-
1
-
-
0032431024
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Structure-based assignment of the biochemical function of a hypothetical protein: A test case of structural genomics
-
Zarembinski T.I., Hung L.W., Mueller-Dieckmann H.J., Kim K.K., Yokota H., Kim R., Kim S.-H. Structure-based assignment of the biochemical function of a hypothetical protein: a test case of structural genomics. Proc. Natl. Acad. Sci. USA. 95:1998;15189-15193.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 15189-15193
-
-
Zarembinski, T.I.1
Hung, L.W.2
Mueller-Dieckmann, H.J.3
Kim, K.K.4
Yokota, H.5
Kim, R.6
Kim, S.-H.7
-
2
-
-
0036468055
-
Structural proteomics: Developments in structure-to-function predictions
-
Norin M., Sundström M. Structural proteomics: developments in structure-to-function predictions. Trends Biotechnol. 20:2002;79-84.
-
(2002)
Trends Biotechnol.
, vol.20
, pp. 79-84
-
-
Norin, M.1
Sundström, M.2
-
4
-
-
0033785799
-
Structural proteomics of an archaeon
-
Christendat D., Yee A., Dharamsi A., Kluger Y., Savchenko A., Cort J.R., Booth V., Mackereth C.D., Saridakis V., Ekiel I. et al. Structural proteomics of an archaeon. Nat. Struct. Biol. 7:2000;903-909.
-
(2000)
Nat. Struct. Biol.
, vol.7
, pp. 903-909
-
-
Christendat, D.1
Yee, A.2
Dharamsi, A.3
Kluger, Y.4
Savchenko, A.5
Cort, J.R.6
Booth, V.7
MacKereth, C.D.8
Saridakis, V.9
Ekiel, I.10
-
5
-
-
0033757840
-
From structure to function: Approaches and limitations
-
Thornton J.M., Todd A.E., Milburn D., Borkakoti N., Orengo C.A. From structure to function: approaches and limitations. Nat. Struct. Biol. 7:2000;991-994.
-
(2000)
Nat. Struct. Biol.
, vol.7
, pp. 991-994
-
-
Thornton, J.M.1
Todd, A.E.2
Milburn, D.3
Borkakoti, N.4
Orengo, C.A.5
-
6
-
-
0036358890
-
Physiological genomics of Escherichia coli protein families
-
Liang P., Labedan B., Riley M. Physiological genomics of Escherichia coli protein families. Physiol. Genomics. 9:2002;15-26.
-
(2002)
Physiol. Genomics
, vol.9
, pp. 15-26
-
-
Liang, P.1
Labedan, B.2
Riley, M.3
-
7
-
-
0036499628
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From structure to function: YrbI from Haemophilus influenzae (HI1679) is a phosphatase
-
The realization that YrbI adopted the α/β-hydrolase fold similar to that of the haloacid dehalogenase superfamily led the authors to test a number of possible activities and reveal Mg-dependent phosphatase activity.
-
Parsons J.F., Lim K., Tempczyk A., Krajewski W., Eisenstein E., Herzberg O. From structure to function: YrbI from Haemophilus influenzae (HI1679) is a phosphatase. Proteins. 46:2002;393-404 The realization that YrbI adopted the α/β-hydrolase fold similar to that of the haloacid dehalogenase superfamily led the authors to test a number of possible activities and reveal Mg-dependent phosphatase activity.
-
(2002)
Proteins
, vol.46
, pp. 393-404
-
-
Parsons, J.F.1
Lim, K.2
Tempczyk, A.3
Krajewski, W.4
Eisenstein, E.5
Herzberg, O.6
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8
-
-
0036681398
-
Crystal structure of the YjeE protein from Haemophilus influenzae: A putative ATPase involved in cell wall synthesis
-
Teplyakov A., Obmolova G., Tordova M., Thanki N., Bonander N., Eisenstein E., Howard A.J., Gilliland G.L. Crystal structure of the YjeE protein from Haemophilus influenzae: a putative ATPase involved in cell wall synthesis. Proteins. 48:2002;220-226.
