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Volumn 7, Issue 2, 1996, Pages 133-141

The epidermal growth factor receptor and its ligands as therapeutic targets in human tumors

Author keywords

EGFR; Human tumors; Ligands; Therapeutic targets

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; MONOCLONAL ANTIBODY; TRANSFORMING GROWTH FACTOR ALPHA;

EID: 0030206987     PISSN: 13596101     EISSN: None     Source Type: Journal    
DOI: 10.1016/1359-6101(96)00016-0     Document Type: Short Survey
Times cited : (101)

References (64)
  • 1
    • 0025343230 scopus 로고
    • Signal transduction by receptors with tyrosine kinase activity
    • 1. Ullrich A, Schlessinger J. Signal transduction by receptors with tyrosine kinase activity. Cell 1990, 61, 203-212.
    • (1990) Cell , vol.61 , pp. 203-212
    • Ullrich, A.1    Schlessinger, J.2
  • 2
    • 0026793456 scopus 로고
    • Growth factor signaling by receptor tyrosine kinases
    • 2. Schlessinger J, Ullrich A. Growth factor signaling by receptor tyrosine kinases. Neuron 1992, 9, 383-391.
    • (1992) Neuron , vol.9 , pp. 383-391
    • Schlessinger, J.1    Ullrich, A.2
  • 3
    • 0025873538 scopus 로고
    • Epidermal growth factor (EGF) induces oligomerization of soluble, extracellular, ligand-binding domain of EGF receptor
    • 3. Lax I. Mitra AK, Ravera C et al. Epidermal growth factor (EGF) induces oligomerization of soluble, extracellular, ligand-binding domain of EGF receptor. J Biol Chem 1991, 266, 13828-13833.
    • (1991) J Biol Chem , vol.266 , pp. 13828-13833
    • Lax, I.1    Mitra, A.K.2    Ravera, C.3
  • 4
    • 0025836714 scopus 로고
    • EGF induces increased ligand binding affinity and dimerization of soluble epidermal growth factor (EGF) receptor extracellular domain
    • 4. Hurwitz DR, Emanuel SL, Nathan MH et al. EGF induces increased ligand binding affinity and dimerization of soluble epidermal growth factor (EGF) receptor extracellular domain. J Biol Chem 1991, 266, 22035-22043.
    • (1991) J Biol Chem , vol.266 , pp. 22035-22043
    • Hurwitz, D.R.1    Emanuel, S.L.2    Nathan, M.H.3
  • 5
    • 0024841734 scopus 로고
    • Epidermal growth factor binding induces a conformational change in the external domain of its receptor
    • 5. Greenfield C, Hiles I, Waterfield MD et al. Epidermal growth factor binding induces a conformational change in the external domain of its receptor. EMBO J 1989, 8, 4115-4123.
    • (1989) EMBO J , vol.8 , pp. 4115-4123
    • Greenfield, C.1    Hiles, I.2    Waterfield, M.D.3
  • 6
    • 0023686033 scopus 로고
    • Signal transduction by allosteric receptor oligomerization
    • 6. Schlessinger J. Signal transduction by allosteric receptor oligomerization. Trends Biochem Sci 1988, 13, 443-447.
    • (1988) Trends Biochem Sci , vol.13 , pp. 443-447
    • Schlessinger, J.1
  • 7
    • 0000317172 scopus 로고
    • Evidence that autophosphorylation of solubilized receptors for epidermal growth factor is mediated by intermolecular cross-phosphorylation
    • 7. Honnegger AM, Kris RM, Ullrich A, Schlessinger J. Evidence that autophosphorylation of solubilized receptors for epidermal growth factor is mediated by intermolecular cross-phosphorylation. Proc Natl Acad Sci USA 1989, 86, 925-929.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 925-929
    • Honnegger, A.M.1    Kris, R.M.2    Ullrich, A.3    Schlessinger, J.4
  • 8
    • 0025352677 scopus 로고
    • Evidence for epidermal growth factor (RGF)-induced inter-molecular autophosphorylation of the EGF receptors in living cells
    • 8. Honegger AM, Schmidt A, Ullrich A, Schlessiger J. Evidence for epidermal growth factor (RGF)-induced inter-molecular autophosphorylation of the EGF receptors in living cells. Molec Cell Biol 1990, 10, 4035-4044.
