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Volumn 45, Issue 2, 2004, Pages 237-245

Effect of imatinib mesylate on chronic myelogenous leukemia hematopoietic progenitor cells

Author keywords

BCR ABL; Chronic myelogenous leukaemia; Hematopoietic progenitors; Imatinib mesylate; Stem cells

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; 6 (2,6 DICHLOROPHENYL) 2 (4 FLUORO 3 METHYLANILINO) 8 METHYL 8H PYRIDO[2,3 D]PYRIMIDIN 7 ONE; ALPHA INTERFERON; ARSENIC TRIOXIDE; BCR ABL PROTEIN; CYTARABINE; DAUNORUBICIN; HOMOHARRINGTONINE; HYDROXYUREA; IMATINIB; LONAFARNIB; PROTEIN FARNESYLTRANSFERASE INHIBITOR; PROTEIN TYROSINE KINASE; PYRIDO[2,3 D]PYRIMIDINE DERIVATIVE; UNCLASSIFIED DRUG; WORTMANNIN;

EID: 0842322903     PISSN: 10428194     EISSN: None     Source Type: Journal    
DOI: 10.1080/1042819031000151905     Document Type: Review
Times cited : (20)

References (45)
  • 1
    • 0017653321 scopus 로고
    • "Chronic myelocytic leukemia: Clonal origin in a stem cell common to the granulocyte, erythrocyte, platelet and monocyte/macrophage"
    • Fialkow, P.J., Jacobson, R.J. and Papayannopoulou, T. (1977) "Chronic myelocytic leukemia: clonal origin in a stem cell common to the granulocyte, erythrocyte, platelet and monocyte/macrophage", American Journal of Medicine, 63, 125-130.
    • (1977) American Journal of Medicine , vol.63 , pp. 125-130
    • Fialkow, P.J.1    Jacobson, R.J.2    Papayannopoulou, T.3
  • 2
    • 0015694748 scopus 로고
    • "Letter: A new consistent chromosomal abnormality in chronic myelogenous leukaemia identified by quinacrine fluorescence and Giemsa staining"
    • Rowley, J.D. (1973) "Letter: A new consistent chromosomal abnormality in chronic myelogenous leukaemia identified by quinacrine fluorescence and Giemsa staining", Nature, 243, 290-293.
    • (1973) Nature , vol.243 , pp. 290-293
    • Rowley, J.D.1
  • 3
    • 0001044842 scopus 로고
    • "Transformation of an interleukin 3-dependent hematopoietic cell line by the chronic myelogenous leukemia-specific P210bcr/abl protein"
    • Daley, G.Q. and Baltimore, D. (1988) "Transformation of an interleukin 3-dependent hematopoietic cell line by the chronic myelogenous leukemia-specific P210bcr/abl protein", Proceedings of the National Academy of Sciences of the USA, 85, 9312-9316.
    • (1988) Proceedings of the National Academy of Sciences of the USA , vol.85 , pp. 9312-9316
    • Daley, G.Q.1    Baltimore, D.2
  • 4
    • 0025117392 scopus 로고
    • "Induction of chronic myelogenous leukemia in mice by the P210bcr/abl gene of the Philadelphia chromosome"
    • Daley, G.Q., Van Etten, R.A. and Baltimore, D. (1990) "Induction of chronic myelogenous leukemia in mice by the P210bcr/abl gene of the Philadelphia chromosome". Science, 247, 824-830.
