메뉴 건너뛰기




Volumn 2, Issue 11, 1996, Pages 468-475

Juvenile myelomonocytic leukemia: Molecular understanding and prospects for therapy

Author keywords

[No Author keywords available]

Indexed keywords

NEUROFIBROMIN; PROTEIN; RAS PROTEIN;

EID: 0030280090     PISSN: 13574310     EISSN: None     Source Type: Journal    
DOI: 10.1016/1357-4310(96)10044-7     Document Type: Review
Times cited : (74)

References (40)
  • 1
    • 12444338289 scopus 로고
    • Chronic leukemias of childhood
    • Pizzo, P.A. and Poplack, D.G., eds, J.B. Lippincott
    • Altman, A.J. (1993) Chronic leukemias of childhood, in Principles and Practice of Pediatric Oncology (Pizzo, P.A. and Poplack, D.G., eds), pp. 501-518, J.B. Lippincott
    • (1993) Principles and Practice of Pediatric Oncology , pp. 501-518
    • Altman, A.J.1
  • 2
    • 0016365161 scopus 로고
    • Juvenile 'chronic granulocytic leukemia': A panmyelopathy with prominent monocytic involvement and circulating monocyte colony-forming cells
    • Altman, A.J., Palmer, C.G. and Baehner, R.L. (1974) Juvenile 'chronic granulocytic leukemia': A panmyelopathy with prominent monocytic involvement and circulating monocyte colony-forming cells, Blood 43, 341-350
    • (1974) Blood , vol.43 , pp. 341-350
    • Altman, A.J.1    Palmer, C.G.2    Baehner, R.L.3
  • 3
    • 0021233189 scopus 로고
    • Subacute and chronic myelomonocytic leukemia in children (juvenile CML). Clinical and hematologic observations, and identification of prognostic factors
    • Castro-Malaspina, H. et al. (1984) Subacute and chronic myelomonocytic leukemia in children (juvenile CML). Clinical and hematologic observations, and identification of prognostic factors, Cancer 54, 675-686
    • (1984) Cancer , vol.54 , pp. 675-686
    • Castro-Malaspina, H.1
  • 4
    • 0022446552 scopus 로고
    • Juvenile chronic myelogenous leukemia: Characterization of the disease using cell cultures
    • Estrov, Z., Grunberger, T., Chan, H.S.L. and Freedman, M.H. (1986) Juvenile chronic myelogenous leukemia: characterization of the disease using cell cultures, Blood 67, 1382-1387
    • (1986) Blood , vol.67 , pp. 1382-1387
    • Estrov, Z.1    Grunberger, T.2    Chan, H.S.L.3    Freedman, M.H.4
  • 5
    • 0028910402 scopus 로고
    • Childhood monosomy 7: Epidemiology, biology and mechanistic implications
    • Luna-Fineman, S., Shannon, K.M. and Lange, B.J. (1995) Childhood monosomy 7: epidemiology, biology and mechanistic implications, Blood 85, 1985-1999
    • (1995) Blood , vol.85 , pp. 1985-1999
    • Luna-Fineman, S.1    Shannon, K.M.2    Lange, B.J.3
  • 6
    • 0020570416 scopus 로고
    • Persistent Epstein-Barr virus infection mimicking juvenile chronic myelogenous leukemia: Immunologic and hematologic studies
    • Herrod, H.G., Dow, L.W. and Sullivan, J.L. (1983) Persistent Epstein-Barr virus infection mimicking juvenile chronic myelogenous leukemia: immunologic and hematologic studies, Blood 61, 1098-1104
    • (1983) Blood , vol.61 , pp. 1098-1104
    • Herrod, H.G.1    Dow, L.W.2    Sullivan, J.L.3
  • 7
    • 0025076516 scopus 로고
    • Juvenile chronic myelogenous leukemia: Differentiation from infantile cytomegalovirus infection
    • Kirby, M.A., Weitzman, S. and Freedman, M.H. (1990) Juvenile chronic myelogenous leukemia: differentiation from infantile cytomegalovirus infection, Am. J. Pediatr. Hematol. Oncol. 12, 292-296
    • (1990) Am. J. Pediatr. Hematol. Oncol. , vol.12 , pp. 292-296
    • Kirby, M.A.1    Weitzman, S.2    Freedman, M.H.3
  • 8
    • 0028831774 scopus 로고
    • Clonality in juvenile chronic myelogenous leukemia
    • Busque, L. et al. (1995) Clonality in juvenile chronic myelogenous leukemia, Blood 85, 21-30
    • (1995) Blood , vol.85 , pp. 21-30
    • Busque, L.1
  • 9
    • 0023691225 scopus 로고
