Activation of tamoxifen and its metabolite α-hydroxytamoxifen to DNA-binding products: Comparisons between human, rat and mouse hepatocytes

Carcinogenesis

Volumn 17, Issue 1, 1996, Pages 89-94

  Phillips, David H ^a   Carmichael, Paul L ^a   Hewer, Alan ^a   Cole, Kathleen J ^a   Hardcastle, Ian R ^a   Poon, Grace K ^a   Keogh, Adrian ^b   Strain, Alastair J ^b  

^a INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^b QUEEN ELIZABETH HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROXYTAMOXIFEN; TAMOXIFEN;

ADOLESCENT; ADULT; ANIMAL CELL; ARTICLE; CELL CULTURE; COMPARATIVE STUDY; CONTROLLED STUDY; CULTURE MEDIUM; DNA ADDUCT; DRUG ACTIVATION; DRUG DNA BINDING; FEMALE; HUMAN; HUMAN CELL; LIVER CELL; MALE; MASS SPECTROMETRY; METABOLIC ACTIVATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT; SCHOOL CHILD;

ADOLESCENT; ADULT; ANIMALS; BIOTRANSFORMATION; CHILD; DNA ADDUCTS; ESTROGEN ANTAGONISTS; FEMALE; HUMANS; LIVER; MALE; MICE; MIDDLE AGED; RATS; RATS, INBRED F344; SPECIES SPECIFICITY; TAMOXIFEN;

EID: 0029985407     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/17.1.89     Document Type: Article

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