    • (1990) Science , vol.247 , pp. 824-830
    • Daley, G.Q.1    Van Etten, R.A.2    Baltimore, D.3
  • 5
    • 0032533257 scopus 로고    scopus 로고
    • "Efficient and rapid induction of a chronic myelogenous leukemia-like myeloproliferative disease in mice receiving P210 bcr/abl-transduced bone marrow"
    • Pear, W.S., Miller, J.P., Xu, L., Pui, J.C., Soffer, B., Quackenbush, R.C., et al. (1998) "Efficient and rapid induction of a chronic myelogenous leukemia-like myeloproliferative disease in mice receiving P210 bcr/abl-transduced bone marrow", Blood, 92, 3780-3792
    • (1998) Blood , vol.92 , pp. 3780-3792
    • Pear, W.S.1    Miller, J.P.2    Xu, L.3    Pui, J.C.4    Soffer, B.5    Quackenbush, R.C.6
  • 6
    • 0030031766 scopus 로고    scopus 로고
    • "Inhibition of the Abl protein-tyrosine kinase in vitro and in vivo by a 2-phenylaminopyrimidine derivative"
    • Buchdunger, E., Zimmermann, J., Mett, H., Meyer, T., Muller, M., Druker, B.J., et al. (1996) "Inhibition of the Abl protein-tyrosine kinase in vitro and in vivo by a 2-phenylaminopyrimidine derivative", Cancer Research, 56, 100-104.
    • (1996) Cancer Research , vol.56 , pp. 100-104
    • Buchdunger, E.1    Zimmermann, J.2    Mett, H.3    Meyer, T.4    Muller, M.5    Druker, B.J.6
  • 7
    • 0029947186 scopus 로고    scopus 로고
    • "Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells"
    • Druker, B.J., Tamura, S., Buchdunger, E., Ohno, S., Segal, G.M., Fanning, S., et al. (1996) "Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells", Nature Medicine, 2, 561-566.
    • (1996) Nature Medicine , vol.2 , pp. 561-566
    • Druker, B.J.1    Tamura, S.2    Buchdunger, E.3    Ohno, S.4    Segal, G.M.5    Fanning, S.6
  • 8
    • 0034254249 scopus 로고    scopus 로고
    • "Inhibition of c-kit receptor tyrosine kinase activity by STI 571, a selective tyrosine kinase inhibitor"
    • Heinrich, M.C., Griffith, D.J., Druker, B.J., Wait, C.L., Ott, K.A. and Zigler, A.J. (2000) "Inhibition of c-kit receptor tyrosine kinase activity by STI 571, a selective tyrosine kinase inhibitor", Blood, 96, 925-932.
    • (2000) Blood , vol.96 , pp. 925-932
    • Heinrich, M.C.1    Griffith, D.J.2    Druker, B.J.3    Wait, C.L.4    Ott, K.A.5    Zigler, A.J.6
  • 9
    • 0031454003 scopus 로고    scopus 로고
    • "CGP 57148, a tyrosine kinase inhibitor, inhibits the growth of cells expressing BCR-ABL, TEL-ABL, and TEL-PDGFR fusion proteins"
    • Carroll, M., Ohno-Jones, S., Tamura, S., Buchdunger, E., Zimmermann, J., Lydon, N.B., et al. (1997) "CGP 57148, a tyrosine kinase inhibitor, inhibits the growth of cells expressing BCR-ABL, TEL-ABL, and TEL-PDGFR fusion proteins", Blood, 90, 4947-4952.
    • (1997) Blood , vol.90 , pp. 4947-4952
    • Carroll, M.1    Ohno-Jones, S.2    Tamura, S.3    Buchdunger, E.4    Zimmermann, J.5    Lydon, N.B.6
  • 11
    • 0030853063 scopus 로고    scopus 로고
    • "The tyrosine kinase inhibitor CGP57148B selectively inhibits the growth of BCR-ABL-positive cells"
    • Deininger, M.W., Goldman, J.M., Lydon, N. and Melo, J.V. (1997) "The tyrosine kinase inhibitor CGP57148B selectively inhibits the growth of BCR-ABL-positive cells", Blood, 90, 3691-3698.
    • (1997) Blood , vol.90 , pp. 3691-3698
    • Deininger, M.W.1    Goldman, J.M.2    Lydon, N.3    Melo, J.V.4
  • 12
    • 0035810147 scopus 로고    scopus 로고
    • "Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia"
    • Druker, B.J., Talpaz, M., Resta, D.J., Peng, B., Buchdunger, E., Ford, J.M., et al. (2001) "Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia", New England Journal of Medicine, 344, 1031-1037.
