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Volumn 14, Issue 18, 2003, Pages 1787-1798

Retroviral Immunotoxin Gene Therapy of Leukemia in Mice Using Leukemia-Specific T Cells Transduced with an Interleukin-3/Bax Fusion Protein Gene

Author keywords

[No Author keywords available]

Indexed keywords

DIPHTHERIA TOXIN; IMMUNOTOXIN; INTERLEUKIN 3; PROTEIN BAX; PROTEIN BCL 2; PSEUDOMONAS EXOTOXIN;

EID: 0347517727     PISSN: 10430342     EISSN: None     Source Type: Journal    
DOI: 10.1089/104303403322611791     Document Type: Article
Times cited : (9)

References (50)
  • 1
    • 0032575688 scopus 로고    scopus 로고
    • The Bcl-2 protein family: Arbiters of cell survival
    • ADAMS, J.M., and CORY, S. (1998), The Bcl-2 protein family: Arbiters of cell survival. Science 281, 1322-1326.
    • (1998) Science , vol.281 , pp. 1322-1326
    • Adams, J.M.1    Cory, S.2
  • 3
    • 0032779831 scopus 로고    scopus 로고
    • Interleukin 2-Bax: A novel prototype of human chimeric proteins for targeted therapy
    • AQEILAN, R., YARKONI, S., and LORBERBOUM-GALSKI, H. (1999). Interleukin 2-Bax: A novel prototype of human chimeric proteins for targeted therapy. FEBS Lett. 457, 271-276.
    • (1999) FEBS Lett. , vol.457 , pp. 271-276
    • Aqeilan, R.1    Yarkoni, S.2    Lorberboum-Galski, H.3
  • 7
    • 0031053758 scopus 로고    scopus 로고
    • Killing mechanisms of cytotoxic lymphocytes
    • BERKE, G. (1997). Killing mechanisms of cytotoxic lymphocytes. Curr. Opin. Hematol. 4, 32-40.
    • (1997) Curr. Opin. Hematol. , vol.4 , pp. 32-40
    • Berke, G.1
  • 8
    • 0037262225 scopus 로고    scopus 로고
    • Diphtheria toxin-interleukin-3 fusion protein (DT(388)IL-3) prolongs disease-free survival of leukemic immunocompromised mice
    • BLACK, J.H., MCCUBREY, J.A., WILLINGHAM, M.C., RAMAGE, J., HOGGE, D.E., and FRANKEL, A.E. (2003). Diphtheria toxin-interleukin-3 fusion protein (DT(388)IL-3) prolongs disease-free survival of leukemic immunocompromised mice. Leukemia 17, 155-159.
    • (2003) Leukemia , vol.17 , pp. 155-159
    • Black, J.H.1    Mccubrey, J.A.2    Willingham, M.C.3    Ramage, J.4    Hogge, D.E.5    Frankel, A.E.6
  • 9
    • 0343865682 scopus 로고
    • Myloid leukemia C1498 as a screen for cancer chemotherapeutic agents
    • BRADNER, W.T., and PINDELL, M.H. (1966). Myloid leukemia C1498 as a screen for cancer chemotherapeutic agents. Cancer Chemother. Screening Data 43, 375-390.
    • (1966) Cancer Chemother. Screening Data , vol.43 , pp. 375-390
    • Bradner, W.T.1    Pindell, M.H.2
  • 10
    • 0029838673 scopus 로고    scopus 로고
    • Reactivity of murine cytokine fusion toxin, diphtheria toxin390-murine interleukin-3 (DT390-mIL-3), with bone marrow progenitor cells
    • CHAN, C.H., BLAZAR, B.R., GREENFIELD, L., KREITMAN, R.J., and VALLERA, D.A. (1996). Reactivity of murine cytokine fusion toxin, diphtheria toxin390-murine interleukin-3 (DT390-mIL-3), with bone marrow progenitor cells. Blood 88, 1445-1456.
    • (1996) Blood , vol.88 , pp. 1445-1456
    • Chan, C.H.1    Blazar, B.R.2    Greenfield, L.3    Kreitman, R.J.4    Vallera, D.A.5
  • 11
    • 0030763687 scopus 로고    scopus 로고
    • Therapy with cultured T cells: Principles revisited
    • CHEEVER, M.A., and CHEN, W. (1997). Therapy with cultured T cells: Principles revisited. Immunol. Rev. 157, 177-194.
