szoka, F. C., Jr. (1996) Bioconjug. Chem. 7, 703-714.
125. Zhang, Z.-Y. and Smith, B. D. (2000) Bioconjug. Chem. 11, 805-814.
126. Bulte, J. W. M., Douglas, T., van Gelderen, P., Lewis, B. K. and Frank, J. A. (2001) Proc. Intl. Soc. Magn. Reson. Med. 9, 52.
127. Bulte, J. W. M., Lu, J., Zywicke, H., van Gelderen, P., Douglas, T., McDonald, J. W. and Frank, J. A. (2001) Proc. Intl. Soc. Magn. Reson. Med. 9, 130.
128. Walter, G. A., Cahill, K. S., Huard, J., Feng, H., Douglas, T., Sweeney, H. L. and Bulte, J. W. M. (in press) Magn. Reson. Med.
129. Billotey, C., Wilhelm, C., Devaud, M., Bacri, J. C., Bittoun, J. and Gazeau, F. (2003) Magn. Reson. Med. 49, 646-654.
130. Wilhelm, C., Billotey, C., Roger, J., Pons, J. N., Bacri, J. C. and Gazeau, F. (2003) Biomaterials 24, 1001-1011.
131. Wilhelm, C., Gazeau, F., Roger, J., Pons, J. N. and Bacri, J. C. (2002) Langmuir 18, 8148-8155.
132. Wilhelm, C., Cebers, A., Bacri, J. C. and Gazeau, F. (2003) Eur. Biophys. J.
133. Frank, J. A., Miller, B. R., Arbab, A. S., Zywicke, H. A., Jordan, E. K., Lewis, B. K., Bryant, L. H., Jr. and Bulte, J. W. (2003) Radiology 228, 480-487.
134. Frank, J. A., Zywicke, H., Jordan, E. K., Mitchell, J., Lewis, B. K., Miller, B., Bryant, L. H., Jr. and Bulte, J. W. M. (2002) Acad. Radiol. 9 Suppl. 2, S484-487.
135. Hoehn, M., Kustermann, E., Blunk, J., Wiedermann, D., Trapp, T., Wecker, S., Focking, M., Arnold, H., Hescheler, J., Fleischmann, B. K., Schwindt, W. and Buhrle, C. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 16267-16272.
136. Kalish, H., Arbab, A. S., Miller, B. R., Lewis, B. K., Zywicke, H. A., Bulte, J. W. M., Bryant Jr., L. H. and Frank, J. A. (2003) Magn. Reson. Med. 50, 275-282.
137. Kraitchman, D. L., Heldman, A. W., Atalar, E., Amado, L. C., Martin, B. J., Pittenger, M. F., Hare, J. M. and Bulte, J. W. M. (2003) Circulation 107, 2290-2293.
138. Kraitchman, D. L., Karmarkar, P., Amado, L. C., Atalar, E., Hofmann, L. V., Heldman, A. W., Martin, B. J., Pittenger, M. F. and Bulte, J. W. M. (2003) Proc. Intl. Soc. Mag. Reson. Med. 11, 360.
139. Anderson, S. A., Shukaliak-Quandt, J., Jordan, E. K., Arbab, A. S., Martin, R., McFarland, H. F. and Frank, J. A. (2003) Proc. Intl. Soc. Mag. Reson. Med. 11, 763.
140. Cahill, K. S., Silver, X., Gaidosh, G., Byrne, B. J. and Walter, G. A. (2003) Proc. Intl. Soc. Mag. Reson. Med. 11, 368.
141. Zhang, R. L., Zhang, L., Zhang, Z. G., Morris, D., Jiang, Q., Wang, L., Zhang, L. J. and Chopp, M. (2003) Neuroscience 116, 373-382.
142. Zhang, Z. G., Jiang, Q., Zhang, R., Zhang, L., Wang, L., Arniego, P., Ho, K. L. and Chopp, M. (2003) Ann. Neurol. 53, 259-263.
143. Dick, A. J., Guttman, M. A., Raman, V. K., Peters, D. C., Hill, J. M., Pessanha, B. S., Scott, G., Smith, S., McVeigh, E. R. and Lederman, R. J. (2003) Proc. Intl. Soc. Mag. Reson. Med. 11, 365.
144. Hill, J. M., Dick, A. J., Raman, V. K., Thompson, R. B., Pessanha, B. S., yu, Z., Hinds, A., Varney, T. R., Dunbar, C. E., McVeigh, E. R. and Lederman, R. J. (2003) Proc. Intl. Soc. Mag. Reson. Med. 11, 361.
