Structure and function of the PWI motif: A novel nucleic acid-binding domain that facilitates pre-MRNA processing

Genes and Development

Volumn 17, Issue 4, 2003, Pages 461-475

  Szymczyna, Blair R ^a   Bowman, John ^a,b   McCracken, Susan ^b   Pineda Lucena, Antonio ^a   Lu, Ying ^a   Cox, Brian ^c   Lambermon, Mark ^b   Graveley, Brenton R ^d   Arrowsmith, Cheryl H ^a   Blencowe, Benjamin J ^a,b  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c Affinium Pharmaceuticals   (Canada)

^d UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

Author keywords

3 end cleavage; RNA binding domain; Spliceosome

Indexed keywords

DOUBLE STRANDED DNA; MESSENGER RNA; NUCLEIC ACID BINDING PROTEIN; PROTEIN PWI; SINGLE STRANDED DNA; UNCLASSIFIED DRUG;

ALPHA HELIX; ARTICLE; CONTROLLED STUDY; DNA BINDING; DNA CLEAVAGE; EMBRYO; GENE DELETION; HUMAN; HUMAN CELL; MUTAGENESIS; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN STRUCTURE; RNA BINDING; RNA PROCESSING; RNA SPLICING; SPLICEOSOME; STRUCTURE ANALYSIS;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANTIGENS, NUCLEAR; BINDING SITES; CONSERVED SEQUENCE; HELA CELLS; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NUCLEAR MATRIX-ASSOCIATED PROTEINS; NUCLEIC ACIDS; PROTEIN CONFORMATION; RNA PRECURSORS; RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA SPLICING; RNA-BINDING PROTEINS; SEQUENCE DELETION;

EID: 0037443092     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.1060403     Document Type: Article

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