Influence of Promoter Variants of Interleukin-10, Interleukin-9, and Tumor Necrosis Factor-α Genes on Respiratory Syncytial Virus Bronchiolitis

Journal of Infectious Diseases

Volumn 189, Issue 2, 2004, Pages 239-247

  Hoebee, Barbara ^a   Bont, Louis ^b   Rietveld, Edwin ^c   Van Oosten, Marijke ^a   Hodemaekers, Hennie M ^a   Nagelkerke, Nico J D ^a   Neijens, Herman J ^c   Kimpen, Jan L L ^b   Kimman, Tjeerd G ^a  

^a NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^c SOPHIA CHILDREN S HOSPITAL   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 10; INTERLEUKIN 9; TUMOR NECROSIS FACTOR ALPHA;

ALLELE; ARTICLE; BRONCHIOLITIS; CHILD; CHILD HOSPITALIZATION; CONFIDENCE INTERVAL; CONTROLLED STUDY; GENE INTERACTION; GENE LINKAGE DISEQUILIBRIUM; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC VARIABILITY; HETEROZYGOTE; HIGH RISK POPULATION; HOMOZYGOSITY; HUMAN; INFANT; INFECTION RISK; MAJOR CLINICAL STUDY; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; STATISTICAL SIGNIFICANCE; VIRUS TRANSMISSION;

ADULT; BRONCHIOLITIS; CHILD; GENOTYPE; HUMANS; INTERLEUKIN-10; INTERLEUKIN-4; INTERLEUKIN-9; POLYMORPHISM, GENETIC; PROMOTER REGIONS (GENETICS); RECEPTORS, INTERLEUKIN-4; RESPIRATORY SYNCYTIAL VIRUS INFECTIONS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0742272598     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/380908     Document Type: Article

References (56)

