Crystal structure of severe acute respiratory syndrome coronavirus spike protein fusion core

Journal of Biological Chemistry

Volumn 279, Issue 47, 2004, Pages 49414-49419

  Xu, Yanhui ^a,b   Lou, Zhiyong ^a,b   Liu, Yiwei ^a,b   Pang, Hai ^a,b   Tien, Po ^d   Gao, George F ^c   Rao, Zihe ^a,b  

^a TSINGHUA UNIVERSITY   (China)

^b INSTITUTE OF BIOPHYSICS   (China)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d INSTITUTE OF MICROBIOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MEMBRANES; CRYSTAL STRUCTURE; CRYSTALLIZATION; DRUG PRODUCTS; HYDROPHOBICITY; LIVING SYSTEMS STUDIES; PROTEINS; VIRUSES;

CELLULAR MEMBRANES; HEPTAD REPEAT (HR) REGIONS; HYDROPHOBIC GROOVES; VIRAL FUSION PROTEINS;

DISEASES;

HYBRID PROTEIN; VIRUS PROTEIN;

ALPHA HELIX; ARTICLE; CELL MEMBRANE; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CORONAVIRUS; CORRELATION ANALYSIS; CRYSTAL STRUCTURE; CRYSTALLIZATION; GENETIC CONSERVATION; HYDROPHOBICITY; MOLECULAR BIOLOGY; MOLECULAR MECHANICS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DEGRADATION; STATISTICAL SIGNIFICANCE; STRUCTURE ANALYSIS; TANDEM REPEAT; VIRUS ENVELOPE;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANTIVIRAL AGENTS; CLONING, MOLECULAR; CRYSTALLOGRAPHY, X-RAY; DIMERIZATION; MEMBRANE GLYCOPROTEINS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PEPTIDES; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; SARS VIRUS; SEQUENCE HOMOLOGY, AMINO ACID; VIRAL ENVELOPE PROTEINS;

CORONAVIRUS; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; MURINE HEPATITIS VIRUS; RNA VIRUSES;

EID: 10344234242     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M408782200     Document Type: Article

References (51)