    • (1990) Molec Cell Biol , vol.10 , pp. 4035-4044
    • Honegger, A.M.1    Schmidt, A.2    Ullrich, A.3    Schlessiger, J.4
  • 9
    • 0028234529 scopus 로고
    • Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins
    • 9. Darnell JE Jr, Kerr IM, Stark GR. Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science 1994, 264, 1415-1421.
    • (1994) Science , vol.264 , pp. 1415-1421
    • Darnell J.E., Jr.1    Kerr, I.M.2    Stark, G.R.3
  • 10
    • 0028284762 scopus 로고
    • Stat3 and stat4: Members of the family of signal transducers and activators of transcription
    • 10. Zhong Z, Wen Z, Darnell JE Jr. Stat3 and Stat4: Members of the family of signal transducers and activators of transcription. Proc Natl Acad Sci USA 1994, 91, 4806-4810.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 4806-4810
    • Zhong, Z.1    Wen, Z.2    Darnell J.E., Jr.3
  • 11
    • 0028946158 scopus 로고
    • Contribution of STAT SH2 groups to specific interferon signaling by the Jak-STAT pathway
    • 11. Heim MH, Kerr IM, Stark GR, Darnell Jr JE. Contribution of STAT SH2 groups to specific Interferon signaling by the Jak-STAT pathway. Science 1995, 267, 1347-1349.
    • (1995) Science , vol.267 , pp. 1347-1349
    • Heim, M.H.1    Kerr, I.M.2    Stark, G.R.3    Darnell J.E., Jr.4
  • 12
    • 0027772891 scopus 로고
    • Polypeptide signalling to the nucleus through tyrosine phosphorylation of Jaka and stat proteins
    • 12. Shuai K, Ziemiecki A, Wilks AF et al. Polypeptide signalling to the nucleus through tyrosine phosphorylation of Jaka and Stat proteins. Nature 1993, 366, 580-582.
    • (1993) Nature , vol.366 , pp. 580-582
    • Shuai, K.1    Ziemiecki, A.2    Wilks, A.F.3
  • 13
    • 0029061508 scopus 로고
    • Tyrosine-phosphorylated stat1 and stat2 plus a 48-kDa protein all contact DNA in forming interferon-stimulated-gene factor 3
    • 13. Qureshi SA, Salditt-Georgieff M, Darnell Jr JE. Tyrosine-phosphorylated Stat1 and Stat2 plus a 48-kDa protein all contact DNA in forming interferon-stimulated-gene factor 3. Proc Natl Acad Sci USA 1995, 92, 3829-3833.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 3829-3833
    • Qureshi, S.A.1    Salditt-Georgieff, M.2    Darnell J.E., Jr.3
  • 14
    • 0028349735 scopus 로고
    • Stat3: A STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6
    • 14. Zhong Z, Wen Z, Darnell JE Jr. Stat3: A STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6. Science 1994, 264, 95-98.
    • (1994) Science , vol.264 , pp. 95-98
    • Zhong, Z.1    Wen, Z.2    Darnell J.E., Jr.3
  • 15
    • 0025368610 scopus 로고
    • Growth stimulation by coexpression of transforming growth factor-α and epidermal growth factor-receptor in normal adenomatous human colon epithelium
    • 15. Markowitz SD, Molkentin K, Gerbic C, Jackson J, Stellato T, Willson JKV. Growth stimulation by coexpression of transforming growth factor-α and epidermal growth factor-receptor in normal adenomatous human colon epithelium. J Clin Invest 1990, 86, 356-362.
    • (1990) J Clin Invest , vol.86 , pp. 356-362
    • Markowitz, S.D.1    Molkentin, K.2    Gerbic, C.3    Jackson, J.4    Stellato, T.5    Willson, J.K.V.6
  • 16
    • 0022481299 scopus 로고
    • Expression in rat fibroblasts of a human transforming growth factor-α cDNA results in transformation
    • 16. Rosenthal A, Lindquist PB, Bringman TS, Goeddel DV, Derynck R. Expression in rat fibroblasts of a human transforming growth factor-α cDNA results in transformation. Cell 1986, 46, 301-309.
    • (1986) Cell , vol.46 , pp. 301-309
    • Rosenthal, A.1    Lindquist, P.B.2    Bringman, T.S.3    Goeddel, D.V.4    Derynck, R.5
  • 17
    • 0344127372 scopus 로고
    • Ligand activation of overexpressed epidermal growth factor receptors transforms NIH 3T3 mouse fibroblasts
    • 17. Riedel H, Massoglia S, Schlessinger J, Ullrich A. Ligand activation of overexpressed epidermal growth factor receptors transforms NIH 3T3 mouse fibroblasts. Proc Natl Acad Sci USA 1986, 85, 1477-1481.
