Disease-Causing SAP Mutants Are Defective in Ligand Binding and Protein Folding

Biochemistry

Volumn 42, Issue 50, 2003, Pages 14885-14892

  Li, Chengjun ^a   Iosef, Cristiana ^a   Jia, Christina Y H ^a   Gkourasas, Theofanis ^a   Han, Victor K M ^b   Li, Shawn Shun Cheng ^a,b  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

^b CHILDREN S HEALTH RESEARCH INSTITUTE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

DISEASES; GENES; MUTAGENESIS; PROTEINS;

MUTANTS; PATHOGENESIS; THERMAL DENATURATION;

BIOCHEMISTRY;

CD150 ANTIGEN; COMPLEMENTARY DNA; LIGAND; MUTANT PROTEIN; PROTEIN KINASE FYN; PROTEIN TYROSINE KINASE; SIGNALING LYMPHOCYTE ACTIVATION MOLECULE ASSOCIATED PROTEIN;

ARTICLE; DISEASE ASSOCIATION; DUNCAN DISEASE; HUMAN; LIGAND BINDING; LYMPHOPROLIFERATIVE DISEASE; MELTING POINT; MISSENSE MUTATION; PATHOGENESIS; PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN DENATURATION; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; ANTIGENS, CD; BASE SEQUENCE; CARRIER PROTEINS; CELL LINE; CHROMOSOMES, HUMAN, X; FLUORESCENCE POLARIZATION; GLYCOPROTEINS; HUMANS; IMMUNOGLOBULINS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LIGANDS; LINKAGE (GENETICS); LYMPHOPROLIFERATIVE DISORDERS; MUTAGENESIS, SITE-DIRECTED; MUTATION, MISSENSE; PROTEIN FOLDING; PROTEIN STRUCTURE, TERTIARY; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-FYN; RECEPTORS, CELL SURFACE; SIGNAL TRANSDUCTION; SRC HOMOLOGY DOMAINS;

EID: 0346995021     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi034798l     Document Type: Article

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