1. Hoebee B, Rietveld E, Bont L, et al. Association of severe respiratory syncytial virus bronchiolitis with interleukin-4 and interleukin-4 receptor α polymorphisms. J Infect Dis 2003; 187:2-11.
2. Hull J, Thomson A, Kwiatkowski D. Association of respiratory syncytial virus bronchiolitis with the interleukin 8 gene region in UK families. Thorax 2000; 55:1023-7.
3. Hull J, Ackerman H, Isles K, et al. Unusual haplotypic structure of IL8, a susceptibility locus for a common respiratory virus. Am J Hum Genet 2001; 69:413-9.
4. Lahti M, Lofgren J, Marttila R, et al. Surfactant protein D gene polymorphism associated with severe respiratory syncytial virus infection. Pediatr Res 2002; 51:696-9.
5. Lofgren J, Ramet M, Renko M, Marttila R, Hallman M. Association between surfactant protein A gene locus and severe respiratory syncytial virus infection in infants. J Infect Dis 2002; 185:283-9.
6. Choi EH, Lee HJ, Yoo T, Chanock SJ. A common haplotype of interleukin-4 gene IL4 is associated with severe respiratory syncytial virus disease in Korean children. J Infect Dis 2002; 186:1207-11.
7. Gentile DA, Doyle WJ, Zeevi A, et al. Cytokine gene polymorphisms moderate illness severity in infants with respiratory syncytial virus infection. Hum Immunol 2003; 64:338-44.
8. Hoffjan S, Ober C. Present status on the genetic studies of asthma. Curr Opin Immunol 2002; 14:709-17.
9. Kelleher K, Bean K, Clark SC, et al. Human interleukin-9: genomic sequence, chromosomal location, and sequences essential for its expression in human T-cell leukemia virus (HTLV)-I-transformed human T cells. Blood 1991; 77:1436-41.
10. Wilson AG, de Vries N, Pociot F, di Giovine FS, van der Putte LBA, Duff GW. An allelic polymorphism within the human tumor necrosis factor α promoter region is strongly associated with HLA A1, B8 and DR3 alleles. J Exp Med 1993; 177:557-60.
11. Takashiba S, Shapira L, Amar S, Van Dyke TE. Cloning and characterization of human TNF alpha promoter region. Gene 1993; 131:307-8.
12. Sham PC. Statistics in human genetics. London: Arnold, 1998.
13. Whittemore AS, Tu IP. Detection of disease genes by use of family data. I. Likelihood-based theory. Am J Hum Genet 2000; 66:1328-40.
14. Tu IP, Balise RR, Whittemore AS. Detection of disease genes by use of family data. II. Application to nuclear families. Am J Hum Genet 2000; 66:1341-50.
15. Openshaw PJ, Pemberton RM, Ball LA, Wertz GW, Askonas BA. Helper T cell recognition of respiratory syncytial virus in mice. J Gen Virol 1988; 69:305-12.
16. Connors M, Giese NA, Kulkarni AB, Firestone C, Morse HC, Murphy BR. Enhanced pulmonary histopathology induced by respiratory syncytial virus (RSV) challenge of formalin-inactivated RSV-immunized BALB/c mice is abrogated by depletion of interieukin-4 (IL-4) and IL-19. J Virol 1994; 68:5321-5.
17. Boelen A, Andeweg A, Kwakkel J, et al. Both immunisation with a formalin-inactivated respiratory syncytial virus (RSV) vaccine and a mock antigen vaccine induce severe lung pathology and a Th2 cytokine profile in RSV-challenged mice. Vaccine 2000; 19:982-91.
18. Bendelja K, Gagro K, Bace A, et al. Predominant type-2 response in infants with respiratory syncytial virus (RSV) infection demonstrated by cytokine flow cytometry. Clin Exp Immunol 2000; 121:332-8.
19. + B cells in infants with bronchiolitis is accompanied by appearance of IgE and IgG4 antibodies specific for respiratory syncytial virus. J Infect Dis 1997; 175:32-7.
20. Roman M, Calhoen WJ, Himton KL. Respiratory syncytial virus infection in infants is associated with predominant Th-2 like response. Am J Respir Crit Care Med 1997; 156:190-5.
21. Tripp RA, Moore, D, Barskey A 4th, et al. Peripheral blood mononuclear cells from infants hospitalized because of respiratory syncytial virus infection express T helper-1 and T helper-2 cytokines and CC chemokine messenger RNA. J Infect Dis 2002; 185:1388-94.
22. Bont L, Heijnen CJ, Kavelaars A, et al. Peripheral blood cytokine responses and disease severity in respiratory syncytial virus bronchiolitis. Eur Respir J 1999; 14:144-9.
23. Hobbs K, Negri J, Klinnert M, Rosenwasser LJ, Borish L. Interleukin-10 and transforming growth factor-β promoter polymorphisms in allergies and asthma. Am J Respir Crit Care Med 1998; 158:1958-62.
24. Bidwell J, Keen L, Gallagher G, et al. Cytokine gene polymorphism in human disease: on-line databases. Genes Immun 1999; 1:3-19.
25. Bidwell J, Keen L, Gallagher G, et al. Cytokine gene polymorphism in human disease: on-line databases, supplement 1. Genes Immun 2001; 2:61-70.
26. Haukim N, Bidwell JL, Smith AJ, et al. Cytokine gene polymorphism in human disease: on-line databases, supplement 2. Genes Immun 2002; 3:313-30.
27. Rosenwasser L. Promoter polymorphism in the candidate genes, IL-4, IL-9, TGF-β1, for atopy and asthma. Int Arch Allergy Immunol 1999; 118:268-70.
28. Opal SM, Huber CE. The role of interleukin-10 in critical illness. Curr Opin Infect Dis 2000; 13:221-6.
29. Moore KW, de Waal Malefyt R, Coffman RL, O'Garra A. Interleukin-10 and the interleukin-10 receptor. Annu Rev Immunol 2001; 19:683-765.