    • (1986) Proc Natl Acad Sci USA , vol.85 , pp. 1477-1481
    • Riedel, H.1    Massoglia, S.2    Schlessinger, J.3    Ullrich, A.4
  • 18
    • 0024551794 scopus 로고
    • Transforming growth factor α production and epidermal growth factor receptor expression in normal and oncogene transformed human mammary epithelial cells
    • 18. Valverius EM, Bates SE, Stampfer MR et al. Transforming growth factor α production and epidermal growth factor receptor expression in normal and oncogene transformed human mammary epithelial cells. Molec Endocr. 1989, 3, 203-214.
    • (1989) Molec Endocr. , vol.3 , pp. 203-214
    • Valverius, E.M.1    Bates, S.E.2    Stampfer, M.R.3
  • 19
    • 0025297086 scopus 로고
    • Overexpression of TGFα in transgenic mice: Induction of epithelial hyperplasia, pancreatic metaplasia, and carcinoma of the breast
    • 19. Sandgren EP, Luetteke NC, Palmiter RD, Brinster RL, Lee DC. Overexpression of TGFα in transgenic mice: Induction of epithelial hyperplasia, pancreatic metaplasia, and carcinoma of the breast. Cell 1990, 61, 1121-1135.
    • (1990) Cell , vol.61 , pp. 1121-1135
    • Sandgren, E.P.1    Luetteke, N.C.2    Palmiter, R.D.3    Brinster, R.L.4    Lee, D.C.5
  • 20
    • 0024355092 scopus 로고
    • Autocrine interaction between TGF-α and the EGF-receptor: Quantitative requirements for induction of the malignant phenotype
    • 20. Di Marco E, Pierce JH, Fleming TP et al. Autocrine interaction between TGF-α and the EGF-receptor: quantitative requirements for induction of the malignant phenotype. Oncogene 1989, 4, 831-838.
    • (1989) Oncogene , vol.4 , pp. 831-838
    • Di Marco, E.1    Pierce, J.H.2    Fleming, T.P.3
  • 21
    • 0027283717 scopus 로고
    • Blockage of EGF receptor signal transduction causes reversible arrest of normal and immortal human mammary epithelial cells with synchronous reentry into the cell cycle
    • 21. Stampfer MR, Pan CG, Hosoda J, Bartholemew J, Mendelsohn J, Yaswen P. Blockage of EGF receptor signal transduction causes reversible arrest of normal and immortal human mammary epithelial cells with synchronous reentry into the cell cycle. Exp Cell Res 1993, 208, 175-188.
    • (1993) Exp Cell Res , vol.208 , pp. 175-188
    • Stampfer, M.R.1    Pan, C.G.2    Hosoda, J.3    Bartholemew, J.4    Mendelsohn, J.5    Yaswen, P.6
  • 22
    • 0028969852 scopus 로고
    • Apoptosis induced by an anti-epidermal growth factor receptor monoclonal antibody in a human colorectal carcinoma cell line and its delay by insulin
    • 22. Wu X, Fan Z, Masui H, Rosen N, Mendelsohn J. Apoptosis induced by an anti-epidermal growth factor receptor monoclonal antibody in a human colorectal carcinoma cell line and its delay by insulin. J Clin invest 1995, 95, 1897-1905.
    • (1995) J Clin Invest , vol.95 , pp. 1897-1905
    • Wu, X.1    Fan, Z.2    Masui, H.3    Rosen, N.4    Mendelsohn, J.5
  • 23
    • 0029670014 scopus 로고    scopus 로고
    • 1 arrest mediated by an anti-epidermal growth factor receptor monoclonal antibody
    • 1 arrest mediated by an anti-epidermal growth factor receptor monoclonal antibody. Oncogene 1996, 12, 1397-1403.
    • (1996) Oncogene , vol.12 , pp. 1397-1403
    • Wu, X.1    Rubin, M.2    Fan, Z.3
  • 24
    • 0028980376 scopus 로고
    • Cip1/WAF1/CDK2/PCNA complex by epidermal growth factor receptor activation mediates ligand-induced A431 cell growth inhibition
    • Cip1/WAF1/CDK2/PCNA complex by epidermal growth factor receptor activation mediates ligand-induced A431 cell growth inhibition. J. Cell Biol 1995, 131, 235-242.
