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Volumn 206, Issue 1, 2005, Pages 91-109

Gene expression changes induced by estrogen and selective estrogen receptor modulators in primary-cultured human endometrial cells: Signals that distinguish the human carcinogen tamoxifen

Author keywords

Arrays; Endometrial cancer; Endometrium; Estrogen; Raloxifene; SERM; Tamoxifen

Indexed keywords

DIHYDROFOLATE REDUCTASE; ESTRADIOL; ESTROGEN; MYC PROTEIN; RALOXIFENE; SELECTIVE ESTROGEN RECEPTOR MODULATOR; TAMOXIFEN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR E2F1;

EID: 10044264513     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2004.07.005     Document Type: Article
Times cited : (27)

References (66)
  • 1
    • 34547393844 scopus 로고    scopus 로고
    • IARC on tamoxifen
    • IARC on tamoxifen, 1996. Environ. Health Perspect. 104, 688.
    • (1996) Environ. Health Perspect. , vol.104 , pp. 688
  • 2
    • 0019852254 scopus 로고
    • Estrogen-like action of tamoxifen on vaginal epithelium in breast cancer patients
    • F. Boccardo, P. Bruzzi, A. Rubagotti, G.U. Nicolo, and R. Rosso Estrogen-like action of tamoxifen on vaginal epithelium in breast cancer patients Oncology 38 1981 281 285
    • (1981) Oncology , vol.38 , pp. 281-285
    • Boccardo, F.1    Bruzzi, P.2    Rubagotti, A.3    Nicolo, G.U.4    Rosso, R.5
  • 3
    • 0030942879 scopus 로고    scopus 로고
    • Expression and hormone regulation of Wnt2, 3, 4, 5a, 7a, 7b and 10b in normal human endometrium and endometrial carcinoma
    • T.D. Bui, L. Zhang, M.C. Rees, R. Bicknell, and A.L. Harris Expression and hormone regulation of Wnt2, 3, 4, 5a, 7a, 7b and 10b in normal human endometrium and endometrial carcinoma Br. J. Cancer 75 1997 1131 1136
    • (1997) Br. J. Cancer , vol.75 , pp. 1131-1136
    • Bui, T.D.1    Zhang, L.2    Rees, M.C.3    Bicknell, R.4    Harris, A.L.5
  • 4
    • 0031772702 scopus 로고    scopus 로고
    • Mechanisms of action of antiestrogens: Relevance to clinical benefits and risks
    • P.L. Carmichael Mechanisms of action of antiestrogens: relevance to clinical benefits and risks Cancer Invest. 16 1998 604 611
    • (1998) Cancer Invest. , vol.16 , pp. 604-611
    • Carmichael, P.L.1
  • 9
    • 0035903160 scopus 로고    scopus 로고
    • Estrogen regulation of cyclin D1 gene expression in ZR-75 breast cancer cells involves multiple enhancer elements
    • E. Castro-Rivera, I. Samudio, and S. Safe Estrogen regulation of cyclin D1 gene expression in ZR-75 breast cancer cells involves multiple enhancer elements J. Biol. Chem. 276 2001 30853 30861
    • (2001) J. Biol. Chem. , vol.276 , pp. 30853-30861
    • Castro-Rivera, E.1    Samudio, I.2    Safe, S.3
  • 13
    • 0034037212 scopus 로고    scopus 로고
    • Modulation of endometrial steroid receptors and growth regulatory genes by tamoxifen
    • J. Elkas, A. Armstrong, J. Pohl, F. Cuttitta, A. Martinez, and K. Gray Modulation of endometrial steroid receptors and growth regulatory genes by tamoxifen Obstet. Gynecol. 95 2000 697 703
    • (2000) Obstet. Gynecol. , vol.95 , pp. 697-703
    • Elkas, J.1    Armstrong, A.2    Pohl, J.3    Cuttitta, F.4    Martinez, A.5    Gray, K.6
  • 15
    • 0028208456 scopus 로고
    • Endometrial cancer in tamoxifen-treated breast cancer patients: Findings from the National Surgical Adjuvant Breast and Bowel Project (NSABP) B-14
    • B. Fisher, J.P. Costantino, C.K. Redmond, E.R. Fisher, D.L. Wickerham, and W.M. Cronin Endometrial cancer in tamoxifen-treated breast cancer patients: findings from the National Surgical Adjuvant Breast and Bowel Project (NSABP) B-14 J. Natl. Cancer Inst. 86 1994 527 537
    • (1994) J. Natl. Cancer Inst. , vol.86 , pp. 527-537