-
(2002)
Proteins
, vol.48
, pp. 220-226
-
-
Teplyakov, A.1
Obmolova, G.2
Tordova, M.3
Thanki, N.4
Bonander, N.5
Eisenstein, E.6
Howard, A.J.7
Gilliland, G.L.8
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9
-
-
0037117725
-
Identification of a novel archaebacterial thioredoxin: Determination of function through structure
-
This work reaffirms the importance of the structural proteomics approach in protein functional annotation. Structural data clearly indicated that MTH895 is a member of the glutaredoxin/thioredoxin family, and biochemical methods confirmed that it is a thioredoxin. These data and sequence comparisons identified a new class of thioredoxins, termed truncated thioredoxins.
-
Bhattacharyya S., Habibi-Nazhad B., Amegbey G., Slupsky C.M., Yee A., Arrowsmith C., Wishart D.S. Identification of a novel archaebacterial thioredoxin: determination of function through structure. Biochemistry. 41:2002;4760-4770 This work reaffirms the importance of the structural proteomics approach in protein functional annotation. Structural data clearly indicated that MTH895 is a member of the glutaredoxin/thioredoxin family, and biochemical methods confirmed that it is a thioredoxin. These data and sequence comparisons identified a new class of thioredoxins, termed truncated thioredoxins.
-
(2002)
Biochemistry
, vol.41
, pp. 4760-4770
-
-
Bhattacharyya, S.1
Habibi-Nazhad, B.2
Amegbey, G.3
Slupsky, C.M.4
Yee, A.5
Arrowsmith, C.6
Wishart, D.S.7
-
10
-
-
0037297576
-
The HI0073/HI0074 protein pair from Hemophilus influenzae is a member of a new nucleotidyltransferase family: Structure, sequence analyses, and solution studies
-
Lehman C., Lim K., Chalamasetty V.R., Krajewski W., Melamud E., Galkin A., Howard A., Kelman Z., Reddy P.T., Murzin A.G., Herzberg O. The HI0073/ HI0074 protein pair from Hemophilus influenzae is a member of a new nucleotidyltransferase family: structure, sequence analyses, and solution studies. Proteins. 50:2003;249-260.
-
(2003)
Proteins
, vol.50
, pp. 249-260
-
-
Lehman, C.1
Lim, K.2
Chalamasetty, V.R.3
Krajewski, W.4
Melamud, E.5
Galkin, A.6
Howard, A.7
Kelman, Z.8
Reddy, P.T.9
Murzin, A.G.10
Herzberg, O.11
-
11
-
-
0036179451
-
Crystal structure of MJ1247 protein from M. jannaschii at 2 Å resolution infers a molecular function of 3-hexulose 6-phosphate isomerase
-
Martinez-Cruz L.A., Dreyer M.K., Boisvert D.C., Yokota H., Martinez-Chantar M.L., Kim R., Kim S.-H. Crystal structure of MJ1247 protein from M. jannaschii at 2. Å resolution infers a molecular function of 3-hexulose 6-phosphate isomerase Structure. 10:2002;195-204.
-
(2002)
Structure
, vol.10
, pp. 195-204
-
-
Martinez-Cruz, L.A.1
Dreyer, M.K.2
Boisvert, D.C.3
Yokota, H.4
Martinez-Chantar, M.L.5
Kim, R.6
Kim, S.-H.7
-
12
-
-
0037240909
-
Structure of yeast hypothetical protein selected by a structural genomics approach
-
Eswaramoorthy S., Gerchman S., Graziano V., Kycia H., Studier F.W., Swaminathan S. Structure of yeast hypothetical protein selected by a structural genomics approach. Acta Crystallogr. D. Biol. Crystallogr. 59:2003;127-135.
-
(2003)
Acta Crystallogr. D. Biol. Crystallogr.
