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Volumn 15, Issue 4, 2003, Pages 405-420

Nonsmall-cell lung cancer: Chemoprevention studies

Author keywords

Chemoprevention; Lung cancer; Smoking cessation

Indexed keywords

ACETYLCYSTEINE; ALPHA INTERFERON; ALPHA TOCOPHEROL; ANETHOLE TRITHIONE; AROTINOID; BENZYL ISOTHIOCYANATE; BETA CAROTENE; BEXAROTENE; BIOLOGICAL MARKER; EPIDERMAL GROWTH FACTOR RECEPTOR; ERLOTINIB; ETRETINATE; FENRETINIDE; GEFITINIB; ISOTHIOCYANIC ACID DERIVATIVE; ISOTRETINOIN; NONSTEROID ANTIINFLAMMATORY AGENT; PHENETHYL ISOTHIOCYANATE; PROSTAGLANDIN SYNTHASE INHIBITOR; PROTEIN P53; PROTEIN TYROSINE KINASE INHIBITOR; RAS PROTEIN; RETINAL; RETINOIC ACID DERIVATIVE; RETINOID DERIVATIVE; RETINOL; SELENIUM; SELENOMETHIONINE; TAZAROTENE; UNINDEXED DRUG;

EID: 0347766081     PISSN: 10430679     EISSN: None     Source Type: Journal    
DOI: 10.1053/S1043-0679(03)00100-X     Document Type: Review
Times cited : (5)

References (152)
  • 2
    • 0347235485 scopus 로고    scopus 로고
    • President's message to teenage smokers
    • August
    • President's message to teenage smokers. Boston Herald August: 221:1, 1996
    • (1996) Boston Herald , vol.221 , pp. 1
  • 3
    • 0000068371 scopus 로고
    • Lung cancer diagnosis is being made with increasing frequency in former cigarette smokers!
    • Strauss G, DeCamp M, Dibiccaro E, et al: Lung cancer diagnosis is being made with increasing frequency in former cigarette smokers! Proc Am Soc Clin Oncol 14: 362, 1995
    • (1995) Proc. Am. Soc. Clin. Oncol. , vol.14 , pp. 362
    • Strauss, G.1    DeCamp, M.2    Dibiccaro, E.3
  • 4
    • 85030929539 scopus 로고    scopus 로고
    • Major Professional Organizations join Forces in light against tobacco addiction
    • Reuters Health Information News Service June 25
    • Major Professional Organizations join Forces in light against tobacco addiction. Reuters Health Information News Service June 25, 1996
    • (1996)
  • 5
    • 0024268967 scopus 로고
    • Smoking and lung cancer in women: Findings in a prospective study
    • Garfinkel L, Stellman SD: Smoking and lung cancer in women: Findings in a prospective study. Cancer Res 48:6951-6955, 1988
    • (1988) Cancer Res. , vol.48 , pp. 6951-6955
    • Garfinkel, L.1    Stellman, S.D.2
  • 6
    • 0345974434 scopus 로고
    • Long term survival following induction chemotherapy for Squamous cell carcinoma of the head and neck: A ten year follow-up
    • Salmon SE (ed): Orlando, FL, Grune & Stratton
    • Karp DD, Vaughan CW, Willet B, et al: Long term survival following induction chemotherapy for Squamous cell carcinoma of the head and neck: A ten year follow-up, in Salmon SE (ed): Adjuvant Therapy of Cancer V. Orlando, FL, Grune & Stratton, 1987, pp 119-128
    • (1987) Adjuvant Therapy of Cancer V , pp. 119-128
    • Karp, D.D.1    Vaughan, C.W.2    Willet, B.3
  • 7
    • 0023831071 scopus 로고
    • Projections of lung cancer mortality in the United States, 1985-2025
    • Brown CC, Kessler LG: Projections of lung cancer mortality in the United States, 1985-2025. J Natl Cancer Inst 80:43-51, 1988
    • (1988) J. Natl. Cancer Inst. , vol.80 , pp. 43-51
    • Brown, C.C.1    Kessler, L.G.2
  • 8
    • 0345974441 scopus 로고    scopus 로고
    • Lung cancer death rates in Boston from 1994-1996
    • November
    • Lung cancer death rates in Boston from 1994-1996. Boston Globe November. 255:1, 1998
    • (1998) Boston Globe , vol.255 , pp. 1
  • 9
    • 0012171426 scopus 로고
    • Early lung cancer cooperative study group: Early lung cancer detection-Summary and conclusion
    • (abstr)
    • Bailar JC: Early lung cancer cooperative study group: Early lung cancer detection-Summary and conclusion. Am Rev Respir Dis 130:565(abstr), 1984
    • (1984) Am. Rev. Respir. Dis. , vol.130 , pp. 565
    • Bailar, J.C.1
  • 10
    • 0024409066 scopus 로고
    • Considerations in the development of lung cancer screening tools
    • Mulshine JL, Tockman MS, Smart C: Considerations in the development of lung cancer screening tools. J Natl Cancer Inst 81:900-906, 1989
    • (1989) J. Natl. Cancer Inst. , vol.81 , pp. 900-906
    • Mulshine, J.L.1    Tockman, M.S.2    Smart, C.3
  • 11
    • 0026098703 scopus 로고
    • Screening for lung cancer: A critique of the Mayo Lung Project
    • Fontant RS, Sanderson DR, Woolner LB, et al: Screening for lung cancer: A critique of the Mayo Lung Project. Cancer 67(suppl 4):1155-1164, 1991
    • (1991) Cancer , vol.67 , Issue.SUPPL. 4 , pp. 1155-1164
    • Fontant, R.S.1    Sanderson, D.R.2    Woolner, L.B.3
  • 12
    • 0030899751 scopus 로고    scopus 로고
    • Screening for lung cancer: Another look, a different view
    • Strauss GM, Gleason RE, Sugarbaker DJ: Screening for lung cancer: Another look, a different view. Chest 111: 754-768, 1997
    • (1997) Chest , vol.111 , pp. 754-768
    • Strauss, G.M.1    Gleason, R.E.2    Sugarbaker, D.J.3
  • 13
    • 0347865921 scopus 로고    scopus 로고
    • Early diagnosis of lung cancer
    • Lam S, Shibuya H: Early diagnosis of lung cancer. Clin Chest Med 354:99-105, 1999
    • (1999) Clin. Chest Med. , vol.354 , pp. 99-105
    • Lam, S.1    Shibuya, H.2
  • 14
    • 0021733708 scopus 로고
    • Early lung cancer detection: Results of the initial (prevalence) radiologic and cytologic screening in the Memorial-Sloan Kettering study
    • Flehinger BH, Melamed MR, Zaman MB, et al: Early lung cancer detection: Results of the initial (prevalence) radiologic and cytologic screening in the Memorial-Sloan Kettering study. Am Rev Respir Dis 130:555-560, 1984
    • (1984) Am. Rev. Respir. Dis. , vol.130 , pp. 555-560
    • Flehinger, B.H.1    Melamed, M.R.2    Zaman, M.B.3
  • 16
    • 0021677409 scopus 로고
    • Early lung cancer detection: Results of the initial (prevalence) radiologic and cytologic screening in the Johns Hopkins study
    • Frost JK, Ball WC, Levin ML: Early lung cancer detection: Results of the initial (prevalence) radiologic and cytologic screening in the Johns Hopkins study. Am Rev Respir Dis 13:549-554, 1984
    • (1984) Am. Rev. Respir. Dis. , vol.13 , pp. 549-554
    • Frost, J.K.1    Ball, W.C.2    Levin, M.L.3
  • 17
    • 0030137543 scopus 로고    scopus 로고
    • Detection of early cancer by lung cancer screening
    • Saito Y, Takahashi S, Usada K, et al: Detection of early cancer by lung cancer screening. Nippon Rinsho 54: 1410-1414, 1996
    • (1996) Nippon Rinsho , vol.54 , pp. 1410-1414
    • Saito, Y.1    Takahashi, S.2    Usada, K.3
  • 18
    • 0031427367 scopus 로고    scopus 로고
    • Prospective detection of preclinical lung cancer: Results from two studies of heterogeneous nuclear ribonucleoprotein A2/B1 over-expression
    • Tockman MS, Mulshine JL, Piantadosi S, et al: Prospective detection of preclinical lung cancer: Results from two studies of heterogeneous nuclear ribonucleoprotein A2/B1 over-expression. Clin Cancer Res 3:2237-2246, 1997
    • (1997) Clin. Cancer Res. , vol.3 , pp. 2237-2246
    • Tockman, M.S.1    Mulshine, J.L.2    Piantadosi, S.3
  • 19
    • 16944362335 scopus 로고    scopus 로고
    • Purification and characterization of a protein that permits early detection of lung cancer: Identification of a heterogeneous nuclear ribonucleoprotein-A2/B1 as the antigen for monoclonal antibody 703D4
