Selective prion protein binding to synaptic components is modulated by oxidative and nitrosative changes induced by copper(II) and peroxynitrite in cholinergic synaptosomes, unveiling a role for calcineurin B and thioredoxin

Journal of Neurochemistry

Volumn 87, Issue 6, 2003, Pages 1456-1470

  Morot Gaudry Talarmain, Y ^a   Rezaei, H ^b   Guermonprez, L ^a   Treguer, E ^b   Grosclaude, J ^b  

^a LABORATOIRE DE NEUROBIOLOGIE CELLULAIRE ET MOLÉCULAIRE   (France)

^b INRA Institut National de la Recherche Agronomique   (France)

Author keywords

Calcineurin; Cu2+; Peroxynitrite; Prion; Synaptosomes; Thioredoxin

Indexed keywords

CALCINEURIN; CHOLINE; CHOLINE ACETYLTRANSFERASE; COPPER; COPPER SULFATE; GLUTATHIONE; PEROXYNITRITE; PRION PROTEIN; RECOMBINANT PROTEIN; THIOREDOXIN;

ARTICLE; BRAIN SYNAPTOSOME; CHOLINE UPTAKE; CHOLINERGIC SYNAPSE; CONCENTRATION RESPONSE; CONTROLLED STUDY; COPPER METABOLISM; ENZYME ACTIVITY; MOTONEURON; NEUROPROTECTION; NITROSATION; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN INTERACTION; SIGNAL TRANSDUCTION; TORPEDO MARMORATA;

OVIS; TORPEDO; TORPEDO MARMORATA;

EID: 0347064330     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2003.02111.x     Document Type: Article

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