Involvement of the nucleotide excision repair proteins in the removal of oxidative DNA base damage in mammalian cells: Minireview

Neoplasma

Volumn 50, Issue 6, 2003, Pages 389-395

  Rybanska I ^a   Pirsel M ^a  

^a INSTITUTE OF CHEMISTRY   (Slovakia)

Author keywords

Base excision repair; Nucleotide excision repair; Oxidative DNA base damage; Reactive oxygen species; Transcription coupled repair

Indexed keywords

DNA BASE; NUCLEOTIDE EXCISION REPAIR PROTEIN; PROTEIN; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

AGING; CARCINOGENESIS; DNA DAMAGE; DNA REPAIR; EXCISION REPAIR; MAMMAL CELL; MUTAGENESIS; OXIDATIVE DNA BASE DAMAGE; OXIDATIVE STRESS; SHORT SURVEY; TRANSCRIPTION COUPLED REPAIR;

EID: 0347518981     PISSN: 00282685     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Short Survey

References (72)

1. AMES BN, GOLD LS, WILLETT WC. The causes and prevention of cancer. Proc Natl Acad Sci USA 1995; 92: 5258-5265.
2. AMES BN, SHIGENAGA MK, HAGEN TM. Oxidants, antioxidants, and the degenerative diseases of a aging. Proc Natl Acad Sci USA 1993; 90: 7915-7922.
3. ARAUJO SJ, TIRODE F, COIN F, POSPIECH H, SYVAOJA JE, STUCKI M, HUBSCHER U, EGLY JM, WOOD RD. Nucleotide excision repair of DNA with recombinant human proteins: definition of the minimal set of factors, active forms of TFIIH, and modulation by CAK. Gene Develop 2000; 14: 349-359.
4. ASPINWALL R, ROTHWELL DG, ROLDANARJONA T, ANSELMINO C, WARD CJ, CHEADLE JP, SAMPSON JR, LINDAHL T, HARRIS PC, HICKSON ID. Cloning and characterization of a functional human homolog of Escherichia coli endonuclease III. Proc Natl Acad Sci USA 1997; 94: 109-114.
5. BARZILAY G, HICKSON ID. Structure and function of apurinic/ apyrimidinic endonucleases. Bioessays 1995; 17: 713-719.
6. BECKMAN KB, AMES BN. Oxidative decay of DNA. J Biol Chem 1997; 272: 19633-19636.
7. BESSHO T. Nucleotide excision repair 3'endonuclease XPG stimulates the activity of base excision repair enzyme thymine glycol DNA glycosylase. Nucl Acid Res 1999; 27: 979-983.
8. BJORAS M, LUNA L, JOHNSON B, HOFF E, HAUG T, ROGNES T, SEEBERG E. Opposite base-dependent reactions of a human base excision repair enzyme on DNA containing 7,8-dihydro-8-oxoguanine and abasic sites. EMBO J 1997; 16: 6314-6322.
9. BOHR VA. Human premature aging syndromes and genomic instability. Mechanisms of Ageing and Development 2002; 123: 987-993.
10. BOITEUX S, LEPAGE F. Repair of 8-oxoguanine and Ogg1-incised apurinic sites in a CHO cell line. In: Moldave K, editor. Progress in Nucleic Acid Research and Molecular Biology, Vol 68. San Diego: Academic Press Inc; 2001. pp 95-105.
11. BRADSHER J, COIN F, EGLY JM. Distinct roles for the helicases of TFIIH in transcript initiation and promoter escape. J Biol Chem 2000; 275: 2532-2538.
12. BROZMANOVA J, DUDAS A, HENRIQUES JAP. Repair of oxidative DNA damage - an important factor reducing cancer risk. Minireview. Neoplasma 2001; 48: 85-93.
13. CASTRO L, FREEMAN B. Reactive oxygen species in human health and disease. Nutrition 2001; 17: 161-165.
14. CHU G, MAYNE L. Xeroderma pigmentosum, Cockayne syndrome and trichothiodystrophy: Do the genes explain the diseases? Trends Genet 1996; 12: 187-192.
15. CITTERIO E, VANDENBOOM V, SCHNITZLER G, KANAAR R, BONTE E, KINGSTON RE, HOEIJMAKERS JHJ, VERMEULEN W. ATP-dependent chromatin remodeling by the Cockayne syndrome B DNA repair-transcription-coupling factor. Mol Cell Biol 2000; 20: 7643-7653.
16. COLLINS AR, HORVATHOVA E. Oxidative DNA damage, antioxidants and DNA repair: applications of the comet assay. Biochem Soc Trans 2001; 29: 337-341.
17. COOPER PK, NOUSPIKEL T, CLARKSON SG, LEADON SA. Defective transcription-coupled repair of oxidative base damage in Cockayne syndrome patients from XP group G. Science 1997; 275: 990-993.