    • (1997) Immunol. Rev. , vol.157 , pp. 177-194
    • Cheever, M.A.1    Chen, W.2
  • 12
    • 0028922605 scopus 로고
    • Design of a genetic immunotoxin to eliminate toxin immunogenicity
    • CHEN, S.Y., ZANI, C., KHOURI, Y., and MARASCO, W.A. (1995). Design of a genetic immunotoxin to eliminate toxin immunogenicity. Gene Ther. 2, 116-123.
    • (1995) Gene Ther. , vol.2 , pp. 116-123
    • Chen, S.Y.1    Zani, C.2    Khouri, Y.3    Marasco, W.A.4
  • 14
    • 0025293113 scopus 로고
    • Adoptively transferred antigen-specific T cells can be grown and maintained in large numbers in vivo for extended periods of time by intermittent restimulation with specific antigen plus IL-2
    • CHEN, W., REESE, V.A., and CHEEVER, M.A. (1990). Adoptively transferred antigen-specific T cells can be grown and maintained in large numbers in vivo for extended periods of time by intermittent restimulation with specific antigen plus IL-2. J. Immunol. 144, 3659-3666.
    • (1990) J. Immunol. , vol.144 , pp. 3659-3666
    • Chen, W.1    Reese, V.A.2    Cheever, M.A.3
  • 16
    • 0016609883 scopus 로고
    • Diphtheria toxin: Mode of action and structure
    • COLLIER, R.J. (1975). Diphtheria toxin: Mode of action and structure. Bacteriol. Rev. 39, 54-85.
    • (1975) Bacteriol. Rev. , vol.39 , pp. 54-85
    • Collier, R.J.1
  • 18
    • 0000140269 scopus 로고
    • A survey of transplantable and transmissible animal tumors
    • DURHAM, L.J., and STEWART, H.L. (1953). A survey of transplantable and transmissible animal tumors. J. Natl. Cancer Inst. 13, 1299-1377.
    • (1953) J. Natl. Cancer Inst. , vol.13 , pp. 1299-1377
    • Durham, L.J.1    Stewart, H.L.2
  • 19
    • 0037085927 scopus 로고    scopus 로고
    • A diphtheria toxin-interleukin 3 fusion protein is cytotoxic to primitive acute myeloid leukemia progenitors but spares normal progenitors
    • FEURING-BUSKE M., FRANKEL A.E., ALEXANDER R.L., GERHARD B., and HOGGE D.E. (2002). A diphtheria toxin-interleukin 3 fusion protein is cytotoxic to primitive acute myeloid leukemia progenitors but spares normal progenitors. Cancer Res. 62, 1730-1736.
    • (2002) Cancer Res. , vol.62 , pp. 1730-1736
    • Feuring-Buske, M.1    Frankel, A.E.2    Alexander, R.L.3    Gerhard, B.4    Hogge, D.E.5
  • 20
    • 0028017569 scopus 로고
    • Chimeric fusion protein toxin DAB486IL-2 in advanced mycosis fungoides and the Sezary syndrome: Correlation of activity and interleukin-2 receptor expression in a phase II study
    • FOSS, F.M., BORKOWSKI, T.A., GILLIOM, M., STETLER-STEVENSON, M., JAFFE, E.S., FIGG, W.D., TOMPKINS, A., BASTIAN, A., NYLEN, P., WOODWORTH, T., et al. (1994). Chimeric fusion protein toxin DAB486IL-2 in advanced mycosis fungoides and the Sezary syndrome: Correlation of activity and interleukin-2 receptor expression in a phase II study. Blood 84, 1765-1774.
    • (1994) Blood , vol.84 , pp. 1765-1774
    • Foss, F.M.1    Borkowski, T.A.2    Gilliom, M.3    Stetler-Stevenson, M.4    Jaffe, E.S.5    Figg, W.D.6    Tompkins, A.7    Bastian, A.8    Nylen, P.9    Woodworth, T.10
  • 21
    • 0032528118 scopus 로고    scopus 로고
    • Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis
    • GROSS, A., JOCKEL J., WEI, M.C., and KORSMEYER, S.J. (1998). Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis. EMBO J. 17, 3878-3885.
    • (1998) EMBO J. , vol.17 , pp. 3878-3885
    • Gross, A.1    Jockel, J.2    Wei, M.C.3    Korsmeyer, S.J.4
  • 22
    • 0028868260 scopus 로고
    • The tumor suppressor protein p53: A receptor to genotoxic stress that controls cell growth and survival
    • HAINAUT, P. (1995). The tumor suppressor protein p53: A receptor to genotoxic stress that controls cell growth and survival. Curr. Opin. Oncol. 7, 76-82.