    • Zhou J, Mulshine JL, Unsworth EJ, et al: Purification and characterization of a protein that permits early detection of lung cancer: Identification of a heterogeneous nuclear ribonucleoprotein-A2/B1 as the antigen for monoclonal antibody 703D4. J Biol Chem 271:10760-10766, 1996
    • (1996) J. Biol. Chem. , vol.271 , pp. 10760-10766
    • Zhou, J.1    Mulshine, J.L.2    Unsworth, E.J.3
  • 20
    • 0024273335 scopus 로고
    • Sensitive and specific monoclonal antibody recognition of human lung cancer antigen on preserved sputum cells: A new approach to early lung cancer defection
    • Tockman MS, Gupta PK, Myers JD, et al: Sensitive and specific monoclonal antibody recognition of human lung cancer antigen on preserved sputum cells: A new approach to early lung cancer defection. J Clin Oncol 6:1685-1693, 1988
    • (1988) J. Clin. Oncol. , vol.6 , pp. 1685-1693
    • Tockman, M.S.1    Gupta, P.K.2    Myers, J.D.3
  • 21
    • 0033396697 scopus 로고    scopus 로고
    • Heterogeneous nuclear ribonucleoprotein A2/B1 upregulation in bronchial lavage specimens: A clinical marker of early lung cancer detection
    • Fielding P, Turnbull L, Prime W, et al: Heterogeneous nuclear ribonucleoprotein A2/B1 upregulation in bronchial lavage specimens: A clinical marker of early lung cancer detection. Clin Cancer Res 5:4048-4052, 1999
    • (1999) Clin. Cancer Res. , vol.5 , pp. 4048-4052
    • Fielding, P.1    Turnbull, L.2    Prime, W.3
  • 22
    • 11944271246 scopus 로고
    • p53 and chromosome 3 abnormalities, characteristic of malignant lung tumors, are detectable in pre-invasive lesions of the bronchus
    • Sundaresan V, Ganly P, Haselton P, et al: p53 and chromosome 3 abnormalities, characteristic of malignant lung tumors, are detectable in pre-invasive lesions of the bronchus. Oncogene 7:1989-1997, 1992
    • (1992) Oncogene , vol.7 , pp. 1989-1997
    • Sundaresan, V.1    Ganly, P.2    Haselton, P.3
  • 23
    • 0029082427 scopus 로고
    • Allele-specific loss in chromosome 9p loci in preneoplastic lesions accompanying non-small lung cancers
    • Kishimoto Y, Sugio K, Hung JY: Allele-specific loss in chromosome 9p loci in preneoplastic lesions accompanying non-small lung cancers. J Natl Cancer Inst 87:1224-1229, 1995
    • (1995) J. Natl. Cancer Inst. , vol.87 , pp. 1224-1229
    • Kishimoto, Y.1    Sugio, K.2    Hung, J.Y.3
  • 24
    • 0028138341 scopus 로고
    • Microsatellite alterations as clonal markers for the detection of human cancer
    • Mao L, Lee DJ, Tockman MS, et al: Microsatellite alterations as clonal markers for the detection of human cancer. Proc Natl Acad Sci U S A 91:9871-9875, 1994
    • (1994) Proc. Natl. Acad. Sci. U. S. A. , vol.91 , pp. 9871-9875
    • Mao, L.1    Lee, D.J.2    Tockman, M.S.3
  • 25
    • 0033590626 scopus 로고    scopus 로고
    • Sequential molecular abnormalities are involved in the multistage development of squamous cell lung carcinoma
    • Wistuba II, Behrens C, Milchgrub S: Sequential molecular abnormalities are involved in the multistage development of squamous cell lung carcinoma. Oncogene 18:643-650, 1999
    • (1999) Oncogene , vol.18 , pp. 643-650
    • Wistuba, I.I.1    Behrens, C.2    Milchgrub, S.3
  • 26
    • 1842298166 scopus 로고    scopus 로고
    • Clorial genetic alterations in the lungs of current and former smokers
    • Mao L, Lee JS, Kurie JM: Clorial genetic alterations in the lungs of current and former smokers. J Natl Cancer Inst 89:857-862, 1997
    • (1997) J. Natl. Cancer Inst. , vol.89 , pp. 857-862
    • Mao, L.1    Lee, J.S.2    Kurie, J.M.3
  • 28
    • 0031201298 scopus 로고    scopus 로고
    • Sputum screening by quantitative microscopy: Reexamination of a portion of the National Cancer Institute cooperative early lung cancer study
    • Payne PW, Sebo TJ, Doudkine A, et al: Sputum screening by quantitative microscopy: Reexamination of a portion of the National Cancer Institute cooperative early lung cancer study. Mayo Clin Proc 72:697-704, 1997
    • (1997) Mayo Clin. Proc. , vol.72 , pp. 697-704
    • Payne, P.W.1    Sebo, T.J.2    Doudkine, A.3
  • 29
    • 6844252883 scopus 로고    scopus 로고
    • Localization of bronchial intraepithelial neoplastic lesions by fluorescence bronchoscopy
    • Lam S, Kennedy T, Unger M, et al: Localization of bronchial intraepithelial neoplastic lesions by fluorescence bronchoscopy. Chest 113:696-702, 1998
    • (1998) Chest , vol.113 , pp. 696-702
    • Lam, S.1    Kennedy, T.2    Unger, M.3
  • 30
    • 0032719493 scopus 로고    scopus 로고
    • Advances in bronchoscopic procedures
    • Udaya B, Prakash S: Advances in bronchoscopic procedures. Chest 116:1403-1408, 1999
    • (1999) Chest , vol.116 , pp. 1403-1408
    • Udaya, B.1    Prakash, S.2
  • 31
    • 0033542870 scopus 로고    scopus 로고
    • Early Lung Cancer Action Project: Overall design and findings from baseline screening
    • Henschke CI, McCauley DI, Yankelevitz, et al: Early Lung Cancer Action Project: Overall design and findings from baseline screening. Lancet 354:99-105, 1999
    • (1999) Lancet , vol.354 , pp. 99-105
    • Henschke, C.I.1    McCauley, D.I.2    Yankelevitz, A.3
  • 32
    • 0025091456 scopus 로고
    • Prevention of second primary tumors with isotretinoin in squamous-cell carcinoma of the head and neck
    • Hong WK, Lippman SM, Itri LM, et al: Prevention of second primary tumors with isotretinoin in squamous-cell carcinoma of the head and neck. N Engl J Med 323:795-801, 1990
    • (1990) N. Engl. J. Med. , vol.323 , pp. 795-801
    • Hong, W.K.1    Lippman, S.M.2    Itri, L.M.3
  • 33
    • 0242469530 scopus 로고
    • The multiplicity of origin of malignant tumors: Collective review
    • Slaughter DP: The multiplicity of origin of malignant tumors: Collective review. Internat Abstr Surg 79:89-98, 1944
    • (1944) Internat. Abstr. Surg. , vol.79 , pp. 89-98
    • Slaughter, D.P.1
  • 34
    • 0001078174 scopus 로고
    • Multicentric origin of intraoral carcinoma
    • Slaughter DP: Multicentric origin of intraoral carcinoma. Surgery 20:133-146, 1946
    • (1946) Surgery , vol.20 , pp. 133-146
    • Slaughter, D.P.1
  • 35
    • 78651056338 scopus 로고
    • "Field cancerization" in oral stratified squamous epithelium. Clinical implications of multicentric origin
    • Slaughter DP, Southwick HW, Smejkal W: "Field cancerization" in oral stratified squamous epithelium. Clinical implications of multicentric origin. Cancer 6:963-968, 1953
    • (1953) Cancer , vol.6 , pp. 963-968
    • Slaughter, D.P.1    Southwick, H.W.2    Smejkal, W.3
  • 36
    • 0002363369 scopus 로고
    • The anatomical approach to the study of smoking and bronchogenic carcinoma: A preliminary report of forty-one cases
    • Auerbach O, Patrick TG, Stout AP, et al: The anatomical approach to the study of smoking and bronchogenic carcinoma: A preliminary report of forty-one cases. Cancer 9:76-83, 1956
    • (1956) Cancer , vol.9 , pp. 76-83
    • Auerbach, O.1    Patrick, T.G.2    Stout, A.P.3
  • 37
    • 0017136711 scopus 로고
    • Prevention of chemical carcinogenesis by vitamin A and its synthetic analogs (retinoids)
    • Sporn MB, Dunlop NM, Newton DL, et al: Prevention of chemical carcinogenesis by vitamin A and its synthetic analogs (retinoids). Fed Proc 35:1332-1338, 1976
    • (1976) Fed. Proc. , vol.35 , pp. 1332-1338