    • Interleukin 1-dependent paracrine granulopoiesis in chronic granulocytic leukemia of the juvenile type
    • Bagby, G.C., Jr et al. (1988) Interleukin 1-dependent paracrine granulopoiesis in chronic granulocytic leukemia of the juvenile type, J. Clin. Invest. 82, 143-146
    • (1988) J. Clin. Invest. , vol.82 , pp. 143-146
    • Bagby Jr., G.C.1
  • 10
    • 0026533915 scopus 로고
    • Central role of tumor necrosis factor, GM-CSF, and interleukin 1 in the pathogenesis of juvenile chronic myelogenous leukemia
    • Freedman, M.H. et al. (1992) Central role of tumor necrosis factor, GM-CSF, and interleukin 1 in the pathogenesis of juvenile chronic myelogenous leukemia, Br. J. Haematol. 80, 40-48
    • (1992) Br. J. Haematol. , vol.80 , pp. 40-48
    • Freedman, M.H.1
  • 11
    • 0026006684 scopus 로고
    • The role of monoeyte-derived hemopoietic growth factors in the regulation of myeloproliferation in juvenile chronic myelogenous leukemia
    • Emanuel, P.D. et al. (1991) The role of monoeyte-derived hemopoietic growth factors in the regulation of myeloproliferation in juvenile chronic myelogenous leukemia, Exp. Hematol. 19, 1017-1024
    • (1991) Exp. Hematol. , vol.19 , pp. 1017-1024
    • Emanuel, P.D.1
  • 12
    • 0026063878 scopus 로고
    • Selective hypersensitivity to granulocyte-macrophage colony-stimulating factor by juvenile chronic myeloid leukemia hematopoietic progenitors
    • Emanuel, P.D. et al. (1991) Selective hypersensitivity to granulocyte-macrophage colony-stimulating factor by juvenile chronic myeloid leukemia hematopoietic progenitors, Blood 77, 925-929
    • (1991) Blood , vol.77 , pp. 925-929
    • Emanuel, P.D.1
  • 13
    • 12944270063 scopus 로고
    • + cells in vitro and in vivo using SCID mouse assays
    • + cells in vitro and in vivo using SCID mouse assays, Blood 82 (Suppl. 1), 197a
    • (1993) Blood , vol.82 , Issue.1 SUPPL.
    • Lapidot, T.1
  • 14
    • 4244053499 scopus 로고
    • + purified cells in juvenile and adult chronic myelomonocytic leukemia: Effect of retinoids
    • + purified cells in juvenile and adult chronic myelomonocytic leukemia: effect of retinoids, Blood 86 (Suppl. 1), 791a
    • (1995) Blood , vol.86 , Issue.1 SUPPL.
    • Cambier, N.1
  • 15
    • 0026559506 scopus 로고
    • Transplantation of umbilical cord blood after myeloablative therapy: Analysis of engraftment
    • Wagner, J.E. et al. (1992) Transplantation of umbilical cord blood after myeloablative therapy: analysis of engraftment, Blood 79, 1874-1881
    • (1992) Blood , vol.79 , pp. 1874-1881
    • Wagner, J.E.1
  • 16
    • 0016391236 scopus 로고
    • Bone-marrow responses in polycythemia vera
    • Prchal, J.F. and Axelrad, A.A. (1974) Bone-marrow responses in polycythemia vera, New Engl. J. Med. 290, 1382
    • (1974) New Engl. J. Med. , vol.290 , pp. 1382
    • Prchal, J.F.1    Axelrad, A.A.2
  • 17
    • 0025975727 scopus 로고
    • Polycythemia vera blood burst-forming units-erythroid are hypersensitive to interleukin-3
    • Dai, C.H. et al. (1991) Polycythemia vera blood burst-forming units-erythroid are hypersensitive to interleukin-3, J. Clin. Invest. 87, 391-396
    • (1991) J. Clin. Invest. , vol.87 , pp. 391-396
    • Dai, C.H.1
  • 18
    • 0028045069 scopus 로고
    • Circulating erythroid progenitors in polycythemia vera are hypersensitive to insulin-like growth factor-1 in vitro: Studies in an improved serum-free medium
    • Correa, P.N., Eskinazi, D. and Axelrad, A.A. (1994) Circulating erythroid progenitors in polycythemia vera are hypersensitive to insulin-like growth factor-1 in vitro: studies in an improved serum-free medium, Blood 83, 99-112
    • (1994) Blood , vol.83 , pp. 99-112
    • Correa, P.N.1    Eskinazi, D.2    Axelrad, A.A.3
  • 19
    • 0022217637 scopus 로고
    • Autosomal dominant polycythemia
