메뉴 건너뛰기




Volumn 135, Issue 1, 2004, Pages 74-84

Modulation of antigen presentation by autoreactive B cell clones specific for GAD65 from a type I diabetic patient

Author keywords

Antigen specific B cells; Autoimmunity; GAD65; HLA DM; T cells

Indexed keywords

ENZYME; EPITOPE; GLUTAMATE DECARBOXYLASE 65; HLA DM ANTIGEN; UNCLASSIFIED DRUG;

EID: 0347949511     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2249.2004.02343.x     Document Type: Article
Times cited : (25)

References (34)
  • 1
    • 0029683483 scopus 로고    scopus 로고
    • Glutamic acid decarboxylase - Gene to antigen to disease
    • Lernmark A. Glutamic acid decarboxylase - gene to antigen to disease. J Int Med 1996; 240:259-77.
    • (1996) J Int Med , vol.240 , pp. 259-277
    • Lernmark, A.1
  • 2
    • 0032716704 scopus 로고    scopus 로고
    • Comparative analysts of epitope recognition of glutamic acid decarboxylase by autoantibodies from different autoimmune disorders
    • Powers AC, Bavik K, Tremble J, Daw K, Scherbaum WA, Banga JP. Comparative analysts of epitope recognition of glutamic acid decarboxylase by autoantibodies from different autoimmune disorders. Clin Exp Immunol 1999; 118:349-56.
    • (1999) Clin Exp Immunol , vol.118 , pp. 349-356
    • Powers, A.C.1    Bavik, K.2    Tremble, J.3    Daw, K.4    Scherbaum, W.A.5    Banga, J.P.6
  • 3
    • 0028943290 scopus 로고
    • Class II antigens and disease susceptibility
    • Nepom GT. Class II antigens and disease susceptibility. Ann Rev Med 1995; 46:17-25.
    • (1995) Ann Rev Med , vol.46 , pp. 17-25
    • Nepom, G.T.1
  • 4
    • 0007102288 scopus 로고    scopus 로고
    • Identification of naturally processed T cell epitopes from glutamic acid decarboxylase presented in the context of HLA-DR alleles by T lymphocytes of recent onset IDDM patients
    • Endl J, Otto H, Jung G et al. Identification of naturally processed T cell epitopes from glutamic acid decarboxylase presented in the context of HLA-DR alleles by T lymphocytes of recent onset IDDM patients. J Clin Invest 1997; 99:2405-15.
    • (1997) J Clin Invest , vol.99 , pp. 2405-2415
    • Endl, J.1    Otto, H.2    Jung, G.3
  • 5
    • 0031214615 scopus 로고    scopus 로고
    • High affinity presentation of an autoantigenic peptide in type 1 diabetes by an HLA class II protein encoded in a haplotype protecting from disease
    • Bach JM, Otto H, Nepom GT et al. High affinity presentation of an autoantigenic peptide in type 1 diabetes by an HLA class II protein encoded in a haplotype protecting from disease. J Autoimmun 1997; 10:375-86.
    • (1997) J Autoimmun , vol.10 , pp. 375-386
    • Bach, J.M.1    Otto, H.2    Nepom, G.T.3
  • 6
    • 0032979834 scopus 로고    scopus 로고
    • GAD65 reactive T cells in a non-diabetic stiff-man syndrome patient
    • Schloot NC, Batstra MC, Duinkerken G et al. GAD65 reactive T cells in a non-diabetic stiff-man syndrome patient. J Autoimmun 1999; 12:289-96.
    • (1999) J Autoimmun , vol.12 , pp. 289-296
    • Schloot, N.C.1    Batstra, M.C.2    Duinkerken, G.3
  • 7
    • 10544223741 scopus 로고    scopus 로고
    • Naturally processed T cell epitopes from human glutamic acid decarboxylase identified using mice transgenic for the type 1 diabetes-associated human MHC class II allele, DRB1*0401
    • Wicker LS, Chen SL, Nepom GT et al. Naturally processed T cell epitopes from human glutamic acid decarboxylase identified using mice transgenic for the type 1 diabetes-associated human MHC class II allele, DRB1*0401. J Clin Invest 1996; 98:2597-603.