    • (1995) Curr. Opin. Oncol. , vol.7 , pp. 76-82
    • Hainaut, P.1
  • 23
    • 0014429772 scopus 로고
    • Diphtheria toxin-dependent adenosine diphosphate ribosylation of aminoacyl transferase II and inhibition of protein synthesis
    • HONJO, T., NISHIZUKA, Y., and HATAISHI, O. (1968). Diphtheria toxin-dependent adenosine diphosphate ribosylation of aminoacyl transferase II and inhibition of protein synthesis. J. Biol. Chem. 243, 3553-3555.
    • (1968) J. Biol. Chem. , vol.243 , pp. 3553-3555
    • Honjo, T.1    Nishizuka, Y.2    Hataishi, O.3
  • 24
    • 0030963602 scopus 로고    scopus 로고
    • Cytosol-to-membrane redistribution of Bax and Bcl-X(L) during apoptosis
    • HSU, Y.T., WOLTER, K.G., and YOULE, R.J. (1997). Cytosol-to-membrane redistribution of Bax and Bcl-X(L) during apoptosis. Proc. Natl. Acad. Sci. U.S.A. 94, 3668-3672.
    • (1997) Proc. Natl. Acad. Sci. U.S.A. , vol.94 , pp. 3668-3672
    • Hsu, Y.T.1    Wolter, K.G.2    Youle, R.J.3
  • 25
    • 0036494705 scopus 로고    scopus 로고
    • Extracellular Bad fused to toxin transport domains induces apoptosis
    • ICHINOSE, M., LIU, X.H., HAGIHARA, N., and YOULE, R.J. (2002). Extracellular Bad fused to toxin transport domains induces apoptosis. Cancer Res. 62, 1433-1438.
    • (2002) Cancer Res. , vol.62 , pp. 1433-1438
    • Ichinose, M.1    Liu, X.H.2    Hagihara, N.3    Youle, R.J.4
  • 26
    • 0030947095 scopus 로고    scopus 로고
    • Programmed cell death in animal development
    • JACOBSON, M.D., WEIL, M., and RAFF, M.C. (1997). Programmed cell death in animal development. Cell 88, 347-354.
    • (1997) Cell , vol.88 , pp. 347-354
    • Jacobson, M.D.1    Weil, M.2    Raff, M.C.3
  • 27
    • 0036204508 scopus 로고    scopus 로고
    • Gene therapy of murine solid tumors with T cells transduced with a retroviral vascular endothelial growth factor-immunotoxin target gene
    • JIN, N., CHEN, W., BLAZAR, B.R., RAMAKRISHNAN, S., and VALLERA, D.A. (2002). Gene therapy of murine solid tumors with T cells transduced with a retroviral vascular endothelial growth factor-immunotoxin target gene. Hum. Gene Ther. 13, 497-508.
    • (2002) Hum. Gene Ther. , vol.13 , pp. 497-508
    • Jin, N.1    Chen, W.2    Blazar, B.R.3    Ramakrishnan, S.4    Vallera, D.A.5
  • 28
    • 0019819794 scopus 로고
    • Diphtheria toxin fragment forms large pores in phospholipid bilayer membranes
    • KAGAN, B.L., FINKELSTEIN, A., and COLOMBINI, M. (1981). Diphtheria toxin fragment forms large pores in phospholipid bilayer membranes. Proc. Natl. Acad. Sci. U.S.A. 78, 4950-4954.
    • (1981) Proc. Natl. Acad. Sci. U.S.A. , vol.78 , pp. 4950-4954
    • Kagan, B.L.1    Finkelstein, A.2    Colombini, M.3
  • 29
    • 0036268469 scopus 로고    scopus 로고
    • Targeting glioblastoma multiforme with an IL-13/diphtheria toxin fusion protein in vitro and in vivo in nude mice
    • LI, C., HALL, W.A., JIN, N., TODHUNTER, D.A., PANOSKALTSIS-MORTARI, A., and VALLERA, D.A. (2002). Targeting glioblastoma multiforme with an IL-13/diphtheria toxin fusion protein in vitro and in vivo in nude mice. Protein Eng. 15, 419-427.
    • (2002) Protein Eng. , vol.15 , pp. 419-427
    • Li, C.1    Hall, W.A.2    Jin, N.3    Todhunter, D.A.4    Panoskaltsis-Mortari, A.5    Vallera, D.A.6
  • 30
    • 0036073839 scopus 로고    scopus 로고
    • Making room for T cells
    • MAINE, G.N., and MULE, J.J. (2002). Making room for T cells. J. Clin. Invest. 110, 185-192.
