The isoflavonoids genistein and quercetin activate different stress signaling pathways as shown by analysis of site-specific phosphorylation of ATM, p53 and histone H2AX

DNA Repair

Volumn 3, Issue 3, 2004, Pages 235-244

  Ye, Ruiqiong ^a   Goodarzi, Aaron A ^a   Kurz, Ebba U ^a   Saito, Shin'Ichi ^b   Higashimoto, Yuichiro ^b,e   Lavin, Martin F ^c   Appella, Ettore ^b   Anderson, Carl W ^d   Lees Miller, Susan P ^a  

^a UNIVERSITY OF CALGARY   (Canada)

^b NATIONAL CANCER INSTITUTE   (United States)

^c ROYAL BRISBANE AND WOMEN'S HOSPITAL   (Australia)

^d BROOKHAVEN NATIONAL LABORATORY   (United States)

^e KURUME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

DNA damage; Genistein; Isoflavonoid; p53; Phosphorylation; Quercetin

Indexed keywords

ATM PROTEIN; BIOCHANIN A; BIOFLAVONOID; DAIDZEIN; GENISTEIN; HISTONE H2A; ISOFLAVONOID; ISOPROTEIN; PROTEIN P53; QUERCETIN; SERINE;

ARTICLE; CELL LINE; CONTROLLED STUDY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; STRESS;

ATAXIA; ATAXIA TELANGIECTASIA;

EID: 0842303315     PISSN: 15687864     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.dnarep.2003.10.014     Document Type: Article

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