    • (2001) New England Journal of Medicine , vol.344 , pp. 1031-1037
    • Druker, B.J.1    Talpaz, M.2    Resta, D.J.3    Peng, B.4    Buchdunger, E.5    Ford, J.M.6
  • 13
    • 0035810142 scopus 로고    scopus 로고
    • "Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome"
    • Druker, B.J., Sawyers, C.L., Kantarjian, H., Resta, D.J., Reese, S.F., Ford, J.M., (2001) "Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome". New England Journal of Medicine, 344, 1038-1042.
    • (2001) New England Journal of Medicine , vol.344 , pp. 1038-1042
    • Druker, B.J.1    Sawyers, C.L.2    Kantarjian, H.3    Resta, D.J.4    Reese, S.F.5    Ford, J.M.6
  • 14
    • 10744233716 scopus 로고    scopus 로고
    • "Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia"
    • O'Brien, S.G., Guilhot, F., Larson, R.A., Gathmann, I., Baccarani, M., Cervantes, F., et al. (2003) "Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia", New England Journal of Medicine, 348, 994-1004.
    • (2003) New England Journal of Medicine , vol.348 , pp. 994-1004
    • O'Brien, S.G.1    Guilhot, F.2    Larson, R.A.3    Gathmann, I.4    Baccarani, M.5    Cervantes, F.6
  • 15
    • 0034018326 scopus 로고    scopus 로고
    • "The tyrosine kinase inhibitor STI571, like interferon-alpha, preferentially reduces the capacity for amplification of granulocyte- macrophage progenitors from patients with chronic myeloid leukemia"
    • Marley, S.B., Deininger, M.W., Davidson, R.J., Goldman, J.M. and Gordon, M.Y. (2000) "The tyrosine kinase inhibitor STI571, like interferon-alpha, preferentially reduces the capacity for amplification of granulocyte- macrophage progenitors from patients with chronic myeloid leukemia", Experimental Hematology, 28, 551-557.
    • (2000) Experimental Hematology , vol.28 , pp. 551-557
    • Marley, S.B.1    Deininger, M.W.2    Davidson, R.J.3    Goldman, J.M.4    Gordon, M.Y.5
  • 16
    • 0032529110 scopus 로고    scopus 로고
    • "Treatment with interferon-alpha preferentially reduces the capacity for amplification of granulocyte-macrophage progenitors (CFU-GM) from patients with chronic myeloid leukemia but spares normal CFU-GM"
    • Gordon, M.Y., Marley, S.B., Lewis, J.L., Davidson, R.J., Nguyen, D.X., Grand, F.H., et al. (1998) "Treatment with interferon-alpha preferentially reduces the capacity for amplification of granulocyte-macrophage progenitors (CFU-GM) from patients with chronic myeloid leukemia but spares normal CFU-GM", Journal of Clinical Investigation, 102, 710-715.
    • (1998) Journal of Clinical Investigation , vol.102 , pp. 710-715
    • Gordon, M.Y.1    Marley, S.B.2    Lewis, J.L.3    Davidson, R.J.4    Nguyen, D.X.5    Grand, F.H.6
  • 17
    • 0034796301 scopus 로고    scopus 로고
    • "Progenitor cells from patients with advanced phase chronic myeloid leukaemia respond to STI571 in vitro and in vivo"
    • Marley, S.B., Davidson, R.J., Lewis, J.L., Nguyen, D.X., Eades, A., Parker, S., et al. (2001) "Progenitor cells from patients with advanced phase chronic myeloid leukaemia respond to STI571 in vitro and in vivo", Leukaemia Research, 25, 997-1002.
