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Volumn 25, Issue 12, 2004, Pages 2293-2301

Organ-selective chemoresistance in metastasis from human breast cancer cells: Inhibition of apoptosis, genetic variability and microenvironment at the metastatic focus

Author keywords

[No Author keywords available]

Indexed keywords

DOCETAXEL; DOXORUBICIN; GENE PRODUCT; GENOMIC DNA; LUCIFERASE; NEOMYCIN; PACLITAXEL; PROTEIN BCL XL; TUMOR MARKER; VINCRISTINE;

EID: 10344250398     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/bgh272     Document Type: Article
Times cited : (27)

References (53)
  • 1
    • 0037234360 scopus 로고    scopus 로고
    • Predicting the future of breast cancer
    • Borg,A., Ferno,M. and Peterson,C. (2003) Predicting the future of breast cancer. Nature Med., 9, 16-18.
    • (2003) Nature Med. , vol.9 , pp. 16-18
    • Borg, A.1    Ferno, M.2    Peterson, C.3
  • 2
    • 0032930312 scopus 로고    scopus 로고
    • Dr. Josef Steiner Cancer Research Prize Lecture: The role of physiological cell death in neoplastic transformation and in anti-cancer therapy
    • Strasser,A. (1999) Dr. Josef Steiner Cancer Research Prize Lecture: the role of physiological cell death in neoplastic transformation and in anti-cancer therapy. Int. J. Cancer, 81 505-511.
    • (1999) Int. J. Cancer , vol.81 , pp. 505-511
    • Strasser, A.1
  • 3
    • 0031577702 scopus 로고    scopus 로고
    • Suppression of apoptosis by bcl-2 does not prevent p53-mediated control of experimental metastasis and anchorage dependence
    • Nikiforov,M.A., Kwek,S.S., Mehta,R., Artwohl,J.E., Lowe,S.W., Gupta,T.D., Deichman,G.I. and Gudkov,A.V. (1997) Suppression of apoptosis by bcl-2 does not prevent p53-mediated control of experimental metastasis and anchorage dependence. Oncogene, 15, 3007-3012.
    • (1997) Oncogene , vol.15 , pp. 3007-3012
    • Nikiforov, M.A.1    Kwek, S.S.2    Mehta, R.3    Artwohl, J.E.4    Lowe, S.W.5    Gupta, T.D.6    Deichman, G.I.7    Gudkov, A.V.8
  • 7
    • 0033491603 scopus 로고    scopus 로고
    • Recent progress on the regulation of apoptosis by Bcl-2 family members
    • Minn,A.J., Swain,R.E., Ma,A. and Thompson,C.B. (1998) Recent progress on the regulation of apoptosis by Bcl-2 family members. Adv. Immunol., 70, 245-279.
    • (1998) Adv. Immunol. , vol.70 , pp. 245-279
    • Minn, A.J.1    Swain, R.E.2    Ma, A.3    Thompson, C.B.4
  • 8
    • 0033635733 scopus 로고    scopus 로고
    • BH3-Only proteins - Essential initiators of apoptotic cell death
    • Huang,D.C. and Strasser,A. (2000) BH3-Only proteins - essential initiators of apoptotic cell death. Cell, 103, 839-842.
    • (2000) Cell , vol.103 , pp. 839-842
    • Huang, D.C.1    Strasser, A.2
  • 9
    • 0030916669 scopus 로고    scopus 로고
    • The proto-oncogene Bcl-2 and its role in regulating apoptosis
    • Kroemer,G. (1997) The proto-oncogene Bcl-2 and its role in regulating apoptosis. Nature Med., 3, 614-620.
    • (1997) Nature Med. , vol.3 , pp. 614-620
    • Kroemer, G.1
  • 10
    • 0032863163 scopus 로고    scopus 로고
    • All along the watch-tower: On the regulation of apoptosis regulators
    • Fadeel,B., Zhivotovsky,B. and Orrenius,S. (1999) All along the watch-tower: on the regulation of apoptosis regulators. FASEB J. 13, 1647-1657.