    • Sporn, M.B.1    Dunlop, N.M.2    Newton, D.L.3
  • 38
    • 0023748414 scopus 로고
    • Genetic alterations during colorectal tumor development
    • Vogelstein B, Fearon ER, Hamilton SR, et al: Genetic alterations during colorectal tumor development. N Engl J Med. 319:525-535, 1988
    • (1988) N. Engl. J. Med. , vol.319 , pp. 525-535
    • Vogelstein, B.1    Fearon, E.R.2    Hamilton, S.R.3
  • 40
    • 0027166695 scopus 로고
    • K-ras oncegene activation in lung adenocarcinomas from former smokers: Evidence that K-ras mutations are an early and irreversible event in the development of adenocarcinoma of the lung
    • Westra WH, Slebos RJ, Offerhaus GJ, et al: K-ras oncegene activation in lung adenocarcinomas from former smokers: Evidence that K-ras mutations are an early and irreversible event in the development of adenocarcinoma of the lung. Cancer 72:432-438, 1993
    • (1993) Cancer , vol.72 , pp. 432-438
    • Westra, W.H.1    Slebos, R.J.2    Offerhaus, G.J.3
  • 41
    • 0002466673 scopus 로고    scopus 로고
    • The role of MYC, JUN, and FOS Oncogenes
    • Pass HI, Mitchell JB, Johnson DH, et al (eds): Philadelphia, PA, Lippincott-Raven
    • Johnson BE: The role of MYC, JUN, and FOS Oncogenes, in Pass HI, Mitchell JB, Johnson DH, et al (eds): Human Lung Cancer. Lung Cancer: Principles and Practice. Philadelphia, PA, Lippincott-Raven, 1996, pp 83-98
    • (1996) Human Lung Cancer. Lung Cancer: Principles and Practice , pp. 83-98
    • Johnson, B.E.1
  • 42
    • 0026678007 scopus 로고
    • Quantitation of biological markers (p53, c-myc, Ki-67, and DNA ploidy) by multiparameter flow cytometry in non-small cell lung cancer
    • Morkve O, Halvorsen OJ, Stangeland L, et al: Quantitation of biological markers (p53, c-myc, Ki-67, and DNA ploidy) by multiparameter flow cytometry in non-small cell lung cancer. Int J Cancer 52:851-855, 1992
    • (1992) Int. J. Cancer , vol.52 , pp. 851-855
    • Morkve, O.1    Halvorsen, O.J.2    Stangeland, L.3
  • 43
    • 0025126386 scopus 로고
    • Jun: Oncogenes and transcription factors
    • Vogt PK, Bos TJ: Jun: Oncogenes and transcription factors. Adv Cancer Res 55:1-35, 1990
    • (1990) Adv. Cancer Res. , vol.55 , pp. 1-35
    • Vogt, P.K.1    Bos, T.J.2
  • 44
    • 0025720735 scopus 로고
    • The role of Jun, Fos, and the AP-1 complex in cell proliferation and transformation
    • 1072
    • Angel P, Karin M: The role of Jun, Fos, and the AP-1 complex in cell proliferation and transformation. Biochem Biophys Arta 1072:129-157, 1991
    • (1991) Biochem. Biophys. Acta , pp. 129-157
    • Angel, P.1    Karin, M.2
  • 45
    • 0024999129 scopus 로고
    • Protooncogene c-fos as a transcription factor
    • Distel RJ, Spiegelman BM: Protooncogene c-fos as a transcription factor. Adv Cancer Res 55:37-55, 1990
    • (1990) Adv. Cancer Res. , vol.55 , pp. 37-55
    • Distel, R.J.1    Spiegelman, B.M.2
  • 46
    • 0029008108 scopus 로고
    • Retinoid chemoprevention of aerodigestive cancer: From basic research to the clinic
    • Hong WK, Lippman SM, Hittelman WN, et al: Retinoid chemoprevention of aerodigestive cancer: From basic research to the clinic. Clin Cancer Res 1:677-686, 1995
    • (1995) Clin. Cancer Res. , vol.1 , pp. 677-686
    • Hong, W.K.1    Lippman, S.M.2    Hittelman, W.N.3
  • 47
    • 0028071555 scopus 로고
    • Mutations in the p53 tumor suppressor gene: Clues to cancer etiology and molecular pathogenesis
    • Greenblatt MS, Bennett WP, Hollstein M, et al: Mutations in the p53 tumor suppressor gene,: Clues to cancer etiology and molecular pathogenesis. Cancer Res 54: 4855-4878, 1994
    • (1994) Cancer Res. , vol.54 , pp. 4855-4878
    • Greenblatt, M.S.1    Bennett, W.P.2    Hollstein, M.3
  • 48
    • 0028331587 scopus 로고
    • Farnesyltransferase inhibitors: Ras rescarch yields a potential cancer therapeutic
    • Gibbs JB, Oliff A Kohl NE: Farnesyltransferase inhibitors: ras rescarch yields a potential cancer therapeutic. Cell 77:175-178, 1994
    • (1994) Cell , vol.77 , pp. 175-178
    • Gibbs, J.B.1    Oliff, A.2    Kohl, N.E.3
  • 49
    • 0028183001 scopus 로고
    • Declining FEV1 and chronic productive cough in cigarette smokers: A 25-year prospective study of lung cancer incidence in Tecumseh, Michigan
    • Islam SS, Schottenfeld D: Declining FEV1 and chronic productive cough in cigarette smokers: A 25-year prospective study of lung cancer incidence in Tecumseh, Michigan. Cancer Epidemiol Biomarkers Prev 3:289-298, 1994
    • (1994) Cancer Epidemiol. Biomarkers Prev. , vol.3 , pp. 289-298
    • Islam, S.S.1    Schottenfeld, D.2
  • 50
    • 0000243292 scopus 로고    scopus 로고
    • Epidemiology of lung cancer
    • Pass HI, Mitchell JB, Johnson DH, et al (eds): Philadelphia, PA, Lippincott-Raven Publishers
    • Schottenfeld D: Epidemiology of lung cancer, in Pass HI, Mitchell JB, Johnson DH, et al (eds): Lung Cancer: Principles and Practice. Philadelphia, PA, Lippincott-Raven Publishers, 1996, pp 305-321
    • (1996) Lung Cancer: Principles and Practice , pp. 305-321
    • Schottenfeld, D.1
  • 51
    • 0021879645 scopus 로고
    • Hereditary cancer, oncogenes, and anti-oncogenes
    • Knudson AG: Hereditary cancer, oncogenes, and anti-oncogenes. Cancer Res 45:1437-1443, 1985
    • (1985) Cancer Res. , vol.45 , pp. 1437-1443
    • Knudson, A.G.1
  • 53
    • 0027214689 scopus 로고
    • An association between the risk of cancer and mutations in the HRAS1 minisatellite locus
    • Krontiris TG, Devlin B, Karp DD, et al: An association between the risk of cancer and mutations in the HRAS1 minisatellite locus. N Engl J Med 329:517-523, 1993
    • (1993) N. Engl. J. Med. , vol.329 , pp. 517-523
    • Krontiris, T.G.1    Devlin, B.2    Karp, D.D.3
  • 54
    • 0025304032 scopus 로고
    • Debrisoquine oxidation phenotype and susceptibility to lung cancer
    • Speirs CJ, Murray S, Davies DS, et al: Debrisoquine oxidation phenotype and susceptibility to lung cancer. Br J Clin Pharmacol. 29:101-109, 1990
    • (1990) Br. J. Clin. Pharmacol. , vol.29 , pp. 101-109
    • Speirs, C.J.1    Murray, S.2    Davies, D.S.3
  • 56
    • 0030741819 scopus 로고    scopus 로고
    • Analysis of CYP2D6 expression in human lung: Implications for the association between CYP2D6 activity and susceptibility to lung cancer
    • Kivisto KT, Griese EU, Stuven T, et al: Analysis of CYP2D6 expression in human lung: Implications for the association between CYP2D6 activity and susceptibility to lung cancer. Pharmacogenetics 7:295-302, 1997
    • (1997) Pharmacogenetics , vol.7 , pp. 295-302
    • Kivisto, K.T.1    Griese, E.U.2    Stuven, T.3
  • 57
    • 0029021815 scopus 로고
    • Diagnosis of polymorphisms in carcinogen-activating and inactivating enzymes and cancer susceptibility - A review
    • Raunio H, Husgafvel-Pursiainen K, Anttila S, et al: Diagnosis of polymorphisms in carcinogen-activating and inactivating enzymes and cancer susceptibility-A review. Gene 159:113-121, 1995
    • (1995) Gene , vol.159 , pp. 113-121
    • Raunio, H.1    Husgafvel-Pursiainen, K.2    Anttila, S.3
  • 58
    • 0028967509 scopus 로고
    • Genetic factors in individual responses to environmental exposures
    • Hirvonen A: Genetic factors in individual responses to environmental exposures. Occup Environ Med 37:37-43, 1995
    • (1995) Occup. Environ. Med. , vol.37 , pp. 37-43
