메뉴 건너뛰기




Volumn 56, Issue 7, 1996, Pages 1475-1479

Lack of genotoxicity of tamoxifen in human endometrium

Author keywords

[No Author keywords available]

Indexed keywords

BENZO[A]PYRENE; DIMETHYL SULFOXIDE; HYDROXYTAMOXIFEN; TAMOXIFEN;

EID: 0029978834     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (150)

References (22)
  • 1
    • 0026557343 scopus 로고
    • Systemic treatment of early breast cancer by hormonal, cytotoxic, or immune therapy, 133 randomised trials involving 31,000 recurrences and 24,000 deaths among 75,000 women
    • Early Breast Cancer Trialists' Collaborative Group. Systemic treatment of early breast cancer by hormonal, cytotoxic, or immune therapy, 133 randomised trials involving 31,000 recurrences and 24,000 deaths among 75,000 women. Lancet, 339 1-15,71-85, 1992
    • (1992) Lancet , vol.339 , pp. 1-15
  • 2
    • 0027247929 scopus 로고
    • Tamoxifen how boldly to go where no women have gone before
    • Gray, R. Tamoxifen how boldly to go where no women have gone before. J Natl. Cancer Inst , 85 1358-1360, 1993.
    • (1993) J Natl. Cancer Inst , vol.85 , pp. 1358-1360
    • Gray, R.1
  • 3
    • 0027201501 scopus 로고
    • Two-year carcinogenicity study of tamoxifen in Alderley Park Wistar-derived rats
    • Greaves, P., Goonetilleke, R., Nunn, G., Topham, J., and Orton, T Two-year carcinogenicity study of tamoxifen in Alderley Park Wistar-derived rats Cancer Res., 53: 3919-3924, 1993
    • (1993) Cancer Res. , vol.53 , pp. 3919-3924
    • Greaves, P.1    Goonetilleke, R.2    Nunn, G.3    Topham, J.4    Orton, T.5
  • 4
    • 0026606580 scopus 로고
    • Induction of covalent DNA adducts in rodents by tamoxifen
    • Han, X., and Liehr, J. G. Induction of covalent DNA adducts in rodents by tamoxifen. Cancer Res , 52. 1360-1363, 1992
    • (1992) Cancer Res , vol.52 , pp. 1360-1363
    • Han, X.1    Liehr, J.G.2
  • 5
    • 0027054733 scopus 로고
    • Genotoxic potential of tamoxifen and analogues in female Fischer F344/n rats, DBA/2and C57B1/6 mice and in human MCL-5 cells
    • Lond.
    • White, I N H , de Mateis, F., Davies, A., Smith, L. L., Crofton-Sleigh, C , Venitt, S., Hewer, A., and Phillips, D. H. Genotoxic potential of tamoxifen and analogues in female Fischer F344/n rats, DBA/2and C57B1/6 mice and in human MCL-5 cells. Carcinogenesis (Lond.), 13: 2197-2203, 1992
    • (1992) Carcinogenesis , vol.13 , pp. 2197-2203
    • White, I.N.H.1    De Mateis, F.2    Davies, A.3    Smith, L.L.4    Crofton-Sleigh, C.5    Venitt, S.6    Hewer, A.7    Phillips, D.H.8
  • 6
    • 0027217202 scopus 로고
    • Micronucleus assays using cytochalasin-blocked MCL-5 cells, a proprietary human cell line expressing five human cytochromes P-450 and microsomal epoxide hydrolase
    • Crofton-Sleigh, C , Doherty, A., Ellard, S , Parry, E. M., and Venitt, S. Micronucleus assays using cytochalasin-blocked MCL-5 cells, a proprietary human cell line expressing five human cytochromes P-450 and microsomal epoxide hydrolase. Mutagenesis, 8: 363-372, 1993.
    • (1993) Mutagenesis , vol.8 , pp. 363-372
    • Crofton-Sleigh, C.1    Doherty, A.2    Ellard, S.3    Parry, E.M.4    Venitt, S.5
  • 7
    • 0026096161 scopus 로고
    • A metabolically competent human cell line expressing five cDNAs encoding procarcinogen-activating enzymes: Application to mutagenicity testing
