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Volumn 57, Issue 12, 2004, Pages 1292-1298

The perforin mediated apoptotic pathway in lung injury and fibrosis

Author keywords

[No Author keywords available]

Indexed keywords

BLEOMYCIN; GRANZYME B; PERFORIN;

EID: 10044279487     PISSN: 00219746     EISSN: None     Source Type: Journal    
DOI: 10.1136/jcp.2003.015495     Document Type: Article
Times cited : (31)

References (34)
  • 1
    • 0027316973 scopus 로고
    • Role of mesenchymal cell death in lung remodeling after injury
    • Polnovsky VA, Chen B, Henke C, et al. Role of mesenchymal cell death in lung remodeling after injury. J Clin Invest 1993;92:388-97.
    • (1993) J Clin Invest , vol.92 , pp. 388-397
    • Polnovsky, V.A.1    Chen, B.2    Henke, C.3
  • 2
    • 0035143422 scopus 로고    scopus 로고
    • Fas (CD95) induces alveolar epithelial cell apoptosis in vivo: Implications for acute pulmonary inflammation
    • Matute-Bello G, Winn RK, Jonas M, et al. Fas (CD95) induces alveolar epithelial cell apoptosis in vivo: implications for acute pulmonary inflammation. Am J Pathol 2001;158:153-61.
    • (2001) Am J Pathol , vol.158 , pp. 153-161
    • Matute-Bello, G.1    Winn, R.K.2    Jonas, M.3
  • 3
    • 0034890052 scopus 로고    scopus 로고
    • Recombinant human Fas ligand induces alveolar epithelial cell apoptosis and lung injury in rabbits
    • Matute-Bello G, Liles WC, Frevert CW, et al. Recombinant human Fas ligand induces alveolar epithelial cell apoptosis and lung injury in rabbits. Am J Physiol Lung Cell Mol Physiol 2001;281:L328-35.
    • (2001) Am J Physiol Lung Cell Mol Physiol , vol.281
    • Matute-Bello, G.1    Liles, W.C.2    Frevert, C.W.3
  • 4
    • 0031230494 scopus 로고    scopus 로고
    • Induction of apoptosis and pulmonary fibrosis in mice in response to ligation of Fas antigen
    • Hagimoto N, Kuwano K, Miyazaki H, et al. Induction of apoptosis and pulmonary fibrosis in mice in response to ligation of Fas antigen. Am J Respir Cell Mol Biol 1997;17:272-8.
    • (1997) Am J Respir Cell Mol Biol , vol.17 , pp. 272-278
    • Hagimoto, N.1    Kuwano, K.2    Miyazaki, H.3
  • 5
    • 0028110928 scopus 로고
    • Fas and perform pathways as major mechanisms of T cell-mediated cytotoxicity
    • Kägi D, Vignaux F, Ledermann B, et al. Fas and perform pathways as major mechanisms of T cell-mediated cytotoxicity. Science 1994;265:528-30.
    • (1994) Science , vol.265 , pp. 528-530
    • Kägi, D.1    Vignaux, F.2    Ledermann, B.3
  • 6
    • 0022497854 scopus 로고
    • Purification and characterization of a cytolytic pore-forming protein from granules of cloned lymphocytes with natural killer activity
    • Young JD, Hengartner H, Podack ER, et al. Purification and characterization of a cytolytic pore-forming protein from granules of cloned lymphocytes with natural killer activity. Cell 1986;44:849-59.
    • (1986) Cell , vol.44 , pp. 849-859
    • Young, J.D.1    Hengartner, H.2    Podack, E.R.3
  • 7
    • 0023813169 scopus 로고
    • Structure and function of human perforin
    • Lichtenheld MG, Olsen KJ, Lu P. Structure and function of human perforin. Nature 1988;335:448-51.
    • (1988) Nature , vol.335 , pp. 448-451
    • Lichtenheld, M.G.1    Olsen, K.J.2    Lu, P.3
  • 8
    • 0023645045 scopus 로고
    • A family of serine esterases in lytic granules of cytolytic T lymphocytes
    • Masson D, Tschopp J. A family of serine esterases in lytic granules of cytolytic T lymphocytes. Cell 1987;49:679-85.
    • (1987) Cell , vol.49 , pp. 679-685
    • Masson, D.1    Tschopp, J.2
  • 9
    • 0023688825 scopus 로고
    • Molecular cloning of an inducible serine esterase gene from human cytotoxic lymphocytes
    • Trapani JA, Klein JL, White PC, et al. Molecular cloning of an inducible serine esterase gene from human cytotoxic lymphocytes. Proc Natl Acad Sci U S A 1988;85:6924-8.
