In vivo macrophage activity imaging in the central nervous system detected by magnetic resonance

Magnetic Resonance in Medicine

Volumn 41, Issue 2, 1999, Pages 329-333

  Dousset, Vincent ^a   Delalande, Christophe ^b   Ballarino, Lucrecia ^a   Quesson, Bruno ^b   Seilhan, Danielle ^c   Coussemacq, Monique ^a   Thiaudiére, Eric ^b   Brochet, Bruno ^a   Canioni, Paul ^b   Caillé, Jean Marie ^a  

^a UNIVERSITÉ DE BORDEAUX   (France)

^b CNRS   (France)

^c PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

Author keywords

Allergic; Contrast agents; Encephalomyelitis; Macrophages; Magnetic resonance imaging (MRI)

Indexed keywords

CYTOLOGY; IRON OXIDES; MACROPHAGES; MAGNETIC SUSCEPTIBILITY; MAGNETISM; NEUROPHYSIOLOGY; RESONANCE;

ALLERGIC; CENTRAL NERVOUS SYSTEMS; CONTRAST AGENT; ENCEPHALOMYELITIS; EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS; INTRAVENOUS INJECTIONS; MONONUCLEAR PHAGOCYTES; MORPHOLOGICAL ASPECTS;

MAGNETIC RESONANCE IMAGING;

IRON; ULTRASMALL SUPERPARAMAGNETIC IRON OXIDE;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; ELECTRON MICROSCOPY; FEMALE; IN VIVO STUDY; MACROPHAGE FUNCTION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; RAT;

EID: 0032965736     PISSN: 07403194     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1522-2594(199902)41:2<329::AID-MRM17>3.0.CO;2-Z     Document Type: Article

References (19)

1. Weissleder R, Elizondo G, Wittenberg J, Lee AS, Josephson L, Brady TJ. Ultrasmall superparamagnetic iron oxide: characterization of a new class contrast agents for MR imaging. Radiology 1990;175:494-498.
2. Weissleder R, Cheng H-G, Bogdanova A, Bogdanov A Jr. Magnetically labeled cells can be detected by MR imaging. J Magn Reson Imaging 1997;7:258-263.
3. Anzai Y, Blackwell KE, Hirschowitz SL, Rogers JW, Sato Y, Yuh WTC, Runge VM, Morris MR, McLachan SJ, Lufkin RH. Initial clinical experience with dextran-coated superparamagnetic iron oxide for detection of lymph node metastases in patients with head and neck cancer. Radiology 1994;192:709-715.
4. Yeh T, Zhang W, Ildstad ST, Ho G. Intracellular labeling of T-cells with superparamagnetic contrast agents. Magn Reson Med 1993;30:617-625.
5. Zimmer C, Weissleder R, Poss K, Bogdanova A Jr, Carter Wright S, Scott Enochs W. MR imaging of phagocytosis in experimental gliomas. Radiology 1995;197:533-538.
6. Bulte JWM, Ma LD, Magin RL, Kamman RL, Hulstaert CE, Go KG, The TH, de Leij L. Selective MR imaging of labeled human peripheral blood mononuclear cells by liposome mediated incorporation of dextranmagnetite particles. Magn Reson Med 1993;29:32-37.
7. Fedoroff S. In: Kettermann H, Ransom BR, editors. Neuroglia. Eds.), Oxford: Oxford University Press; 1995. p 162.
8. Lassmann H, Schmied M, Vass K, Hickey WF. Bone marrow derived elements and resident microglia in brain inflammation. Glia 1993;7: 19-24.
9. Flaris NA, Densmore TL, Molleston MC, Hickey WF. Characterization of microglia and macrophages in the central nervous system of rats: definition of the differential expression of molecules using standard and novel monoclonal antibodies in normal CNS and in four models of parenchymal reaction. Glia 1993;7:34-40.
10. Baner J, Huitinga I, Zhao W, Lassmann H, Hickey WF, Dijkstra CD. The role of macrophages, perivascular cells, and microglia cells in the pathogenesis of experimental autoimmune encephalomyelilis. Glia 1995;15:437-446.
11. Raine RC. Multiple sclerosis: immune system molecule expression in the central nervous system. J Neuropathol Exp Neurol 1994;53:328-337.
12. Dubois-Dalcq M, Altmeyer R, Chiron M, Wilt S, HIV interactions with cells of the nervous system. Curr Opin Neurobiol 1995;5:647-655.
13. Villaroya H, Violleau K, Ben Younes-Chennonfi A, Baumann N. Myelin-induced experimental allergic encephalomyelitis in Lewis rats: tumor necrosis factor alpha levels in serum and cerebrospinal fluid immunohistochemical expression in glial cells and macrophages of optic nerve and spinal cord. J Neuroimmunol 1996;64:55-61.
14. Rinner WA, Bauer J, Schmidts M, Lassmann H, Hickey WF. Resident microglia and hematogenous macrophages as phagocytes in adoptively transferred experimental antoimmune encephalomyelitis: an investigation using rat radiation bone marrow chimeras. Glia 1995;14:257-266.
15. Hickey WF, Vass K, Lassmann H. Bone marrow-derived elements in the central nervous system: an immunohistochemical and ultrastructural survey of rat chimeras. J Neuropathol Exp Neurol 1992:51:246-256.
16. Guimareas R, Clément O, Bittoun J, Carnot F, Frija G. MR lymphography with superparamagnetic iron nanoparticles in rats: pathologic basis for contrast enhancement. AJR 1994:162:201-207.
17. Lassmann H, Suchanek G, Ozawa K. Histopathology and the blood-cerebrospinal fluid barrier in multiple sclerosis. Ann Neurol 1994;36: S42-S46.
18. Woodroofe MN. Cytokine production in the central nervous system. Neurology 1995:45(S6):S6-S10.
19. Ruuls SR, Bauer J, Sontrop K, Huitinga I, 't Hart BA, Dijkstra CD. Reactive oxygen species are involved in the pathogonesis of experimental allergic encephalomyelitis in Lewis rats. J Neuroimmunol 1995;56: 207-217.