1. Tsang, K. W., Mok, T. Y., Wong, P. C., and Ooi, G. C. (2003) Respirology 8, 259-265
2. Poutanen, S. M., Low, D. E., Henry, B., Finkelstein, S., Rose, D., Green, K., Tellier, R., Draker, R., Adachi, D., Ayers, M., Chan, A. K., Skowronski, D. M., Salit, I., Simor, A. E., Slutsky, A. S., Doyle, P. W., Krajden, M., Petric, M., Brunham, R. C., and McGeer, A. J. (2003) N. Engl. J. Med. 348, 1995-2005
3. Drosten, C., Gunther, S., Preiser, W., van der Werf, S., Brodt, H. R., Becker, S., Rabenau, H., Panning, M., Kolesnikova, L., Fouchier, R. A., Berger, A., Burguiere, A. M., Cinatl, J., Eickmann, M., Escriou, N., Grywna, K., Kramme, S., Manuguerra, J. C., Muller, S., Rickerts, V., Sturmer, M., Vieth, S., Henk, H. D., Osterhaus, A. D., Schmitz, H., and Doerr, H. W. (2003) N. Engl. J. Med. 348, 1967-1976
4. Eickmann, M., Becker, S., Klenk, H. D., Doerr, H. W., Stadler, K., Censini, S., Guidotti, S., Masignani, V., Scarselli, M., Mora, M., Donati, C., Han, J. H., Song, H. C., Abrignani, S., Covacci, A., and Rappuoli, R. (2003) Science 302, 1504-1505
5. Stadler, K., Masignani, V., Eickmann, M., Becker, S., Abrignani, S., Klenk, H. D., and Rappuoli, R. (2003) Nat. Rev. Microbiol. 1, 209-218
6. Ksiazek, T. G., Erdman, D., Goldsmith, C. S., Zaki, S. R., Peret, T., Emery, S., Tong, S., Urbani, C., Comer, J. A., Lim, W., Rollin, P. E., Dowell, S. F., Ling, A. E., Humphrey, C. D., Shieh, W. J., Guarner, J., Paddock, C. D., Rota, P., Fields, B., DeRisi, J., Yang, J. Y., Cox, N., Hughes, J. M., LeDuc, J. W., Bellini, W. J., and Anderson, L. J. (2003) N. Engl. J. Med. 348, 1953-1966
7. Kuiken, T., Fouchier, R. A., Schutten, M., Rimmelzwaan, G. F., van Amerongen, G., van Riel, D., Laman, J. D., de Jong, T., van Doornum, G., Lim, W., Ling, A. E., Chan, P. K., Tam, J. S., Zambon, M. C., Gopal, R., Drosten, C., van der Werf, S., Escriou, N., Manuguerra, J. C., Stohr, K., Peiris, J. S., and Osterhaus, A. D. (2003) Lancet 362, 263-270
8. Peiris, J. S., Lai, S. T., Poon, L. L., Guan, Y., Yam, L. Y., Lim, W., Nicholls, J., Yee, W. K., Yan, W. W., Cheung, M. T., Cheng, V. C., Chan, K. H., Tsang, D. N., Yung, R. W., Ng, T. K., and Yuen, K. Y. (2003) Lancet 361, 1319-1325
9. Marra, M. A., Jones, S. J., Astell, C. R., Holt, R. A., Brooks-Wilson, A., Butterfield, Y. S., Khattra, J., Asano, J. K., Barber, S. A., Chan, S. Y., Cloutier, A., Coughlin, S. M., Freeman, D., Girn, N., Griffith, O. L., Leach, S. R., Mayo, M., McDonald, H., Montgomery, S. B., Pandoh, P. K., Petrescu, A. S., Robertson, A. G., Schein, J. E., Siddiqui, A., Smailus, D. E., Stott, J. M., Yang, G. S., Plummer, F., Andonov, A., Artsob, H., Bastien, N., Bernard, K., Booth, T. F., Bowness, D., Czub, M., Drebot, M., Fernando, L., Flick, R., Garbutt, M., Gray, M., Grolla, A., Jones, S., Feldmann, H., Meyers, A., Kabani, A., Li, Y., Normand, S., Stroher, U., Tipples, G. A., Tyler, S., Vogrig, R., Ward, D., Watson, B., Brunham, R. C., Krajden, M., Petric, M., Skowronski, D. M., Upton, C., and Roper, R. L. (2003) Science 300, 1399-1404
10. Rota, P. A., Oberste, M. S., Monroe, S. S., Nix, W. A., Campagnoli, R., Icenogle, J. P., Penaranda, S., Bankamp, B., Maher, K., Chen, M. H., Tong, S., Tamin, A., Lowe, L., Frace, M., DeRisi, J. L., Chen, Q., Wang, D., Erdman, D. D., Peret, T. C., Burns, C., Ksiazek, T. G., Rollin, P. E., Sanchez, A., Liffick, S., Holloway, B., Limor, J., McCaustland, K., Olsen-Rasmussen, M., Fouchier, R., Gunther, S., Osterhaus, A. D., Drosten, C., Pallansch, M. A., Anderson, L. J., and Bellini, W. J. (2003) Science 300, 1394-1399
11. Siddell, S., Wege, H., and Ter Meulen, V. (1983) J. Gen. Virol. 64, 761-776
12. Cavanagh, D. (1983) J. Gen. Virol. 64, 2577-2583
13. Gallagher, T. M., and Buchmeier, M. J. (2001) Virology 279, 371-374
14. Xu, Y., Liu, Y., Lou, Z., Qin, L., Li, X., Bai, Z., Pang, H., Tien, P., Gao, G. F., and Rao, Z. (2004) J. Biol. Chem. 279, 30514-30522
15. Bosch, B. J., van der Zee, R., de Haan, C. A., and Rottier, P. J. (2003) J. Virol. 77, 8801-8811
16. Eckert, D. M., and Kim, P. S. (2001) Annu. Rev. Biochem. 70, 777-810