    • (1988) Proc Natl Acad Sci U S A , vol.85 , pp. 6924-6928
    • Trapani, J.A.1    Klein, J.L.2    White, P.C.3
  • 10
    • 0024430418 scopus 로고
    • Purified perform induces target cell lysis but not DNA fragmentation
    • Duke RC, Persechini PM, Chang S, et al. Purified perform induces target cell lysis but not DNA fragmentation. J Exp Med 1989;170:1451-6.
    • (1989) J Exp Med , vol.170 , pp. 1451-1456
    • Duke, R.C.1    Persechini, P.M.2    Chang, S.3
  • 11
    • 0030892138 scopus 로고    scopus 로고
    • Granzyme B (GraB) autonomously crosses the cell membrane and perform initiates apoptosis and GraB nuclear localization
    • Shi L, Mai S, Israels S, et al. Granzyme B (GraB) autonomously crosses the cell membrane and perform initiates apoptosis and GraB nuclear localization. J Exp Med 1997;185:855-66.
    • (1997) J Exp Med , vol.185 , pp. 855-866
    • Shi, L.1    Mai, S.2    Israels, S.3
  • 12
    • 0028219791 scopus 로고
    • Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice
    • Kägi D, Ledermann B, Burki K, et al. Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice. Nature 1994;369:31-7.
    • (1994) Nature , vol.369 , pp. 31-37
    • Kägi, D.1    Ledermann, B.2    Burki, K.3
  • 13
    • 10544252275 scopus 로고    scopus 로고
    • New paradigm for lymphocyte granule-mediated cytotoxicity. Target cells bind and internalize granzyme B, but an endosomolytic agent is necessary for cytosolic delivery and subsequent apoptosis
    • Froelich CJ, Orth K, Turbov J, et al. New paradigm for lymphocyte granule-mediated cytotoxicity. Target cells bind and internalize granzyme B, but an endosomolytic agent is necessary for cytosolic delivery and subsequent apoptosis. J Biol Chem 1996;271:29073-9.
    • (1996) J Biol Chem , vol.271 , pp. 29073-29079
    • Froelich, C.J.1    Orth, K.2    Turbov, J.3
  • 14
    • 0031793774 scopus 로고    scopus 로고
    • Modes of epithelial cell death and repair in Sjogren's syndrome (SS)
    • Polihronis M, Tapinos NI, Theocharis SE, et al. Modes of epithelial cell death and repair in Sjogren's syndrome (SS). Clin Exp Immunol 1998;114:485-90.
    • (1998) Clin Exp Immunol , vol.114 , pp. 485-490
    • Polihronis, M.1    Tapinos, N.I.2    Theocharis, S.E.3
  • 15
    • 1842289172 scopus 로고    scopus 로고
    • Reduced incidence and delayed onset of diabetes in perforin-deficient nonobese diabetic mice
    • Kägi D, Odermatt B, Seiler P, et al. Reduced incidence and delayed onset of diabetes in perforin-deficient nonobese diabetic mice. J Exp Med 1997;186:989-97.
    • (1997) J Exp Med , vol.186 , pp. 989-997
    • Kägi, D.1    Odermatt, B.2    Seiler, P.3
  • 16
    • 0030050453 scopus 로고    scopus 로고
    • Cytotoxic T cells deficient in bath functional fas ligand and perform show residual cytolytic activity yet lose their capacity to induce lethal acute graft-versus-host disease
    • Braun MY, Lowin B, French L, et al. Cytotoxic T cells deficient in bath functional fas ligand and perform show residual cytolytic activity yet lose their capacity to induce lethal acute graft-versus-host disease. J Exp Med 1996;183:657-61.
    • (1996) J Exp Med , vol.183 , pp. 657-661
    • Braun, M.Y.1    Lowin, B.2    French, L.3
  • 17
    • 0033966777 scopus 로고    scopus 로고
    • Upregulation of two death pathways of perforin/granzyme and FasL/Fas in septic acute respiratory distress syndrome
    • Hashimoto S, Kobayashi A, Kooguchi K, et al. Upregulation of two death pathways of perforin/granzyme and FasL/Fas in septic acute respiratory distress syndrome. Am J Respir Crit Care Med 2000;161:237-43.
    • (2000) Am J Respir Crit Care Med , vol.161 , pp. 237-243
    • Hashimoto, S.1    Kobayashi, A.2    Kooguchi, K.3
  • 18
    • 8944230654 scopus 로고    scopus 로고
