Model structures of the N-methyl-D-aspartate receptor subunit NR1 explain the molecular recognition of agonist and antagonist ligands

Journal of Structural Biology

Volumn 145, Issue 3, 2004, Pages 205-215

  Moretti, Loris ^a   Pentikäinen, Olli T ^a   Settimo, Luca ^a   Johnson, Mark S ^a  

^a ÅBO AKADEMI UNIVERSITY   (Finland)

Author keywords

Agonist binding; Antagonist binding; Ionotropic glutamate receptors; Model structures; NMDA receptor; NR1 subunit

Indexed keywords

3 (2 CARBOXY 2 PHENYLETHENYL) 4,6 DICHLORO 1H INDOLE 2 CARBOXYLIC ACID; 5,7 DICHLORO 4 OXO 1,4 DIHYDROQUINOLINE 2 CARBOXYLIC ACID; ALANINE DERIVATIVE; BACTERIAL PROTEIN; BINDING PROTEIN; CYCLOSERINE; GLUTAMATE RECEPTOR; GLUTAMINE BINDING PROTEIN; GLYCINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; N METHYL DEXTRO ASPARTIC ACID RECEPTOR STIMULATING AGENT; RECEPTOR SUBUNIT; SERINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG BINDING SITE; DRUG RECEPTOR BINDING; HUMAN; HYDROGEN BOND; HYDROPHOBICITY; LIGAND BINDING; MOLECULAR MODEL; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; RAT; STRUCTURE ANALYSIS; WILD TYPE;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 1042267373     PISSN: 10478477     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jsb.2003.10.016     Document Type: Article

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