    • Hirvonen, A.1
  • 59
    • 0026323687 scopus 로고
    • Carcinogenesis and cancer - Different perspectives on the same disease
    • Sporn MB: Carcinogenesis and cancer-Different perspectives on the same disease. Cancer Res 51:6215-6218, 1991
    • (1991) Cancer Res. , vol.51 , pp. 6215-6218
    • Sporn, M.B.1
  • 62
    • 0027227595 scopus 로고
    • Differentiation therapy of cancer: Laboratory and clinical investigations
    • (Meeting Report)
    • Borden EC, Lotan R, Levens D, et al: Differentiation therapy of cancer: Laboratory and clinical investigations (Meeting Report). Cancer Res 53:4109-4115, 1993
    • (1993) Cancer Res. , vol.53 , pp. 4109-4115
    • Borden, E.C.1    Lotan, R.2    Levens, D.3
  • 63
    • 0346605770 scopus 로고
    • The regulation and gene expression by retinoids in normal and tumorigenic epithelial cells
    • Gudas L, Hu L: The regulation and gene expression by retinoids in normal and tumorigenic epithelial cells. Proc Annu Meet Am Assoc Cancer Res 34:588-589, 1993
    • (1993) Proc. Annu. Meet. Am. Assoc. Cancer Res. , vol.34 , pp. 588-589
    • Gudas, L.1    Hu, L.2
  • 64
    • 0027458758 scopus 로고
    • A retinoid responsive cytokine gene, MK is preferentially expressed in the proximal tubules of the kidney and human tumor cell lines
    • Kitamura M, Shirasawa T, Mitarai T, et al: A retinoid responsive cytokine gene, MK is preferentially expressed in the proximal tubules of the kidney and human tumor cell lines. Am J Pathol 142:425-431, 1993
    • (1993) Am. J. Pathol. , vol.142 , pp. 425-431
    • Kitamura, M.1    Shirasawa, T.2    Mitarai, T.3
  • 65
    • 0029609786 scopus 로고
    • Screening, early detection, and early intervention strategies for lung cancer. Cancer Control
    • Wagner H, Ruckdeschel JC: Screening, early detection, and early intervention strategies for lung cancer. Cancer Control. J Moffitt Cancer Center 6:493-502, 1995
    • (1995) J. Moffitt Cancer Center , vol.6 , pp. 493-502
    • Wagner, H.1    Ruckdeschel, J.C.2
  • 66
    • 0025937940 scopus 로고
    • High frequency of retinoic acid receptor beta abnormalities in human lung cancer
    • Gebert JF, Moghal N, Frangioni JV, et al: High frequency of retinoic acid receptor beta abnormalities in human lung cancer. Oncogene 6:1859-1868, 1991
    • (1991) Oncogene , vol.6 , pp. 1859-1868
    • Gebert, J.F.1    Moghal, N.2    Frangioni, J.V.3
  • 67
    • 0012538386 scopus 로고
    • Selective suppression of retinoic acid receptor b (RAR-b) expression in squamous metaplasia and in non-small cell lung cancers (NSCLC) compared to normal bronchial epithelium
    • Lotan R, Sozzi G, Ro J, et al: Selective suppression of retinoic acid receptor b (RAR-b) expression in squamous metaplasia and in non-small cell lung cancers (NSCLC) compared to normal bronchial epithelium. Proc Am Soc Clin Oncol 14:165, 1995
    • (1995) Proc. Am. Soc. Clin. Oncol. , vol.14 , pp. 165
    • Lotan, R.1    Sozzi, G.2    Ro, J.3
  • 68
    • 0029044431 scopus 로고
    • Suppression of retinoic acid receptor in premalignant oral lesions and its upregulation by isotretinoin
    • Lotan R, Xu XC, Lippman SM, et al: Suppression of retinoic acid receptor in premalignant oral lesions and its upregulation by isotretinoin. N Engl J Med 332:1405-1410, 1995
    • (1995) N. Engl. J. Med. , vol.332 , pp. 1405-1410
    • Lotan, R.1    Xu, X.C.2    Lippman, S.M.3
  • 70
    • 0345974432 scopus 로고    scopus 로고
    • Personal communication
    • Kurie JM: Personal communication, 2002
    • (2002)
    • Kurie, J.M.1
  • 71
    • 0037149018 scopus 로고    scopus 로고
    • Inhalation of aerosolized vitamin A: Reversibility of metaplasia and dysplasia of human respiratory epithelia - A prospective pilot study
    • Kohlhaufl M, Haussinger K, Stanzel F, et al: Inhalation of aerosolized vitamin A: Reversibility of metaplasia and dysplasia of human respiratory epithelia - A prospective pilot study. Eur J Med Res 7:72-78, 2002
    • (2002) Eur. J. Med. Res. , vol.7 , pp. 72-78
    • Kohlhaufl, M.1    Haussinger, K.2    Stanzel, F.3
  • 72
    • 0029154915 scopus 로고
    • N-Acetylcysteine (NAC) and glutathione (GSH): Antioxidant and chemopreventive properties, with special reference to lung cancer
    • van Zandwijk N: N-Acetylcysteine (NAC) and glutathione (GSH): Antioxidant and chemopreventive properties, with special reference to lung cancer. J Cell Biochem Suppl 22:24-32, 1995
    • (1995) J. Cell Biochem. Suppl. , vol.22 , pp. 24-32
    • van Zandwijk, N.1
  • 73
    • 3042744558 scopus 로고
    • Cellular injury by oxidants
    • Cochrane CG: Cellular injury by oxidants. Am J Med 91:23-30, 1991
    • (1991) Am. J. Med. , vol.91 , pp. 23-30
    • Cochrane, C.G.1
  • 74
    • 0000387829 scopus 로고
    • Clinical evaluation of a new mucolytic agent acetyl cysteine
    • Webb WR: Clinical evaluation of a new mucolytic agent acetyl cysteine. J Thorac Cardiovasc Surg 44:330-343, 1962
    • (1962) J. Thorac. Cardiovasc. Surg. , vol.44 , pp. 330-343
    • Webb, W.R.1
  • 76
    • 0020535852 scopus 로고
    • Clinical safety of high oral doses of acetylcysteine
    • Miller LF, Rumack BH: Clinical safety of high oral doses of acetylcysteine. Semin Oncol 10(suppl 1):76-85, 1983
    • (1983) Semin. Oncol. , vol.10 , Issue.SUPPL. 1 , pp. 76-85
    • Miller, L.F.1    Rumack, B.H.2
  • 77
    • 0029079686 scopus 로고
    • Chemopreventive properties and mechanisms of N-Acetylcysteine. The Experimental Background
    • De Flora S, Cesarone CF, Balansky RM, et al: Chemopreventive properties and mechanisms of N-Acetylcysteine. The Experimental Background. J Cell Biochem Suppl 22:33-41, 1995
    • (1995) J. Cell Biochem. Suppl. , vol.22 , pp. 33-41
    • De Flora, S.1    Cesarone, C.F.2    Balansky, R.M.3
  • 78
    • 0032512702 scopus 로고    scopus 로고
    • Chemopreventive potential of fumaric acid, N-acetylcysteine, N-(4-hydroxyphenyl) retinamide and á-carotene for tobacco-nitrosamine induced lung tumors in A/J mice
    • Conaway CC, Jiao D, Kelloff GJ, et al: Chemopreventive potential of fumaric acid, N-acetylcysteine, N-(4-hydroxyphenyl) retinamide and á-carotene for tobacco-nitrosamine induced lung tumors in A/J mice. Cancer Lett 124:85-93, 1998
    • (1998) Cancer Lett. , vol.124 , pp. 85-93
    • Conaway, C.C.1    Jiao, D.2    Kelloff, G.J.3
  • 79
    • 0027410807 scopus 로고
    • EUROSCAN: The European organization for research and treatment of cancer (EORTC): Chemoprevention study in lung cancer
    • van Zandwijk N, Pastorino U, de Vries N, et al: EUROSCAN: The European organization for research and treatment of cancer (EORTC): Chemoprevention study in lung cancer. Lung Cancer 9:351-356, 1993
    • (1993) Lung Cancer , vol.9 , pp. 351-356
    • van Zandwijk, N.1    Pastorino, U.2    de Vries, N.3
  • 80
    • 0022893548 scopus 로고
    • Serum beta carotene, vitamin A and E, and selenium and the risk of lung cancer
    • Menkes MS, Constock GW, Vuilleumier JP, et al: Serum beta carotene, vitamin A and E, and selenium and the risk of lung cancer. N Engl J Med 315:1250-1254, 1986
    • (1986) N. Engl. J. Med. , vol.315 , pp. 1250-1254
    • Menkes, M.S.1    Constock, G.W.2    Vuilleumier, J.P.3
  • 81
    • 0342786589 scopus 로고
    • Reduction in toxicity of high-dose 13-cis-retinoic acid (13-cRA) with a tocopherol (AT)