17. Hernandez, L. D., Hoffman, L. R., Wolfsberg, T. G., and White, J. M. (1996) Annu. Rev. Cell Dev. Biol. 12, 627-661
18. Bullough, P. A., Hughson, F. M., Skehel, J. J., and Wiley, D. C. (1994) Nature 371, 37-43
19. Lu, M., Blacklow, S. C., and Kim, P. S. (1995) Nat. Struct. Biol. 2, 1075-1082
20. Weissenhorn, W., Dessen, A., Harrison, S. C., Skehel, J. J., and Wiley, D. C. (1997) Nature 387, 426-430
21. Chan, D. C., Fass, D., Berger, J. M., and Kim, P. S. (1997) Cell 89, 263-273
22. Tan, K., Liu, J., Wang, J., Shen, S., and Lu, M. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 12303-12308
23. Caffrey, M., Cai, M., Kaufman, J., Stahl, S. J., Wingfield, P. T., Covell, D. G., Gronenborn, A. M., and Clore, G. M. (1998) EMBO J. 17, 4572-4584
24. Weissenhorn, W., Carfi, A., Lee, K. H., Skehel, J. J., and Wiley, D. C. (1998) Mol. Cell 2, 605-616
25. Weissenhorn, W., Calder, L. J., Wharton, S. A., Skehel, J. J., and Wiley, D. C. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 6032-6036
26. Baker, K. A., Dutch, R. E., Lamb, R. A., and Jardetzky, T. S. (1999) Mol. Cell 3, 309-319
27. Delmas, B., and Laude, H. (1990) J. Virol. 64, 5367-5375
28. Bonavia, A., Zelus, B. D., Wentworth, D. E., Talbot, P. J., and Holmes, K. V. (2003) J. Virol. 77, 2530-2538
29. Taguchi, F. (1995) J. Virol. 69, 7260-7263
30. Chan, D. C., and Kim, P. S. (1998) Cell 93, 681-684
31. Ingallinella, P., Bianchi, E., Finotto, M., Cantoni, G., Eckert, D. M., Supekar, V. M., Bruckmann, C., Carfi, A., and Pessi, A. (2004) Proc. Natl. Acad. Sci. U. S. A. 101, 8709-8714
32. Bosch, B. J., Martina, B. E., Van Der Zee, R., Lepault, J., Haijema, B. J., Versluis, C., Heck, A. J., De Groot, R., Osterhaus, A. D., and Rottier, P. J. (2004) Proc. Natl Acad. Sci. U. S. A. 101, 8455-8460
33. Yuan, K., Yi, L., Chen, J., Qu, X., Qing, T., Eao, X., Jiang, P., Hu, J., Xiong, Z., Nie, Y., Shi, X., Wang, W., Ling, C., Yin, X., Fan, K., Lai, L., Ding, M., and Deng, H. (2004) Biochem. Biophys. Res. Commun. 319, 746-752
34. Zhu, J., Xiao, G., Xu, Y., Yuan, F., Zheng, C., Liu, Y., Yan, H., Cole, D. K., Bell, J. I., Rao, Z., Tien, P., and Gao, G. F. (2004) Biochem. Biophys. Res. Commun. 319, 283-288
35. Liu, S., Xiao, G., Chen, Y., He, Y., Niu, J., Escalante, C. R., Xiong, H., Farmar, J., Debnath, A. K., Tien, P., and Jiang, S. (2004) Lancet 363, 938-947
36. Tripet, B., Howard, M. W., Jobling, M., Holmes, R. K., Holmes, K. V., and Hodges, R. S. (2004) J. Biol. Chem. 279, 20836-20849
37. Singh, M., Berger, B., and Kim, P. S. (1999) J. Mol. Biol. 290, 1031-1041
38. Otwinowski, Z., and Minor, W. (1997) Methods Enzymol. 276, 307-326
39. Brunger, A. T., Adams, P. D., Clore, G. M., DeLano, W. L., Gros, P., Grosse-Kunstleve, R. W., Jiang, J. S., Kuszewski, J., Nilges, M., Pannu, N. S., Read, R. J., Rice, L. M., Simonson, T., and Warren, G. L. (1998) Acta Crystallogr. D Biol. Crystallogr. 54, 905-921
40. Jones, T. A., Zou, J. Y., Cowan, S. W., and Kjeldgaard, M. (1991) Acta Crystallogr. A. 47, 110-119
41. Laskowski, R. A., MacArthur, M. W., Moss, D. S., and Thornton, J. M. (1993) J. Appl. Crystallogr. 26, 283-291
42. Nicholls, A., Sharp, K. A., and Honig, B. (1991) Proteins 11, 281-296
43. Guex, N., and Peitsch, M. C. (1997) Electrophoresis 18, 2714-2723
44. Kraulis, P. J. (1991) J. Appl. Crystallogr. 24, 946-950
45. Eckert, D. M., and Kim, P. S. (2001) Proc. Natl. Acad. Sci. U. S. A. 98, 11187-11192
46. Root, M. J., Kay, M. S., and Kim, P. S. (2001) Science 291, 884-888
47. Eckert, D. M., Malashkevich, V. N., Hong, L. H., Carr, P. A., and Kim, P. S. (1999) Cell 99, 103-115
48. Wild, C. T., Shugars, D. C., Greenwell, T. K., McDanal, C. B., and Matthews, T. J. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 9770-9774
49. Kilby, J. M., Hopkins, S., Venetta, T. M., DiMassimo, B., Cloud, G. A., Lee, J. Y., Alldredge, L., Hunter, E., Lambert, D., Bolognesi, D., Matthews, T., Johnson, M. R., Nowak, M. A., Shaw, G. M., and Saag, M. S. (1998) Nat. Med. 4, 1302-1307
50. Imai, M., Okada, N., and Okada, H. (2000) Microbiol. Immunol. 44, 205-212
51. Watanabe, S., Takada, A., Watanabe, T., Ito, H., Kida, H., and Kawaoka, Y. (2000) J. Virol. 74, 10194-10201