Residues 190-210 of human topoisomerase I are required for enzyme activity in vivo but not in vitro

Nucleic Acids Research

Volumn 31, Issue 24, 2003, Pages 7255-7263

  Christensen, Morten O ^a   Barthelmes, Hans U ^a   Boege, Fritz ^a   Mielke, Christian ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CAMPTOTHECIN; DNA TOPOISOMERASE; GREEN FLUORESCENT PROTEIN;

AMINO TERMINAL SEQUENCE; ARTICLE; CELL FUNCTION; CELLULAR DISTRIBUTION; CHIMERA; CONTROLLED STUDY; COVALENT BOND; CYTOTOXICITY; DNA HELIX; DNA PROTEIN COMPLEX; DNA STRAND BREAKAGE; ENZYME ACTIVITY; ENZYME STABILITY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; PRIORITY JOURNAL; PROTEIN TRANSPORT; REGULATORY MECHANISM;

CAMPTOTHECIN; CATALYTIC DOMAIN; CELL LINE; CELL-FREE SYSTEM; DNA; DNA TOPOISOMERASES, TYPE I; DRUG RESISTANCE; HUMANS; OSMOLAR CONCENTRATION; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; SALTS; SEQUENCE DELETION;

EID: 0348149146     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/gkg927     Document Type: Article

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