    • (1996) J Clin Invest , vol.98 , pp. 2597-2603
    • Wicker, L.S.1    Chen, S.L.2    Nepom, G.T.3
  • 8
    • 0030759825 scopus 로고    scopus 로고
    • Identification of immunodominant T cell epitopes of human glutamic acid decarboxylase 65 by using HLA-DR (alphal*0101,beta1*0401) transgenic mice
    • Patel SD, Cope AP, Cognia M et al. Identification of immunodominant T cell epitopes of human glutamic acid decarboxylase 65 by using HLA-DR (alphal*0101,beta1*0401) transgenic mice. Proc Natl Acad Sci USA 1997; 94:8082-7.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 8082-8087
    • Patel, S.D.1    Cope, A.P.2    Cognia, M.3
  • 9
    • 0033574642 scopus 로고    scopus 로고
    • High-resolution autoreactive epitope mapping and structural modeling of the 65 KDa form of human glutamic acid decarboxylase
    • Schwartz H, Chandonia JM, Kash S et al. High-resolution autoreactive epitope mapping and structural modeling of the 65 KDa form of human glutamic acid decarboxylase. J Mol Biol 1999; 287:983-99.
    • (1999) J Mol Biol , vol.287 , pp. 983-999
    • Schwartz, H.1    Chandonia, J.M.2    Kash, S.3
  • 10
    • 0034292407 scopus 로고    scopus 로고
    • Conformational epitopes on the diabetes autoantigen GAD65 identified by peptide phage display and molecular modeling
    • Myers MA, Davies JM, Tong JC et al. Conformational epitopes on the diabetes autoantigen GAD65 identified by peptide phage display and molecular modeling. J Immunol 2000; 165:3830-8.
    • (2000) J Immunol , vol.165 , pp. 3830-3838
    • Ma, M.1    Davies, J.M.2    Tong, J.C.3
  • 11
    • 0026673880 scopus 로고
    • Human monoclonal islet cell antibodies from a patient with insulin-dependent diabetes mellitus reveal glutamate decarboxylase as the target antigen
    • Richter W, Endl J, Eiermann TH et al. Human monoclonal islet cell antibodies from a patient with insulin-dependent diabetes mellitus reveal glutamate decarboxylase as the target antigen. Proc Natl Acad Sci USA 1992; 89:8467-71.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 8467-8471
    • Richter, W.1    Endl, J.2    Eiermann, T.H.3
  • 12
    • 0029931076 scopus 로고    scopus 로고
    • Four IgG anti-islet human monoclonal antibodies isolated from a type 1 diabetes patient recognize distinct epitopes of glutamic acid decarboxylase 65 and are somatically mutated
    • Madec AM, Rousset F, Ho S et al. Four IgG anti-islet human monoclonal antibodies isolated from a type 1 diabetes patient recognize distinct epitopes of glutamic acid decarboxylase 65 and are somatically mutated. J Immunol 1996; 156:3541-9.
    • (1996) J Immunol , vol.156 , pp. 3541-3549
    • Madec, A.M.1    Rousset, F.2    Ho, S.3
  • 13
    • 0030470633 scopus 로고    scopus 로고
    • Immune reactivity of diabetes-associated human monoclonal autoantibodies defines multiple epitopes and detects two domain boundaries in glutamate decarboxylase
    • Syren K, Lindsay L, Stoehrer B et al. Immune reactivity of diabetes-associated human monoclonal autoantibodies defines multiple epitopes and detects two domain boundaries in glutamate decarboxylase. J Immunol 1996; 157:5208-14.