145. Sorger, J. M., Despres, D., Schimel, D., McVeigh, E. R. and Hill, J. M. (2003) Proc. Intl. Soc. Mag. Reson. Med. 11, 364.
146. Hinds, K. A., Hill, J. M., Shapiro, E. M., Laukkanen, M. O., Silva, A. C., Combs, C. A., Varney, T. R., Balaban, R. S., Koretsky, A. P. and Dunbar, C. E. (2003) Blood 102, 867-872.
147. Dodd, S. J., Williams, M., Suhan, J. P., Williams, D. S., Koretsky, A. P. and Ho, C. (1999) Biophys. J. 76, 103-109.
148. Heyn, C., Bowen, C. V., Rutt, B. K. and Gareau, P. J. (2003) Proc. Intl. Soc. Mag. Reson. Med. 11, 805.
149. Norman, A. B., Thomas, S. R., Pratt, R. G., Lu, S. Y. and Norgren, R. B. (1992) Brain Res. 594, 279-283.
150. Hawrylak, N., Ghosh, P., Broadus, J., Schlueter, C., Greenough, W. T. and Lauterbur, P. C. (1993) Exp. Neurol. 121 181-192.
151. Yeh, T. C., Zhang, W., Ildstad, S. T. and Ho, C. (1995) Magn. Reson. Med. 33, 200-208.
152. Schoepf, U., Marecos, E. M., Melder, R. J., Jain, R. K. and Weissleder, R. (1998) Biotechniques 24, 642-646, 648-651.
153. Beuf, O., Janier, M., Asport, C., Thivolet, C. and Billotey, C. (2003) Proc. Intl. Soc. Mag. Reson. Med. 11, 828.
154. Moore, A., Sun, P. Z., Cory, D., Hogemann, D., Weissleder, R. and Lipes, M. A. (2002) Magn. Reson. Med. 47, 751-758.
155. Hakumaki, J. M., Savitt, J. M., Gearhart, J. D., Dawson, T. M., Dawson, V. L. and Bulte, J. W. M. (2001) Dev. Brain Res, 132 A43-44.
156. Turnbull, D. H., Wadghiri, Y. Z., Josephson, L. and Wichterle, H. (2001) Proc Intl Soc Magn Reson Med 9, 359.
157. Jendelova, P., Herynek, V., deCroos, J., Glogarova, K., Andersson B, Hajek, M. and Sykova, E. (in press) Magn. Reson. Med.
158. Ben-Hur, T., Einstein, O., Mizrachi-Kol, R., Ben-Menachem, O., Reinhartz, E., Karussis, D. and Abramsky, O. (2003) Glia 41 73-80.
159. Hill, J. M., Dick, A. J., Raman, V. K., Thompson, R. B., Yu, Z. X., Hinds, K. A., Pessanha, B. S., Guttman, M. A., Varney, T. R., Martin, B. J., Dunbar, C. E., McVeigh, E. R. and Lederman, R. J. (2003) Circulation 11, 11.
160. Kraitchman, D. L., Karmarkar, P., Amado, L. C., Atalar, E., Hofmann, L. V., Heldman, A. W., Martin, B. J., Pittenger, M. F. and Bulte, J. W. M. (2003) Proc. Intl. Soc. Mag. Reson. Med. 11, 360.
161. Hinds, K. A., Hill, J. M., Shapiro, E. M., Laukkanen, M. O., Silva, A. C., Combs, C. A., Varney T. R., Balaban, R. S., Koretsky, A. P. and Dunbar, C. E. (2003) Blood 102, 867-872.
162. Kraitchman, D. L., Heldman, A. W., Atalat, E., Amado, L., Martin, B. J., Pittenger, M. F., Hare, J. M. and Bulte, J. (2003) Circulation 107, 2290-2293.
163. Simonetti, O., Kim, R., Fieno, D. and et al. (2001) Radiology 218, 215-223.
164. Karmarkar, P., Atalar, E., Hofmann, L. and Kraitchman, D. (2003) Proc. Intl. Soc. Mag. Reson. Med. 11, 311.
165. Lederman, R. J., Guttman, M. A., Peters, D. C., Thompson, R. B., Sorger, J. M., Dick, A. J., Raman, V. K. and McVeigh, E. R. (2002) Circulation 105, 1282-1284.
166. Bowen, C. V., Zhang, X., Saab, G., Gareau, P. J. and Rutt, B. K. (2002) Magn. Reson. Med. 48, 52-61.