    • (2001) Leukaemia Research , vol.25 , pp. 997-1002
    • Marley, S.B.1    Davidson, R.J.2    Lewis, J.L.3    Nguyen, D.X.4    Eades, A.5    Parker, S.6
  • 18
    • 0032859309 scopus 로고    scopus 로고
    • "Favorable therapeutic index of a p210(BCR-ABL)-specific tyrosine kinase inhibitor; activity on lineage-committed and primitive chronic myelogenous leukemia progenitors"
    • Kasper, B., Fruehauf, S., Schiedlmeier, B., Buchdunger, E., Ho, A.D. and Zeller, W.J. (1999) "Favorable therapeutic index of a p210(BCR-ABL)-specific tyrosine kinase inhibitor; activity on lineage-committed and primitive chronic myelogenous leukemia progenitors", Cancer Chemotherapy Pharmacology, 44, 433-438.
    • (1999) Cancer Chemotherapy Pharmacology , vol.44 , pp. 433-438
    • Kasper, B.1    Fruehauf, S.2    Schiedlmeier, B.3    Buchdunger, E.4    Ho, A.D.5    Zeller, W.J.6
  • 19
    • 0037093082 scopus 로고    scopus 로고
    • "Imatinib mesylate (STI571) inhibits growth of primitive malignant progenitors in chronic myelogenous leukemia through reversal of abnormally increased proliferation"
    • Holtz, M.S., Slovak, M.L., Zhang, F., Sawyers, C.L., Forman, S.J. and Bhatia, R. (2002) "Imatinib mesylate (STI571) inhibits growth of primitive malignant progenitors in chronic myelogenous leukemia through reversal of abnormally increased proliferation", Blood, 99, 3792-3800.
    • (2002) Blood , vol.99 , pp. 3792-3800
    • Holtz, M.S.1    Slovak, M.L.2    Zhang, F.3    Sawyers, C.L.4    Forman, S.J.5    Bhatia, R.6
  • 20
    • 0036090222 scopus 로고    scopus 로고
    • "Primitive, quiescent, Philadelphia-positive stem cells from patients with chronic myeloid leukemia are insensitive to STI571 in vitro"
    • Graham, S.M., Jorgensen, H.G., Allan, E., Pearson, C., Alcorn, M.J., Richmond, L., et al. (2002) "Primitive, quiescent, Philadelphia-positive stem cells from patients with chronic myeloid leukemia are insensitive to STI571 in vitro", Blood, 99, 319-325.
    • (2002) Blood , vol.99 , pp. 319-325
    • Graham, S.M.1    Jorgensen, H.G.2    Allan, E.3    Pearson, C.4    Alcorn, M.J.5    Richmond, L.6
  • 21
    • 0034689031 scopus 로고    scopus 로고
    • "Blockade of the Bcr-Abl kinase activity induces apoptosis of chronic myelogenous leukemia cells by suppressing signal transducer and activator of transcription 5-dependent expression of Bcl-xL"
    • Horita, M., Andreu, E.J., Benito, A., Athena, C., Sanz, C., Benet, I. et al. (2000) "Blockade of the Bcr-Abl kinase activity induces apoptosis of chronic myelogenous leukemia cells by suppressing signal transducer and activator of transcription 5-dependent expression of Bcl-xL", Journal of Experimental Medicine, 191, 977-984.
    • (2000) Journal of Experimental Medicine , vol.191 , pp. 977-984
    • Horita, M.1    Andreu, E.J.2    Benito, A.3    Athena, C.4    Sanz, C.5    Benet, I.6
  • 22
    • 0038454621 scopus 로고    scopus 로고
    • "Persistence of malignant hematopoietic progenitors in chronic myelogenous leukemia patients in complete cytogenetic remission following imatinib mesylate treatment"
    • Bhatia, R., Holtz, M., Niu, N., Gray, R., Snyder, D.S., Sawyers, C.L., et al. (2003) "Persistence of malignant hematopoietic progenitors in chronic myelogenous leukemia patients in complete cytogenetic remission following imatinib mesylate treatment", Blood, 101, 4701-4707.