    • Fisher, B.1    Costantino, J.P.2    Redmond, C.K.3    Fisher, E.R.4    Wickerham, D.L.5    Cronin, W.M.6
  • 17
    • 0028905332 scopus 로고
    • Effects of estradiol and testosterone on the synthesis, expression and degradation of androgen receptor in human uterine endometrial fibroblasts
    • J. Fujimoto, M. Nishigaki, M. Hori, S. Ichigo, S. Morishita, and T. Tamaya Effects of estradiol and testosterone on the synthesis, expression and degradation of androgen receptor in human uterine endometrial fibroblasts J. Biomed. Sci. 2 1995 160 165
    • (1995) J. Biomed. Sci. , vol.2 , pp. 160-165
    • Fujimoto, J.1    Nishigaki, M.2    Hori, M.3    Ichigo, S.4    Morishita, S.5    Tamaya, T.6
  • 18
    • 0033677086 scopus 로고    scopus 로고
    • PDZK1 and GREB1 are estrogen-regulated genes expressed in hormone-responsive breast cancer
    • M.G. Ghosh, D.A. Thompson, and R.J. Weigel PDZK1 and GREB1 are estrogen-regulated genes expressed in hormone-responsive breast cancer Cancer Res. 60 2000 6367 6375
    • (2000) Cancer Res. , vol.60 , pp. 6367-6375
    • Ghosh, M.G.1    Thompson, D.A.2    Weigel, R.J.3
  • 19
    • 0033753493 scopus 로고    scopus 로고
    • Update on raloxifene to prevent endometrial-breast cancer
    • S.R. Goldstein Update on raloxifene to prevent endometrial-breast cancer Eur. J. Cancer 36 Suppl. 4 2000 54 56
    • (2000) Eur. J. Cancer , vol.36 , Issue.4 , pp. 54-56
    • Goldstein, S.R.1
  • 20
    • 0028363984 scopus 로고
    • Hormonal regulation of proliferation and transforming growth factors gene expression in human endometrial adenocarcinoma xenografts
    • Y. Gong, L.C. Murphy, and L.J. Murphy Hormonal regulation of proliferation and transforming growth factors gene expression in human endometrial adenocarcinoma xenografts J. Steroid. Biochem. Mol. Biol. 50 1994 13 19
    • (1994) J. Steroid. Biochem. Mol. Biol. , vol.50 , pp. 13-19
    • Gong, Y.1    Murphy, L.C.2    Murphy, L.J.3
  • 21
    • 0027201501 scopus 로고
    • Two-year carcinogenicity study of tamoxifen in alderley park wistar-derived rats
    • P. Greaves, R. Goonetilleke, G. Nunn, J. Topham, and T. Orton Two-year carcinogenicity study of tamoxifen in alderley park wistar-derived rats Cancer Res. 53 1993 3919 3924
    • (1993) Cancer Res. , vol.53 , pp. 3919-3924
    • Greaves, P.1    Goonetilleke, R.2    Nunn, G.3    Topham, J.4    Orton, T.5
  • 22
    • 0026606580 scopus 로고
    • Induction of covalent DNA adducts in rodents by tamoxifen
    • X.L. Han, and J.G. Liehr Induction of covalent DNA adducts in rodents by tamoxifen Cancer Res. 52 1992 1360 1363
    • (1992) Cancer Res. , vol.52 , pp. 1360-1363
    • Han, X.L.1    Liehr, J.G.2
  • 23
    • 0031302443 scopus 로고    scopus 로고
    • Tamoxifen exerts oestrogen-agonistic effects on proliferation and plasminogen activation, but not on gelatinase activity, glycogen metabolism and p53 protein expression, in cultures of oestrogen-responsive human endometrial adenocarcinoma cells
    • D. Hochner-Celnikier, C. Greenfield, Z. Finci-Yeheskel, A. Milwidsky, A. Gutman, D. Goldman-Wohl, S. Yagel, and M. Mayer Tamoxifen exerts oestrogen-agonistic effects on proliferation and plasminogen activation, but not on gelatinase activity, glycogen metabolism and p53 protein expression, in cultures of oestrogen-responsive human endometrial adenocarcinoma cells Mol. Hum. Reprod. 3 1997 1019 1027
    • (1997) Mol. Hum. Reprod. , vol.3 , pp. 1019-1027
    • Hochner-Celnikier, D.1    Greenfield, C.2    Finci-Yeheskel, Z.3    Milwidsky, A.4    Gutman, A.5    Goldman-Wohl, D.6    Yagel, S.7    Mayer, M.8
  • 24
    • 0031672555 scopus 로고    scopus 로고
    • Effect of tamoxifen on cholesterol synthesis in HepG2 cells and cultured rat hepatocytes