, vol.59
, pp. 127-135
-
-
Eswaramoorthy, S.1
Gerchman, S.2
Graziano, V.3
Kycia, H.4
Studier, F.W.5
Swaminathan, S.6
-
13
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0038309557
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Crystal complexes of a predicted S-adenosylmethionine-dependent methyltransferase reveal a typical AdoMet binding domain and a substrate recognition domain
-
Miller D.J., Ouellette N., Evdokimova E., Savchenko A., Edwards A., Anderson W.F. Crystal complexes of a predicted S-adenosylmethionine-dependent methyltransferase reveal a typical AdoMet binding domain and a substrate recognition domain. Protein Sci. 12:2003;1432-1442.
-
(2003)
Protein Sci.
, vol.12
, pp. 1432-1442
-
-
Miller, D.J.1
Ouellette, N.2
Evdokimova, E.3
Savchenko, A.4
Edwards, A.5
Anderson, W.F.6
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14
-
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0036906006
-
Structure-based experimental confirmation of biochemical function to a methyltransferase, MJ0882, from hyperthermophile Methanococcus jannaschii
-
Huang L., Hung L., Odell M., Yokota H., Kim R., Kim S.-H. Structure-based experimental confirmation of biochemical function to a methyltransferase, MJ0882, from hyperthermophile Methanococcus jannaschii. J. Struct. Funct. Genomics. 2:2002;121-127.
-
(2002)
J. Struct. Funct. Genomics
, vol.2
, pp. 121-127
-
-
Huang, L.1
Hung, L.2
Odell, M.3
Yokota, H.4
Kim, R.5
Kim, S.-H.6
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15
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0038492653
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Crystal structure of a putative methyltransferase from Mycobacterium tuberculosis: Misannotation of a genome clarified by protein structural analysis
-
This work identified an incorrect functional annotation and provided valuable information for future experiments.
-
Johnston J.M., Arcus V.L., Morton C.J., Parker M.W., Baker E.N. Crystal structure of a putative methyltransferase from Mycobacterium tuberculosis: misannotation of a genome clarified by protein structural analysis. J. Bacteriol. 185:2003;4057-4065 This work identified an incorrect functional annotation and provided valuable information for future experiments.
-
(2003)
J. Bacteriol.
, vol.185
, pp. 4057-4065
-
-
Johnston, J.M.1
Arcus, V.L.2
Morton, C.J.3
Parker, M.W.4
Baker, E.N.5
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16
-
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0036848698
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The crystal structure of MT0146/CbiT suggests that the putative precorrin-8w decarboxylase is a methyltransferase
-
Keller J.P., Smith P.M., Benach J., Christendat D., deTitta G.T., Hunt J.F. The crystal structure of MT0146/CbiT suggests that the putative precorrin-8w decarboxylase is a methyltransferase. Structure. 10:2002;1475-1487.
-
(2002)
Structure
, vol.10
, pp. 1475-1487
-
-
Keller, J.P.1
Smith, P.M.2
Benach, J.3
Christendat, D.4
Detitta, G.T.5
Hunt, J.F.6
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18
-
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0037297693
-
Deep trefoil knot implicated in RNA binding found in an archaebacterial protein
-
••] presented the experimental evidence for the presence of a deep trefoil knot fold in bacterial and archaeal proteins. These data suggest that the machinery responsible for creating the knot structure is present in bacteria, archaea and eukaryotes.
-
••] presented the experimental evidence for the presence of a deep trefoil knot fold in bacterial and archaeal proteins. These data suggest that the machinery responsible for creating the knot structure is present in bacteria, archaea and eukaryotes.
-
(2003)
Proteins
, vol.50
, pp. 177-183
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-
Zarembinski, T.I.1
Kim, Y.2
Peterson, K.3
Christendat, D.4
Dharamsi, A.5
Arrowsmith, C.H.6
Edwards, A.M.7
Joachimiak, A.8
-
19
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-
0035997122
-
An enzyme with a deep trefoil knot for the active-site architecture
-
••].
-
••].
-
(2002)
Acta Crystallogr. D Biol. Crystallogr.