    • Differential expression of perform in muscle-infiltrating T cells in polymyositis and dermatomyositis
    • Goebels N, Michaelis D, Engelhardt M, et al. Differential expression of perform in muscle-infiltrating T cells in polymyositis and dermatomyositis. J Clin Invest 1996;97:2905-10.
    • (1996) J Clin Invest , vol.97 , pp. 2905-2910
    • Goebels, N.1    Michaelis, D.2    Engelhardt, M.3
  • 19
    • 0030215822 scopus 로고    scopus 로고
    • P21Waf1/Cip1/Sdi1 and p53 expression in association with DNA strand breaks in idiopathic pulmonary fibrosis
    • Kuwano K, Kunitake R, Kawasaki M, et al. P21Waf1/Cip1/Sdi1 and p53 expression in association with DNA strand breaks in idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 1996;154:477-83.
    • (1996) Am J Respir Crit Care Med , vol.154 , pp. 477-483
    • Kuwano, K.1    Kunitake, R.2    Kawasaki, M.3
  • 20
    • 0032622244 scopus 로고    scopus 로고
    • The involvement of Fas-Fas ligand pathway in fibrosing lung diseases
    • Kuwana K, Miyazaki H, Hagimoto N, et al. The involvement of Fas-Fas ligand pathway in fibrosing lung diseases. Am J Respir Cell Mol Biol 1999;20:53-60.
    • (1999) Am J Respir Cell Mol Biol , vol.20 , pp. 53-60
    • Kuwana, K.1    Miyazaki, H.2    Hagimoto, N.3
  • 21
    • 0032717522 scopus 로고    scopus 로고
    • Essential roles of the Fas-Fas ligand pathway in the development of pulmonary fibrosis
    • Kuwano K, Hagimoto N, Kawasaki M, et al. Essential roles of the Fas-Fas ligand pathway in the development of pulmonary fibrosis. J Clin Invest 1999;104:13-19.
    • (1999) J Clin Invest , vol.104 , pp. 13-19
    • Kuwano, K.1    Hagimoto, N.2    Kawasaki, M.3
  • 22
    • 0037106266 scopus 로고    scopus 로고
    • Bleomycin sensitivity of mice expressing dominant-negative p53 in the lung epithelium
    • Ghosh S, Mendoza T, Ortiz LA, et al. Bleomycin sensitivity of mice expressing dominant-negative p53 in the lung epithelium. Am J Respir Crit Care Med 2002;166:890-7.
    • (2002) Am J Respir Crit Care Med , vol.166 , pp. 890-897
    • Ghosh, S.1    Mendoza, T.2    Ortiz, L.A.3
  • 23
    • 0033862955 scopus 로고    scopus 로고
    • Abrogation of bleomycin-induced epithelial apoptosis and lung fibrosis by captopril or by a caspase inhibitor
    • Wang R, Ibarra-Sunga O, Verlinski L, et al. Abrogation of bleomycin-induced epithelial apoptosis and lung fibrosis by captopril or by a caspase inhibitor. Am J Physiol lung Cell Mol Physiol 2000;279:L143-51.
    • (2000) Am J Physiol Lung Cell Mol Physiol , vol.279
    • Wang, R.1    Ibarra-Sunga, O.2    Verlinski, L.3
  • 24
    • 0030638505 scopus 로고    scopus 로고
    • Apoptosis and expression of Fas/Fas ligand mRNA in bleomycin-induced pulmonary fibrosis in mice
    • Hagimoto N, Kuwano K, Nomoto Y, et al. Apoptosis and expression of Fas/Fas ligand mRNA in bleomycin-induced pulmonary fibrosis in mice. Am J Respir Cell Mol Biol 1997;16:91-101.
    • (1997) Am J Respir Cell Mol Biol , vol.16 , pp. 91-101
    • Hagimoto, N.1    Kuwano, K.2    Nomoto, Y.3
  • 25
    • 0034011982 scopus 로고    scopus 로고
    • Idiopathic pulmonary fibrosis: Diagnosis and treatment. International consensus statement
    • American Thoracic Society, Idiopathic pulmonary fibrosis: diagnosis and treatment. International consensus statement. Am J Respir Crit Care Med 2000;16:646-64.
    • (2000) Am J Respir Crit Care Med , vol.16 , pp. 646-664
  • 26
    • 0030638505 scopus 로고    scopus 로고
    • Apoptosis and expression of Fas/Fas ligand mRNA in bleomycin-induced pulmonary fibrosis in mice
    • Hagimoto N, Kuwano K, Nomoto Y, et al. Apoptosis and expression of Fas/Fas ligand mRNA in bleomycin-induced pulmonary fibrosis in mice. Am J Respir Cell Mol Biol 1997;16:91-101.
    • (1997) Am J Respir Cell Mol Biol , vol.16 , pp. 91-101