    • (1999) FASEB J. , vol.13 , pp. 1647-1657
    • Fadeel, B.1    Zhivotovsky, B.2    Orrenius, S.3
  • 11
    • 0033179760 scopus 로고    scopus 로고
    • BCL-2 family members and the mitochondria in apoptosis
    • Gross,A., McDonnell,J.M. and Korsmeyer,S.J. (1999) BCL-2 family members and the mitochondria in apoptosis. Genes Dev., 13 1899-1911.
    • (1999) Genes Dev. , vol.13 , pp. 1899-1911
    • Gross, A.1    McDonnell, J.M.2    Korsmeyer, S.J.3
  • 12
    • 0032129272 scopus 로고    scopus 로고
    • Bcl-xL is phosphorylated in malignant cells following microtubule disruption
    • Poruchynsky,M.S., Wang,E.E., Rudin,C.M., Blagosklonny,M.V. and Fojo,T. (1998) Bcl-xL is phosphorylated in malignant cells following microtubule disruption. Cancer Res., 58, 3331-3338.
    • (1998) Cancer Res. , vol.58 , pp. 3331-3338
    • Poruchynsky, M.S.1    Wang, E.E.2    Rudin, C.M.3    Blagosklonny, M.V.4    Fojo, T.5
  • 13
    • 0031032294 scopus 로고    scopus 로고
    • Bcl-2 and Bcl-XL antagonize the mitochondrial dysfunction preceding nuclear apoptosis induced by chemotherapeutic agents
    • Decaudin,D., Geley,S., Hirsch,T., Castedo,M., Marchetti,P., Macho,A., Kofler,R. and Kroemer,G. (1997) Bcl-2 and Bcl-XL antagonize the mitochondrial dysfunction preceding nuclear apoptosis induced by chemotherapeutic agents. Cancer Res., 57, 62-67.
    • (1997) Cancer Res. , vol.57 , pp. 62-67
    • Decaudin, D.1    Geley, S.2    Hirsch, T.3    Castedo, M.4    Marchetti, P.5    Macho, A.6    Kofler, R.7    Kroemer, G.8
  • 14
    • 0031035693 scopus 로고    scopus 로고
    • Bcl2 is the guardian of microtubule integrity
    • Haldar,S., Basu,A. and Croce,C.M. (1997) Bcl2 is the guardian of microtubule integrity. Cancer Res., 57, 229-233.
    • (1997) Cancer Res. , vol.57 , pp. 229-233
    • Haldar, S.1    Basu, A.2    Croce, C.M.3
  • 15
    • 0032145442 scopus 로고    scopus 로고
    • 'Loop' domain is necessary for taxol-induced mobility shift and phosphorylation of Bcl-2 as well as for inhibiting taxol-induced cytosolic accumulation of cytochrome c and apoptosis
    • Fang,G., Chang,B.S., Kim,C.N., Perkins,C., Thompson,C.B. and Bhalla,K.N. (1998) 'Loop' domain is necessary for taxol-induced mobility shift and phosphorylation of Bcl-2 as well as for inhibiting taxol-induced cytosolic accumulation of cytochrome c and apoptosis. Cancer Res., 58, 3202-3208.
    • (1998) Cancer Res. , vol.58 , pp. 3202-3208
    • Fang, G.1    Chang, B.S.2    Kim, C.N.3    Perkins, C.4    Thompson, C.B.5    Bhalla, K.N.6
  • 16
    • 0036783399 scopus 로고    scopus 로고
    • Inhibition of apoptosis in human breast cancer cells: Role in tumor progression to the metastatic state
    • Fernandez,Y., Gu,B., Martinez,A., Torregrosa,A. and Sierra,A. (2002) Inhibition of apoptosis in human breast cancer cells: role in tumor progression to the metastatic state. Int. J. Cancer, 101 317-326.