, vol.58
, pp. 1129-1137
-
-
Nureki, O.1
Shirouzu, M.2
Hashimoto, K.3
Ishitani, R.4
Terada, T.5
Tamakoshi, M.6
Oshima, T.7
Chijimatsu, M.8
Takio, K.9
Vassylyev, D.G.10
-
20
-
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0037443092
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Structure and function of the PWI motif: A novel nucleic acid-binding domain that facilitates pre-mRNA processing
-
This study presents a combined structural and functional characterization of the PWI motif, a highly conserved domain of unknown function present in many pre-mRNA processing proteins. A new mode of nucleic acid binding has been revealed with a similar binding affinity for single- and double-stranded nucleic acid.
-
Szymczyna B.R., Bowman J., McCracken S., Pineda-Lucena A., Lu Y., Cox B., Lambermon M., Graveley B.R., Arrowsmith C.H., Blencowe B.J. Structure and function of the PWI motif: a novel nucleic acid-binding domain that facilitates pre-mRNA processing. Genes Dev. 17:2003;461-475 This study presents a combined structural and functional characterization of the PWI motif, a highly conserved domain of unknown function present in many pre-mRNA processing proteins. A new mode of nucleic acid binding has been revealed with a similar binding affinity for single- and double-stranded nucleic acid.
-
(2003)
Genes Dev.
, vol.17
, pp. 461-475
-
-
Szymczyna, B.R.1
Bowman, J.2
McCracken, S.3
Pineda-Lucena, A.4
Lu, Y.5
Cox, B.6
Lambermon, M.7
Graveley, B.R.8
Arrowsmith, C.H.9
Blencowe, B.J.10
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21
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0042490664
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The RNA-binding SAM domain of Smaug defines a new family of post-transcriptional regulators
-
••] have identified the SAM domain of Drosophila Smaug protein as an RNA-binding domain and defined a new family of SAM RNA-binding proteins. Thus, the SAM domain is able to interact with both proteins and nucleic acids.
-
••] have identified the SAM domain of Drosophila Smaug protein as an RNA-binding domain and defined a new family of SAM RNA-binding proteins. Thus, the SAM domain is able to interact with both proteins and nucleic acids.
-
(2003)
Nat. Struct. Biol.
, vol.10
, pp. 614-621
-
-
Aviv, T.1
Lin, Z.2
Lau, S.3
Rendl, L.M.4
Sicheri, F.5
Smibert, C.A.6
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23
-
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1842832249
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Crystal structure of E. coli YhbY: A representative of a novel class of RNA binding proteins
-
Ostheimer G.J., Barkan A., Matthews B.W. Crystal structure of E. coli YhbY: a representative of a novel class of RNA binding proteins. Structure. 10:2002;1593-1601.
-
(2002)
Structure
, vol.10
, pp. 1593-1601
-
-
Ostheimer, G.J.1
Barkan, A.2
Matthews, B.W.3
-
24
-
-
0037110588
-
Structure of HI1333 (YhbY), a putative RNA-binding protein from Haemophilus influenzae
-
Willis M.A., Krajewski W., Chalamasetty V.R., Reddy P., Howard A., Herzberg O. Structure of HI1333 (YhbY), a putative RNA-binding protein from Haemophilus influenzae. Proteins. 49:2002;423-426.
-
(2002)
Proteins
, vol.49
, pp. 423-426
-
-
Willis, M.A.1
Krajewski, W.2
Chalamasetty, V.R.3
Reddy, P.4
Howard, A.5
Herzberg, O.6
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25
-
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0038600722
-
The solution structure of YbcJ from Escherichia coli reveals a recently discovered αl motif involved in RNA binding
-
Volpon L., Lievre C., Osborne M.J., Gandhi S., Iannuzzi P., Larocque R., Cygler M., Gehring K., Ekiel I. The solution structure of YbcJ from Escherichia coli reveals a recently discovered αL motif involved in RNA binding. J. Bacteriol. 185:2003;4204-4210.