18. DEMPLE B, HARRISON L. Repair of oxidative damage to DNA: Enzymology and biology. Annu Rev Biochem 1994; 63915-63948.
19. DIZDAROGLU M, KARAHALIL B, SENTURKER S, BUCKLEY TJ, ROLDANARJONA T. Excision of products of oxidative DNA base damage by human NTH1 protein. Biochemistry USA 1999; 38: 243-246.
20. DOETSCH PW, CUNNINGHAM RP. The enzymology of apurinic/ apyrimidinic endonucleases. Mutation Res 1990; 236: 173-201.
21. DOETSCH PW, MOREY NJ, SWANSON RL, JINKSROBERTSON S. Yeast base excision repair: Interconnections and networks. In: Moldave K, editor. Progress in Nucleic Acid Research and Molecular Biology, Vol 68. San Diego: Academic Press Inc; 2001. pp 29-39.
22. EVANS AR, LIMPFOSTER M, KELLEY MR. Going APE over ref-1. Mutat Res DNA Repair 2000; 461: 83-108.
23. EVANS E, FELLOWS J, COFFER A, WOOD RD. Open complex formation around a lesion during nucleotide excision repair provides a structure for cleavage by human XPG protein. EMBO J 1997; 16: 625-638.
24. FRIEDBERG EC, MEIRA LB. Database of mouse strains carrying targeted mutations in genes affecting biological responses to DNA damage. Version 5. DNA Repair (Amst) 2003; 2: 501-530.
25. FROSINA G. Overexpression of enzymes that repair endogenous damage to DNA. Eur J Biochem 2000; 267: 2135-2149.
26. FROSINA G, FORTINI P, ROSSI O, CARROZZINO F, RASPAGLIO G, COX LS, LANE DP, ABBONDANDOLO A, DOGLIOTTI E. Two pathways for base excision repair in mammalian cells. J Biol Chem 1996; 271: 9573-9578.
27. GELLON L, BARBEY R, VAN DER KEMP PA, THOMAS D, BOITEUX S. Synergism between base excision repair, mediated by the DNA glycosylases Ntg1 and Ntg2, and nucleotide excision repair in the removal of oxidatively damaged DNA bases in Saccharomyces cerevisiae. Mol Genet Genomics 2001; 265: 1087-1096.
28. GRACY RW, TALENT JM, KONG Y, CONRAD CC. Reactive oxygen species: the unavoidable environmental insult? Mutat Res Fundam Mol Mech Mut 1999; 428: 17-22.
29. HAZRA TK, IZUMI T, BOLDOGH I, IMHOFF B, Kow YW, JARUGA P, DIZDAROGLU M, METRA S. Identification and characterization of a human DNA glycosylase for repair of modified bases in oxidatively damaged DNA. Proceedings of the National Academy of Sciences of the United States of America 2002; 99: 3523-3528.
30. HAZRA TK, KOW YW, HATAHET Z, IMHOFF B, BOLDOGH I, MOKKAPATI SK, MITRA S, IZUMI T. Identification and characterization of a novel human DNA glycosylase for repair of cytosine-derived lesions. J Biol Chem 2002; 277: 30417-30420.
31. HENNING KA, LI L, IYER N, MCDANIEL LD, REAGAN MS, LEGERSKI R, SCHULTZ RA, STEFANINI M, LEHMANN AR, MAYNE LV, FRIEDBERG EC. The Cockayne syndrome group A gene encodes a WD repeat protein that interacts with CSB protein and a subunit of RNA polymerase II TFIIH. Cell 1995; 82: 555-564.
32. IYER N, REAGAN MS, Wu KJ, CANAGARAJAH B, FRIEDBERG EC. Interactions involving the human RNA polymerase II transcription/nucleotide excision repair complex TFIIH, the nucleotide excision repair protein XPG, and Cockayne syndrome group B (CSB) protein. Biochemistry 1996; 35: 2157-2167.
33. KLUNGLAND A, LINDAHLT. Second pathway for completion of human DNA base excision-repair: Reconstitution with purified proteins and requirement for DNase IV (FEN1). EMBO J 1997; 16: 3341-3348.
34. KLUNGLAND A, ROSEWELL I, HOLLENBACH S, LARSEN E, DALY G, EPE B, SEEBERG E, LINDAHL T, BARNES DE. Accumulation of premutagenic DNA lesions in mice defective in removal of oxidative base damage. Proc Natl Acad Sci USA 1999; 96: 13300-13305.
35. KOW YW, WALLACE SS, VAN HOUTEN B. UvrABC nuclease complex repairs thymine glycol, an oxidative DNA base damage. Mutat Res 1990; 235: 147-156.
