-
1
-
-
0026557343
-
Systemic treatment of early breast cancer by hormonal, cytotoxic, or immune therapy, 133 randomised trials involving 31,000 recurrences and 24,000 deaths among 75,000 women
-
Early Breast Cancer Trialists' Collaborative Group. Systemic treatment of early breast cancer by hormonal, cytotoxic, or immune therapy, 133 randomised trials involving 31,000 recurrences and 24,000 deaths among 75,000 women. Lancet, 339 1-15,71-85, 1992
-
(1992)
Lancet
, vol.339
, pp. 1-15
-
-
-
2
-
-
0027247929
-
Tamoxifen how boldly to go where no women have gone before
-
Gray, R. Tamoxifen how boldly to go where no women have gone before. J Natl. Cancer Inst , 85 1358-1360, 1993.
-
(1993)
J Natl. Cancer Inst
, vol.85
, pp. 1358-1360
-
-
Gray, R.1
-
3
-
-
0027201501
-
Two-year carcinogenicity study of tamoxifen in Alderley Park Wistar-derived rats
-
Greaves, P., Goonetilleke, R., Nunn, G., Topham, J., and Orton, T Two-year carcinogenicity study of tamoxifen in Alderley Park Wistar-derived rats Cancer Res., 53: 3919-3924, 1993
-
(1993)
Cancer Res.
, vol.53
, pp. 3919-3924
-
-
Greaves, P.1
Goonetilleke, R.2
Nunn, G.3
Topham, J.4
Orton, T.5
-
4
-
-
0026606580
-
Induction of covalent DNA adducts in rodents by tamoxifen
-
Han, X., and Liehr, J. G. Induction of covalent DNA adducts in rodents by tamoxifen. Cancer Res , 52. 1360-1363, 1992
-
(1992)
Cancer Res
, vol.52
, pp. 1360-1363
-
-
Han, X.1
Liehr, J.G.2
-
5
-
-
0027054733
-
Genotoxic potential of tamoxifen and analogues in female Fischer F344/n rats, DBA/2and C57B1/6 mice and in human MCL-5 cells
-
Lond.
-
White, I N H , de Mateis, F., Davies, A., Smith, L. L., Crofton-Sleigh, C , Venitt, S., Hewer, A., and Phillips, D. H. Genotoxic potential of tamoxifen and analogues in female Fischer F344/n rats, DBA/2and C57B1/6 mice and in human MCL-5 cells. Carcinogenesis (Lond.), 13: 2197-2203, 1992
-
(1992)
Carcinogenesis
, vol.13
, pp. 2197-2203
-
-
White, I.N.H.1
De Mateis, F.2
Davies, A.3
Smith, L.L.4
Crofton-Sleigh, C.5
Venitt, S.6
Hewer, A.7
Phillips, D.H.8
-
6
-
-
0027217202
-
Micronucleus assays using cytochalasin-blocked MCL-5 cells, a proprietary human cell line expressing five human cytochromes P-450 and microsomal epoxide hydrolase
-
Crofton-Sleigh, C , Doherty, A., Ellard, S , Parry, E. M., and Venitt, S. Micronucleus assays using cytochalasin-blocked MCL-5 cells, a proprietary human cell line expressing five human cytochromes P-450 and microsomal epoxide hydrolase. Mutagenesis, 8: 363-372, 1993.
-
(1993)
Mutagenesis
, vol.8
, pp. 363-372
-
-
Crofton-Sleigh, C.1
Doherty, A.2
Ellard, S.3
Parry, E.M.4
Venitt, S.5
-
7
-
-
0026096161
-
A metabolically competent human cell line expressing five cDNAs encoding procarcinogen-activating enzymes: Application to mutagenicity testing
-
Crespi, C. L , Gonzales, F. J , Steimel, D. T , Turner, T. R., Gelboin, H. V., Periman, B W., and Langenbach, R. A metabolically competent human cell line expressing five cDNAs encoding procarcinogen-activating enzymes: application to mutagenicity testing. Chem. Res. Toxicol., 4: 566-572, 1991.
-
(1991)
Chem. Res. Toxicol.
, vol.4
, pp. 566-572
-
-
Crespi, C.L.1
Gonzales, F.J.2
Steimel, D.T.3
Turner, T.R.4
Gelboin, H.V.5
Periman, B.W.6
Langenbach, R.7
-
8
-
-
0026319776
-
Cytochrome P-450-mediated activation and irreversible binding of the antiestrogen tamoxifen to proteins in rat and human liver: Possible involvement of flavin-containing monooxygenases in tamoxifen activation
-
Mani, C , and Kupfer, D. Cytochrome P-450-mediated activation and irreversible binding of the antiestrogen tamoxifen to proteins in rat and human liver: possible involvement of flavin-containing monooxygenases in tamoxifen activation. Cancer Res., 51: 6052-6058, 1991.