    • (1995) J. Cell Biol , vol.131 , pp. 235-242
    • Fan, Z.1    Lu, Y.2    Wu, X.3    DeBlasio, A.4    Koff, A.5    Mendelsohn, J.6
  • 25
    • 0028937815 scopus 로고
    • Epidermal growth factor receptor (EGFr) expression in non-small cell lung carcinomas correlates with metastatic involvement of hilar and mediastinal lymph nodes in the squamous subtype
    • 25. Fontanini G, Vignati S, Bigini D et al. Epidermal growth factor receptor (EGFr) expression in non-small cell lung carcinomas correlates with metastatic involvement of hilar and mediastinal lymph nodes in the squamous subtype. Eur J Cancer 1995, 31A, 178-183.
    • (1995) Eur J Cancer , vol.31 A , pp. 178-183
    • Fontanini, G.1    Vignati, S.2    Bigini, D.3
  • 26
    • 84920241849 scopus 로고    scopus 로고
    • Epidermal growth-factor receptors in human bladder cancer: Comparison of invasive and superficial tumours
    • 26. Neal DE, Bennett MK, Hall RR et al. Epidermal growth-factor receptors in human bladder cancer: Comparison of invasive and superficial tumours. Lancet 1998, i, 366-368.
    • (1998) Lancet , vol.1 , pp. 366-368
    • Neal, D.E.1    Bennett, M.K.2    Hall, R.R.3
  • 27
    • 0026340050 scopus 로고
    • Clinical significance of the expression of epidermal growth factor and its receptor in oesophageal cancer
    • 27. Mukaida H, Toi M, Hirai T, Yamashita Y, Toge T. Clinical significance of the expression of epidermal growth factor and its receptor in oesophageal cancer. Cancer 1991, 68, 142-148.
    • (1991) Cancer , vol.68 , pp. 142-148
    • Mukaida, H.1    Toi, M.2    Hirai, T.3    Yamashita, Y.4    Toge, T.5
  • 28
    • 0026098831 scopus 로고
    • Epidermal growth factor receptor (EGFr); results of a 6 year follow-up study in operable breast cancer with emphasis on the node negative subgroup
    • 28. Nichólson S, Richard J, Sainsbury C et al. Epidermal growth factor receptor (EGFr); results of a 6 year follow-up study in operable breast cancer with emphasis on the node negative subgroup. Br J Cancer 1991, 63, 146-150.
    • (1991) Br J Cancer , vol.63 , pp. 146-150
    • Nichólson, S.1    Richard, J.2    Sainsbury, C.3
  • 29
    • 0023835619 scopus 로고
    • Epidermal growth factor receptor expression in human lung cancer cell lines
    • 29. Haeder M, Rotsch M, Bepler G et al. Epidermal growth factor receptor expression in human lung cancer cell lines. Cancer Res 1988, 48, 1132-1136.
    • (1988) Cancer Res , vol.48 , pp. 1132-1136
    • Haeder, M.1    Rotsch, M.2    Bepler, G.3
  • 30
    • 0026734656 scopus 로고
    • Expression of the epidermal growth factor receptor in human small cell lung cancer cell lines
    • 30. Damstrup L, Rygaard K, Spang-Thomsen M, Poulsen HS. Expression of the epidermal growth factor receptor in human small cell lung cancer cell lines. Cancer Res 1992, 52, 3089-3094.
    • (1992) Cancer Res , vol.52 , pp. 3089-3094
    • Damstrup, L.1    Rygaard, K.2    Spang-Thomsen, M.3    Poulsen, H.S.4
  • 31
    • 0023100052 scopus 로고
    • Synthesis of messenger RNAs for transforming growth factors α and β and the epidermal growth factor by human tumors
    • 31. Derynck R, Goeddel DV, Ullruch A et al. Synthesis of messenger RNAs for transforming growth factors α and β and the epidermal growth factor by human tumors. Cancer Res 1987, 47, 707-712.
    • (1987) Cancer Res , vol.47 , pp. 707-712
    • Derynck, R.1    Goeddel, D.V.2    Ullruch, A.3
  • 32
    • 0024438120 scopus 로고
    • Expression of epidermal growth factor receptors in four histologic cell types of lung cancer
    • 32. Kaseda S, Ueda M, Ozawa S, Ishihara T, Abe O, Shimizu N. Expression of epidermal growth factor receptors in four histologic cell types of lung cancer. J Surg Oncol 1989, 42, 16-20.