-
(2003)
J. Bacteriol.
, vol.185
, pp. 4204-4210
-
-
Volpon, L.1
Lievre, C.2
Osborne, M.J.3
Gandhi, S.4
Iannuzzi, P.5
Larocque, R.6
Cygler, M.7
Gehring, K.8
Ekiel, I.9
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26
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0034491066
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The structure of the yrdC gene product from Escherichia coli reveals a new fold and suggests a role in RNA binding
-
Teplova M., Tereshko V., Sanishvili R., Joachimiak A., Bushueva T., Anderson W.F., Egli M. The structure of the yrdC gene product from Escherichia coli reveals a new fold and suggests a role in RNA binding. Protein Sci. 9:2000;2557-2566.
-
(2000)
Protein Sci.
, vol.9
, pp. 2557-2566
-
-
Teplova, M.1
Tereshko, V.2
Sanishvili, R.3
Joachimiak, A.4
Bushueva, T.5
Anderson, W.F.6
Egli, M.7
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27
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0036780778
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Crystal structure of the YciO protein from Escherichia coli
-
Jia J., Lunin V.V., Sauve V., Huang L.-W., Matte A., Cygler M. Crystal structure of the YciO protein from Escherichia coli. Proteins. 49:2002;139-141.
-
(2002)
Proteins
, vol.49
, pp. 139-141
-
-
Jia, J.1
Lunin, V.V.2
Sauve, V.3
Huang, L.-W.4
Matte, A.5
Cygler, M.6
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28
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0037295566
-
Crystal structure of YbaB from Haemophilus influenzae (HI0442), a protein of unknown function coexpressed with the recombinational DNA repair protein RecR
-
Lim K., Tempczyk A., Parsons J.F., Bonander N., Toedt J., Kelman Z., Howard A., Eisenstein E., Herzberg O. Crystal structure of YbaB from Haemophilus influenzae (HI0442), a protein of unknown function coexpressed with the recombinational DNA repair protein RecR. Proteins. 50:2003;375-379.
-
(2003)
Proteins
, vol.50
, pp. 375-379
-
-
Lim, K.1
Tempczyk, A.2
Parsons, J.F.3
Bonander, N.4
Toedt, J.5
Kelman, Z.6
Howard, A.7
Eisenstein, E.8
Herzberg, O.9
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29
-
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0037816443
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Crystal structure of the YchF protein reveals binding sites for GTP and nucleic acid
-
Teplyakov A., Obmolova G., Chu S.Y., Toedt J., Eisenstein E., Howard A.J., Gilliland G.L. Crystal structure of the YchF protein reveals binding sites for GTP and nucleic acid. J. Bacteriol. 185:2003;4031-4037.
-
(2003)
J. Bacteriol.
, vol.185
, pp. 4031-4037
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-
Teplyakov, A.1
Obmolova, G.2
Chu, S.Y.3
Toedt, J.4
Eisenstein, E.5
Howard, A.J.6
Gilliland, G.L.7
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30
-
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0037233841
-
X-ray structure of an M. jannaschii DNA-binding protein: Implications for antibiotic resistance in S. aureus
-
Ray S.S., Bonanno J.B., Chen H., de Lencastre H., Wu S., Tomasz A., Burley S.K. X-ray structure of an M. jannaschii DNA-binding protein: implications for antibiotic resistance in S. aureus. Proteins. 50:2003;170-173.
-
(2003)
Proteins
, vol.50
, pp. 170-173
-
-
Ray, S.S.1
Bonanno, J.B.2
Chen, H.3
De Lencastre, H.4
Wu, S.5
Tomasz, A.6
Burley, S.K.7
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31
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0043173988
-
Crystal structure of MTH1187 and its yeast ortholog YBL001c
-
Tao X., Khayat R., Christendat D., Savchenko A., Xu X., Goldsmith-Fischman S., Honig B., Edwards A., Arrowsmith C.H., Tong L. Crystal structure of MTH1187 and its yeast ortholog YBL001c. Proteins. 52:2003;478-480.
-
(2003)
Proteins
, vol.52
, pp. 478-480
-
-
Tao, X.1
Khayat, R.2
Christendat, D.3
Savchenko, A.4
Xu, X.5
Goldsmith-Fischman, S.6
Honig, B.7
Edwards, A.8
Arrowsmith, C.H.9
Tong, L.10
-
32
-
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0036836521
-
Crystal structure of MTH169, a crucial component of phosphoribosylformylglycinamidine synthetase
-
Batra R., Christendat D., Edwards A., Arrowsmith C., Tong L. Crystal structure of MTH169, a crucial component of phosphoribosylformylglycinamidine synthetase. Proteins. 49:2002;285-288.