    • (2002) Int. J. Cancer , vol.101 , pp. 317-326
    • Fernandez, Y.1    Gu, B.2    Martinez, A.3    Torregrosa, A.4    Sierra, A.5
  • 17
    • 0037206950 scopus 로고    scopus 로고
    • Resistance to chemotherapy via Stat3-dependent overexpression of Bcl-2 in metastatic breast cancer cells
    • Real,P.J., Sierra,A., De Juan,A., Segovia,J.C., Lopez-Vega,J.M. and Fernandez-Luna,J.L. (2002) Resistance to chemotherapy via Stat3-dependent overexpression of Bcl-2 in metastatic breast cancer cells. Oncogene, 21, 7611-7618.
    • (2002) Oncogene , vol.21 , pp. 7611-7618
    • Real, P.J.1    Sierra, A.2    De Juan, A.3    Segovia, J.C.4    Lopez-Vega, J.M.5    Fernandez-Luna, J.L.6
  • 18
    • 0035016397 scopus 로고    scopus 로고
    • Metastatic behavior of human breast carcinomas overexpressing the Bcl-x (L) gene: A role in dormancy and organospecificity
    • Rubio,N., Espana,L., Fernandez,Y., Blanco,J. and Sierra,A. (2001) Metastatic behavior of human breast carcinomas overexpressing the Bcl-x (L) gene: a role in dormancy and organospecificity. Lab. Invest. 81, 725-734.
    • (2001) Lab. Invest. , vol.81 , pp. 725-734
    • Rubio, N.1    Espana, L.2    Fernandez, Y.3    Blanco, J.4    Sierra, A.5
  • 19
    • 0026351389 scopus 로고
    • Relative malignant potential of human breast carcinoma cell lines established from pleural effusions and a brain metastasis
    • Zhang,R.D., Fidler,I.J. and Price,J.E. (1991) Relative malignant potential of human breast carcinoma cell lines established from pleural effusions and a brain metastasis. Invasion Metast., 11 204-215.
    • (1991) Invasion Metast. , vol.11 , pp. 204-215
    • Zhang, R.D.1    Fidler, I.J.2    Price, J.E.3
  • 20
    • 85177145318 scopus 로고    scopus 로고
    • Bcl-x and Bcl-2 inhibit TNT and Fas-induced apoptosis and activation of phospholipase A2 in breast carcinoma cells
    • al',J.A.S.e
    • Jäättelä,M., Benedict,M., Tewari,M. and al',J.A.S.e. Bcl-x and Bcl-2 inhibit TNT and Fas-induced apoptosis and activation of phospholipase A2 in breast carcinoma cells. Oncogene.
    • Oncogene
    • Jäättelä, M.1    Benedict, M.2    Tewari, M.3
  • 21
    • 0032763060 scopus 로고    scopus 로고
    • Overexpression of Bcl-x (L) promotes chemotherapy resistance of mammary tumors in a syngeneic mouse model
    • Liu,R., Page,C., Beidler,D.R., Wicha,M.S. and Nunez,G. (1999) Overexpression of Bcl-x (L) promotes chemotherapy resistance of mammary tumors in a syngeneic mouse model. Am. J. Pathol., 155, 1861-1867.
    • (1999) Am. J. Pathol. , vol.155 , pp. 1861-1867
    • Liu, R.1    Page, C.2    Beidler, D.R.3    Wicha, M.S.4    Nunez, G.5
  • 22
    • 12944272151 scopus 로고    scopus 로고
    • Fibroblast growth factors: An epigenetic mechanism of broad spectrum resistance to anticancer drugs
    • Song,S., Wientjes,M.G., Gan,Y. and Au,J.L. (2000) Fibroblast growth factors: an epigenetic mechanism of broad spectrum resistance to anticancer drugs. Proc. Natl Acad. Sci. USA, 97, 8658-8663.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 8658-8663
    • Song, S.1    Wientjes, M.G.2    Gan, Y.3    Au, J.L.4
  • 24
    • 0034606645 scopus 로고    scopus 로고
    • Genetic and epigenetic factors in anticancer drug resistance
    • Shoemaker,R.H. (2000) Genetic and epigenetic factors in anticancer drug resistance. J. Natl Cancer Inst., 92, 4-5.