    • Dimery I, Shirinian M, Heyne K, et al: Reduction in toxicity of high-dose 13-cis-retinoic acid (13-cRA) with a tocopherol (AT). Proc Am Soc Clin Oncol 11:399, 1992
    • (1992) Proc. Am. Soc. Clin. Oncol. , vol.11 , pp. 399
    • Dimery, I.1    Shirinian, M.2    Heyne, K.3
  • 82
    • 85030934254 scopus 로고    scopus 로고
    • Modulation of biomarkers with biochemoprevention therapy in advanced premalignant lesions in the upper aerodigestive tract
    • Shin DM, Mao L, Papadimitrakopoulou V, et al: Modulation of biomarkers with biochemoprevention therapy in advanced premalignant lesions in the upper aerodigestive tract. Proc Annu Meet Soc Clin Oncol 16:A1557, 1997
    • (1997) Proc. Annu. Meet. Soc. Clin. Oncol. , vol.16
    • Shin, D.M.1    Mao, L.2    Papadimitrakopoulou, V.3
  • 83
    • 0014672401 scopus 로고
    • Possible protective effect of selenium against human cancer
    • Shamberger RJ, Frost DV: Possible protective effect of selenium against human cancer. Can Med Assoc J 100: 682, 1969
    • (1969) Can. Med. Assoc. J. , vol.100 , pp. 682
    • Shamberger, R.J.1    Frost, D.V.2
  • 84
    • 0027363891 scopus 로고
    • A prospective cohort study on selenium status and the risk of lung cancer
    • van den Brandt PA, Goldbohm RA, van't Veer P, et al: A prospective cohort study on selenium status and the risk of lung cancer. Cancer Res 53:4860-4865, 1993
    • (1993) Cancer Res. , vol.53 , pp. 4860-4865
    • van den Brandt, P.A.1    Goldbohm, R.A.2    van't Veer, P.3
  • 85
    • 1642625262 scopus 로고    scopus 로고
    • Effects of selenium supplementation for cancer prevention in patients with carcinoma of the skin. A randomized controlled trial
    • Nutritional Prevention of Cancer Study Group
    • Clark LC, Combs GF Jr, Turnbull BW, et al: Effects of selenium supplementation for cancer prevention in patients with carcinoma of the skin. A randomized controlled trial. Nutritional Prevention of Cancer Study Group. JAMA 276:1957-1963, 1996
    • (1996) JAMA , vol.276 , pp. 1957-1963
    • Clark, L.C.1    Combs Jr., G.F.2    Turnbull, B.W.3
  • 86
    • 0027275148 scopus 로고
    • Nutrition intervention trials in Linxian, China: Supplementation with specific vitamin/mineral combinations, cancer incidence, and disease-specific mortality in the general population
    • Blot WJ, Li JY, Taylor PR, et al: Nutrition intervention trials in Linxian, China: Supplementation with specific vitamin/mineral combinations, cancer incidence, and disease-specific mortality in the general population. J Natl Cancer Inst 85:1483-1492, 1993
    • (1993) J. Natl. Cancer Inst. , vol.85 , pp. 1483-1492
    • Blot, W.J.1    Li, J.Y.2    Taylor, P.R.3
  • 87
    • 0029837050 scopus 로고    scopus 로고
    • Chemoprevention of lung cancer by isothiocyanates
    • Hecht SS: Chemoprevention of lung cancer by isothiocyanates. Adv Exp Med Biol 401:1-11, 1996
    • (1996) Adv. Exp. Med. Biol. , vol.401 , pp. 1-11
    • Hecht, S.S.1
  • 88
    • 0023204238 scopus 로고
    • Mechanism of protection against aflatoxin tumorigenicity in rats fed 5-(2-pyrazinyl)-4-methyl-1, 2-dithiol-3-thione (oltipraz) and related 1, 2-dithiol-3-thiones and 1, 2-dithiol-3-ones
    • Kensler TW, Egner PA, Dolan PM, et al: Mechanism of protection against aflatoxin tumorigenicity in rats fed 5-(2-pyrazinyl)-4-methyl-1, 2-dithiol-3-thione (oltipraz) and related 1, 2-dithiol-3-thiones and 1, 2-dithiol-3-ones. Cancer Res 47:4271-4277, 1987
    • (1987) Cancer Res. , vol.47 , pp. 4271-4277
    • Kensler, T.W.1    Egner, P.A.2    Dolan, P.M.3
  • 89
    • 0027290648 scopus 로고
    • Chemoprevention of colon carcinogenesis by organosulfur compounds
    • Reddy BS, Rao CV, Rivenson A, et al: Chemoprevention of colon carcinogenesis by organosulfur compounds. Cancer Res 53:3493-3498, 1993
    • (1993) Cancer Res. , vol.53 , pp. 3493-3498
    • Reddy, B.S.1    Rao, C.V.2    Rivenson, A.3
  • 90
    • 0030980781 scopus 로고    scopus 로고
    • Overexpression of the epidermal growth factor receptor and its ligand transforming growth factor a is frequent in resectable non-small cell lung cancer but does not predict tumor progression
    • Rusch V, Klimstra D, Venkatraman E, et al: Overexpression of the epidermal growth factor receptor and its ligand transforming growth factor a is frequent in resectable non-small cell lung cancer but does not predict tumor progression. Clin Cancer Res 2:515-522, 1997
    • (1997) Clin. Cancer Res. , vol.2 , pp. 515-522
    • Rusch, V.1    Klimstra, D.2    Venkatraman, E.3
  • 91
    • 10244243723 scopus 로고    scopus 로고
    • Increased epidermal growth factor receptor expression in metaplastic bronchial epithelium
    • Kurie JM, Shin H, Lee J, et al: Increased epidermal growth factor receptor expression in metaplastic bronchial epithelium. Clin Cancer Res 2:1787-1793, 1996
    • (1996) Clin. Cancer Res. , vol.2 , pp. 1787-1793
    • Kurie, J.M.1    Shin, H.2    Lee, J.3
  • 92
    • 0025768216 scopus 로고
    • Epidermal growth factor receptor in lung malignancies: Comparison between cancer and normal tissue
    • Dittadi R, Gion M, Pagan V, et al: Epidermal growth factor receptor in lung malignancies: Comparison between cancer and normal tissue. Br J Cancer 64:741-744, 1991
    • (1991) Br. J. Cancer , vol.64 , pp. 741-744
    • Dittadi, R.1    Gion, M.2    Pagan, V.3
  • 93
    • 0030297662 scopus 로고    scopus 로고
    • A comparison of epidermal growth factor levels and other prognostic parameters in non-small cell lung cancer
    • Fujino S, Enokibori T, Tezuka N, et al: A comparison of epidermal growth factor levels and other prognostic parameters in non-small cell lung cancer. Eur J Cancer 32:2070-2074, 1996
    • (1996) Eur. J. Cancer , vol.32 , pp. 2070-2074
    • Fujino, S.1    Enokibori, T.2    Tezuka, N.3
  • 94
    • 0028913802 scopus 로고
    • Aberrant expression of p53 or the epidermal growth factor receptor is frequent in early bronchial neoplasia, and co-expression precedes squamous cell carcinoma development
    • Rusch V, Klimstra DS, Linkov I, et al: Aberrant expression of p53 or the epidermal growth factor receptor is frequent in early bronchial neoplasia, and co-expression precedes squamous cell carcinoma development. Cancer Res 55:1365-1372, 1995
    • (1995) Cancer Res. , vol.55 , pp. 1365-1372
    • Rusch, V.1    Klimstra, D.S.2    Linkov, I.3
  • 95
    • 0028955388 scopus 로고
    • Epidermal growth factor-related peptides and their receptors in human malignancies
    • Salomon D, Brandt R, Ciardiello F, et al: Epidermal growth factor-related peptides and their receptors in human malignancies. Crit Rev Oncol Hematol 19:183-232, 1995
    • (1995) Crit. Rev. Oncol. Hematol. , vol.19 , pp. 183-232
    • Salomon, D.1    Brandt, R.2    Ciardiello, F.3
  • 96
    • 0033257956 scopus 로고    scopus 로고
    • Dominance of ErbB-1 heterodimers in lung epithelial cells overexpressing ErbB-2
    • Fernandes A, Hamburger A, Gerwin B: Dominance of ErbB-1 heterodimers in lung epithelial cells overexpressing ErbB-2. Am J Respir Cell Mol Biol 21:701-709, 1999
    • (1999) Am. J. Respir. Cell Mol. Biol. , vol.21 , pp. 701-709
    • Fernandes, A.1    Hamburger, A.2    Gerwin, B.3
  • 97
    • 0030206987 scopus 로고    scopus 로고
    • The epidermal growth factor receptor and its ligands as therapeutic targets in human tumors