    • (1989) J Surg Oncol , vol.42 , pp. 16-20
    • Kaseda, S.1    Ueda, M.2    Ozawa, S.3    Ishihara, T.4    Abe, O.5    Shimizu, N.6
  • 33
    • 0027372451 scopus 로고
    • Epidermal growth factor receptor expression in squamous cell lung carcinomas: An immunohistochemical and gene analysis in formalin-fixed, paraffin-embedded material
    • 33. Gorgoulis V, Giatromanolaki A, Karameris A et al. Epidermal growth factor receptor expression in squamous cell lung carcinomas: An immunohistochemical and gene analysis in formalin-fixed, paraffin-embedded material. Virchows Arch A Path Anat Histol 1993, 423, 295-302.
    • (1993) Virchows Arch A Path Anat Histol , vol.423 , pp. 295-302
    • Gorgoulis, V.1    Giatromanolaki, A.2    Karameris, A.3
  • 35
    • 0026801871 scopus 로고
    • Expression of EFG, TGF-α and EGFR in squamous cell lung carcinomas
    • 35. Gorgoulis V, Aninos D, Mikou P et al. Expression of EFG, TGF-α and EGFR in squamous cell lung carcinomas. Anticancer Res 1992, 12, 1183-1188.
    • (1992) Anticancer Res , vol.12 , pp. 1183-1188
    • Gorgoulis, V.1    Aninos, D.2    Mikou, P.3
  • 36
    • 0024399929 scopus 로고
    • Expression of epidermal growth factor receptor (EGF-R) in non-small cell lung cancer. Use of archival tissue and correlation of EGF-R with histology, tumour size, node status and survival
    • 36. Dazzi H, Hasleton PS, Thatcher N et al. Expression of epidermal growth factor receptor (EGF-R) in non-small cell lung cancer. Use of archival tissue and correlation of EGF-R with histology, tumour size, node status and survival. Br J Cancer 1989, 59, 746-749.
    • (1989) Br J Cancer , vol.59 , pp. 746-749
    • Dazzi, H.1    Hasleton, P.S.2    Thatcher, N.3
  • 37
    • 0025013846 scopus 로고
    • Immunohistochemical evidence of autocrine growth factors in adenocarcinoma of the human lung
    • 37. Tateishi M, Ishida T, Mitsudomi T, Kaneko S, Sugimachi K. Immunohistochemical evidence of autocrine growth factors in adenocarcinoma of the human lung. Cancer Res 1990, 50, 7077-7080.
    • (1990) Cancer Res , vol.50 , pp. 7077-7080
    • Tateishi, M.1    Ishida, T.2    Mitsudomi, T.3    Kaneko, S.4    Sugimachi, K.5
  • 38
  • 39
    • 0027232422 scopus 로고
    • The relationship of quantitative epidermal growth factor receptor expression in non-small cell lung cancer to long term survival
    • 39. Veale D, Kerr N, Gibson GJ, Kelly PJ, Harris AL. The relationship of quantitative epidermal growth factor receptor expression in non-small cell lung cancer to long term survival. Br J Cancer 1993, 68, 162-165.
    • (1993) Br J Cancer , vol.68 , pp. 162-165
    • Veale, D.1    Kerr, N.2    Gibson, G.J.3    Kelly, P.J.4    Harris, A.L.5
  • 40
    • 0023192376 scopus 로고
    • Epidermal growth factor receptor expression in human lung carcinomas defined by a monoclonal antibody
    • 40. Sobol RD, Astarita RW, Hofeditz C et al. Epidermal growth factor receptor expression in human lung carcinomas defined by a monoclonal antibody. J Nat Cancer Inst 1987, 79, 403-407.
    • (1987) J Nat Cancer Inst , vol.79 , pp. 403-407
    • Sobol, R.D.1    Astarita, R.W.2    Hofeditz, C.3
  • 41
    • 0023036651 scopus 로고
    • Expression of epidermal growth factor receptors in human lung tumors
    • 41. Hwang DL, Tay Y-C, Lin SS, Lev-Ran A. Expression of epidermal growth factor receptors in human lung tumors. Cancer 1986, 58, 2260-2263.
    • (1986) Cancer , vol.58 , pp. 2260-2263
    • Hwang, D.L.1    Tay, Y.-C.2    Lin, S.S.3    Lev-Ran, A.4
  • 42
    • 0023688043 scopus 로고
    • Multiple restriction fragment length polymorphisms of the human epidermal growth factor receptor gene
    • 42. Lee JS, Ro JS, Eisbruch A et al. Multiple restriction fragment length polymorphisms of the human epidermal growth factor receptor gene. Cancer Res 1988, 48, 4045-4048.