    • (2000) J. Natl Cancer Inst. , vol.92 , pp. 4-5
    • Shoemaker, R.H.1
  • 25
    • 0034606657 scopus 로고    scopus 로고
    • Epigenetic determinants of resistance to etoposide regulation of Bcl-X (L) and Bax by tumor microenvironmental factors
    • Taylor,S.T., Hickman,J.A. and Dive,C. (2000) Epigenetic determinants of resistance to etoposide regulation of Bcl-X (L) and Bax by tumor microenvironmental factors. J. Natl Cancer Inst., 92 18-23.
    • (2000) J. Natl. Cancer Inst. , vol.92 , pp. 18-23
    • Taylor, S.T.1    Hickman, J.A.2    Dive, C.3
  • 26
    • 0035902141 scopus 로고    scopus 로고
    • The microenvironment of the tumour-host interface
    • Liotta,L.A. and Kohn,E.C. (2001) The microenvironment of the tumour-host interface. Nature, 411, 375-379.
    • (2001) Nature , vol.411 , pp. 375-379
    • Liotta, L.A.1    Kohn, E.C.2
  • 27
    • 0035170274 scopus 로고    scopus 로고
    • Apoptotic cell death in mammary adenocarcinoma cells is prevented by soluble factors present in the target organ of metastasis
    • Ladeda,V., Adam,A.P., Puricelli,L. and Bal de Kier Joffe,E. (2001) Apoptotic cell death in mammary adenocarcinoma cells is prevented by soluble factors present in the target organ of metastasis. Breast Cancer Res. Treat., 69, 39-51.
    • (2001) Breast Cancer Res. Treat. , vol.69 , pp. 39-51
    • Ladeda, V.1    Adam, A.P.2    Puricelli, L.3    Bal de Kier Joffe, E.4
  • 28
    • 0035902115 scopus 로고    scopus 로고
    • Proliferation, cell cycle and apoptosis in cancer
    • Evan,G.I. and Vousden,K.H. (2001) Proliferation, cell cycle and apoptosis in cancer. Nature, 411, 342-348.
    • (2001) Nature , vol.411 , pp. 342-348
    • Evan, G.I.1    Vousden, K.H.2
  • 29
    • 0032731892 scopus 로고    scopus 로고
    • Tumor invasion: Role of growth factor-induced cell motility
    • Wells,A. (2000) Tumor invasion: role of growth factor-induced cell motility. Adv. Cancer Res., 78, 31-101.
    • (2000) Adv. Cancer Res. , vol.78 , pp. 31-101
    • Wells, A.1
  • 31
    • 0032006059 scopus 로고    scopus 로고
    • Microtubules and actin filaments: Dynamic targets for cancer chemotherapy
    • Jordan,M.A. and Wilson,L. (1998) Microtubules and actin filaments: dynamic targets for cancer chemotherapy. Curr. Opin. Cell Biol., 10, 123-130.
    • (1998) Curr. Opin. Cell Biol. , vol.10 , pp. 123-130
    • Jordan, M.A.1    Wilson, L.2
  • 32
    • 0033760022 scopus 로고    scopus 로고
    • Chemotherapy of breast cancer: Are the taxanes going to change the natural history of breast cancer?
    • Nabholtz,J.M., Tonkin,K., Smylie,M., Au,H.J., Lindsay,M.A. and Mackey,J. (2000) Chemotherapy of breast cancer: are the taxanes going to change the natural history of breast cancer? Expert. Opin. Pharmacother., 1, 187-206.
    • (2000) Expert. Opin. Pharmacother. , vol.1 , pp. 187-206
    • Nabholtz, J.M.1    Tonkin, K.2    Smylie, M.3    Au, H.J.4    Lindsay, M.A.5    Mackey, J.6
  • 33
    • 0034061842 scopus 로고    scopus 로고
    • Docetaxel administered on a weekly basis for metastatic breast cancer
    • Burstein,H.J., Manola,J., Younger,J. et al. (2000) Docetaxel administered on a weekly basis for metastatic breast cancer. J. Clin. Oncol., 18, 1212-1219.
    • (2000) J. Clin. Oncol. , vol.18 , pp. 1212-1219
    • Burstein, H.J.1    Manola, J.2    Younger, J.3
  • 35
    • 0035900921 scopus 로고    scopus 로고
    • Adjuvant therapy for all patients with breast cancer?