-
(2002)
Proteins
, vol.49
, pp. 285-288
-
-
Batra, R.1
Christendat, D.2
Edwards, A.3
Arrowsmith, C.4
Tong, L.5
-
33
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-
0035836765
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A comprehensive two-hybrid analysis to explore the yeast protein interactome
-
Ito T., Chiba T., Ozawa R., Yoshida M., Hattori M., Sakaki Y. A comprehensive two-hybrid analysis to explore the yeast protein interactome. Proc. Natl. Acad. Sci. USA. 98:2001;4569-4574.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 4569-4574
-
-
Ito, T.1
Chiba, T.2
Ozawa, R.3
Yoshida, M.4
Hattori, M.5
Sakaki, Y.6
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34
-
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0037343179
-
Crystal structure of a hypothetical protein, TM841 of Thermotoga maritima, reveals its function as a fatty acid-binding protein
-
Schulze-Gahmen U., Pelaschier J., Yokota H., Kim R., Kim S.-H. Crystal structure of a hypothetical protein, TM841 of Thermotoga maritima, reveals its function as a fatty acid-binding protein. Proteins. 50:2003;526-530.
-
(2003)
Proteins
, vol.50
, pp. 526-530
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-
Schulze-Gahmen, U.1
Pelaschier, J.2
Yokota, H.3
Kim, R.4
Kim, S.-H.5
-
35
-
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0037424378
-
Aspartate dehydrogenase, a novel enzyme identified from structural and functional studies of TM1643
-
This work represents the successful application of structural studies in combination with enzymatic screening for catalytic activity, which quickly identified a biochemical function for an unknown protein. This protein and its homologues established a new class of amino acid dehydrogenases, L-aspartate dehydrogenases.
-
Yang Z., Savchenko A., Yakunin A., Zhang R., Edwards A., Arowsmith C., Tong L. Aspartate dehydrogenase, a novel enzyme identified from structural and functional studies of TM1643. J. Biol. Chem. 278:2003;8804-8808 This work represents the successful application of structural studies in combination with enzymatic screening for catalytic activity, which quickly identified a biochemical function for an unknown protein. This protein and its homologues established a new class of amino acid dehydrogenases, L-aspartate dehydrogenases.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 8804-8808
-
-
Yang, Z.1
Savchenko, A.2
Yakunin, A.3
Zhang, R.4
Edwards, A.5
Arowsmith, C.6
Tong, L.7
-
36
-
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0027996242
-
The 47-kDa major lipoprotein immunogen of Treponema pallidum is a penicillin-binding protein with carboxypeptidase activity
-
Weigel L.M., Radolf J.D., Norgard M.V. The 47-kDa major lipoprotein immunogen of Treponema pallidum is a penicillin-binding protein with carboxypeptidase activity. Proc. Natl. Acad. Sci. USA. 91:1994;11611-11615.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 11611-11615
-
-
Weigel, L.M.1
Radolf, J.D.2
Norgard, M.V.3
-
37
-
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0036829594
-
Crystal structure of the 47-kDa lipoprotein of Treponema pallidum reveals a novel penicillin-binding protein
-
Deka R.K., Machius M., Norgard M.V., Tomchick D.R. Crystal structure of the 47-kDa lipoprotein of Treponema pallidum reveals a novel penicillin-binding protein. J. Biol. Chem. 277:2002;41857-41864.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 41857-41864
-
-
Deka, R.K.1
MacHius, M.2
Norgard, M.V.3
Tomchick, D.R.4
-
38
-
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0037402602
-
Crystal structure of the Escherichia coli YcdX protein reveals a trinuclear zinc active site
-
Teplyakov A., Obmolova G., Khil P.P., Howard A.J., Camerini-Otero R.D., Gilliland G.L. Crystal structure of the Escherichia coli YcdX protein reveals a trinuclear zinc active site. Proteins. 51:2003;315-318.