30. Redpath S, Ghazal P, Gascoigne NR. Hijacking and exploitation of IL-10 by intracellular pathogens. Trends Microbiol 2001; 9:86-92.
31. Kim JM, Brannan CI, Copeland NG, Jenkins NA, Khan TA, Moore KW. Structure of the mouse IL-10 gene and chromosomal localization of the mouse and human genes. J Immunol 1992; 148:3618-23.
32. Eskdale J, Kube D, Tesch H, Gallagher G. Mapping of the human IL10 gene and further characterization of the 5′ flanking sequence. Immunogenetics 1997; 46:120-8.
33. Turner DM, Williams DM, Sankaran D, Lazarus M, Sinnott PJ, Hutchinson IV. An investigation of polymorphism in the interleukin-10 gene promoter. Eur J Immunogenet 1997; 24:1-8.
34. Crawley E, Kay R, Sillibourne J, Patel P, Hutchinson I, Woo P. Polymorphic haplotypes of the interleukin-10 5′ flanking region determine variable interleukin-10 transcription and are associated with particular phenotypes of juvenile rheumatoid arthritis. Arthritis Rheum 1999; 42:1101-8.
35. Cartwright NH, Keen LJ, Demaine AG, et al. A study of cytokine gene polymorphisms and protein secretion in renal transplantation. Transpl Immunol 2001; 8:237-44.
36. Helminen ME, Kilpinen S, Virta M, Hurme M. Susceptibility to primary Epstein-Barr virus infection is associated with interleukin-10 gene promoter polymorphism. J Infect Dis 2001; 184:777-80.
37. Warle MC, Farhan A, Metselaar HJ, et al. Are cytokine gene polymorphisms related to in vitro cytokine production profiles? Liver Transpl 2003; 9:170-81.
38. Suarez A, Castro P, Alonso R, Mozo L, Gutierrez C. Interindividual variations in constitutive interleukin-10 messenger RNA and protein levels and their association with genetic polymorphisms. Transplantation 2003; 75:711-7.
39. Reuss E, Fimmers R, Kruger A, Becker C, Rittner C, Hohler T. Differential regulation of interleukin-10 production by genetic and environmental factors - a twin study. Genes Immun 2002; 3:407-13.
40. Howell WM, Turner SJ, Bateman AC, Theaker JM. IL-10 promoter polymorphisms influence tumour development in cutaneous malignant melanoma. Genes Immun 2001; 2:25-31.
41. Koss K, Fanning GC, Welsh KI, Jewell DP. Interleukin-10 gene promoter polymorphism in English and Polish healthy controls: polymerase chain reaction haplotyping using 3′ mismatches in forward and reverse primers. Genes Immun 2000; 1:321-4.
42. Crowe JE Jr. Immune responses of infants to infection with respiratory viruses and live attenuated respiratory virus candidate vaccines. Vaccine 1998; 16:1423-32.
43. Vigano A, Esposito S, Arienti D, et al. Differential development of type 1 and type 2 cytokines and β-chemokines in the ontogeny of healthy newborns. Biol Neonate 1999; 75:1-8.
44. Prescott SL, Macaubas C, Smallacombe T, Holt BJ, Sly PD, Holt PG. Development of allergen-specific T-cell memory in atopic and normal children. Lancet 1999; 353:196-200.
45. Demoulin JB, Renauld JC. Interleukin 9 and its receptor: an overview of structure and function. Int Rev Immunol 1998; 16:345-64.
46. Soussi-Gounni A, Kontolemos M, Hamid Q. Role of IL-9 in the pathophysiology of allergic diseases. J Allergy Clin Immunol 2001; 107:575-82.
47. Louahed J, Toda M, Jen J, et al. Interleukin-9 upregulates mucus expression in the airways. Am J Respir Cell Mol Biol 2000; 22:649-56.
48. Temann UA, Geba GP, Rankin JA, Flavell RA. Expression of interleukin 9 in the lungs of transgenic mice causes airway inflammation, mast cell hyperplasia, and bronchial hyperresponsiveness. J Exp Med 1998; 188:1307-20.
49. McLane MP, Haczku A, van de Rijn M, et al. Interleukin-9 promotes allergen-induced eosinophilic inflammation and airway hyperresponsiveness in transgenic mice. Am J Respir Cell Mol Biol 1998; 19:713-20.
50. Townsend JM, Fallon GP, Matthews JD, Smith P, Jolin EH, McKenzie NA. IL-9-deficient mice establish fundamental roles for IL-9 in pulmonary mastocytosis and goblet cell hyperplasia but not T cell development. Immunity 2000; 13:573-83.
51. Spies T, Morton CC, Nedospasov SA, Fiers W, Pious D, Strominger JL. Genes for the tumor necrosis factors α and α are linked to the human major histocompatibility complex. Proc Natl Acad Sci USA 1986; 83: 8699-702.
52. Wilson AG, di Giovine FS, Duff GW. Genetics of tumour necrosis factor-α in autoimmune, infectious, and neoplastic diseases. J Inflamm 1995; 45:1-12.
53. Cohn L, Homer RJ, MacLeod H, Mohrs M, Brombacher F, Bottomley K. Th2-induced airway mucus production is dependent on IL-4Rα, but not on eosinophils. J Immunol 1999; 162:6178-83.
54. Dabbagh K, Takeyama K, Lee H-M, Ueki IF, Lausier JA, Nadel JA. IL-4 induces mucin gene expression and goblet cell metaplasia in vitro and in vivo. J Immunol 1999; 162:6233-7.
55. Lee CG, Homer RJ, Cohn L, et al. Transgenic overexpression of interleukin (IL)-10 in the lung causes mucus metaplasia, tissue inflammation, and airway remodeling via IL-13-dependent and -independent pathways. J Biol Chem 2002; 277:35466-74.
56. Lang R, Patel D, Morris JJ, Rutschman RL, Murray PJ. Shaping gene expression in activated and resting primary macrophages by IL-10. J Immunol 2002; 169:2253-63.