The crystal structure of MT0146/CbiT suggests that the putative precorrin-8w decarboxylase is a methyltransferase

Structure

Volumn 10, Issue 11, 2002, Pages 1475-1487

  Keller, Jacob P ^a   Smith, Paul M ^a   Benach, Jordi ^a   Christendat, Dinesh ^b   De Titta, George T ^c   Hunt, John F ^a  

^a Columbia University ^*  (United States)

^b UNIVERSITY HEALTH NETWORK   (Canada)

^c HAUPTMAN WOODWARD MEDICAL RESEARCH INSTITUTE   (United States)

Author keywords

Decarboxylase; Methyltransferase; S adenosyl methionine; Structural genomics; Structure based function assignment; Vitamin B12

Indexed keywords

BACTERIAL PROTEIN; CARBOXYLYASE; METHYLTRANSFERASE; PROTEIN CBIT; PROTEIN MTO146; S ADENOSYLMETHIONINE; UNCLASSIFIED DRUG; PRECORRIN 8W METHYLTRANSFERASE; PRECORRIN-8W METHYLTRANSFERASE;

ARTICLE; BINDING SITE; CRYSTAL STRUCTURE; CRYSTALLIZATION; ENZYME ACTIVITY; HYDROGEN BOND; METHANOBACTERIUM THERMOAUTOTROPHICUM; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; AMINO ACID SEQUENCE; CHEMICAL MODEL; CHEMICAL STRUCTURE; CHEMISTRY; DIMERIZATION; METABOLISM; METHANOBACTERIUM; MOLECULAR CLONING; MOLECULAR GENETICS; PROMOTER REGION; PROTEIN FOLDING; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; X RAY CRYSTALLOGRAPHY;

BACTERIA (MICROORGANISMS); METHANOBACTERIUM; METHANOTHERMOBACTER THERMAUTOTROPHICUS;

AMINO ACID SEQUENCE; BINDING SITES; CLONING, MOLECULAR; CRYSTALLOGRAPHY, X-RAY; DIMERIZATION; METHANOBACTERIUM; METHYLTRANSFERASES; MODELS, CHEMICAL; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROMOTER REGIONS (GENETICS); PROTEIN BINDING; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; S-ADENOSYLMETHIONINE; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 0036848698     PISSN: 09692126     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-2126(02)00876-6     Document Type: Article

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