    • Lippman,M.E. and Hayes,D.F. (2001) Adjuvant therapy for all patients with breast cancer? J. Natl Cancer Inst., 93, 80-82.
    • (2001) J. Natl. Cancer Inst. , vol.93 , pp. 80-82
    • Lippman, M.E.1    Hayes, D.F.2
  • 36
    • 0035893768 scopus 로고    scopus 로고
    • Autocrine production of interleukin 6 causes multidrug resistance in breast cancer cells
    • Conze,D., Weiss,L., Regen,P.S., Bhushan,A., Weaver,D., Johnson,P. and Rincon,M. (2001) Autocrine production of interleukin 6 causes multidrug resistance in breast cancer cells. Cancer Res., 61, 8851-8858.
    • (2001) Cancer Res. , vol.61 , pp. 8851-8858
    • Conze, D.1    Weiss, L.2    Regen, P.S.3    Bhushan, A.4    Weaver, D.5    Johnson, P.6    Rincon, M.7
  • 37
    • 0029110526 scopus 로고
    • Docetaxel (Taxotere): A review of preclinical and clinical experience. Part I: Preclinical experience
    • 339-355
    • Bissery,M.C., Nohynek,G., Sanderink,G.J. and Lavelle,F. (1995) Docetaxel (Taxotere): a review of preclinical and clinical experience. Part I: Preclinical experience. Anticancer Drugs, 6 339-355, 363-368.
    • (1995) Anticancer Drugs , vol.6 , pp. 363-368
    • Bissery, M.C.1    Nohynek, G.2    Sanderink, G.J.3    Lavelle, F.4
  • 38
    • 0027241246 scopus 로고
    • Antitumor activity of taxotere (RP 56976, NSC 628503), a new taxol analog, in experimental ovarian cancer
    • Boven,E., Venema-Gaberscek,E., Erkelens,C.A., Bissery,M.C. and Pinedo,H.M. (1993) Antitumor activity of taxotere (RP 56976, NSC 628503), a new taxol analog, in experimental ovarian cancer. Ann. Oncol., 4, 321-324.
    • (1993) Ann. Oncol. , vol.4 , pp. 321-324
    • Boven, E.1    Venema-Gaberscek, E.2    Erkelens, C.A.3    Bissery, M.C.4    Pinedo, H.M.5
  • 40
    • 0026425674 scopus 로고
    • Experimental antitumor activity of taxotere (RP 56976, NSC 628503), a taxol analogue
    • Bissery,M.C., Guenard,D., Gueritte-Voegelein,F. and Lavelle,F. (1991) Experimental antitumor activity of taxotere (RP 56976, NSC 628503), a taxol analogue. Cancer Res., 51, 4845-4852.
    • (1991) Cancer Res. , vol.51 , pp. 4845-4852
    • Bissery, M.C.1    Guenard, D.2    Gueritte-Voegelein, F.3    Lavelle, F.4
  • 41
    • 0033625203 scopus 로고    scopus 로고
    • Bcl-xL promotes metastasis of breast cancer cells by induction of cytokines resistance
    • Fernandez,Y., Espana,L., Manas,S., Fabra,A. and Sierra,A. (2000) Bcl-xL promotes metastasis of breast cancer cells by induction of cytokines resistance. Cell Death Differ., 7, 350-359.
    • (2000) Cell Death Differ. , vol.7 , pp. 350-359
    • Fernandez, Y.1    Espana, L.2    Manas, S.3    Fabra, A.4    Sierra, A.5
  • 42
    • 0038481970 scopus 로고    scopus 로고
    • The pathogenesis of cancer metastasis: The 'seed and soil' hypothesis revisited
    • Fidler,I.J. (2003) The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited. Nature Rev. Cancer, 3, 453-458.
    • (2003) Nature Rev. Cancer , vol.3 , pp. 453-458
    • Fidler, I.J.1
  • 43
    • 0037158692 scopus 로고    scopus 로고
    • A progression puzzle
    • Bernards,R. and Weinberg,R.A. (2002) A progression puzzle. Nature, 418, 823.