    • (2003) Blood , vol.101 , pp. 4701-4707
    • Bhatia, R.1    Holtz, M.2    Niu, N.3    Gray, R.4    Snyder, D.S.5    Sawyers, C.L.6
  • 23
    • 0035525787 scopus 로고    scopus 로고
    • "Establishment of a murine model for therapy-treated chronic myelogenous leukemia using the tyrosine kinase inhibitor STI571"
    • Wolff, N.C. and Ilaria, R. L., Jr. (2001) "Establishment of a murine model for therapy-treated chronic myelogenous leukemia using the tyrosine kinase inhibitor STI571", Blood, 98, 2808-2816.
    • (2001) Blood , vol.98 , pp. 2808-2816
    • Wolff, N.C.1    Ilaria Jr., R.L.2
  • 24
    • 0036850514 scopus 로고    scopus 로고
    • "Molecular and chromosomal mechanisms of resistance to imatinib (STI571) therapy"
    • Hochhaus, A., Kreil, S., Corbin, A.S., La Rosee, P., Muller, M.C., Lahaye, T., et al. (2002) "Molecular and chromosomal mechanisms of resistance to imatinib (STI571) therapy", Leukemia, 16, 2190-2196.
    • (2002) Leukemia , vol.16 , pp. 2190-2196
    • Hochhaus, A.1    Kreil, S.2    Corbin, A.S.3    La Rosee, P.4    Muller, M.C.5    Lahaye, T.6
  • 25
    • 0035800507 scopus 로고    scopus 로고
    • "Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification"
    • Gorre, M.E., Mohammed, M., Ellwood, K., Hsu, N., Paquette, R., Rao, P.N., et al. (2001) "Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification", Science, 293, 876-880.
    • (2001) Science , vol.293 , pp. 876-880
    • Gorre, M.E.1    Mohammed, M.2    Ellwood, K.3    Hsu, N.4    Paquette, R.5    Rao, P.N.6
  • 26
    • 0001686739 scopus 로고    scopus 로고
    • "Multiple BCR-ABL kinase domain mutations confer polyclonal resistance to the tyrosine kinase inhibitor imatinib (STI571) in chronic phase and blast crisis chronic myeloid leukemia"
    • Shah, N.P., Nicoll, J.M., Nagar, B., Gorre, M.E., Paquette, R.L., Kuriyan, J., et al. (2002) "Multiple BCR-ABL kinase domain mutations confer polyclonal resistance to the tyrosine kinase inhibitor imatinib (STI571) in chronic phase and blast crisis chronic myeloid leukemia", Cancer Cell, 2, 117-125.
    • (2002) Cancer Cell , vol.2 , pp. 117-125
    • Shah, N.P.1    Nicoll, J.M.2    Nagar, B.3    Gorre, M.E.4    Paquette, R.L.5    Kuriyan, J.6
  • 27
    • 0037045583 scopus 로고    scopus 로고
    • "BCR-ABL gene mutations in relation to clinical resistance of Philadelphia-chromosome-positive leukaemia to STI571: A prospective study"
    • [comment]
    • von Bubnoff, N., Schneller, F., Peschel, C. and Duyster, J. (2002) "BCR-ABL gene mutations in relation to clinical resistance of Philadelphia-chromosome-positive leukaemia to STI571: a prospective study. [comment]", Lancet, 359, 487-491.
    • (2002) Lancet , vol.359 , pp. 487-491
    • von Bubnoff, N.1    Schneller, F.2    Peschel, C.3    Duyster, J.4
  • 28
    • 0036682481 scopus 로고    scopus 로고
    • "Several types of mutations of the AN gene can be found in chronic myeloid leukemia patients resistant to STI571, and they can pre-exist to the onset of treatment"
    • Roche-Lestienne, C., Soenen-Cornu, V., Grardel-Duflos, N., Lai, J.L., Philippe, N., Facon, T., et al. (2002) "Several types of mutations of the AN gene can be found in chronic myeloid leukemia patients resistant to STI571, and they can pre-exist to the onset of treatment", Blood, 100, 1014-1018.