    • Hagimoto, N.1    Kuwano, K.2    Nomoto, Y.3
  • 27
    • 0032437815 scopus 로고    scopus 로고
    • Alveolar epithelial cell death adjacent to underlying myofibroblasts in advanced fibrotic human lung
    • Uhal BD, Joshi I, Hughes WF, et al. Alveolar epithelial cell death adjacent to underlying myofibroblasts in advanced fibrotic human lung. Am J Physiol 1998;275:L1192-9.
    • (1998) Am J Physiol , vol.275
    • Uhal, B.D.1    Joshi, I.2    Hughes, W.F.3
  • 28
    • 0035141395 scopus 로고    scopus 로고
    • Evidence of type II pneumocyte apoptosis in the pathogenesis of idiopathic pulmonary fibrosis (IFP)/usual interstitial pneumonia (UIP)
    • Barbas-Filho JV, Ferreira MA, Sesso A, et al. Evidence of type II pneumocyte apoptosis in the pathogenesis of idiopathic pulmonary fibrosis (IFP)/usual interstitial pneumonia (UIP). J Clin Pathol 2001;54:132-8.
    • (2001) J Clin Pathol , vol.54 , pp. 132-138
    • Barbas-Filho, J.V.1    Ferreira, M.A.2    Sesso, A.3
  • 29
    • 12244286790 scopus 로고    scopus 로고
    • Oxidative stress in lung epithelial cells from patients with idiopathic interstitial pneumonias
    • Kuwano K, Nakashima N, Inoshima I, et al. Oxidative stress in lung epithelial cells from patients with idiopathic interstitial pneumonias. Eur Respir J 2003;21:232-40.
    • (2003) Eur Respir J , vol.21 , pp. 232-240
    • Kuwano, K.1    Nakashima, N.2    Inoshima, I.3
  • 30
    • 0033862955 scopus 로고    scopus 로고
    • Abrogation of bleomycin-induced epithelial apaptosis and lung fibrosis by captopril or by a caspase inhibitor
    • Wang R, Ibarra-Sunga O, Verlinski L, et al. Abrogation of bleomycin-induced epithelial apaptosis and lung fibrosis by captopril or by a caspase inhibitor. Am J Physiol Lung Cell Mol Physiol 2000;279:L143-51.
    • (2000) Am J Physiol Lung Cell Mol Physiol , vol.279
    • Wang, R.1    Ibarra-Sunga, O.2    Verlinski, L.3
  • 31
    • 0036310801 scopus 로고    scopus 로고
    • A p38 MAPK inhibitor, FR-167653, ameliorates murine bleomycin-induced pulmonary fibrosis
    • Matsuoka H, Arai T, Mori M, et al. A p38 MAPK inhibitor, FR-167653, ameliorates murine bleomycin-induced pulmonary fibrosis. Am J Physiol lung Cell Mol Physiol 2002;283:L103-12.
    • (2002) Am J Physiol Lung Cell Mol Physiol , vol.283
    • Matsuoka, H.1    Arai, T.2    Mori, M.3
  • 32
    • 0036431777 scopus 로고    scopus 로고
    • Adenovirus-mediated transfer and overexpression of heme oxygen 1 cDNA in lung prevents bleomycin-induced pulmonary fibrosis via a Fas-Fas ligand-independent pathway
    • Tsuburai T, Suzuki M, Nagashima Y, et al. Adenovirus-mediated transfer and overexpression of heme oxygen 1 cDNA in lung prevents bleomycin-induced pulmonary fibrosis via a Fas-Fas ligand-independent pathway. Hum Gene Ther 2002;13:1945-60.
    • (2002) Hum Gene Ther , vol.13 , pp. 1945-1960
    • Tsuburai, T.1    Suzuki, M.2    Nagashima, Y.3
  • 33
    • 0034694083 scopus 로고    scopus 로고
    • Granzyme B-mediated cytochrome c release is regulated by the Bcl-2 family members bid and Bax
    • Heibein JA, Goping IS, Barry M, et al. Granzyme B-mediated cytochrome c release is regulated by the Bcl-2 family members bid and Bax. J Exp Med 2000;192:1391-402.
    • (2000) J Exp Med , vol.192 , pp. 1391-1402
    • Heibein, J.A.1    Goping, I.S.2    Barry, M.3
  • 34
    • 0035910057 scopus 로고    scopus 로고
    • Granzyme B can cause mitochondrial depolarization and cell death in the absence of BID, BAX, and BAK
    • Thomas DA, Scorrano L, Putcha GV, et al. Granzyme B can cause mitochondrial depolarization and cell death in the absence of BID, BAX, and BAK. Proc Natl Acad Sci U S A 2001;98:14985-90.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 14985-14990
    • Thomas, D.A.1    Scorrano, L.2    Putcha, G.V.3


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