    • (2002) Nature , vol.418 , pp. 823
    • Bernards, R.1    Weinberg, R.A.2
  • 44
    • 0034602188 scopus 로고    scopus 로고
    • Role of BAX in the apoptotic response to anticancer agents
    • Zhang,L., Yu,J., Park,B.H., Kinzler,K.W. and Vogelstein,B. (2000) Role of BAX in the apoptotic response to anticancer agents. Science, 290, 989-992.
    • (2000) Science , vol.290 , pp. 989-992
    • Zhang, L.1    Yu, J.2    Park, B.H.3    Kinzler, K.W.4    Vogelstein, B.5
  • 45
    • 0030912390 scopus 로고    scopus 로고
    • Darwin's clinical relevance
    • Hellman,S. (1997) Darwin's clinical relevance. Cancer, 79, 2275-2281.
    • (1997) Cancer , vol.79 , pp. 2275-2281
    • Hellman, S.1
  • 46
    • 0037069929 scopus 로고    scopus 로고
    • Chemotherapy: Targeting the mitochondrial cell death pathway
    • Debatin,K.M., Poncet,D. and Kroemer,G. (2002) Chemotherapy: targeting the mitochondrial cell death pathway. Oncogene, 21, 8786-8803.
    • (2002) Oncogene , vol.21 , pp. 8786-8803
    • Debatin, K.M.1    Poncet, D.2    Kroemer, G.3
  • 47
    • 0036830417 scopus 로고    scopus 로고
    • Bcl-2/bcl-xL bispecific antisense treatment sensitizes breast carcinoma cells to doxorubicin, paclitaxel and cyclophosphamide
    • Simoes-Wust,A.P., Schurpf,T., Hall,J., Stahel,R.A. and Zangemeister-Wittke,U. (2002) Bcl-2/bcl-xL bispecific antisense treatment sensitizes breast carcinoma cells to doxorubicin, paclitaxel and cyclophosphamide. Breast Cancer Res. Treat., 76, 157-166.
    • (2002) Breast Cancer Res. Treat. , vol.76 , pp. 157-166
    • Simoes-Wust, A.P.1    Schurpf, T.2    Hall, J.3    Stahel, R.A.4    Zangemeister-Wittke, U.5
  • 49
    • 0033052436 scopus 로고    scopus 로고
    • Critical determinants of cancer metastasis: Rationale for therapy
    • Fidler,I.J. (1999) Critical determinants of cancer metastasis: rationale for therapy. Cancer Chemother. Pharmacol., 43, S3-10.
    • (1999) Cancer Chemother. Pharmacol. , vol.43
    • Fidler, I.J.1
  • 50
    • 0037226593 scopus 로고    scopus 로고
    • A molecular signature of metastasis in primary solid tumors
    • Ramaswamy,S., Ross,K.N., Lander,E.S. and Golub,T.R. (2003) A molecular signature of metastasis in primary solid tumors. Nature Genet., 33, 49-54.
    • (2003) Nature Genet. , vol.33 , pp. 49-54
    • Ramaswamy, S.1    Ross, K.N.2    Lander, E.S.3    Golub, T.R.4
  • 52
    • 0037137519 scopus 로고    scopus 로고
    • A gene-expression signature as a predictor of survival in breast cancer
    • van de Vijver,M.J., He,Y.D., van't Veer,L.J. et al. (2002) A gene-expression signature as a predictor of survival in breast cancer. N. Engl. J. Med., 347, 1999-2009.
    • (2002) N. Engl. J. Med. , vol.347 , pp. 1999-2009
    • van de Vijver, M.J.1    He, Y.D.2    van't Veer, L.J.3
  • 53
    • 18244409687 scopus 로고    scopus 로고
    • Gene expression profiling predicts clinical outcome of breast cancer
    • van't Veer,L.J., Dai,H., van de Vijver,M.J. et al. (2002) Gene expression profiling predicts clinical outcome of breast cancer. Nature, 415, 530-536.
    • (2002) Nature , vol.415 , pp. 530-536
    • van't Veer, L.J.1    Dai, H.2    van de Vijver, M.J.3


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