    • Rusch V, Mendelsohn J, Dmitrovsky E: The epidermal growth factor receptor and its ligands as therapeutic targets in human tumors. Cytokine Growth Factor Rev 7:133-141, 1996
    • (1996) Cytokine Growth Factor Rev. , vol.7 , pp. 133-141
    • Rusch, V.1    Mendelsohn, J.2    Dmitrovsky, E.3
  • 99
    • 0026095665 scopus 로고
    • A retroviral oncegene, akt, encoding a serine-threonine kinase containing an SH2-like region
    • Bellacosa A, Testa JR, Staal SP, et al: A retroviral oncegene, akt, encoding a serine-threonine kinase containing an SH2-like region. Science 254:274-277, 1991
    • (1991) Science , vol.254 , pp. 274-277
    • Bellacosa, A.1    Testa, J.R.2    Staal, S.P.3
  • 100
    • 0035008874 scopus 로고    scopus 로고
    • Activation of AKT (protein kinase B) in mammary epithelium provides a critical cell survival signal required for tumor progression
    • Hutchinson J, Jin J, Cardiff RD, et al: Activation of AKT (protein kinase B) in mammary epithelium provides a critical cell survival signal required for tumor progression. Mol Cell Biol. 21:2203-2212, 2001
    • (2001) Mol. Cell Biol. , vol.21 , pp. 2203-2212
    • Hutchinson, J.1    Jin, J.2    Cardiff, R.D.3
  • 101
    • 0031870959 scopus 로고    scopus 로고
    • PTEN is essential for embryonic development and tumor suppression
    • DiCristofano A, Pesce B, Cordon-Cardo C, et al: PTEN is essential for embryonic development and tumor suppression. Nat Genet 19:348-355, 1998
    • (1998) Nat. Genet. , vol.19 , pp. 348-355
    • DiCristofano, A.1    Pesce, B.2    Cordon-Cardo, C.3
  • 102
    • 0000440912 scopus 로고    scopus 로고
    • Transformation of chicken cells by the gene encoding the catalytic subunit of PI3-kinase
    • Chang HW, Aoki M, Fruman D, et al: Transformation of chicken cells by the gene encoding the catalytic subunit of PI3-kinase. Science 276:1848-1850, 1997
    • (1997) Science , vol.276 , pp. 1848-1850
    • Chang, H.W.1    Aoki, M.2    Fruman, D.3
  • 103
    • 85030918635 scopus 로고    scopus 로고
    • AstraZeneca Waltham, MA, AstraZeneca Pharmaceuticals LP
    • AstraZeneca: ZD1839 Investigator's Brochure. Waltham, MA, AstraZeneca Pharmaceuticals LP, 2001
    • (2001) ZD1839 Investigator's Brochure
  • 104
    • 0030774045 scopus 로고    scopus 로고
    • Induction of apoptosis and cell cycle arrest by CP-358, 774, an inhibitor of epidermal growth factor receptor tyrosine kinase
    • Moyer JD, Barbacci EG, Iwata KK, et al: Induction of apoptosis and cell cycle arrest by CP-358, 774, an inhibitor of epidermal growth factor receptor tyrosine kinase. Cancer Res 57:4838-4848, 1997
    • (1997) Cancer Res. , vol.57 , pp. 4838-4848
    • Moyer, J.D.1    Barbacci, E.G.2    Iwata, K.K.3
  • 105
    • 0027457670 scopus 로고
    • The human EGF receptor as a target for cancer therapy: Six new rat mAbs against the receptor on the breast carcinoma MDA-MB 468
    • Modjtahedi H, Styles JM, Dean CJ: The human EGF receptor as a target for cancer therapy: Six new rat mAbs against the receptor on the breast carcinoma MDA-MB 468. Br J Cancer 67:247-253, 1993
    • (1993) Br. J. Cancer , vol.67 , pp. 247-253
    • Modjtahedi, H.1    Styles, J.M.2    Dean, C.J.3
  • 106
    • 0027339486 scopus 로고
    • Immunotherapy of human tumour xenografts overexpressing the EGF receptor with rat antibodies that block growth factor-receptor interaction
    • Modjtahedi H, Eccles S, Box G, et al: Immunotherapy of human tumour xenografts overexpressing the EGF receptor with rat antibodies that block growth factor-receptor interaction. Br J Cancer 67:254-261, 1993
    • (1993) Br. J. Cancer , vol.67 , pp. 254-261
    • Modjtahedi, H.1    Eccles, S.2    Box, G.3
  • 107
    • 0027538862 scopus 로고
    • Antitumor activity of combinations of antibodies directed against different epitopes on the extracellular domain of the human EGF receptor
    • Modjtahedi H, Eccles SA, Box G, et al: Antitumor activity of combinations of antibodies directed against different epitopes on the extracellular domain of the human EGF receptor. Cell Biophys 22:129-146, 1993
    • (1993) Cell Biophys. , vol.22 , pp. 129-146
    • Modjtahedi, H.1    Eccles, S.A.2    Box, G.3
  • 108
    • 0019499955 scopus 로고
    • Ten human carcinoma cell lines derived from squamous carcinomas of the head and neck
    • Easty DM, Easty GC, Carter RL, et al: Ten human carcinoma cell lines derived from squamous carcinomas of the head and neck. Br J Cancer 43:772-785, 1981
    • (1981) Br. J. Cancer , vol.43 , pp. 772-785
    • Easty, D.M.1    Easty, G.C.2    Carter, R.L.3
  • 109
    • 85030924262 scopus 로고    scopus 로고
    • Genentech, Inc San Francisco, CA, Genentech, Inc
    • Genentech, Inc: Investigator's Brochure: OSI-774. San Francisco, CA, Genentech, Inc, 2001
    • (2001) Investigator's Brochure: OSI-774
  • 110
    • 0032533858 scopus 로고    scopus 로고
    • Expression of cyclooxygenase-2 in human lung carcinoma
    • Wolff H, Saukkonen K, Anttila S, et al: Expression of cyclooxygenase-2 in human lung carcinoma. Cancer Res 58:4997-5001, 1998
    • (1998) Cancer Res. , vol.58 , pp. 4997-5001
    • Wolff, H.1    Saukkonen, K.2    Anttila, S.3
  • 111
    • 0032170955 scopus 로고    scopus 로고
    • Increased expression of cyclooxygenase 2 occurs frequently in human lung cancers, specifically in adenocarcinomas
    • Hida T, Yatabe Y, Achiwa H, et al: Increased expression of cyclooxygenase 2 occurs frequently in human lung cancers, specifically in adenocarcinomas. Cancer Res 58:3761-3764, 1998
    • (1998) Cancer Res. , vol.58 , pp. 3761-3764
    • Hida, T.1    Yatabe, Y.2    Achiwa, H.3
  • 112
    • 0032948381 scopus 로고    scopus 로고
    • Prognostic significance of elevated cyclooxygenase 2 expression in primary, resected lung adenocarcinomas
    • Achiwa H, Yatabe Y, Hida T, et al: Prognostic significance of elevated cyclooxygenase 2 expression in primary, resected lung adenocarcinomas. Clin Cancer Res 5:1001-1005, 1999
    • (1999) Clin. Cancer Res. , vol.5 , pp. 1001-1005
    • Achiwa, H.1    Yatabe, Y.2    Hida, T.3
  • 113
    • 0034901568 scopus 로고    scopus 로고
    • Cyclooxygenase-2 overexpression is a marker of poor prognosis in stage I non-small cell lung cancer
    • Khuri FR, Wu H, Lee JJ, et al: Cyclooxygenase-2 overexpression is a marker of poor prognosis in stage I non-small cell lung cancer. Clin Cancer Res 7:861-867, 2001
    • (2001) Clin. Cancer Res. , vol.7 , pp. 861-867
    • Khuri, F.R.1    Wu, H.2    Lee, J.J.3
  • 114
    • 0034010844 scopus 로고    scopus 로고
    • Spatial requirements for 15-R-hydroxy-5Z, 8Z, 11Z, 13E-eicosatetraenoic acid synthesis within the cyclooxygenase active site of murine COX-2. Why acetylated COX-1 does not synthesize 15-R-HETE
    • Rowlinson SW, Crews BC, Goodwin DC, et al: Spatial requirements for 15-R-hydroxy-5Z, 8Z, 11Z, 13E-eicosatetraenoic acid synthesis within the cyclooxygenase active site of murine COX-2. Why acetylated COX-1 does not synthesize 15-R-HETE. J Biol Chem 275:6586-6591, 2000
    • (2000) J. Biol. Chem. , vol.275 , pp. 6586-6591
    • Rowlinson, S.W.1    Crews, B.C.2    Goodwin, D.C.3
  • 115
    • 0027197062 scopus 로고
    • Treatment of colonic and rectal adenomas with sulindac in familial adenomatous polyposis