-
(1991)
Cancer Res.
, vol.51
, pp. 6052-6058
-
-
Mani, C.1
Kupfer, D.2
-
9
-
-
0028210878
-
DNA adduct formation by tamoxifen with rat and human liver microsomal activation systems
-
Lond
-
Pathak, D. N., and Bodell, W. J. DNA adduct formation by tamoxifen with rat and human liver microsomal activation systems. Carcinogenesis (Lond ), 15: 529-532, 1994.
-
(1994)
Carcinogenesis
, vol.15
, pp. 529-532
-
-
Pathak, D.N.1
Bodell, W.J.2
-
10
-
-
0028233205
-
Tamoxifen induces hepatic aneuploidy and mitotic spindle disruption after a single in vivo administration to female Sprague-Dawley rats
-
Sargent, L. M , Dragan, V. P., Bahnub, H., Wiley, J E., Sattler, C. A., Schroeder, P , Sattler, G. L., Jordan, V. C., and Pitot, H. C. Tamoxifen induces hepatic aneuploidy and mitotic spindle disruption after a single in vivo administration to female Sprague-Dawley rats. Cancer Res , 54: 3357-3360, 1994.
-
(1994)
Cancer Res
, vol.54
, pp. 3357-3360
-
-
Sargent, L.M.1
Dragan, V.P.2
Bahnub, H.3
Wiley, J.E.4
Sattler, C.A.5
Schroeder, P.6
Sattler, G.L.7
Jordan, V.C.8
Pitot, H.C.9
-
11
-
-
0027930072
-
Frequent and specific mutations of the rat p53 gene in hepatocarcinomas induced by tamoxifen
-
Vancutsem, P. L., Lazarus, P., and Williams, G. M. Frequent and specific mutations of the rat p53 gene in hepatocarcinomas induced by tamoxifen Cancer Res., 54: 3864-3867, 1994.
-
(1994)
Cancer Res.
, vol.54
, pp. 3864-3867
-
-
Vancutsem, P.L.1
Lazarus, P.2
Williams, G.M.3
-
12
-
-
0028208456
-
Endometrial cancer in tamoxifen-treated breast cancer patients: Findings from the National Surgical Adjuvant Breast and Bowel Project (NSABP) B-14
-
Fisher, B., Costantino, J. P., Redmond, C K., Fisher, E. R., Wickerham, D. L., and Cronin, W. W. Endometrial cancer in tamoxifen-treated breast cancer patients: findings from the National Surgical Adjuvant Breast and Bowel Project (NSABP) B-14. J. Natl. Cancer Inst., 86: 527-537, 1994.
-
(1994)
J. Natl. Cancer Inst.
, vol.86
, pp. 527-537
-
-
Fisher, B.1
Costantino, J.P.2
Redmond, C.K.3
Fisher, E.R.4
Wickerham, D.L.5
Cronin, W.W.6
-
13
-
-
0028053224
-
Risk of endometrial cancer after tamoxifen treatment of breast cancer
-
van Leeuwen, F. E., Benraadt, J., Coebergh, J. W. W , Kiemeney, L. H. L. M., Gimbrere, C H. F , Otter, R , Schouten, I. J., Damhuis, R. A. M., Bortenbal, M., Diepenhorst, F. W., van den Belt-Dusebout, A. W., and van Tinteren, H. Risk of endometrial cancer after tamoxifen treatment of breast cancer. Lancet, 343: 448-452, 1994.
-
(1994)
Lancet
, vol.343
, pp. 448-452
-
-
Van Leeuwen, F.E.1
Benraadt, J.2
Coebergh, J.W.W.3
Kiemeney, L.H.L.M.4
Gimbrere, C.H.F.5
Otter, R.6
Schouten, I.J.7
Damhuis, R.A.M.8
Bortenbal, M.9
Diepenhorst, F.W.10
Van Den Belt-Dusebout, A.W.11
Van Tinteren, H.12
-
14
-
-
0029012731
-
Tamoxifen and the induction of cancer
-
Lond
-
King, C M. Tamoxifen and the induction of cancer. Carcinogenesis (Lond ), 16: 11449-11454, 1995.
-
(1995)
Carcinogenesis
, vol.16
, pp. 11449-11454
-
-
King, C.M.1
-
15
-
-
0028172242
-
α-Hydroxytamoxifen, a metabolite of tamoxifen with exceptionally high DNA-binding activity in rat hepatocytes
-
Phillips, D. H., Carmichael, P. L , Hewer, A., Cole, K J., and Poon, G. K α-Hydroxytamoxifen, a metabolite of tamoxifen with exceptionally high DNA-binding activity in rat hepatocytes. Cancer Res., 54: 5518-5522, 1994.
-
(1994)
Cancer Res.