    • (2002) Blood , vol.100 , pp. 1014-1018
    • Roche-Lestienne, C.1    Soenen-Cornu, V.2    Grardel-Duflos, N.3    Lai, J.L.4    Philippe, N.5    Facon, T.6
  • 30
    • 0029842452 scopus 로고    scopus 로고
    • "Primitive human hematopoietic cells displaying differential efflux of the rhodamine 123 dye have distinct biological activities"
    • Uchida, N., Combs, J., Chen, S., Zanjani, E., Hoffman, R. and Tsukamoto, A. (1996) "Primitive human hematopoietic cells displaying differential efflux of the rhodamine 123 dye have distinct biological activities", Blood, 88, 1297-1305.
    • (1996) Blood , vol.88 , pp. 1297-1305
    • Uchida, N.1    Combs, J.2    Chen, S.3    Zanjani, E.4    Hoffman, R.5    Tsukamoto, A.6
  • 31
    • 0029958876 scopus 로고    scopus 로고
    • "Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo"
    • Goodell, M.A., Brose, K., Paradis, G., Conner, A.S. and Mulligan, R.C. (1996) "Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo", Journal of Experimental Medicine, 183, 1797-1806.
    • (1996) Journal of Experimental Medicine , vol.183 , pp. 1797-1806
    • Goodell, M.A.1    Brose, K.2    Paradis, G.3    Conner, A.S.4    Mulligan, R.C.5
  • 32
    • 0031435428 scopus 로고    scopus 로고
    • "Dye efflux studies suggest that hematopoietic stem cells expressing low or undetectable levels of CD34 antigen exist in multiple species"
    • Goodell, M.A., Rosenzweig, M., Kim, H., Marks, D.F., DeMaria, M., Paradis, G., et al. (1997) "Dye efflux studies suggest that hematopoietic stem cells expressing low or undetectable levels of CD34 antigen exist in multiple species", Nature Medicine, 3, 1337-1345.
    • (1997) Nature Medicine , vol.3 , pp. 1337-1345
    • Goodell, M.A.1    Rosenzweig, M.2    Kim, H.3    Marks, D.F.4    DeMaria, M.5    Paradis, G.6
  • 33
    • 0037079708 scopus 로고    scopus 로고
    • "The ABCG2 transporter is an efficient Hoechst 33342 efflux pump and is preferentially expressed by immature human hematopoietic progenitors"
    • Scharenberg, C.W., Harkey, M.A. and Torok-Storb, B. (2002) "The ABCG2 transporter is an efficient Hoechst 33342 efflux pump and is preferentially expressed by immature human hematopoietic progenitors", Blood, 99, 507-512.
    • (2002) Blood , vol.99 , pp. 507-512
    • Scharenberg, C.W.1    Harkey, M.A.2    Torok-Storb, B.3
  • 34
    • 0036940590 scopus 로고    scopus 로고
    • "Drug responses of imatinib mesylateresistant cells: Synergism of imatinib with other chemotherapeutic drugs"
    • Tipping, A.J., Mahon, F.X., Zafirides, G., Lagarde, V., Goldman, J.M. and Melo, J.V. (2002) "Drug responses of imatinib mesylateresistant cells: synergism of imatinib with other chemotherapeutic drugs", Leukemia, 16, 2349-2357.
    • (2002) Leukemia , vol.16 , pp. 2349-2357
    • Tipping, A.J.1    Mahon, F.X.2    Zafirides, G.3    Lagarde, V.4    Goldman, J.M.5    Melo, J.V.6
  • 35
    • 0034330931 scopus 로고    scopus 로고
    • "Efficacy of STI571, an abl tyrosine kinase inhibitor, in conjunction with other antileukemic agents against bcr-abl-positive cells"
    • Thiesing, J.T., Ohno-Jones, S., Kolibaba, K.S. and Druker, B.J. (2000) "Efficacy of STI571, an abl tyrosine kinase inhibitor, in conjunction with other antileukemic agents against bcr-abl-positive cells", Blood, 96, 3195-3199.