-
(2003)
Proteins
, vol.51
, pp. 315-318
-
-
Teplyakov, A.1
Obmolova, G.2
Khil, P.P.3
Howard, A.J.4
Camerini-Otero, R.D.5
Gilliland, G.L.6
-
39
-
-
0036224939
-
Over 1000 genes are involved in the DNA damage response of Escherichia coli
-
Khil P.P., Camerini-Otero R.D. Over 1000 genes are involved in the DNA damage response of Escherichia coli. Mol. Microbiol. 44:2002;89-105.
-
(2002)
Mol. Microbiol.
, vol.44
, pp. 89-105
-
-
Khil, P.P.1
Camerini-Otero, R.D.2
-
40
-
-
0036836543
-
NMR structure of the Escherichia coli protein YacG: A novel sequence motif in the zinc-finger family of proteins
-
Ramelot T.A., Cort J.R., Yee A.A., Semesi A., Edwards A.M., Arrowsmith C.H., Kennedy M.A. NMR structure of the Escherichia coli protein YacG: a novel sequence motif in the zinc-finger family of proteins. Proteins. 49:2002;289-293.
-
(2002)
Proteins
, vol.49
, pp. 289-293
-
-
Ramelot, T.A.1
Cort, J.R.2
Yee, A.A.3
Semesi, A.4
Edwards, A.M.5
Arrowsmith, C.H.6
Kennedy, M.A.7
-
41
-
-
0242290210
-
YodA from Escherichia coli is a metal-binding, lipocalin-like protein
-
David G., Blondeau K., Schiltz M., Penel S., Lewit-Bentley A. YodA from Escherichia coli is a metal-binding, lipocalin-like protein. J. Biol. Chem. 278:2003;43728-43735.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 43728-43735
-
-
David, G.1
Blondeau, K.2
Schiltz, M.3
Penel, S.4
Lewit-Bentley, A.5
-
42
-
-
0028965483
-
Molecular genetics of a chromosomal locus involved in copper tolerance in Escherichia coli K-12
-
Fong S.T., Camakaris J., Lee B.T. Molecular genetics of a chromosomal locus involved in copper tolerance in Escherichia coli K-12. Mol. Microbiol. 15:1995;1127-1137.
-
(1995)
Mol. Microbiol.
, vol.15
, pp. 1127-1137
-
-
Fong, S.T.1
Camakaris, J.2
Lee, B.T.3
-
43
-
-
0242412534
-
The evolutionary conserved trimeric structure of CutA1 proteins suggests a role in signal transduction
-
Arnesano F., Banci L., Benvenuti M., Bertini I., Calderone V., Mangani S., Viezzoli M.S. The evolutionary conserved trimeric structure of CutA1 proteins suggests a role in signal transduction. J. Biol. Chem. 278:2003;45999-46006.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 45999-46006
-
-
Arnesano, F.1
Banci, L.2
Benvenuti, M.3
Bertini, I.4
Calderone, V.5
Mangani, S.6
Viezzoli, M.S.7
-
44
-
-
0038168191
-
Integrating structure, bioinformatics, and enzymology to discover function. BioH, a new carboxylesterase from Escherichia coli
-
A clear illustration of how the combined use of structural studies, structural bioinformatics, and enzymatic screening for catalytic activity can greatly increase the rate at which function is determined from structure.
-
Sanishvili R., Yakunin A.F., Laskowski R., Skarina T., Evdokimova E., Doherty-Kirby A., Lajoie G.A., Thornton J.M., Arrowsmith C.H., Savchenko A. et al. Integrating structure, bioinformatics, and enzymology to discover function. BioH, a new carboxylesterase from Escherichia coli. J. Biol. Chem. 278:2003;26039-26045 A clear illustration of how the combined use of structural studies, structural bioinformatics, and enzymatic screening for catalytic activity can greatly increase the rate at which function is determined from structure.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 26039-26045
-
-
Sanishvili, R.1
Yakunin, A.F.2
Laskowski, R.3
Skarina, T.4
Evdokimova, E.5
Doherty-Kirby, A.6
Lajoie, G.A.7
Thornton, J.M.8
Arrowsmith, C.H.9
Savchenko, A.10
-
45
-
-
0030069708
-
To be free or not: The fate of pimelate in Bacillus sphaericus and in Escherichia coli
-
Lemoine Y., Wach A., Jeltsch J.M. To be free or not: the fate of pimelate in Bacillus sphaericus and in Escherichia coli. Mol. Microbiol. 19:1996;645-647.