, vol.54
, pp. 5518-5522
-
-
Phillips, D.H.1
Carmichael, P.L.2
Hewer, A.3
Cole, K.J.4
Poon, G.K.5
-
16
-
-
0022392658
-
Hydroxy derivatives of tamoxifen
-
Foster, A. B , Jarman, M., Leung, O-T., McCague, R., Leclercq, G., and Devleeschouwer, N. Hydroxy derivatives of tamoxifen. J. Med. Chem., 28. 1491-1497, 1985.
-
(1985)
J. Med. Chem.
, vol.28
, pp. 1491-1497
-
-
Foster, A.B.1
Jarman, M.2
Leung, O.-T.3
McCague, R.4
Leclercq, G.5
Devleeschouwer, N.6
-
17
-
-
0023804129
-
Formation of DNA adducts in human skin maintained in short-term organ culture and treated with coal-tar, creosote or bitumen
-
Schoket, B., Hewer, A., Grover, P. L., and Phillips, D. H. Formation of DNA adducts in human skin maintained in short-term organ culture and treated with coal-tar, creosote or bitumen. Int. J. Cancer, 42. 622-626, 1988
-
(1988)
Int. J. Cancer
, vol.42
, pp. 622-626
-
-
Schoket, B.1
Hewer, A.2
Grover, P.L.3
Phillips, D.H.4
-
18
-
-
0000530035
-
Non-random binding of the carcinogen N-hydroxy-2-acetylaminofluorene to repetitive sequences of rat liver DNA in vivo
-
Gupta, R. C. Non-random binding of the carcinogen N-hydroxy-2-acetylaminofluorene to repetitive sequences of rat liver DNA in vivo. Proc Natl. Acad. Sci USA, 81: 6943-6947, 1984.
-
(1984)
Proc Natl. Acad. Sci USA
, vol.81
, pp. 6943-6947
-
-
Gupta, R.C.1
-
19
-
-
0028179723
-
Co-chromatography of a tamoxifen epoxide-deoxyguanylic acid adduct with a major DNA adduct formed in the livers of tamoxifen-treated rats
-
Lond.
-
Phillips, D. H , Hewer, A., White, I. N. H , and Farmer, P B Co-chromatography of a tamoxifen epoxide-deoxyguanylic acid adduct with a major DNA adduct formed in the livers of tamoxifen-treated rats Carcinogenesis (Lond.), 15: 793-795, 1994.
-
(1994)
Carcinogenesis
, vol.15
, pp. 793-795
-
-
Phillips, D.H.1
Hewer, A.2
White, I.N.H.3
Farmer, P.B.4
-
20
-
-
0028168009
-
5-ethyl]-tamoxifen implicates α-hydroxylation of the ethyl group as a major pathway of tamoxifen activation to a liver carcinogen
-
Lond.
-
5-ethyl]-tamoxifen implicates α-hydroxylation of the ethyl group as a major pathway of tamoxifen activation to a liver carcinogen Carcinogenesis (Lond.) 15: 1487-1492, 1994.
-
(1994)
Carcinogenesis
, vol.15
, pp. 1487-1492
-
-
Phillips, D.H.1
Potter, G.A.2
Horton, M.N.3
Hewer, A.4
Crofton-Sleigh, C.5
Jarman, M.6
Venitt, S.7
-
21
-
-
0029985407
-
Activation of tamoxifen and its metabolite α-hydroxytamoxifen to DNA-binding products: Comparisons between human, rat and mouse hepatocytes
-
Lond.
-
Phillips, D. H., Carmichael, P. L., Hewer, A., Cole, K. J., Hardcastle, I. R , Poon, G K., Keogh, A., and Strain, A. J. Activation of tamoxifen and its metabolite α-hydroxytamoxifen to DNA-binding products: comparisons between human, rat and mouse hepatocytes. Carcinogenesis (Lond.), 17: 89-94, 1996.
-
(1996)
Carcinogenesis
, vol.17
, pp. 89-94
-
-
Phillips, D.H.1
Carmichael, P.L.2
Hewer, A.3
Cole, K.J.4
Hardcastle, I.R.5
Poon, G.K.6
Keogh, A.7
Strain, A.J.8
-
22
-
-
0030050137
-
Identification of the major tamoxifen-deoxyguanosine adduct formed in the liver DNA of rats treated with tamoxifen
-
Osborne, M R , Hewer, A., Hardcastle, I. R., Carmichael, P L , and Phillips, D. H Identification of the major tamoxifen-deoxyguanosine adduct formed in the liver DNA of rats treated with tamoxifen. Cancer Res., 56. 66-71, 1996.
-
(1996)
Cancer Res.
, vol.56
, pp. 66-71
-
-
Osborne, M.R.1
Hewer, A.2
Hardcastle, I.R.3
Carmichael, P.L.4
Phillips, D.H.5
|