    • (1996) J Immunol , vol.157 , pp. 5208-5214
    • Syren, K.1    Lindsay, L.2    Stoehrer, B.3
  • 14
    • 0030838447 scopus 로고    scopus 로고
    • Human B cells secreting immunoglobulin G to glutamic acid decarboxylase-65 from a non-diabetic patient with multiple autoantibodies and Graves' disease: A comparison with those present in Type I diabetes
    • Tremble J, Morgenthaler NG, Vlug A et al. Human B cells secreting immunoglobulin G to glutamic acid decarboxylase-65 from a non-diabetic patient with multiple autoantibodies and Graves' disease: a comparison with those present in Type I diabetes. J Clin Endocrinol Metab 1997; 82:2664-70.
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 2664-2670
    • Tremble, J.1    Morgenthaler, N.G.2    Vlug, A.3
  • 15
    • 1842475975 scopus 로고    scopus 로고
    • Epitope spreading and a variety but not disease specific GAD65 antibody response in type 1 diabetes
    • Sohnlein P, Muller M, Syren K et al. Epitope spreading and a variety but not disease specific GAD65 antibody response in type 1 diabetes. Diabetologia 2000; 43:210-7.
    • (2000) Diabetologia , vol.43 , pp. 210-217
    • Sohnlein, P.1    Muller, M.2    Syren, K.3
  • 16
    • 0032145276 scopus 로고    scopus 로고
    • B lymphocytes are crucial antigen-presenting cells in the pathogenic autoimmune response to GAD65 antigen in nonobese diabetic mice
    • Fallone M, Lee J, Patstone G, Yeung B, Sarvetnick N. B lymphocytes are crucial antigen-presenting cells in the pathogenic autoimmune response to GAD65 antigen in nonobese diabetic mice. J Immunol 1998; 161:1163-8.
    • (1998) J Immunol , vol.161 , pp. 1163-1168
    • Fallone, M.1    Lee, J.2    Patstone, G.3    Yeung, B.4    Sarvetnick, N.5
  • 17
    • 0032532294 scopus 로고    scopus 로고
    • B lymphocytes are critical antigen presenting cells for the initiation of T cell mediated autoimmune diabetes in nonobese diabetic mice
    • Serreze DV, Fleming SA, Chapman HD, Richard SD, Leiter EH, Tisch, RM. B lymphocytes are critical antigen presenting cells for the initiation of T cell mediated autoimmune diabetes in nonobese diabetic mice. J Immunol 1999; 151:3912-8.
    • (1999) J Immunol , vol.151 , pp. 3912-3918
    • Serreze, D.V.1    Fleming, S.A.2    Chapman, H.D.3    Richard, S.D.4    Leiter, E.H.5    Tisch, R.M.6
  • 18
    • 0033564970 scopus 로고    scopus 로고
    • I-Ag7-mediated antigen presentation by B lymphocytes is critical in overcoming a checkpoint in T cell tolerance to islet beta cells of nonobese diabetic mice
    • Noorchasm H, Lieu YK, Noorchasm N et al. I-Ag7-mediated antigen presentation by B lymphocytes is critical in overcoming a checkpoint in T cell tolerance to islet beta cells of nonobese diabetic mice. J Immunol 1999; 163:143-750.
    • (1999) J Immunol , vol.163 , pp. 143-750
    • Noorchasm, H.1    Lieu, Y.K.2    Noorchasm, N.3
  • 19
    • 0035889964 scopus 로고    scopus 로고
    • B cell specificity contributes to the outcome of diabetes in nonobese diabetic mice
    • Hulbert CB, Riseili M, Rojas M, Thomas JW. B cell specificity contributes to the outcome of diabetes in nonobese diabetic mice. J Immunol 2001; 167:5535-8.
    • (2001) J Immunol , vol.167 , pp. 5535-5538
    • Hulbert, C.B.1    Riseili, M.2    Rojas, M.3    Thomas, J.W.4
  • 20
    • 0035807589 scopus 로고    scopus 로고
    • Development of type 1 diabetes despite severe hereditary B cell deficiency
    • Martin S, Wolf-Eichbaum D, Duikerken G et al. Development of type 1 diabetes despite severe hereditary B cell deficiency. New Engl J Med 2001; 345:1036-40.