-
(1996)
Mol. Microbiol.
, vol.19
, pp. 645-647
-
-
Lemoine, Y.1
Wach, A.2
Jeltsch, J.M.3
-
46
-
-
0037435625
-
Solution structure and functional ligand screening of HI0719, a highly conserved protein from bacteria to humans in the YjgF/YER057c/UK114 family
-
Combination of structural studies and functional ligand screening using NMR narrowed down the potential ligands for unknown protein. Further technical developments of this functional ligand screening will make this technology amenable for high-throughput application.
-
Parsons L., Bonander N., Eisenstein E., Gilson M., Kairys V., Orban J. Solution structure and functional ligand screening of HI0719, a highly conserved protein from bacteria to humans in the YjgF/YER057c/UK114 family. Biochemistry. 42:2003;80-89 Combination of structural studies and functional ligand screening using NMR narrowed down the potential ligands for unknown protein. Further technical developments of this functional ligand screening will make this technology amenable for high-throughput application.
-
(2003)
Biochemistry
, vol.42
, pp. 80-89
-
-
Parsons, L.1
Bonander, N.2
Eisenstein, E.3
Gilson, M.4
Kairys, V.5
Orban, J.6
-
47
-
-
0037375572
-
Structure of the YibK methyltransferase from Haemophilus influenzae (HI0766): A cofactor bound at a site formed by a knot
-
Lim K., Zhang H., Tempczyk A., Krajewski W., Bonander N., Toedt J., Howard A., Eisenstein E., Herzberg O. Structure of the YibK methyltransferase from Haemophilus influenzae (HI0766): a cofactor bound at a site formed by a knot. Proteins. 51:2003;56-67.
-
(2003)
Proteins
, vol.51
, pp. 56-67
-
-
Lim, K.1
Zhang, H.2
Tempczyk, A.3
Krajewski, W.4
Bonander, N.5
Toedt, J.6
Howard, A.7
Eisenstein, E.8
Herzberg, O.9
-
48
-
-
0141704142
-
Functional assignment based on structural analysis: Crystal structure of the YggJ protein (HI0303) of Haemophilus influenzae reveals an RNA methyltransferase with a deep trefoil knot
-
Forouhar F., Shen J., Xiao R., Acton T.B., Montelione G.T., Tong L. Functional assignment based on structural analysis: crystal structure of the YggJ protein (HI0303) of Haemophilus influenzae reveals an RNA methyltransferase with a deep trefoil knot. Proteins. 53:2003;329-332.
-
(2003)
Proteins
, vol.53
, pp. 329-332
-
-
Forouhar, F.1
Shen, J.2
Xiao, R.3
Acton, T.B.4
Montelione, G.T.5
Tong, L.6
-
49
-
-
9144241174
-
Structure and function-based characterization of a new phosphoglycolate phosphatase from Thermoplasma acidophilum
-
in press
-
Kim Y, Yakunin AF, Kuznetsova E, Xu X, Pennycooke M, Gu J, Cheung F, Proudfoot M, Arrowsmith CH, Joachimiak A et al.: Structure and function-based characterization of a new phosphoglycolate phosphatase from Thermoplasma acidophilum. J Biol Chem 2003, in press.
-
(2003)
J Biol Chem
-
-
Kim, Y.1
Yakunin, A.F.2
Kuznetsova, E.3
Xu, X.4
Pennycooke, M.5
Gu, J.6
Cheung, F.7
Proudfoot, M.8
Arrowsmith, C.H.9
Joachimiak, A.10
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