    • A.L. Holleran, B. Lindenthal, T.A. Aldaghlas, and J.K. Kelleher Effect of tamoxifen on cholesterol synthesis in HepG2 cells and cultured rat hepatocytes Metabolism 47 1998 1504 1513
    • (1998) Metabolism , vol.47 , pp. 1504-1513
    • Holleran, A.L.1    Lindenthal, B.2    Aldaghlas, T.A.3    Kelleher, J.K.4
  • 25
    • 0029878240 scopus 로고    scopus 로고
    • The effects of tamoxifen on the uterus
    • S.M. Ismail The effects of tamoxifen on the uterus Curr. Opin. Obstet. Gynecol. 8 1996 27 31
    • (1996) Curr. Opin. Obstet. Gynecol. , vol.8 , pp. 27-31
    • Ismail, S.M.1
  • 26
    • 0030031782 scopus 로고    scopus 로고
    • Estrogen receptors: Bioactivities and interactions with cell signaling pathways
    • B.S. Katzenellenbogen Estrogen receptors: bioactivities and interactions with cell signaling pathways Biol. Reprod. 54 1996 287 293
    • (1996) Biol. Reprod. , vol.54 , pp. 287-293
    • Katzenellenbogen, B.S.1
  • 27
    • 0028287647 scopus 로고
    • Effects of tamoxifen on uterus and ovaries of postmenopausal women in a randomised breast cancer prevention trial
    • R.P. Kedar, T.H. Bourne, T.J. Powles, W.P. Collins, S.E. Ashley, D.O. Cosgrove, and S. Campbell Effects of tamoxifen on uterus and ovaries of postmenopausal women in a randomised breast cancer prevention trial Lancet 343 1994 1318 1321
    • (1994) Lancet , vol.343 , pp. 1318-1321
    • Kedar, R.P.1    Bourne, T.H.2    Powles, T.J.3    Collins, W.P.4    Ashley, S.E.5    Cosgrove, D.O.6    Campbell, S.7
  • 30
    • 0030061949 scopus 로고    scopus 로고
    • C-Myc overexpression associated DHFR gene amplification in hamster, rat, mouse and human cell lines
    • S. Mai, J. Hanley-Hyde, and M. Fluri c-Myc overexpression associated DHFR gene amplification in hamster, rat, mouse and human cell lines Oncogene 12 1996 277 288
    • (1996) Oncogene , vol.12 , pp. 277-288
    • Mai, S.1    Hanley-Hyde, J.2    Fluri, M.3
  • 31
    • 0035181465 scopus 로고    scopus 로고
    • Mechanisms of tamoxifen-induced apoptosis
    • S. Mandlekar, and A.N. Kong Mechanisms of tamoxifen-induced apoptosis Apoptosis 6 2001 469 477
    • (2001) Apoptosis , vol.6 , pp. 469-477
    • Mandlekar, S.1    Kong, A.N.2
  • 34
    • 0036234436 scopus 로고    scopus 로고
    • Apoptosis and apoptosis-associated parameters in relation to tamoxifen exposure in postmenopausal endometrium
    • M.J. Mourits, H. Hollema, E.G. De Vries, K.A. Ten Hoor, P.H. Willemse, and A.G. Van Der Zee Apoptosis and apoptosis-associated parameters in relation to tamoxifen exposure in postmenopausal endometrium Hum. Pathol. 33 2002 341 346
    • (2002) Hum. Pathol. , vol.33 , pp. 341-346
    • Mourits, M.J.1    Hollema, H.2    De Vries, E.G.3    Ten Hoor, K.A.4    Willemse, P.H.5    Van Der Zee, A.G.6
  • 36
  • 37
    • 0033964226 scopus 로고    scopus 로고
    • Guidelines for monitoring patients taking tamoxifen treatment
    • P. Neven, and H. Vernaeve Guidelines for monitoring patients taking tamoxifen treatment Drug Saf. 22 2000 1 11
    • (2000) Drug Saf. , vol.22 , pp. 1-11
    • Neven, P.1    Vernaeve, H.2
  • 38
    • 0033856957 scopus 로고    scopus 로고
    • Investigation of the Alamar Blue (resazurin) fluorescent dye for the assessment of mammalian cell cytotoxicity
    • J. O'Brien, I. Wilson, T. Orton, and F. Pognan Investigation of the Alamar Blue (resazurin) fluorescent dye for the assessment of mammalian cell cytotoxicity Eur. J. Biochem. 267 2000 5421 5426
    • (2000) Eur. J. Biochem. , vol.267 , pp. 5421-5426
    • O'Brien, J.1    Wilson, I.2    Orton, T.3    Pognan, F.4
  • 41
    • 0034989609 scopus 로고    scopus 로고
    • Understanding the genotoxicity of tamoxifen?