    • (2002) J. Clin. Invest. , vol.110 , pp. 185-192
    • Maine, G.N.1    Mule, J.J.2
  • 32
    • 0029383734 scopus 로고
    • Targeting diphtheria toxin to growth factor receptors
    • MURPHY, J.R., and VANDERSPEK, J.C. (1995). Targeting diphtheria toxin to growth factor receptors. Semin. Cancer Biol. 6, 259-267.
    • (1995) Semin. Cancer Biol. , vol.6 , pp. 259-267
    • Murphy, J.R.1    Vanderspek, J.C.2
  • 33
    • 0027166048 scopus 로고
    • Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death
    • OLTVAI, Z.N., MILLIMAN, C.L., and KORSMEYER, S.J. (1993). Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell 74, 609-619.
    • (1993) Cell , vol.74 , pp. 609-619
    • Oltvai, Z.N.1    Milliman, C.L.2    Korsmeyer, S.J.3
  • 34
    • 0031782910 scopus 로고    scopus 로고
    • The role of CD4+ T cell responses in antitumor immunity
    • PARDOLL, D., and TOPALIAN, S.L. (1998). The role of CD4+ T cell responses in antitumor immunity. Curr. Opin. Immunol. 10, 588-594.
    • (1998) Curr. Opin. Immunol. , vol.10 , pp. 588-594
    • Pardoll, D.1    Topalian, S.L.2
  • 35
    • 0030222331 scopus 로고    scopus 로고
    • Approaching the mechanism of protein transport across the ER membrane
    • RAPOPORT, T.A., ROLLS, M., and JUNGNICKEL, B. (1996). Approaching the mechanism of protein transport across the ER membrane. Curr. Opin. Cell Biol. 8, 499-504.
    • (1996) Curr. Opin. Cell Biol. , vol.8 , pp. 499-504
    • Rapoport, T.A.1    Rolls, M.2    Jungnickel, B.3
  • 36
    • 0029150110 scopus 로고
    • Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
    • SAKAGUCHI S., SAKAGUCHI, N., ASANO, M., ITOH, M., and TODA, M. (1995). Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J. Immunol. 155, 1151-1164.
    • (1995) J. Immunol. , vol.155 , pp. 1151-1164
    • Sakaguchi, S.1    Sakaguchi, N.2    Asano, M.3    Itoh, M.4    Toda, M.5
  • 38
    • 0033767685 scopus 로고    scopus 로고
    • Adenovirus-mediated transfer of Fas ligand gene augments radiation-induced apoptosis in U-373MG glioma cells
    • SHINOURA, N., YAMAMOTO, N., ASAI, A., KIRINO, T., and HAMADA, H. (2000) Adenovirus-mediated transfer of Fas ligand gene augments radiation-induced apoptosis in U-373MG glioma cells. Jpn. J. Cancer. Res. 91, 1044-1050.
    • (2000) Jpn. J. Cancer. Res. , vol.91 , pp. 1044-1050
    • Shinoura, N.1    Yamamoto, N.2    Asai, A.3    Kirino, T.4    Hamada, H.5
  • 39
    • 0031939403 scopus 로고    scopus 로고
    • CD4+CD25+ T cells inhibit both the induction and effector function of autoreactive T cells and represent a unique lineage of immunoregulatory cells
    • SURI-PAYER, E., AMAR, A.Z., THORNTON, A.M., and SHEVACH, E.M. (1998). CD4+CD25+ T cells inhibit both the induction and effector function of autoreactive T cells and represent a unique lineage of immunoregulatory cells. J. Immunol. 160, 1212-1218.
    • (1998) J. Immunol. , vol.160 , pp. 1212-1218
    • Suri-Payer, E.1    Amar, A.Z.2    Thornton, A.M.3    Shevach, E.M.4
  • 41
    • 0032821010 scopus 로고    scopus 로고
    • Targeting myeloid leukemia with a DT(390)-mIL-3 fusion immunotoxin: Ex vivo and in vivo studies in mice
    • VALLERA, D.A., SEO, S.Y., PANOSKALTSIS-MORTARI, A., GRIFFIN, J.D., and BLAZAR, B.R. (1999). Targeting myeloid leukemia with a DT(390)-mIL-3 fusion immunotoxin: Ex vivo and in vivo studies in mice. Protein Eng. 12, 779-785.