    • (1988) Cancer Res , vol.48 , pp. 4045-4048
    • Lee, J.S.1    Ro, J.S.2    Eisbruch, A.3
  • 43
    • 0011206753 scopus 로고
    • Expression of epidermal growth factor receptor (EGFR): A favorable prognostic factor for surgically resected non-small cell lung cancer
    • Abstract
    • 43. Lee JS, Ro JY, Sahin A, Hittelman W. Expression of epidermal growth factor receptor (EGFR): A favorable prognostic factor for surgically resected non-small cell lung cancer. Proc ASCO 1989, 8, A878 (Abstract).
    • (1989) Proc ASCO , vol.8
    • Lee, J.S.1    Ro, J.Y.2    Sahin, A.3    Hittelman, W.4
  • 44
    • 0027159063 scopus 로고
    • Differential expression of the epidermal growth factor receptor and its ligands in primary non-small cell lung cancers and adjacent benign lung
    • 44. Rusch V, Vaselga J, Cordon-Cardo C et al. Differential expression of the epidermal growth factor receptor and its ligands in primary non-small cell lung cancers and adjacent benign lung. Cancer Res 1993, 53, 2379-2385.
    • (1993) Cancer Res , vol.53 , pp. 2379-2385
    • Rusch, V.1    Vaselga, J.2    Cordon-Cardo, C.3
  • 45
    • 0028913802 scopus 로고
    • Aberrant expression of p53 or the epidermal growth factor receptor is frequent in early bronchial neoplasia, and coexpression precedes squamous cell carcinoma development
    • 45. Rusch V, Klimstra D, Linkov I, Dmitrovsky E. Aberrant expression of p53 or the epidermal growth factor receptor is frequent in early bronchial neoplasia, and coexpression precedes squamous cell carcinoma development. Cancer Res 1995, 55, 1365-1372.
    • (1995) Cancer Res , vol.55 , pp. 1365-1372
    • Rusch, V.1    Klimstra, D.2    Linkov, I.3    Dmitrovsky, E.4
  • 46
    • 0027538862 scopus 로고
    • Anti-tumor activity of combinations of antibodies directed against different epitopes on the extracellular domain of the human EGF receptor
    • 46. Modjtahedi H, Eccles SA, Box G, Styles J, Dean CJ. Anti-tumor activity of combinations of antibodies directed against different epitopes on the extracellular domain of the human EGF receptor. Cell Biophys 1993, 22, 129-146.
    • (1993) Cell Biophys , vol.22 , pp. 129-146
    • Modjtahedi, H.1    Eccles, S.A.2    Box, G.3    Styles, J.4    Dean, C.J.5
  • 48
    • 0024261027 scopus 로고
    • Efficacy of antibodies to epidermal growth factor receptor against KB carcinoma in vitro and in nude mice
    • 48. Aboud-Pirak E, Hurwitz E, Pirak ME, Bellot F, Schlessinger J, Sela M. Efficacy of antibodies to epidermal growth factor receptor against KB carcinoma In vitro and in nude mice. J Nat Cancer Inst 1988, 82, 1605-1611.
    • (1988) J Nat Cancer Inst , vol.82 , pp. 1605-1611
    • Aboud-Pirak, E.1    Hurwitz, E.2    Pirak, M.E.3    Bellot, F.4    Schlessinger, J.5    Sela, M.6
  • 49
    • 0021363327 scopus 로고
    • Growth inhibition of human tumor cells in thymic mice and anti-epidermal growth factor receptor monoclonal antibodies
    • 49. Masui H, Kawamoto T, Sato JD, Wolf B, Sato G, Mendelsohn J. Growth inhibition of human tumor cells in thymic mice and anti-epidermal growth factor receptor monoclonal antibodies. Cancer Res 1984, 44, 1002-1007.
    • (1984) Cancer Res , vol.44 , pp. 1002-1007
    • Masui, H.1    Kawamoto, T.2    Sato, J.D.3    Wolf, B.4    Sato, G.5    Mendelsohn, J.6
  • 50
    • 0028116305 scopus 로고
    • Antibody-induced epidermal growth factor receptor dimerization mediates inhibition of autocrine proliferation of A431 squamous carcinoma cells
    • 50. Fan Z, Lu Y, Wu X, Mendelsohn J. Antibody-induced epidermal growth factor receptor dimerization mediates inhibition of autocrine proliferation of A431 squamous carcinoma cells. J Biol Chem 1994, 269, 27595-27602.