    • Giardiello FM, Hamilton SR, Krush AJ, et al: Treatment of colonic and rectal adenomas with sulindac in familial adenomatous polyposis. N Engl J Med 328:1313-1316, 1993
    • (1993) N. Engl. J. Med. , vol.328 , pp. 1313-1316
    • Giardiello, F.M.1    Hamilton, S.R.2    Krush, A.J.3
  • 116
    • 0029150934 scopus 로고
    • Aspirin and the risk of colorectal cancer in women
    • Giovannucci E, Egan KM, Hunter DJ, et al: Aspirin and the risk of colorectal cancer in women. N Engl J Med 333:609-614, 1995
    • (1995) N. Engl. J. Med. , vol.333 , pp. 609-614
    • Giovannucci, E.1    Egan, K.M.2    Hunter, D.J.3
  • 117
    • 17744418769 scopus 로고    scopus 로고
    • The effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposis
    • Steinbach G, Lunch PM, Phillips RK, et al: The effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposis. N Engl J Med 342:1946-1952, 2000
    • (2000) N. Engl. J. Med. , vol.342 , pp. 1946-1952
    • Steinbach, G.1    Lunch, P.M.2    Phillips, R.K.3
  • 118
    • 0025998557 scopus 로고
    • Aspirin use and reduced risk of fatal colon cancer
    • Thun MJ, Namboodiri MM, Heath CW: Aspirin use and reduced risk of fatal colon cancer. N Engl J Med 325: 1593-1596, 1991
    • (1991) N. Engl. J. Med. , vol.325 , pp. 1593-1596
    • Thun, M.J.1    Namboodiri, M.M.2    Heath, C.W.3
  • 119
    • 0028325496 scopus 로고
    • Aspirin use and lung, colon, and breast cancer incidence in a prospective study
    • Schreinemachers DM, Everson RB: Aspirin use and lung, colon, and breast cancer incidence in a prospective study. Epidemiology 5:138-146, 1994
    • (1994) Epidemiology , vol.5 , pp. 138-146
    • Schreinemachers, D.M.1    Everson, R.B.2
  • 121
    • 0036632411 scopus 로고    scopus 로고
    • Chemoprevention of lung cancer by non-steroidal anti-inflammatory drugs among cigarette smokers
    • Harris RE, Beebe-Donk J, Schuller HM: Chemoprevention of lung cancer by non-steroidal anti-inflammatory drugs among cigarette smokers. Oncol Rep 9:693-695, 2002
    • (2002) Oncol. Rep. , vol.9 , pp. 693-695
    • Harris, R.E.1    Beebe-Donk, J.2    Schuller, H.M.3
  • 122
    • 0027452033 scopus 로고
    • Studies of the chemopreventive effects of myo-inositol on benzo[a]pyrene induced neoplasia of the lung and forestomach of female A/J mice
    • Estenser RD, Wattenberg LW: Studies of the chemopreventive effects of myo-inositol on benzo[a]pyrene induced neoplasia of the lung and forestomach of female A/J mice. Carcinogenesis 14:1975-1977, 1993
    • (1993) Carcinogenesis , vol.14 , pp. 1975-1977
    • Estenser, R.D.1    Wattenberg, L.W.2
  • 123
    • 0029046505 scopus 로고
    • Chalcones, myo-Inositol and other novel inhibitors of pulmonary carcinogenesis
    • Wattenberg L: Chalcones, myo-Inositol and other novel inhibitors of pulmonary carcinogenesis. J Cell Biochem Suppl 22:162-168, 1995
    • (1995) J. Cell Biochem. Suppl. , vol.22 , pp. 162-168
    • Wattenberg, L.1
  • 124
    • 0031454659 scopus 로고    scopus 로고
    • Chemoprevention of pulmonary carcinogenesis by aerosolized budesonide in female A/J mice
    • Wattenberg LW, Wiedmann TS, Estensen RD, et al: Chemoprevention of pulmonary carcinogenesis by aerosolized budesonide in female A/J mice. Cancer Res 57: 5489-5492, 1997
    • (1997) Cancer Res. , vol.57 , pp. 5489-5492
    • Wattenberg, L.W.1    Wiedmann, T.S.2    Estensen, R.D.3
  • 125
    • 0028874567 scopus 로고
    • Neuroendocrine involvement in aging: Evidence from studies of reproductive aging and caloric restriction
    • Nelson JF, Karelus K, Bergman MD, et al: Neuroendocrine involvement in aging: Evidence from studies of reproductive aging and caloric restriction. Neurobiol Aging 16:837-843, 1995
    • (1995) Neurobiol. Aging , vol.16 , pp. 837-843
    • Nelson, J.F.1    Karelus, K.2    Bergman, M.D.3
  • 126
    • 0024424290 scopus 로고
    • Dietary restriction, tumors, and aging in rodents
    • Weindruch R: Dietary restriction, tumors, and aging in rodents. J Gerontol 44:67-71, 1989
    • (1989) J. Gerontol. , vol.44 , pp. 67-71
    • Weindruch, R.1
  • 127
    • 0030954026 scopus 로고    scopus 로고
    • Characterization of early pulmonary hyperproliferation and tumor progression and their inhibition by black tea in a 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis model with A/J mice
    • Yang G, Wang ZY, Kim S, et al: Characterization of early pulmonary hyperproliferation and tumor progression and their inhibition by black tea in a 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis model with A/J mice. Cancer Res 57:1889-1894, 1997
    • (1997) Cancer Res. , vol.57 , pp. 1889-1894
    • Yang, G.1    Wang, Z.Y.2    Kim, S.3
  • 128
    • 0032785391 scopus 로고    scopus 로고
    • Green tea and cancer chemoprevention
    • Suganuma M, Okabe S, Sueoka N, et al: Green tea and cancer chemoprevention. Mutat Res 428:339-344, 1996
    • (1996) Mutat. Res. , vol.428 , pp. 339-344
    • Suganuma, M.1    Okabe, S.2    Sueoka, N.3
  • 130
    • 0013521845 scopus 로고    scopus 로고
    • Chemoprevention of lung adenomas by a VIP receptor antagonist
    • Moody T, You L, Jakowlew S, et al: Chemoprevention of lung adenomas by a VIP receptor antagonist. Proc Am Assoc Cancer Res 7:364, 1996
    • (1996) Proc. Am. Assoc. Cancer Res. , vol.7 , pp. 364
    • Moody, T.1    You, L.2    Jakowlew, S.3
  • 131
    • 0008644942 scopus 로고    scopus 로고
    • Chemoprevention strategies
    • Pass HI, Mitchell JB, Johnson DH, et al (eds): Philadelphia, PA, Lippincott-Raven Publishers
    • Huber MH, Lippman SM: Chemoprevention strategies, in Pass HI, Mitchell JB, Johnson DH, et al (eds): Lung Cancer: Principles and Practice. Philadelphia, PA, Lippincott-Raven Publishers, 1996, pp 351-358
    • (1996) Lung Cancer: Principles and Practice , pp. 351-358
    • Huber, M.H.1    Lippman, S.M.2
  • 132
    • 0345157579 scopus 로고    scopus 로고
    • Lack of long-term supplementation with beta-carotene on the incidence of malignant neoplasms and cardiovascular disease
    • Hennekans CH, Buring JE, Manson JE, et al: Lack of long-term supplementation with beta-carotene on the incidence of malignant neoplasms and cardiovascular disease. N Engl J Med 334:1145-1149, 1996
    • (1996) N. Engl. J. Med. , vol.334 , pp. 1145-1149
    • Hennekans, C.H.1    Buring, J.E.2    Manson, J.E.3
  • 133
    • 0010607277 scopus 로고
    • The effect of vitamin E and beta carotene on the incidence of lung cancer and other cancers in male smokers
    • The Alpha-Tocopherol, Beta Carotene Cancer Prevention Study Group
    • The Alpha-Tocopherol, Beta Carotene Cancer Prevention Study Group: The effect of vitamin E and beta carotene on the incidence of lung cancer and other cancers in male smokers. N Engl J Med 330:1029-1035, 1994
    • (1994) N. Engl. J. Med. , vol.330 , pp. 1029-1035
  • 134
    • 0028790698 scopus 로고
    • Beta-carotene, vitamin A, and lung cancer chemoprevention: Results of an intermediate endpoint study
    • McLarty JW, Holiday DB, Girard WM, et al: Beta-carotene, vitamin A, and lung cancer chemoprevention: Results of an intermediate endpoint study. Am J Clin Nutr 62(suppl 6):1431S-1438S, 1995
    • (1995) Am. J. Clin. Nutr. , vol.62 , Issue.SUPPL. 6
    • McLarty, J.W.1    Holiday, D.B.2    Girard, W.M.3
  • 135
    • 0026561819 scopus 로고
    • The effect of the synthetic retinoid etretinate on sputum cytology: Results from a randomized trial