    • D.H. Phillips Understanding the genotoxicity of tamoxifen? Carcinogenesis 22 2001 839 849
    • (2001) Carcinogenesis , vol.22 , pp. 839-849
    • Phillips, D.H.1
  • 42
    • 0029985407 scopus 로고    scopus 로고
    • Activation of tamoxifen and its metabolite alpha-hydroxytamoxifen to DNA-binding products: Comparisons between human, rat and mouse hepatocytes
    • D.H. Phillips, P.L. Carmichael, A. Hewer, K.J. Cole, I.R. Hardcastle, G.K. Poon, A. Keogh, and A.J. Strain Activation of tamoxifen and its metabolite alpha-hydroxytamoxifen to DNA-binding products: comparisons between human, rat and mouse hepatocytes Carcinogenesis 17 1996 89 94
    • (1996) Carcinogenesis , vol.17 , pp. 89-94
    • Phillips, D.H.1    Carmichael, P.L.2    Hewer, A.3    Cole, K.J.4    Hardcastle, I.R.5    Poon, G.K.6    Keogh, A.7    Strain, A.J.8
  • 43
    • 0028179723 scopus 로고
    • Co-chromatography of a tamoxifen epoxide-deoxyguanylic acid adduct with a major DNA adduct formed in the livers of tamoxifen-treated rats
    • D.H. Phillips, A. Hewer, I.N. White, and P.B. Farmer Co-chromatography of a tamoxifen epoxide-deoxyguanylic acid adduct with a major DNA adduct formed in the livers of tamoxifen-treated rats Carcinogenesis 15 1994 793 795
    • (1994) Carcinogenesis , vol.15 , pp. 793-795
    • Phillips, D.H.1    Hewer, A.2    White, I.N.3    Farmer, P.B.4
  • 44
    • 0037480762 scopus 로고    scopus 로고
    • The genotoxicity of tamoxifen: Extent and consequences, kona, hawaii, January 23, 2003
    • M.C. Poirier, and L.J. Schild The genotoxicity of tamoxifen: extent and consequences, kona, hawaii, January 23, 2003 Mutagenesis 18 2003 395 399
    • (2003) Mutagenesis , vol.18 , pp. 395-399
    • Poirier, M.C.1    Schild, L.J.2
  • 45
    • 0031056093 scopus 로고    scopus 로고
    • Efficacy of tamoxifen as treatment of breast cancer
    • T.J. Powles Efficacy of tamoxifen as treatment of breast cancer Semin. Oncol. 24 1997 S1-48 S41-54
    • (1997) Semin. Oncol. , vol.24
    • Powles, T.J.1
  • 46
    • 0037051672 scopus 로고    scopus 로고
    • Effect of prolonged hydroxytamoxifen treatment of MCF-7 cells on mitogen activated kinase cascade
    • F. Rabenoelina, A. Semlali, M.J. Duchesne, G. Freiss, M. Pons, and E. Badia Effect of prolonged hydroxytamoxifen treatment of MCF-7 cells on mitogen activated kinase cascade Int. J. Cancer 98 2002 698 706
    • (2002) Int. J. Cancer , vol.98 , pp. 698-706
    • Rabenoelina, F.1    Semlali, A.2    Duchesne, M.J.3    Freiss, G.4    Pons, M.5    Badia, E.6
  • 47
    • 0031114483 scopus 로고    scopus 로고
    • GeneCards: Integrating information about genes, proteins and diseases
    • M. Rebhan, V. Chalifa-Caspi, J. Prilusky, and D. Lancet GeneCards: integrating information about genes, proteins and diseases Trends Genet. 13 1997 163
    • (1997) Trends Genet. , vol.13 , pp. 163
    • Rebhan, M.1    Chalifa-Caspi, V.2    Prilusky, J.3    Lancet, D.4
  • 48
    • 0032412151 scopus 로고    scopus 로고
    • Evidence that tamoxifen preserves bone density in late postmenopausal women with breast cancer
