Advances in multivariate analysis in pharmaceutical process development

Current Opinion in Drug Discovery and Development

Volumn 6, Issue 6, 2003, Pages 966-977

  McKay, Ben ^a   Hoogenraad, Marcel ^a   Damen, Eric W P ^a   Smith, Alan A ^a  

^a Avantium Technologies BV   (Netherlands)

Author keywords

Chemometrics; Descriptors; High throughput experimentation; Organic process development; Principal component analysis; QSPR; Statistical design of experiments

Indexed keywords

CALANOLIDE A;

ACYLATION; ALGORITHM; ANALYSIS OF VARIANCE; CATALYST; COMPLEX FORMATION; DRUG DESIGN; DRUG INDUSTRY; DRUG MANUFACTURE; DRUG RESEARCH; DRUG SCREENING; FACTORIAL ANALYSIS; HYDROGENATION; ISOMERISM; METHODOLOGY; MULTIVARIATE ANALYSIS; PRINCIPAL COMPONENT ANALYSIS; QUANTITATIVE STRUCTURE ACTIVITY RELATION; REACTION OPTIMIZATION; REVIEW; STATISTICAL ANALYSIS; STEREOCHEMISTRY;

DRUG EVALUATION, PRECLINICAL; MULTIVARIATE ANALYSIS; RESEARCH DESIGN; TECHNOLOGY, PHARMACEUTICAL; TIME FACTORS;

EID: 0347719499     PISSN: 13676733     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

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