    • (2001) New Engl J Med , vol.345 , pp. 1036-1040
    • Martin, S.1    Wolf-Eichbaum, D.2    Duikerken, G.3
  • 21
    • 0029006389 scopus 로고
    • How can cryptic epitopes trigger autoimmunity
    • Lanzavecchia A. How can cryptic epitopes trigger autoimmunity. J Exp Med 1995; 181:1945-8.
    • (1995) J Exp Med , vol.181 , pp. 1945-1948
    • Lanzavecchia, A.1
  • 22
    • 0032005383 scopus 로고    scopus 로고
    • Role of B cell and Fc receptors in the selection of T cell epitopes
    • Amigorena S, Bonnerot C. Role of B cell and Fc receptors in the selection of T cell epitopes. Curr Opin Immunol 1998; 10:88-92.
    • (1998) Curr Opin Immunol , vol.10 , pp. 88-92
    • Amigorena, S.1    Bonnerot, C.2
  • 23
    • 0029035307 scopus 로고
    • Modulation of antigen processing by bound antibodies can boost or suppress class II major histocompatibility complex presentation of different T cell determinants
    • Simitsek PD, Campbell DG, Lanzavecchia A, Fairweather N, Watts C. Modulation of antigen processing by bound antibodies can boost or suppress class II major histocompatibility complex presentation of different T cell determinants. J Exp Med 1995; 181:1957-63.
    • (1995) J Exp Med , vol.181 , pp. 1957-1963
    • Simitsek, P.D.1    Campbell, D.G.2    Lanzavecchia, A.3    Fairweather, N.4    Watts, C.5
  • 24
    • 17344370078 scopus 로고    scopus 로고
    • Modulation by epitope specific antibodies of class II MHC restricted presentation of the tetanus toxin antigen
    • Watts C, Antoniou A, Manoury B et al. Modulation by epitope specific antibodies of class II MHC restricted presentation of the tetanus toxin antigen. Immunol Rev 1998; 164:11-6.
    • (1998) Immunol Rev , vol.164 , pp. 11-16
    • Watts, C.1    Antoniou, A.2    Manoury, B.3
  • 25
    • 0036467491 scopus 로고    scopus 로고
    • HLA-DM, HLA-DO and tapasin: Functional similarities and differences
    • Brocke P, Garbi N, Momburg F, Hammerling GJ. HLA-DM, HLA-DO and tapasin: functional similarities and differences. Curr Opin Immunol 2002; 14:22-9.
    • (2002) Curr Opin Immunol , vol.14 , pp. 22-29
    • Brocke, P.1    Garbi, N.2    Momburg, F.3    Hammerling, G.J.4
  • 26
    • 0033815194 scopus 로고    scopus 로고
    • GAD65-specific autoantibodies enhance the presentation of an immunodominant T cell epitope from GAD65
    • Reijonen H, Daniels TL, Lernmark Ä, Nepom GT. GAD65-specific autoantibodies enhance the presentation of an immunodominant T cell epitope from GAD65. Diabetes 2000; 49:1621-6.
    • (2000) Diabetes , vol.49 , pp. 1621-1626
    • Reijonen, H.1    Daniels, T.L.2    Lernmark, Ä.3    Nepom, G.T.4
  • 27
    • 0037100387 scopus 로고    scopus 로고
    • Suppressive effect of glutamic acid decarboxylase 65-specific autoimmune B lymphocytes on processing of T cell determinants located within the antibody epitope
    • Jaume JC, Parry SL, Madec AM, Sonderstrup G, Baekkeskov S. Suppressive effect of glutamic acid decarboxylase 65-specific autoimmune B lymphocytes on processing of T cell determinants located within the antibody epitope. J Immunol 2002; 169:665-72.