    • A. Resch, E. Biber, M. Seifert, and H. Resch Evidence that tamoxifen preserves bone density in late postmenopausal women with breast cancer Acta Oncol. 37 1998 661 664
    • (1998) Acta Oncol. , vol.37 , pp. 661-664
    • Resch, A.1    Biber, E.2    Seifert, M.3    Resch, H.4
  • 49
    • 0029922973 scopus 로고    scopus 로고
    • Cultured endometrial cancer cells exhibit autocrine growth factor stimulation that is not observed in cultured normal endometrial cells
    • R.K. Reynolds, C.A. Owens, and J.A. Roberts Cultured endometrial cancer cells exhibit autocrine growth factor stimulation that is not observed in cultured normal endometrial cells Gynecol. Oncol. 60 1996 380 386
    • (1996) Gynecol. Oncol. , vol.60 , pp. 380-386
    • Reynolds, R.K.1    Owens, C.A.2    Roberts, J.A.3
  • 51
    • 0028412266 scopus 로고
    • Ovarian hormones and the cardiovascular system: Recent findings
    • G.M. Rosano, and P.M. Sarrel Ovarian hormones and the cardiovascular system: recent findings Cardiologia 39 1994 275 279
    • (1994) Cardiologia , vol.39 , pp. 275-279
    • Rosano, G.M.1    Sarrel, P.M.2
  • 52
    • 0028898873 scopus 로고
    • Adjuvant tamoxifen therapy for early stage breast cancer and second primary malignancies
    • Stockholm Breast Cancer Study Group N.
    • L.E. Rutqvist, H. Johansson, T. Signomklao, U. Johansson, T. Fornander, N. Wilking Stockholm Breast Cancer Study Group Adjuvant tamoxifen therapy for early stage breast cancer and second primary malignancies J. Natl. Cancer Inst. 87 1995 645 651
    • (1995) J. Natl. Cancer Inst. , vol.87 , pp. 645-651
    • Rutqvist, L.E.1    Johansson, H.2    Signomklao, T.3    Johansson, U.4    Fornander, T.5    Wilking6
  • 53
    • 0035824666 scopus 로고    scopus 로고
    • A novel transrepression pathway of c-Myc. Recruitment of a transcriptional corepressor complex to c-Myc by MM-1, ac-Myc-binding protein
    • A. Satou, T. Taira, S.M. Iguchi-Ariga, and H. Ariga A novel transrepression pathway of c-Myc. Recruitment of a transcriptional corepressor complex to c-Myc by MM-1, ac-Myc-binding protein J. Biol. Chem. 276 2001 46562 46567
    • (2001) J. Biol. Chem. , vol.276 , pp. 46562-46567
    • Satou, A.1    Taira, T.2    Iguchi-Ariga, S.M.3    Ariga, H.4
  • 54
    • 0035878865 scopus 로고    scopus 로고
    • Identification of differentially expressed genes in hepatocellular carcinoma and metastatic liver tumors by oligonucleotide expression profiling
    • D. Tackels-Horne, M.D. Goodman, A.J. Williams, D.J. Wilson, T. Eskandari, L.M. Vogt, J.F. Boland, U. Scherf, and J.G. Vockley Identification of differentially expressed genes in hepatocellular carcinoma and metastatic liver tumors by oligonucleotide expression profiling Cancer 92 2001 395 405
    • (2001) Cancer , vol.92 , pp. 395-405
    • Tackels-Horne, D.1    Goodman, M.D.2    Williams, A.J.3    Wilson, D.J.4    Eskandari, T.5    Vogt, L.M.6    Boland, J.F.7    Scherf, U.8    Vockley, J.G.9
  • 55
    • 0035992104 scopus 로고    scopus 로고