    • Crespi, C. L , Gonzales, F. J , Steimel, D. T , Turner, T. R., Gelboin, H. V., Periman, B W., and Langenbach, R. A metabolically competent human cell line expressing five cDNAs encoding procarcinogen-activating enzymes: application to mutagenicity testing. Chem. Res. Toxicol., 4: 566-572, 1991.
    • (1991) Chem. Res. Toxicol. , vol.4 , pp. 566-572
    • Crespi, C.L.1    Gonzales, F.J.2    Steimel, D.T.3    Turner, T.R.4    Gelboin, H.V.5    Periman, B.W.6    Langenbach, R.7
  • 8
    • 0026319776 scopus 로고
    • Cytochrome P-450-mediated activation and irreversible binding of the antiestrogen tamoxifen to proteins in rat and human liver: Possible involvement of flavin-containing monooxygenases in tamoxifen activation
    • Mani, C , and Kupfer, D. Cytochrome P-450-mediated activation and irreversible binding of the antiestrogen tamoxifen to proteins in rat and human liver: possible involvement of flavin-containing monooxygenases in tamoxifen activation. Cancer Res., 51: 6052-6058, 1991.
    • (1991) Cancer Res. , vol.51 , pp. 6052-6058
    • Mani, C.1    Kupfer, D.2
  • 9
    • 0028210878 scopus 로고
    • DNA adduct formation by tamoxifen with rat and human liver microsomal activation systems
    • Lond
    • Pathak, D. N., and Bodell, W. J. DNA adduct formation by tamoxifen with rat and human liver microsomal activation systems. Carcinogenesis (Lond ), 15: 529-532, 1994.
    • (1994) Carcinogenesis , vol.15 , pp. 529-532
    • Pathak, D.N.1    Bodell, W.J.2
  • 10
    • 0028233205 scopus 로고
    • Tamoxifen induces hepatic aneuploidy and mitotic spindle disruption after a single in vivo administration to female Sprague-Dawley rats
    • Sargent, L. M , Dragan, V. P., Bahnub, H., Wiley, J E., Sattler, C. A., Schroeder, P , Sattler, G. L., Jordan, V. C., and Pitot, H. C. Tamoxifen induces hepatic aneuploidy and mitotic spindle disruption after a single in vivo administration to female Sprague-Dawley rats. Cancer Res , 54: 3357-3360, 1994.
    • (1994) Cancer Res , vol.54 , pp. 3357-3360
    • Sargent, L.M.1    Dragan, V.P.2    Bahnub, H.3    Wiley, J.E.4    Sattler, C.A.5    Schroeder, P.6    Sattler, G.L.7    Jordan, V.C.8    Pitot, H.C.9
  • 11
    • 0027930072 scopus 로고
    • Frequent and specific mutations of the rat p53 gene in hepatocarcinomas induced by tamoxifen
    • Vancutsem, P. L., Lazarus, P., and Williams, G. M. Frequent and specific mutations of the rat p53 gene in hepatocarcinomas induced by tamoxifen Cancer Res., 54: 3864-3867, 1994.
    • (1994) Cancer Res. , vol.54 , pp. 3864-3867
    • Vancutsem, P.L.1    Lazarus, P.2    Williams, G.M.3
  • 12
    • 0028208456 scopus 로고
    • Endometrial cancer in tamoxifen-treated breast cancer patients: Findings from the National Surgical Adjuvant Breast and Bowel Project (NSABP) B-14
    • Fisher, B., Costantino, J. P., Redmond, C K., Fisher, E. R., Wickerham, D. L., and Cronin, W. W. Endometrial cancer in tamoxifen-treated breast cancer patients: findings from the National Surgical Adjuvant Breast and Bowel Project (NSABP) B-14. J. Natl. Cancer Inst., 86: 527-537, 1994.
    • (1994) J. Natl. Cancer Inst. , vol.86 , pp. 527-537
    • Fisher, B.1    Costantino, J.P.2    Redmond, C.K.3    Fisher, E.R.4    Wickerham, D.L.5    Cronin, W.W.6
  • 14
    • 0029012731 scopus 로고
    • Tamoxifen and the induction of cancer
    • Lond
    • King, C M. Tamoxifen and the induction of cancer. Carcinogenesis (Lond ), 16: 11449-11454, 1995.