    • (1999) Protein Eng. , vol.12 , pp. 779-785
    • Vallera, D.A.1    Seo, S.Y.2    Panoskaltsis-Mortari, A.3    Griffin, J.D.4    Blazar, B.R.5
  • 42
    • 0034652579 scopus 로고    scopus 로고
    • Retroviral immunotoxin gene therapy of acute myelogenous leukemia in mice using cytotoxic T cells transduced with an interleukin 4/diphtheria toxin gene
    • VALLERA, D.A., JIN, N., BALDRICA, J.M., PANOSKALTSIS-MORTARI, A., CHEN, S.Y., and BLAZAR, B.R. (2000). Retroviral immunotoxin gene therapy of acute myelogenous leukemia in mice using cytotoxic T cells transduced with an interleukin 4/diphtheria toxin gene. Cancer Res. 60, 976-984.
    • (2000) Cancer Res. , vol.60 , pp. 976-984
    • Vallera, D.A.1    Jin, N.2    Baldrica, J.M.3    Panoskaltsis-Mortari, A.4    Chen, S.Y.5    Blazar, B.R.6
  • 43
    • 0037123350 scopus 로고    scopus 로고
    • Targeting urokinase-type plasminogen activator receptor on human glioblastoma tumors with diphtheria toxin fusion protein DTAT
    • VALLERA, D.A., LI, C., JIN, N., PANOSKALTSIS-MORTARI, A., and HALL, W.A. (2002). Targeting urokinase-type plasminogen activator receptor on human glioblastoma tumors with diphtheria toxin fusion protein DTAT. J. Natl. Cancer Inst. 94, 597-606.
    • (2002) J. Natl. Cancer Inst. , vol.94 , pp. 597-606
    • Vallera, D.A.1    Li, C.2    Jin, N.3    Panoskaltsis-Mortari, A.4    Hall, W.A.5
  • 44
    • 0028326952 scopus 로고
    • An evolutionary perspective on apoptosis
    • VAUX, D.L., HEACKER, G., and STRASSER, A. (1994). An evolutionary perspective on apoptosis. Cell 76, 777-779.
    • (1994) Cell , vol.76 , pp. 777-779
    • Vaux, D.L.1    Heacker, G.2    Strasser, A.3
  • 45
    • 0028170807 scopus 로고
    • Signal sequence recognition and protein targeting to the endoplasmic reticulum membrane
    • WALTER, P., and JOHNSON, A.E. (1994). Signal sequence recognition and protein targeting to the endoplasmic reticulum membrane. Annu. Rev. Cell Biol. 10, 87-119.
    • (1994) Annu. Rev. Cell Biol. , vol.10 , pp. 87-119
    • Walter, P.1    Johnson, A.E.2
  • 46
    • 0032533837 scopus 로고    scopus 로고
    • Eliciting T cell immunity against poorly immunogenic tumors by immunization with dendritic cell-tumor fusion vaccines
    • WANG, J., SAFFOLD, S., CAO, X., KRAUSS, J., and CHEN, W. (1998). Eliciting T cell immunity against poorly immunogenic tumors by immunization with dendritic cell-tumor fusion vaccines. J. Immunol. 161, 5516-5524.
    • (1998) J. Immunol. , vol.161 , pp. 5516-5524
    • Wang, J.1    Saffold, S.2    Cao, X.3    Krauss, J.4    Chen, W.5
  • 49
    • 0028908353 scopus 로고
    • Interaction of the isolated transmembrane domain of diphtheria toxin with membranes
    • ZHAN, H., OH, K.J., SHIN, Y.K., HUBBELL, W.L., and COLLIER, R.J. (1995). Interaction of the isolated transmembrane domain of diphtheria toxin with membranes. Biochemistry 34, 4856-4863.
    • (1995) Biochemistry , vol.34 , pp. 4856-4863
    • Zhan, H.1    Oh, K.J.2    Shin, Y.K.3    Hubbell, W.L.4    Collier, R.J.5
  • 50
    • 0036099858 scopus 로고    scopus 로고
    • Preterminal host dendritic cells in irradiated mice prime CD8+ T cell-mediated acute graft-versus-host disease
    • ZHANG, Y., LOUBOUTIN, J.P., ZHU, J., RIVERA, A.J., and EMERSON, S.G. (2002). Preterminal host dendritic cells in irradiated mice prime CD8+ T cell-mediated acute graft-versus-host disease. J. Clin. Invest. 109, 1335-1344.
    • (2002) J. Clin. Invest. , vol.109 , pp. 1335-1344
    • Zhang, Y.1    Louboutin, J.P.2    Zhu, J.3    Rivera, A.J.4    Emerson, S.G.5


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