    • Serum placental protein 14: A novel marker of selective oestrogen receptor modulator action on the postmenopausal endometrium
    • L.B. Tanko, L. Warming, Y.Z. Bagger, I. Byrjalsen, S. Jensen, and C. Christiansen Serum placental protein 14: a novel marker of selective oestrogen receptor modulator action on the postmenopausal endometrium Biomarkers 7 2002 257 266
    • (2002) Biomarkers , vol.7 , pp. 257-266
    • Tanko, L.B.1    Warming, L.2    Bagger, Y.Z.3    Byrjalsen, I.4    Jensen, S.5    Christiansen, C.6
  • 56
    • 0031042709 scopus 로고    scopus 로고
    • Comparative metabolism of tamoxifen and DNA adduct formation and in vitro studies on genotoxicity
    • S.R. Tannenbaum Comparative metabolism of tamoxifen and DNA adduct formation and in vitro studies on genotoxicity Semin. Oncol. 24 1997 S18-1 S81-86
    • (1997) Semin. Oncol. , vol.24
    • Tannenbaum, S.R.1
  • 60
    • 0028901194 scopus 로고
    • Tamoxifen activation of the estrogen receptor/AP-1 pathway: Potential origin for the cell-specific estrogen-like effects of antiestrogens
    • P. Webb, G.N. Lopez, R.M. Uht, and P.J. Kushner Tamoxifen activation of the estrogen receptor/AP-1 pathway: potential origin for the cell-specific estrogen-like effects of antiestrogens Mol. Endocrinol. 9 1995 443 456
    • (1995) Mol. Endocrinol. , vol.9 , pp. 443-456
    • Webb, P.1    Lopez, G.N.2    Uht, R.M.3    Kushner, P.J.4
  • 62
    • 0032808213 scopus 로고    scopus 로고
    • The tamoxifen dilemma
    • I.N. White The tamoxifen dilemma Carcinogenesis 20 1999 1153 1160
    • (1999) Carcinogenesis , vol.20 , pp. 1153-1160
    • White, I.N.1
  • 63
    • 0035977884 scopus 로고    scopus 로고
    • Anti-oestrogenic drugs and endometrial cancers
    • I.N. White Anti-oestrogenic drugs and endometrial cancers Toxicol. Lett. 120 2001 21 29
    • (2001) Toxicol. Lett. , vol.120 , pp. 21-29
    • White, I.N.1
  • 64
    • 0027054733 scopus 로고
    • Genotoxic potential of tamoxifen and analogues in female Fischer F344/n rats, DBA/2 and C57BL/6 mice and in human MCL-5 cells
    • I.N. White, F. de Matteis, A. Davies, L.L. Smith, C. Crofton-Sleigh, S. Venitt, A. Hewer, and D.H. Phillips Genotoxic potential of tamoxifen and analogues in female Fischer F344/n rats, DBA/2 and C57BL/6 mice and in human MCL-5 cells Carcinogenesis 13 1992 2197 2203
    • (1992) Carcinogenesis , vol.13 , pp. 2197-2203
    • White, I.N.1    De Matteis, F.2    Davies, A.3    Smith, L.L.4    Crofton-Sleigh, C.5    Venitt, S.6    Hewer, A.7    Phillips, D.H.8
  • 66
    • 0034614615 scopus 로고    scopus 로고
    • Activation of the p38 mitogen-activated protein kinase pathway by estrogen or by 4-hydroxytamoxifen is coupled to estrogen receptor-induced apoptosis
    • C.C. Zhang, and D.J. Shapiro Activation of the p38 mitogen-activated protein kinase pathway by estrogen or by 4-hydroxytamoxifen is coupled to estrogen receptor-induced apoptosis J. Biol. Chem. 275 2000 479 486
    • (2000) J. Biol. Chem. , vol.275 , pp. 479-486
    • Zhang, C.C.1    Shapiro, D.J.2


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