    • Prchal, J.T. et al. (1985) Autosomal dominant polycythemia, Blood 66, 1208-1214
    • (1985) Blood , vol.66 , pp. 1208-1214
    • Prchal, J.T.1
  • 20
    • 3643117309 scopus 로고
    • Hypersensitivity to hemopoietic growth factors in chronic myelomonocytic leukemia (CMML)
    • Emanuel, P.D., Zhu, S-W., Bates, L.J. and Zuckeiman, K.S. (1991) Hypersensitivity to hemopoietic growth factors in chronic myelomonocytic leukemia (CMML), Blood 78 (Suppl. 1), 156a
    • (1991) Blood , vol.78 , Issue.1 SUPPL.
    • Emanuel, P.D.1    Zhu, S.-W.2    Bates, L.J.3    Zuckeiman, K.S.4
  • 21
    • 0004462338 scopus 로고
    • + cells
    • + cells, Blood 86 (Suppl. 1), 48a
    • (1995) Blood , vol.86 , Issue.1 SUPPL.
    • Li, Y.1
  • 22
    • 8044228496 scopus 로고
    • Inappropriate elevation and loss of feedback regulation of thrombopoietin in essential thrombocythaemia (ET)
    • Taylor, K. et al. (1995) Inappropriate elevation and loss of feedback regulation of thrombopoietin in essential thrombocythaemia (ET), Blood 86 (Suppl. 1), 49a
    • (1995) Blood , vol.86 , Issue.1 SUPPL.
    • Taylor, K.1
  • 23
    • 0027980131 scopus 로고
    • Evolving understanding of the cellular defect in polycythemia vera: Implications for its clinical diagnosis and molecular pathophysiology
    • Prchal, J.T. and Prchal, J.F. (1994) Evolving understanding of the cellular defect in polycythemia vera: implications for its clinical diagnosis and molecular pathophysiology. Blood 83, 1-4
    • (1994) Blood , vol.83 , pp. 1-4
    • Prchal, J.T.1    Prchal, J.F.2
  • 24
    • 0025010979 scopus 로고
    • The GTPase superfamily: A conserved switch for diverse cell functions
    • Bourne, H.R., Sanders, D.A. and McCormick, F. (1990) The GTPase superfamily: a conserved switch for diverse cell functions, Nature 348, 125-132
    • (1990) Nature , vol.348 , pp. 125-132
    • Bourne, H.R.1    Sanders, D.A.2    McCormick, F.3
  • 25
    • 0026345291 scopus 로고
    • Involvement of ras p21 protein in signal transduction pathways from interleukin 2, interleukin 3, and granulocyte/macrophage colony-stimulating factor, but not from interleukin 4
    • Satoh, T., Nakafuku, M, Miyajima, A. and Kaziro, Y. (1991) Involvement of ras p21 protein in signal transduction pathways from interleukin 2, interleukin 3, and granulocyte/macrophage colony-stimulating factor, but not from interleukin 4, Proc. Natl. Acad. Sci. U. S. A. 88, 3314-3318
    • (1991) Proc. Natl. Acad. Sci. U. S. A. , vol.88 , pp. 3314-3318
    • Satoh, T.1    Nakafuku, M.2    Miyajima, A.3    Kaziro, Y.4
  • 26
    • 0024376173 scopus 로고
    • Ras oncogenes in human cancer: A review
    • Bos, J.L. (1989) ras oncogenes in human cancer: a review, Cancer Res. 49, 4682-4689
    • (1989) Cancer Res. , vol.49 , pp. 4682-4689
    • Bos, J.L.1
  • 27
    • 0028344097 scopus 로고
    • Mutations of the N-ras gene in juvenile chronic myelogenous leukemia
    • Miyauchi, J. et al. (1994) Mutations of the N-ras gene in juvenile chronic myelogenous leukemia, Blood 83, 2248-2254
    • (1994) Blood , vol.83 , pp. 2248-2254
    • Miyauchi, J.1
  • 28
    • 0027732538 scopus 로고
    • Proteins regulating Ras and its relatives
    • Boguski, M.S. and McCormick, F. (1993) Proteins regulating Ras and its relatives, Nature 366, 643-654
    • (1993) Nature , vol.366 , pp. 643-654
    • Boguski, M.S.1    McCormick, F.2
  • 29
    • 0017880413 scopus 로고
    • Neurofibromatosis and childhood leukemias
    • Bader, J.L. and Miller, R.W. (1978) Neurofibromatosis and childhood leukemias, J. Pediatr. 92, 925-929
    • (1978) J. Pediatr. , vol.92 , pp. 925-929
    • Bader, J.L.1    Miller, R.W.2
  • 31
    • 0028069689 scopus 로고
    • The NF1 gene in myelopoiesis and childhood myelodys-plastic syndromes
