Noc3p, a bHLH protein, plays an integral role in the initiation of DNA replication in budding yeast

Cell

Volumn 109, Issue 7, 2002, Pages 849-860

  Zhang, Yuexuan ^a   Yu, Zhiling ^a   Fu, Xinrong ^a   Liang, Chun ^a  

^a HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; BHLH PROTEIN; NUCLEOLAR COMPLEX ASSOCIATED PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BUDDING; CELL CYCLE; CHROMATIN; CONTROLLED STUDY; DNA REPLICATION; EUKARYOTIC CELL; GENETIC SCREENING; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN INTERACTION; YEAST;

BACTERIA (MICROORGANISMS); EUKARYOTA; SACCHAROMYCETALES;

EID: 0037188889     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(02)00805-X     Document Type: Article

References (55)

1. Components and dynamics of DNA replication complexes in S. cerevisiae: Redistribution of MCM proteins and Cdc45p during S phase
2. ATP-dependent recognition of eukaryotic origins of DNA replication by a multiprotein complex
3. Yeast origin recognition complex functions in transcription silencing and DNA replication
4. Dual functions of CDC6: A yeast protein required for DNA replication also inhibits nuclear division
5. Cdc6 cooperates with Sic1 and Hct1 to inactivate mitotic cyclin-dependent kinases
6. Purification of an MCM-containing complex as a component of the DNA replication licensing system
7. An essential role for the Cdc6 protein in forming the pre-replicative complexes of budding yeast
8. The Xenopus Cdc6 protein is essential for the initiation of a single round of DNA replication in cell-free extracts
9. S-phase-promoting cyclin-dependent kinases prevent re-replication by inhibiting the transition of replication origins to a pre-replicative state
10. Characterization of Cdc47p-minichromosome maintenance complexes in Saccharomyces cerevisiae: Identification of Cdc45p as a subunit
11. Two steps in the assembly of complexes at yeast replication origins in vivo
12. Heat-inducible degron: A method for constructing temperature-sensitive mutants
13. Cdc6p-dependent loading of Mcm proteins onto pre-replicative chromatin in budding yeast
14. The cyclin-dependent kinase Cdc28p regulates distinct modes of Cdc6p proteolysis during the budding yeast cell cycle
15. Origin recognition complex (ORC) in transcriptional silencing and DNA replication in S. cerevisiae
16. The origin recognition complex has essential functions in transcriptional silencing and chromosomal replication
17. Conserved initiator proteins in eukaryotes
18. Redundant control of rereplication in fission yeast
19. A group of interacting yeast DNA replication genes
20. Addition of extra origins of replication to a minichromosome suppresses its mitotic loss in cdc6 and cdc14 mutants of Saccharomyces cerevisiae
21. Mcm10 and the MCM2-7 complex interact to initiate DNA synthesis and to release replication factors from origins
22. Rum1 and Cdc18 link inhibition of cyclin-dependent kinase to the initiation of DNA replication in Schizosaccharomyces pombe
23. Physical interactions among Mcm proteins and effects of Mcm dosage on DNA replication in Saccharomyces cerevisiae
24. Persistent initiation of DNA replication and chromatin-bound MCM proteins during the cell cycle in cdc6 mutants
25. ORC and Cdc6p interact and determine the frequency of initiation of DNA replication in the genome
26. Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae
27. The origin recognition complex in silencing, cell cycle progression, and DNA replication
28. MCM3 complex required for cell cycle regulation of DNA replication in vertebrate cells
29. XCDT1 is required for the assembly of pre-replicative complexes in Xenopus laevis
30. Helix-loop-helix proteins: Regulators of transcription in eucaryotic organisms
31. A lesion in the DNA replication initiation factor Mcm10 induces pausing of elongation forks through chromosomal replication origins in Saccharomyces cerevisiae
32. Maturation and intranuclear transport of pre-ribosomes requires Noc proteins
33. Orp1, a member of the Cdc18/Cdc6 family of S-phase regulators, is homologous to a component of the origin recognition complex
34. Cyclin-dependent kinases prevent DNA re-replication through multiple mechanisms
35. The Cdt1 protein is required to license DNA for replication in fission yeast
36. The human licensing factor for DNA replication Cdt1 accumulates in G1 and is destabilized after initiation of S-phase
37. CDC45 is required in conjunction with CDC7/DBF4 to trigger the initiation of DNA replication
38. Survey and summary: Saccharomyces cerevisiae basic helix-loop-helix proteins regulate diverse biological processes
39. The human homolog of Saccharomyces cerevisiae CDC45
40. Repression of origin assembly in metaphase depends on inhibition of RLF-B/Cdt1 by geminin
41. Interdependent nuclear accumulation of budding yeast Cdt1 and Mcm2-7 during G1 phase
42. Loading of an Mcm protein onto DNA replication origins is regulated by Cdc6p and CDKs
43. The RLF-M component of the replication licensing system forms complexes containing all six MCM/P1 polypeptides
44. Cdc7p-Dbf4p kinase binds to chromatin during S phase and is regulated by both the APC and the RAD53 checkpoint pathway
45. The Cdc6p nucleotide-binding motif is required for loading mcm proteins onto chromatin
46. Binding of cyclin-dependent kinases to ORC and Cdc6p regulates the chromosome replication cycle
47. A human protein related to yeast Cdc6p
48. Drosophila double parked: A conserved, essential replication protein that colocalizes with the origin recognition complex and links DNA replication with mitosis and the down-regulation of S phase transcripts
49. Inhibition of eukaryotic DNA replication by geminin binding to Cdt1
50. Mcm2 and Mcm3, two proteins important for ARS activity, are related in structure and function
51. Cell cycle-regulated nuclear localization of MCM2 and MCM3, which are required for the initiation of DNA synthesis at chromosomal replication origins in yeast
52. Cdc6 is regulated by E2F and is essential for DNA replication in mammalian cells
53. MCM proteins are associated with RNA polymerase II holoenzyme
54. Formation of a preinitiation complex by S-phase cyclin CDK-dependent loading of Cdc45p onto chromatin
55. CDC45, a novel yeast gene that functions with the origin recognition complex and Mcm proteins in initiation of DNA replication