36. KROKAN HE, STANDAL R, SLUPPHAUG G. DNA glycosylases in the base excision repair of DNA. Biochem J 1997; 325: 1-16.
37. LEADON SA. Transcription-coupled repair: A multifunctional signaling pathway. Cold Spring Harbor Symp 2000; 65: 561-566.
38. LEADON SA, COOPER PK. Preferential repair of ionizing radiation-induced damage in the transcribed strand of an active human gene is defective in Cockayne syndrome. Proc Natl Acad Sci USA 1993; 90: 10499-10503.
39. LEPAGE F, KLUNGLAND A, BARNES DE, SARASIN A, BOITEUX S. Transcription coupled repair of 8-oxoguanine in murine cells: The Ogg1 protein is required for repair in nontranscribed sequences but not in transcribed sequences. Proc Natl Acad Sci USA 2000; 97: 8397-8402.
40. LEPAGE F, KWOH EE, AVRUTSKAYA A, GENTIL A, LEADON SA, SARASIN A, COOPER PK. Transcription-coupled repair of 8-oxoGuanine: Requirement for XPG, TFIIH, and CSB and implications for Cockayne syndrome. Cell 2000; 101: 159-171.
41. LEPAGE F, RANDRIANARISON V, MAROT D, CABANNES J, PERRICAUDET M, FEUNTEUN J, SARASIN A. BRCA1 and BRCA2 are necessary for the transcription-coupled repair of the oxidative 8-oxoguanine lesion in human cells. Cancer Res 2000; 60: 5548-5552.
42. LIN JJ, SANCAR A. A new mechanism for repairing oxidative damage to DNA: (A)BC excinuclease removes AP sites and Thymine Glycols from DNA. Biochemistry 1989; 28: 7979-7984.
43. MATSUMOTO Y, Kim K. Excision of deoxyribose phosphate residues by DNA polymerase beta during DNA repair. Science 1995; 269: 699-702.
44. MELLON I, SPIVAK G, HANAWALT PC. Selective removal of transcription-blocking DNA damage from the transcribed strand of the mammalian DHFR gene. Cell 1987; 51: 241-249.
45. MINOWA O, ARAI T, HIRANO M, MONDEN Y, NAKAI S, FUKUDA M, ITOH M, TAKANO H, HIPPOU Y, ABURATANI H, MASUMURA K, NOHMI T, NISHIMURA S, NODA T. Mmh/Ogg1 gene inactivation results in accumulation of 8-hydroxyguanine in mice. Proc Natl Acad Sci USAsa 2000; 97: 4156-4161.
46. MITRA S, HAZRA TK, ROY R, IKEDA S, BISWAS T, LOCK J, BOLDOGH I, IZUMI T. Complexities of DNA base excision repair in mammalian cells. Mol Cells 1997; 7: 305-312.
47. MOLLER P, WALLIN H. Adduct formation, mutagenesis and nucleotide excision repair of DNA damage produced by reactive oxygen species and lipid peroxidation product. Mutat Res-Rev Mutat Res 1998; 410: 271-290.
48. MU D, HSU DS, SANCAR A. Reaction mechanism of human DNA repair excision nuclease. J Biol Chem 1996; 271: 8285-8294.
49. MU D, SANCAR A. Model for XPC-independent transcription-coupled repair of pyrimidine dimers in humans. J Biol Chem 1997; 272: 7570-7573.
50. NILSEN H, KROKAN HE. Base excision repair in a network of defence and tolerance. Carcinogenesis 2001; 22: 987-998.
51. PARK E, GUZDER SN, KOKEN MHM, JASPERSDEKKER I, WEEDA G, HOEIJMAKERS JHJ, PRAKASH S, PRAKASH L. RAD25 (SSL2), the yeast homolog of the human Xeroderma-pigmentosum group-B DNA repair gene, is essential for viability. Proc Natl Acad Sci USA 1992; 89: 11416-11420.
52. PIERSEN CE, PRASAD R, WILSON SH, LLOYD RS. Evidence for an imino intermediate in the DNA polymerase beta deoxyribose phosphate excision reaction. J Biol Chemistry 1996; 271: 17811-17815.
53. PRASAD R, BEARD WA, STRAUSS PR, WILSON SH. Human DNA polymerase beta deoxyribose phosphate lyase - substrate specificity and catalytic mechanism. J Biol Chem 1998; 273: 15263-15270.
54. RAHMAN I, MACNEE W. Role of oxidants/antioxidants in smoking-induced lung diseases. Free Radic Biol Med 1996; 21: 669-681.
55. REARDON JT, BESSHO T, KUNG HC, BOLTON PH, SANCAR A. In vitro repair of oxidative DNA damage by human nucleotide excision repair system: Possible explanation for neurodegeneration in Xeroderma pigmentosum patients. Proc Natl Acad Sci USA 1997; 94: 9463-9468.