    • (1994) J Biol Chem , vol.269 , pp. 27595-27602
    • Fan, Z.1    Lu, Y.2    Wu, X.3    Mendelsohn, J.4
  • 51
    • 0022999284 scopus 로고
    • Mechanism of anti-tumour activity in mice for anti-epidermal growth factor receptor monoclonal antibodies with different isotypes
    • 51. Masui H, Moroyama T, Mendelsohn J. Mechanism of anti-tumour activity in mice for anti-epidermal growth factor receptor monoclonal antibodies with different isotypes. Cancer Res 1986, 46, 5592-5598.
    • (1986) Cancer Res , vol.46 , pp. 5592-5598
    • Masui, H.1    Moroyama, T.2    Mendelsohn, J.3
  • 52
    • 0028208423 scopus 로고
    • Tumor epidermal growth factor receptor studies in patients with non-small-cell lung cancer or head and neck cancer treated with monoclonal antibody RG 83852
    • 52. Perez-Soler R, Donato NJ, Shin DM et al. Tumor epidermal growth factor receptor studies in patients with non-small-cell lung cancer or head and neck cancer treated with monoclonal antibody RG 83852. J Clin Oncol 1994, 12, 730-739.
    • (1994) J Clin Oncol , vol.12 , pp. 730-739
    • Perez-Soler, R.1    Donato, N.J.2    Shin, D.M.3
  • 53
    • 0026426157 scopus 로고
    • Phase I and imaging trial of indium 111-labeled anti-epidermal growth factor receptor monoclonal antibody 225 in patients with squamous cell lung carcinoma
    • 53. Divgi CR, Welt S, Kris M et al. Phase I and imaging trial of indium 111-labeled anti-epidermal growth factor receptor monoclonal antibody 225 in patients with squamous cell lung carcinoma. J Nat Cancer Inst 1991, 83, 97-104.
    • (1991) J Nat Cancer Inst , vol.83 , pp. 97-104
    • Divgi, C.R.1    Welt, S.2    Kris, M.3
  • 54
    • 0023223082 scopus 로고
    • Toxicity of ligand and antibody-directed ricin a-chain conjugates recognizing the epidermal growth factor receptor
    • 54. Vollmar AM, Banker DE, Mendelsohn J, Herschman HR. Toxicity of ligand and antibody-directed ricin a-chain conjugates recognizing the epidermal growth factor receptor. J Cell Physiol 1987, 131, 418-425.
    • (1987) J Cell Physiol , vol.131 , pp. 418-425
    • Vollmar, A.M.1    Banker, D.E.2    Mendelsohn, J.3    Herschman, H.R.4
  • 55
    • 0024586031 scopus 로고
    • Selective killings of squamous carcinoma cells by an immunotoxin that recognizes the EGF receptor
    • 55. Ozawa S, Ueda M, Ando N, Abe O, Minoshima S, Shimizu N. Selective killings of squamous carcinoma cells by an immunotoxin that recognizes the EGF receptor. Int J Cancer 1989, 43, 152-157.
    • (1989) Int J Cancer , vol.43 , pp. 152-157
    • Ozawa, S.1    Ueda, M.2    Ando, N.3    Abe, O.4    Minoshima, S.5    Shimizu, N.6
  • 56
    • 0028176709 scopus 로고
    • Selective toxicity of TGF-α-PE40 to EGFR-positive cell lines: Selective protection of low EGFR-expressing cell lines by EGF
    • 56. Kirk J, Carmichael J, Stratford IJ, Harris AL. Selective toxicity of TGF-α-PE40 to EGFR-positive cell lines: selective protection of low EGFR-expressing cell lines by EGF. Br J Cancer 1994, 69, 988-994.
    • (1994) Br J Cancer , vol.69 , pp. 988-994
    • Kirk, J.1    Carmichael, J.2    Stratford, I.J.3    Harris, A.L.4
  • 57
    • 0027290650 scopus 로고
    • Antitumor effects of doxorubicin in combination with anti-epidermal growth factor receptor monoclonal antibodies
    • 57. Baselga J, Norton L, Masui H et al. Antitumor effects of doxorubicin in combination with anti-epidermal growth factor receptor monoclonal antibodies. J Nat Cancer Inst 1993, 85, 1327-1333.