    • (2000) Blood , vol.96 , pp. 3195-3199
    • Thiesing, J.T.1    Ohno-Jones, S.2    Kolibaba, K.S.3    Druker, B.J.4
  • 36
    • 0037094118 scopus 로고    scopus 로고
    • "In vitro effects of STI 571-containing drug combinations on the growth of Philadelphia-positive chronic myelogenous leukemia cells"
    • Scappini, B., Onida, F., Kantarjian, H.M., Dong, L., Verstovsek, S., Keating, M.J., et al. (2002) "In vitro effects of STI 571-containing drug combinations on the growth of Philadelphia-positive chronic myelogenous leukemia cells", Cancer, 94, 2653-2662.
    • (2002) Cancer , vol.94 , pp. 2653-2662
    • Scappini, B.1    Onida, F.2    Kantarjian, H.M.3    Dong, L.4    Verstovsek, S.5    Keating, M.J.6
  • 37
    • 0036159844 scopus 로고    scopus 로고
    • "Effects of combinations of therapeutic agents on the proliferation of progenitor cells in chronic myeloid leukaemia"
    • Marley, S.B., Davidson, R.J., Goldman, J.M. and Gordon, M.Y. (2002) "Effects of combinations of therapeutic agents on the proliferation of progenitor cells in chronic myeloid leukaemia", British Journal of Haematology, 116, 162-165.
    • (2002) British Journal of Haematology , vol.116 , pp. 162-165
    • Marley, S.B.1    Davidson, R.J.2    Goldman, J.M.3    Gordon, M.Y.4
  • 38
    • 0036320754 scopus 로고    scopus 로고
    • "In vitro studies of the combination of imatinib mesylate (Gleevec) and arsenic trioxide (Trisenox) in chronic myelogenous leukemia"
    • La Rosee, P., Johnson, K., O'Dwyer, M.E. and Druker, B.J. (2002) "In vitro studies of the combination of imatinib mesylate (Gleevec) and arsenic trioxide (Trisenox) in chronic myelogenous leukemia", Experimental Hematology, 30, 729-737.
    • (2002) Experimental Hematology , vol.30 , pp. 729-737
    • La Rosee, P.1    Johnson, K.2    O'Dwyer, M.E.3    Druker, B.J.4
  • 39
    • 0036683409 scopus 로고    scopus 로고
    • "Overcoming STI571 resistance with the farnesyl transferase inhibitor SCH66336"
    • Hoover, R.R., Mahon, F.X., Melo, J.V. and Daley, G.Q. (2002) "Overcoming STI571 resistance with the farnesyl transferase inhibitor SCH66336", Blood, 100, 1068-1071.
    • (2002) Blood , vol.100 , pp. 1068-1071
    • Hoover, R.R.1    Mahon, F.X.2    Melo, J.V.3    Daley, G.Q.4
  • 40
    • 0037194613 scopus 로고    scopus 로고
    • "Phosphatidylinositol-3 kinase inhibitors enhance the anti-leukemia effect of STI571"
    • Klejman, A., Rushen, L., Morrione, A., Slupianek, A. and Skorski, T. (2002) "Phosphatidylinositol-3 kinase inhibitors enhance the anti-leukemia effect of STI571", Oncogene, 21, 5868-5876.