    • (1995) Carcinogenesis , vol.16 , pp. 11449-11454
    • King, C.M.1
  • 15
    • 0028172242 scopus 로고
    • α-Hydroxytamoxifen, a metabolite of tamoxifen with exceptionally high DNA-binding activity in rat hepatocytes
    • Phillips, D. H., Carmichael, P. L , Hewer, A., Cole, K J., and Poon, G. K α-Hydroxytamoxifen, a metabolite of tamoxifen with exceptionally high DNA-binding activity in rat hepatocytes. Cancer Res., 54: 5518-5522, 1994.
    • (1994) Cancer Res. , vol.54 , pp. 5518-5522
    • Phillips, D.H.1    Carmichael, P.L.2    Hewer, A.3    Cole, K.J.4    Poon, G.K.5
  • 17
    • 0023804129 scopus 로고
    • Formation of DNA adducts in human skin maintained in short-term organ culture and treated with coal-tar, creosote or bitumen
    • Schoket, B., Hewer, A., Grover, P. L., and Phillips, D. H. Formation of DNA adducts in human skin maintained in short-term organ culture and treated with coal-tar, creosote or bitumen. Int. J. Cancer, 42. 622-626, 1988
    • (1988) Int. J. Cancer , vol.42 , pp. 622-626
    • Schoket, B.1    Hewer, A.2    Grover, P.L.3    Phillips, D.H.4
  • 18
    • 0000530035 scopus 로고
    • Non-random binding of the carcinogen N-hydroxy-2-acetylaminofluorene to repetitive sequences of rat liver DNA in vivo
    • Gupta, R. C. Non-random binding of the carcinogen N-hydroxy-2-acetylaminofluorene to repetitive sequences of rat liver DNA in vivo. Proc Natl. Acad. Sci USA, 81: 6943-6947, 1984.
    • (1984) Proc Natl. Acad. Sci USA , vol.81 , pp. 6943-6947
    • Gupta, R.C.1
  • 19
    • 0028179723 scopus 로고
    • Co-chromatography of a tamoxifen epoxide-deoxyguanylic acid adduct with a major DNA adduct formed in the livers of tamoxifen-treated rats
    • Lond.
    • Phillips, D. H , Hewer, A., White, I. N. H , and Farmer, P B Co-chromatography of a tamoxifen epoxide-deoxyguanylic acid adduct with a major DNA adduct formed in the livers of tamoxifen-treated rats Carcinogenesis (Lond.), 15: 793-795, 1994.
    • (1994) Carcinogenesis , vol.15 , pp. 793-795
    • Phillips, D.H.1    Hewer, A.2    White, I.N.H.3    Farmer, P.B.4
  • 21
    • 0029985407 scopus 로고    scopus 로고
    • Activation of tamoxifen and its metabolite α-hydroxytamoxifen to DNA-binding products: Comparisons between human, rat and mouse hepatocytes
    • Lond.
    • Phillips, D. H., Carmichael, P. L., Hewer, A., Cole, K. J., Hardcastle, I. R , Poon, G K., Keogh, A., and Strain, A. J. Activation of tamoxifen and its metabolite α-hydroxytamoxifen to DNA-binding products: comparisons between human, rat and mouse hepatocytes. Carcinogenesis (Lond.), 17: 89-94, 1996.
    • (1996) Carcinogenesis , vol.17 , pp. 89-94
    • Phillips, D.H.1    Carmichael, P.L.2    Hewer, A.3    Cole, K.J.4    Hardcastle, I.R.5    Poon, G.K.6    Keogh, A.7    Strain, A.J.8
  • 22
    • 0030050137 scopus 로고    scopus 로고
    • Identification of the major tamoxifen-deoxyguanosine adduct formed in the liver DNA of rats treated with tamoxifen
    • Osborne, M R , Hewer, A., Hardcastle, I. R., Carmichael, P L , and Phillips, D. H Identification of the major tamoxifen-deoxyguanosine adduct formed in the liver DNA of rats treated with tamoxifen. Cancer Res., 56. 66-71, 1996.
    • (1996) Cancer Res. , vol.56 , pp. 66-71
    • Osborne, M.R.1    Hewer, A.2    Hardcastle, I.R.3    Carmichael, P.L.4    Phillips, D.H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.