    • (1993) J Nat Cancer Inst , vol.85 , pp. 1327-1333
    • Baselga, J.1    Norton, L.2    Masui, H.3
  • 58
    • 0027428571 scopus 로고
    • Antitumor effect of anti-EGF receptor monoclonal antibodies plus cis-diamminedichloroplatinum (cis-DDP) on well established A431 cell xenografts
    • 58. Fan Z, Baselga J, Masui H, Mendelsohn J. Antitumor effect of anti-EGF receptor monoclonal antibodies plus cis-Diamminedichloroplatinum (cis-DDP) on well established A431 cell xenografts. Cancer Res 1993, 53, 4637-4642.
    • (1993) Cancer Res , vol.53 , pp. 4637-4642
    • Fan, Z.1    Baselga, J.2    Masui, H.3    Mendelsohn, J.4
  • 59
    • 0028180234 scopus 로고
    • 4,5-Dianilinophthalimide: A protein-tyrosine kinase inhibitor with selectivity for the epidermal growth factor receptor signal transduction pathway and potent in vivo antitumor activity
    • 59. Buchdunger E, Trinks U, Mett H et al. 4,5-Dianilinophthalimide: A protein-tyrosine kinase inhibitor with selectivity for the epidermal growth factor receptor signal transduction pathway and potent in vivo antitumor activity. Proc Natl Acad Sci USA 1994, 91, 2334-2338.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 2334-2338
    • Buchdunger, E.1    Trinks, U.2    Mett, H.3
  • 60
    • 0029123125 scopus 로고
    • Tyrosine kinase inhibitors. 7, 7-amino-4-(phenylamino)- and 7-amino-4-[(phenylmethyl)amino]pyrido [4,3-d]pyrimidmes: A new class of inhibitors of the tyrosine kinase activity of the epidermal growth factor receptor
    • 60. Thompson AM, Bridges AJ, Fry DW, Kraker AJ, Denny WA. Tyrosine kinase inhibitors. 7, 7-amino-4-(phenylamino)- and 7-amino-4-[(phenylmethyl)amino]pyrido [4,3-d]pyrimidmes: A new class of inhibitors of the tyrosine kinase activity of the epidermal growth factor receptor. J Med Chem 1995, 38, 3780-3788.
    • (1995) J Med Chem , vol.38 , pp. 3780-3788
    • Thompson, A.M.1    Bridges, A.J.2    Fry, D.W.3    Kraker, A.J.4    Denny, W.A.5
  • 61
    • 0028096596 scopus 로고
    • Design of a potent peptide inhibitor of the epidermal growth factor receptor tyrosine kinase utilizing sequences based on the natural phosphorylation sites of phospholipase C-γ 1
    • 61. Fry DW, McMichael A, Singh J, Dobrusin EM, McNamara DJ. Design of a potent peptide inhibitor of the epidermal growth factor receptor tyrosine kinase utilizing sequences based on the natural phosphorylation sites of phospholipase C-γ 1. Peptides 1994, 15, 951-957.
    • (1994) Peptides , vol.15 , pp. 951-957
    • Fry, D.W.1    McMichael, A.2    Singh, J.3    Dobrusin, E.M.4    McNamara, D.J.5
  • 62
    • 0029081718 scopus 로고
    • Inhibition of ligand-induced activation of epidermal growth factor receptor tyrosine phosphorylation by curcumin
    • 62. Korutla L, Cheung JY, Mendelsohn J, Kumar R. Inhibition of ligand-induced activation of epidermal growth factor receptor tyrosine phosphorylation by curcumin, Carcinogenesis 1995, 16, 1741-1745.
    • (1995) Carcinogenesis , vol.16 , pp. 1741-1745
    • Korutla, L.1    Cheung, J.Y.2    Mendelsohn, J.3    Kumar, R.4
  • 63
    • 0027198702 scopus 로고
    • Selective inhibition of the epidermal growth factor and HER2/neu receptors by tyrphostins
    • 63. Osherov N, Gazit A, Gilon C, Levitzki A. Selective inhibition of the epidermal growth factor and HER2/Neu receptors by tyrphostins. J Biol Chem 1993, 268, 11134-11142.
    • (1993) J Biol Chem , vol.268 , pp. 11134-11142
    • Osherov, N.1    Gazit, A.2    Gilon, C.3    Levitzki, A.4
  • 64
    • 0028142387 scopus 로고
    • A specific inhibitor of the epidermal growth factor receptor kinase
    • 64. Fry DW, Kraker AJ, McMichael A et al. A specific inhibitor of the epidermal growth factor receptor kinase. Science 1994, 265, 1093-1095.
    • (1994) Science , vol.265 , pp. 1093-1095
    • Fry, D.W.1    Kraker, A.J.2    McMichael, A.3


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