    • Brodeur, G.M. (1994) The NF1 gene in myelopoiesis and childhood myelodys-plastic syndromes, New Engl. J. Med. 330, 637-639
    • (1994) New Engl. J. Med. , vol.330 , pp. 637-639
    • Brodeur, G.M.1
  • 32
    • 0027979146 scopus 로고
    • Loss of the normal NF1 allele from the bone marrow of children with type 1 neurofibromatosis and malignant myeloid disorders
    • Shannon, K.M. et al. (1994) Loss of the normal NF1 allele from the bone marrow of children with type 1 neurofibromatosis and malignant myeloid disorders, New Engl. J. Med. 330, 597-601
    • (1994) New Engl. J. Med. , vol.330 , pp. 597-601
    • Shannon, K.M.1
  • 33
    • 9044251606 scopus 로고    scopus 로고
    • Loss of NF1 results in activation of the Ras signalling pathway and leads to aberrant growth in haematopoietic cells
    • Bollag, G. et al. (1996) Loss of NF1 results in activation of the Ras signalling pathway and leads to aberrant growth in haematopoietic cells, Nat. Genet. 12, 144-148
    • (1996) Nat. Genet. , vol.12 , pp. 144-148
    • Bollag, G.1
  • 34
    • 0030045594 scopus 로고    scopus 로고
    • Nf1 deficiency causes Ras mediated granulocyte/macrophage colony stimulating factor hypersensitivity and chronic myeloid leukemia
    • Largaespada, D.A. et al. (1996) Nf1 deficiency causes Ras mediated granulocyte/macrophage colony stimulating factor hypersensitivity and chronic myeloid leukemia, Nat. Genet. 12, 137-143
    • (1996) Nat. Genet. , vol.12 , pp. 137-143
    • Largaespada, D.A.1
  • 35
    • 0017623968 scopus 로고
    • Treatment of juvenile chronic myeloid leukemia with sequential subcutaneous cytarabine and oral mercaptopurine
    • Lilleyman, J.S., Harrison, J.F. and Black, J.A. (1977) Treatment of juvenile chronic myeloid leukemia with sequential subcutaneous cytarabine and oral mercaptopurine, Blood 49, 559-562
    • (1977) Blood , vol.49 , pp. 559-562
    • Lilleyman, J.S.1    Harrison, J.F.2    Black, J.A.3
  • 36
    • 0023485829 scopus 로고
    • The value of intensive combination chemotherapy for juvenile chronic myelogenous leukemia
    • Chan, H.S., Estrov, Z., Weitzman, S.S. and Freedman, M.H. (1987) The value of intensive combination chemotherapy for juvenile chronic myelogenous leukemia, J Clin. Oncol. 5, 1960-1967
    • (1987) J Clin. Oncol. , vol.5 , pp. 1960-1967
    • Chan, H.S.1    Estrov, Z.2    Weitzman, S.S.3    Freedman, M.H.4
  • 37
    • 0343189651 scopus 로고
    • Allogeneic marrow transplantation for children with juvenile chronic myelogenous leukemia
    • Smith, F.O. et al. (1994) Allogeneic marrow transplantation for children with juvenile chronic myelogenous leukemia, Blood 84 (Suppl. 1), 201a
    • (1994) Blood , vol.84 , Issue.1 SUPPL.
    • Smith, F.O.1
  • 38
    • 0028967873 scopus 로고
    • Pediatric myelodysplasia: A study of 68 children and a new prognostic scoring system
    • Passmore, S.J. et al. (1995) Pediatric myelodysplasia: a study of 68 children and a new prognostic scoring system, Blood 85, 1742-1750
    • (1995) Blood , vol.85 , pp. 1742-1750
    • Passmore, S.J.1
  • 39
    • 0028138595 scopus 로고
    • A pilot study of isoretinoin in the treatment of juvenile chronic myelogenous leukemia
    • Castleberry, R.P. et al. (1994) A pilot study of isoretinoin in the treatment of juvenile chronic myelogenous leukemia, New Engl. J. Med. 331, 1680-1684
    • (1994) New Engl. J. Med. , vol.331 , pp. 1680-1684
    • Castleberry, R.P.1
  • 40
    • 0028331587 scopus 로고
    • Farnesyltransferase inhibitors: Ras research yields a potential cancer therapeutic
    • Gibbs, J.B., Oliff, A. and Kohl, N.B. (1994) Farnesyltransferase inhibitors: Ras research yields a potential cancer therapeutic, Cell 77, 175-178
    • (1994) Cell , vol.77 , pp. 175-178
    • Gibbs, J.B.1    Oliff, A.2    Kohl, N.B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.