    • (2002) Oncogene , vol.21 , pp. 5868-5876
    • Klejman, A.1    Rushen, L.2    Morrione, A.3    Slupianek, A.4    Skorski, T.5
  • 41
    • 0037108879 scopus 로고    scopus 로고
    • "Molecular characterization and sensitivity of STI-571 (imatinib mesylate, Gleevec)-resistant, Bcr-Abl-positive, human acute leukemia cells to SRC kinase inhibitor PD180970 and 17-allylamino-17-demethoxygeldanamycin"
    • Nimmanapalli, R., O'Bryan, E., Huang, M., Bali, P., Burnette, P.K., Loughran, T., et al. (2002) "Molecular characterization and sensitivity of STI-571 (imatinib mesylate, Gleevec)-resistant, Bcr-Abl-positive, human acute leukemia cells to SRC kinase inhibitor PD180970 and 17-allylamino-17-demethoxygeldanamycin", Cancer Research, 62, 5761-5769.
    • (2002) Cancer Research , vol.62 , pp. 5761-5769
    • Nimmanapalli, R.1    O'Bryan, E.2    Huang, M.3    Bali, P.4    Burnette, P.K.5    Loughran, T.6
  • 42
    • 0037115644 scopus 로고    scopus 로고
    • "Activity of the Bcr-Abl kinase inhibitor PD180970 against clinically relevant Bcr-Abl isoforms that cause resistance to imatinib mesylate (Gleevec, STI571)"
    • La Rosee, P., Corbin, A.S., Stoffregen, E.P., Deminger, M.W. and Druker, B.J. (2002) "Activity of the Bcr-Abl kinase inhibitor PD180970 against clinically relevant Bcr-Abl isoforms that cause resistance to imatinib mesylate (Gleevec, STI571)", Cancer Research, 62, 7149-7153.
    • (2002) Cancer Research , vol.62 , pp. 7149-7153
    • La Rosee, P.1    Corbin, A.S.2    Stoffregen, E.P.3    Deminger, M.W.4    Druker, B.J.5
  • 43
    • 0037069942 scopus 로고    scopus 로고
    • "Inhibition of Bcr-Abl kinase activity by PD180970 blocks constitutive activation of Stat5 and growth of CML cells"
    • Huang, M., Dorsey, J.F., Epling-Burnette, P.K., Nimmanapalli, R., Landowski, T.H., Mora, L.B., et al. (2002) "Inhibition of Bcr-Abl kinase activity by PD180970 blocks constitutive activation of Stat5 and growth of CML cells", Oncogene, 21, 8804-8816.
    • (2002) Oncogene , vol.21 , pp. 8804-8816
    • Huang, M.1    Dorsey, J.F.2    Epling-Burnette, P.K.3    Nimmanapalli, R.4    Landowski, T.H.5    Mora, L.B.6
  • 44
    • 0036682230 scopus 로고    scopus 로고
    • "Characterization of potent inhibitors of the Bcr-Abl and the c-kit receptor tyrosine kinases"
    • Wisniewski, D., Lambek, C.L., Liu, C., Strife, A., Veach, D.R., Nagar, B., et al. (2002) "Characterization of potent inhibitors of the Bcr-Abl and the c-kit receptor tyrosine kinases", Cancer Research, 62, 4244-4255.
    • (2002) Cancer Research , vol.62 , pp. 4244-4255
    • Wisniewski, D.1    Lambek, C.L.2    Liu, C.3    Strife, A.4    Veach, D.R.5    Nagar, B.6
  • 45
    • 0034308176 scopus 로고    scopus 로고
    • "Biochemical and cellular effects of c-Src kinase-selective pyrido[2, 3-d]pyrimidine tyrosine kinase inhibitors"
    • Kraker, A.J., Hartl, B.G., Amar, A.M., Barvian, M.R., Showalter, H.D. and Moore, C.W. (2000) "Biochemical and cellular effects of c-Src kinase-selective pyrido[2, 3-d]pyrimidine tyrosine kinase inhibitors", Biochemical Pharmacology, 60, 885-898.
    • (2000) Biochemical Pharmacology , vol.60 , pp. 885-898
    • Kraker, A.J.1    Hartl, B.G.2    Amar, A.M.3    Barvian, M.R.4    Showalter, H.D.5    Moore, C.W.6


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