The use of animal models in the study of complex disease: All else is never equal or why do so many human studies fail to replicate animal findings?

BioEssays

Volumn 26, Issue 2, 2004, Pages 170-179

  Williams, Scott M ^a,b   Haines, Jonathan L ^b   Moore, Jason H ^b  

^a VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL MODEL; DISEASE MODEL; GENE INTERACTION; GENE REPLICATION; GENETIC ANALYSIS; GENETIC MODEL; GENETIC RISK; GENETIC VARIABILITY; GENETICS; GENOTYPE; HEREDITY; HUMAN EXPERIMENT; HYPERTENSION; METHODOLOGY; PHENOTYPE; REVIEW; RISK FACTOR;

ANIMALS; DISEASE; DISEASE MODELS, ANIMAL; EPISTASIS, GENETIC; GENETIC PREDISPOSITION TO DISEASE; HUMANS; HYPERTENSION; LINKAGE (GENETICS); PHENOTYPE;

ANIMALIA;

EID: 1042268174     PISSN: 02659247     EISSN: None     Source Type: Journal    
DOI: 10.1002/bies.10401     Document Type: Review

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