56. RILEY PA. Free radicals in biology - oxidative stress and the effects of ionizing radiation. Int J Radiat Biol 1994; 65: 27-33.
57. SCHAEFFER L, ROY R, HUMBERT S, MONCOLLIN V, VERMEULEN W, HOEIJMAKERS JHJ, CHAMBON P, EGLY JM. DNA repair helicase - A component of BTF2 (TFIIH) basic transcription factor. Science 1993; 260: 58-63.
58. SELBY CP, SANCAR A. Human transcription-repair coupling factor CSB/ERCC6 is a DNA-stimulated ATPase but is not a helicase and does not disrupt the ternary transcription complex of stalled RNA polymerase II. J Biol Chem 1997; 272: 1885-1890.
59. SHINMURA A, YAMAGUCHI S, SAITOH T, TAKEUCHI SASAKI M, KIM SR, NOHMI T, YOKOTA J. Adenine excisional repair function of MYH protein on the adenine: 8-hydroxyguanine base pair in double-stranded DNA. Nucl Acid Res 2000; 28: 4912-4918.
60. SUBERS AM, DELAAT WL, ARIZA RR, BIGGERSTAFF M, WEI YF, MOGGS JG, CARTER KC, SHELL BK, EVANS E, DEJONG MC, RADEMAKERS S, DEROOIJ J, JASPERS NGJ, HOEIJMAKERS JHJ, WOOD RD. Xeroderma pigmentosum group F caused by a defect in a structure-specific DNA repair endonuclease. Cell 1996; 86: 811-822.
61. SINGHAL RK, PRASAD R, WILSON SH. DNA polymerase beta conducts the gap-filling step in uracil-initiated base excision repair in a bovine testis nuclear extract. J Biol Chem 1995; 270: 949-957.
62. SOHAL RS, MOCKETT RJ, ORR WC. Mechanisms of aging: An appraisal of the oxidative stress hypothesis. Free Radical Biology and Medicine 2002; 33: 575-586.
63. SRIVASTAVA DK, VANDEBERG BJ, PRASAD R, MOLINA JT, BEARD WA, TOMKINSON AE, WILSON SH. Mammalian abasic site base excision repair - Identification of the reaction sequence and rate-determining steps. J Biol Chem 1998; 273: 21203-21209.
64. SUGASAWA K, NG JMY, MASUTANI C, IWAI S, VANDERSPEK PJ, EKER APM, HANAOKA F, BOOTSMA D, HOEIJMAKERS JHJ. Xeroderma pigmentosum group C protein complex is the initiator of global genome nucleotide excision repair. Mol Cell 1998; 2: 223-232.
65. SUNESEN M, STEVNSNER T, BROSH RM, DIANOV GL, BOHR VA. Global genome repair of 8-oxoG in hamster cells requires a functional CSB gene product. Oncogene 2002; 21: 3571-3578.
66. SWANSON RL, MOREY NJ, DOETSCH PW, JINKSROBERTSON S. Overlapping specificities of base excision repair, nucleotide excision repair, recombination, and translesion synthesis pathways for DNA base damage in Saccharomyces cerevisiae. Mol Cell Biol 1999; 19: 2929-2935.
67. TAKAO M, KANNO S, SHIROMOTO T, HASEGAWA R, IDE H, IKEDA S, SARKER AH, SEKI S, XING JZ, LE XC, WEINFELD M, KOBAYASHI K, MIYAZAKI J, MUIJTJENS M, HOEIJMAKERS JHJ, VAN DER HORST G, YASUI A. Novel nuclear and mitochondrial glycosylases revealed by disruption of the mouse Nth1 gene encoding an endonuclease III homolog for repair of thymine glycols. EMBO J 2002; 21: 3486-3493.
68. TANTIN D. RNA polymerase II elongation complexes containing the cockayne syndrome group B protein interact with a molecular complex containing the transcription factor IIH components xeroderma pigmentosum B and p62. J Biol Chem 1998; 273: 27794-27799.
69. THORSLUND T, SUNESEN M, BOHR VA, STEVNSNER T. Repair of 8-oxoG is slower in endogenous nuclear genes than in mitochondrial DNA and is without strand bias. DNA Repair (Amst) 2002; 1: 261-273.
70. WAKASUGI M, KAWASHIMA A, MORIOKA H, LINN S, SANCAR A, MORI T, NIKAIDO O, MATSUNAGA T. DDB accumulates at DNA damage sites immediately after UV irradiation and directly stimulates nucleotide excision repair. J Biol Chem 2002; 277: 1637-1640.
71. WALLACE SS. Biological consequences of free radical-damaged DNA bases. Free Radical Biology and Medicine 2002; 33: 1-14.
72. WANG D, KREUTZER DA, ESSIGMANN JM. Mutagenicity and repair of oxidative DNA damage: insights from studies using defined lesions. Mutat Res-Fundam Mol Mech Mut 1998; 400: 99-115.