    • Arnold AM, Browman GP, Levine MN, et al: The effect of the synthetic retinoid etretinate on sputum cytology: Results from a randomized trial. Br J Cancer 65:737-743, 1992
    • (1992) Br. J. Cancer , vol.65 , pp. 737-743
    • Arnold, A.M.1    Browman, G.P.2    Levine, M.N.3
  • 136
    • 0028280222 scopus 로고
    • Randomized placebo-controlled trial of isotretinoin in chemoprevention of bronchial squamous metaplasia
    • Lee JS, Lippman SM, Benner SE, et al: Randomized placebo-controlled trial of isotretinoin in chemoprevention of bronchial squamous metaplasia. J Clin Oncol 12:937-945, 1994
    • (1994) J. Clin. Oncol. , vol.12 , pp. 937-945
    • Lee, J.S.1    Lippman, S.M.2    Benner, S.E.3
  • 137
    • 0033875561 scopus 로고    scopus 로고
    • N-(4-hydroxyphenyl)-retinamide in the chemoprevention of squamous metaplasia and dysplasia of the bronchial epithelium
    • Kurie JM, Lee JS, Khuri FR, et al: N-(4-hydroxyphenyl)-retinamide in the chemoprevention of squamous metaplasia and dysplasia of the bronchial epithelium. Clin Cancer Res 6:2973-2979, 2000
    • (2000) Clin. Cancer Res. , vol.6 , pp. 2973-2979
    • Kurie, J.M.1    Lee, J.S.2    Khuri, F.R.3
  • 138
    • 0035880941 scopus 로고    scopus 로고
    • Effects of N-(4-hydroxyphenyl) retinamide on hTERT expression in the bronchial epithelium of cigarette smokers
    • Soria JC, Moon C, Wang L, et al: Effects of N-(4-hydroxyphenyl) retinamide on hTERT expression in the bronchial epithelium of cigarette smokers. J Natl Cancer Inst 93:1257-1263, 2001
    • (2001) J. Natl. Cancer Inst. , vol.93 , pp. 1257-1263
    • Soria, J.C.1    Moon, C.2    Wang, L.3
  • 139
    • 0037014797 scopus 로고    scopus 로고
    • A randomized phase IIb trial of anethole dithiolethione in smokers with bronchial dysplasia
    • Lam S, MacAulay C, le Riche J, et al: A randomized phase IIb trial of anethole dithiolethione in smokers with bronchial dysplasia. J Natl Cancer lost 93: 1001-1009, 2002
    • (2002) J. Natl. Cancer Inst. , vol.93 , pp. 1001-1009
    • Lam, S.1    MacAulay, C.2    le Riche, J.3
  • 140
    • 0035906224 scopus 로고    scopus 로고
    • Randomized phase III intergroup trial of isotretinoin to prevent second primary tumors in stage I non-small cell lung cancer
    • Lippman SM, Lee JJ, Karp DD, et al: Randomized phase III intergroup trial of isotretinoin to prevent second primary tumors in stage I non-small cell lung cancer. J Natl Cancer Inst 93:605-618, 2001
    • (2001) J. Natl. Cancer Inst. , vol.93 , pp. 605-618
    • Lippman, S.M.1    Lee, J.J.2    Karp, D.D.3
  • 141
    • 0027207575 scopus 로고
    • Adjuvant treatment of stage I lung cancer with high-dose vitamin A
    • Pastorino U, Infante M, Maioli M, et al: Adjuvant treatment of stage I lung cancer with high-dose vitamin A. J Clin Oncol 11:1216-1222, 1993
    • (1993) J. Clin. Oncol. , vol.11 , pp. 1216-1222
    • Pastorino, U.1    Infante, M.2    Maioli, M.3
  • 142
    • 0034697654 scopus 로고    scopus 로고
    • EUROSCAN, a randomized trial of vitamin A and N-acetyleysteine in patients with head and neck cancer or lung cancer
    • For the European Organization for Research and Treatment of Cancer Head and Neck and Lung Cancer Cooperative Groups
    • Van Zandwijk N, Dalesio O, Pasotino U, et al: EUROSCAN, a randomized trial of vitamin A and N-acetyleysteine in patients with head and neck cancer or lung cancer. For the European Organization for Research and Treatment of Cancer Head and Neck and Lung Cancer Cooperative Groups. J Natl Cancer Inst 92:977-986, 2000
    • (2000) J. Natl. Cancer Inst. , vol.92 , pp. 977-986
    • Van Zandwijk, N.1    Dalesio, O.2    Pasotino, U.3
  • 143
    • 0022436901 scopus 로고
    • Regression of bronchial epidermoid metaplasia in heavy smokers with etretinate treatment
    • Misset JL, Mathe G, Santelli G, et al: Regression of bronchial epidermoid metaplasia in heavy smokers with etretinate treatment. Cancer Detect Prev 9:167-170, 1986
    • (1986) Cancer Detect. Prev. , vol.9 , pp. 167-170
    • Misset, J.L.1    Mathe, G.2    Santelli, G.3
  • 144
    • 0025264310 scopus 로고
    • Cancer recurrence after resection: T1N0 non-small cell lung cancer
    • the Lung Cancer StudyGroup
    • Thomas P, Rubinstein L, the Lung Cancer StudyGroup: Cancer recurrence after resection: T1N0 non-small cell lung cancer. Ann Thorac Surg 49:242-246, 1990
    • (1990) Ann. Thorac. Surg. , vol.49 , pp. 242-246
    • Thomas, P.1    Rubinstein, L.2
  • 145
    • 0346605768 scopus 로고    scopus 로고
    • Current Clinical Trials: Oncology
    • Current Clinical Trials: Oncology. Natl Cancer Inst 3:199, 1996
    • (1996) Natl. Cancer Inst. , vol.3 , pp. 199
  • 147
    • 0003049937 scopus 로고    scopus 로고
    • Classification, histology, cytology, and electron microscopy
    • Pass HI, Mitchell JB, Johnson DH, et al (eds): Philadelphia, PA, Lippincott-Raven
    • Travis WD, Linder J, Machay B: Classification, histology, cytology, and electron microscopy, in Pass HI, Mitchell JB, Johnson DH, et al (eds): Lung Cancer: Principles and Practice. Philadelphia, PA, Lippincott-Raven, 1996, pp 361-395
    • (1996) Lung Cancer: Principles and Practice , pp. 361-395
    • Travis, W.D.1    Linder, J.2    Machay, B.3
  • 148
    • 0017464139 scopus 로고
    • Radiologically occult in situ and incipient invasive epidermoid lung cancer: Detection by sputum cytology in a survey of asymptomatic cigarette smokers
    • Melamed MR, Zaman MB, Flehinger BH, et al: Radiologically occult in situ and incipient invasive epidermoid lung cancer: Detection by sputum cytology in a survey of asymptomatic cigarette smokers. Am J Surg Pathol 1:5-16, 1977
    • (1977) Am. J. Surg. Pathol. , vol.1 , pp. 5-16
    • Melamed, M.R.1    Zaman, M.B.2    Flehinger, B.H.3
  • 149
    • 0022493426 scopus 로고
    • Sputum cytopathology: Use and potential in monitoring the workplace environment by screening for biological effects of explosure
    • Frost JK, Ball WC Jr, Levin ML, et al: Sputum cytopathology: Use and potential in monitoring the workplace environment by screening for biological effects of explosure. J Occup Med 28:692-703, 1986
    • (1986) J. Occup. Med. , vol.28 , pp. 692-703
    • Frost, J.K.1    Ball Jr., W.C.2    Levin, M.L.3
  • 150
    • 2842611627 scopus 로고    scopus 로고
    • Practice guidelines for non-small cell lung cancer
    • Cameron R, Fringer J, Taylor C, et al: Practice guidelines for non-small cell lung cancer. Cancer J Sci Am 2(suppl 3A):S69-S77, 1996
    • (1996) Cancer J. Sci. Am. , vol.2 , Issue.SUPPL. 3A
    • Cameron, R.1    Fringer, J.2    Taylor, C.3
  • 151
    • 0029097607 scopus 로고
    • Photodynamic therapy. Its use in the management of bronchogenic carcinoma
    • Edell ES, Cortese DA: Photodynamic therapy. Its use in the management of bronchogenic carcinoma. Clin Chest Med 16:455-463, 1995
    • (1995) Clin. Chest Med. , vol.16 , pp. 455-463
    • Edell, E.S.1    Cortese, D.A.2
  • 152
    • 85030917345 scopus 로고    scopus 로고
    • The American Association for Cancer Research. Boston, MA, October 14-18
    • Frontiers in Cancer Prevention Research The American Association for Cancer Research. Boston, MA, October 14-18, 2002
    • (2002) Frontiers in Cancer Prevention Research


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