    • (2002) J Immunol , vol.169 , pp. 665-672
    • Jaume, J.C.1    Parry, S.L.2    Madec, A.M.3    Sonderstrup, G.4    Baekkeskov, S.5
  • 28
    • 0032880017 scopus 로고    scopus 로고
    • Autoreactive T cell responses in insulin dependent (type 1) diabetes mellitus. Report of the First International Workshop for Standardization of T cell Assays
    • Roep BO, Atkinson MA, van Endert PM et al. Autoreactive T cell responses in insulin dependent (type 1) diabetes mellitus. Report of the First International Workshop for Standardization of T cell Assays. J Autoimmun 1999; 13:267-82.
    • (1999) J Autoimmun , vol.13 , pp. 267-282
    • Roep, B.O.1    Atkinson, M.A.2    Van Endert, P.M.3
  • 29
    • 0021956416 scopus 로고
    • Antigen-specific interaction between T and B cells
    • Lanzavecchia A. Antigen-specific interaction between T and B cells. Nature 1985; 314:537-9.
    • (1985) Nature , vol.314 , pp. 537-539
    • Lanzavecchia, A.1
  • 30
    • 0021964141 scopus 로고
    • Measurements of the true affinity constant solution of antigen-antibody complexes by enzyme linked immunosorbent assay
    • Bertrand F, Chafforte AF, Djavadi-Ohaniance L, Goldberg ME. Measurements of the true affinity constant solution of antigen-antibody complexes by enzyme linked immunosorbent assay. J Immunol Meth 1984; 77:305-19.
    • (1984) J Immunol Meth , vol.77 , pp. 305-319
    • Bertrand, F.1    Chafforte, A.F.2    Djavadi-Ohaniance, L.3    Goldberg, M.E.4
  • 31
    • 0033179486 scopus 로고    scopus 로고
    • Differential presentation of glutamic acid decarboxylase 65 (GAD 65) T cell epitopes among HLA-DRB1*0401 positive individuals
    • Reijonen H, Elliot JF, van Endert PM, Nepom GT. Differential presentation of glutamic acid decarboxylase 65 (GAD 65) T cell epitopes among HLA-DRB1*0401 positive individuals. J Immunol 1999; 163:1674-81.
    • (1999) J Immunol , vol.163 , pp. 1674-1681
    • Reijonen, H.1    Elliot, J.F.2    Van Endert, P.M.3    Nepom, G.T.4
  • 32
    • 0037089576 scopus 로고    scopus 로고
    • Regulated expression of human histocompatibility leukocyte antigen (HLA)-DO during antigen-dependent and antigen-independent phases of B cell development
    • Chen X, Laur O, Kambayashi T et al. Regulated expression of human histocompatibility leukocyte antigen (HLA)-DO during antigen-dependent and antigen-independent phases of B cell development. J Exp Med 2002; 195:1053-62.
    • (2002) J Exp Med , vol.195 , pp. 1053-1062
    • Chen, X.1    Laur, O.2    Kambayashi, T.3
  • 33
    • 17444451528 scopus 로고    scopus 로고
    • Functional HLA-DM on the surface of B cells and immature dendritic cells
    • Arndt SO, Vogt AB, Markovic-Plese S et al. Functional HLA-DM on the surface of B cells and immature dendritic cells. EMBO J 2000; 19:1241-51.
    • (2000) EMBO J , vol.19 , pp. 1241-1251
    • Arndt, S.O.1    Vogt, A.B.2    Markovic-Plese, S.3
  • 34
    • 0026434554 scopus 로고
    • Separation of IL-4 production from proliferation by an altered T cell receptor ligand
    • Evavold BD, Allen PM. Separation of IL-4 production from proliferation by an altered T cell receptor ligand. Science 1991; 252:1308-10.
    • (1991) Science , vol.252 , pp. 1308-1310
    • Evavold, B.D.1    Allen, P.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.