메뉴 건너뛰기




Volumn 7, Issue 4, 2003, Pages 387-400

Development and Validation of Computational Models for Mammalian Circadian Oscillators

Author keywords

[No Author keywords available]

Indexed keywords

ALERTNESS; ARTICLE; CALCULATION; CIRCADIAN RHYTHM; DROSOPHILA MELANOGASTER; MATHEMATICAL MODEL; OSCILLATION; PERFORMANCE; PRIORITY JOURNAL; PROTEIN STRUCTURE; VALIDATION PROCESS;

EID: 0346881222     PISSN: 15362310     EISSN: None     Source Type: Journal    
DOI: 10.1089/153623103322637698     Document Type: Article
Times cited : (14)

References (54)
  • 1
    • 0036138898 scopus 로고    scopus 로고
    • Circadian rhythms in isolated brain regions
    • ABE, M., HERZOG, E.D., YAMAZAKI, S., et al. (2002). Circadian rhythms in isolated brain regions, J. Neurosci. 22, 350-356.
    • (2002) J. Neurosci. , vol.22 , pp. 350-356
    • Abe, M.1    Herzog, E.D.2    Yamazaki, S.3
  • 2
    • 0042118234 scopus 로고    scopus 로고
    • Light-induced phase shifts in mice lacking mPER1 or mPER2
    • BAE, K., and WEAVER, D.R. (2003). Light-induced phase shifts in mice lacking mPER1 or mPER2. J. Biol. Rhythms 16, 123-133.
    • (2003) J. Biol. Rhythms , vol.16 , pp. 123-133
    • Bae, K.1    Weaver, D.R.2
  • 3
    • 0034989269 scopus 로고    scopus 로고
    • Differential functions of mPer1, mPer2, and mPer3 in the SCN circadian clock
    • BAE, K., JIN, X., MAYWOOD, E.S., et al. (2001). Differential functions of mPer1, mPer2, and mPer3 in the SCN circadian clock. Neuron 30, 525-536.
    • (2001) Neuron , vol.30 , pp. 525-536
    • Bae, K.1    Jin, X.2    Maywood, E.S.3
  • 4
    • 0032511229 scopus 로고    scopus 로고
    • Circadian rhythms in isolated brain regions
    • BALSALOBRE, A., DAMIOLA, F., and SCHIBLER, U. (1998). Circadian rhythms in isolated brain regions. Cell 93, 929-937.
    • (1998) Cell , vol.93 , pp. 929-937
    • Balsalobre, A.1    Damiola, F.2    Schibler, U.3
  • 5
    • 0034704203 scopus 로고    scopus 로고
    • Mop3 is an essential component of the master circadian pacemaker in mammals
    • BUNGER, M.K., WILSBACHER, L.D., MORAN, S.M., et al. (2000). Mop3 is an essential component of the master circadian pacemaker in mammals. Cell 103, 1009-1017.
    • (2000) Cell , vol.103 , pp. 1009-1017
    • Bunger, M.K.1    Wilsbacher, L.D.2    Moran, S.M.3
  • 6
    • 0033593306 scopus 로고    scopus 로고
    • Molecular bases for circadian clocks
    • DUNLAP, J.C. (1999). Molecular bases for circadian clocks. Cell 96, 271-290.
    • (1999) Cell , vol.96 , pp. 271-290
    • Dunlap, J.C.1
  • 7
    • 0037426839 scopus 로고    scopus 로고
    • Rhythmic histone acetylation underlies transcription in the mammalian circadian clock
    • ETCHEGARAY, J.P., LEE, C., WADE, P.A., et al. (2003). Rhythmic histone acetylation underlies transcription in the mammalian circadian clock. Nature 421, 177-182.
    • (2003) Nature , vol.421 , pp. 177-182
    • Etchegaray, J.P.1    Lee, C.2    Wade, P.A.3
  • 8
    • 0033757907 scopus 로고    scopus 로고
    • Analysis of clock proteins in mouse SCN demonstrates phylogenetic divergence of the circadian clockwork and resetting mechanisms
    • FIELD, M.D., MAYWOOD, E.S., O'BRIEN, J.A., et al. (2000). Analysis of clock proteins in mouse SCN demonstrates phylogenetic divergence of the circadian clockwork and resetting mechanisms. Neuron 25, 437-447.
    • (2000) Neuron , vol.25 , pp. 437-447
    • Field, M.D.1    Maywood, E.S.2    O'brien, J.A.3
  • 9
    • 0344736694 scopus 로고    scopus 로고
    • A detailed predictive model of the mammalian circadian clock
    • in press
    • FORGER, D.B., and PESKIN, C.S. (2003). A detailed predictive model of the mammalian circadian clock. Proc. Nat'l. Acad. Sci. USA (in press).
    • (2003) Proc. Nat'l. Acad. Sci. USA
    • Forger, D.B.1    Peskin, C.S.2
  • 10
    • 0033382102 scopus 로고    scopus 로고
    • A simpler model of the human circadian pacemaker
    • FORGER, D.B., JEWETT, M.E., and KRONAUER, R.E. (1999). A simpler model of the human circadian pacemaker. J. Biol. Rhythms 14, 532-537.
    • (1999) J. Biol. Rhythms , vol.14 , pp. 532-537
    • Forger, D.B.1    Jewett, M.E.2    Kronauer, R.E.3
  • 11
    • 0036551787 scopus 로고    scopus 로고
    • Reconciling mathematical models of biological clocks by averaging on approximate manifolds
    • FORGER, D.B., and KRONAUER, R.E. (2002). Reconciling mathematical models of biological clocks by averaging on approximate manifolds. SIAM J. Appl. Math. 62, 1281.
    • (2002) SIAM J. Appl. Math. , vol.62 , pp. 1281
    • Forger, D.B.1    Kronauer, R.E.2
  • 12
    • 0032486330 scopus 로고    scopus 로고
    • Role of the CLOCK protein in the mammalian circadian mechanism
    • GEKAKIS, N., STAKNIS, D., NGUYEN, H.B., et al. (1998). Role of the CLOCK protein in the mammalian circadian mechanism. Science 280, 1564-1569.
    • (1998) Science , vol.280 , pp. 1564-1569
    • Gekakis, N.1    Staknis, D.2    Nguyen, H.B.3
  • 13
    • 0029094843 scopus 로고
    • A model for circadian oscillations in the Drosophila period protein (PER)
    • GOLDBETER, A. (1995). A model for circadian oscillations in the Drosophila period protein (PER). Proc. R. Soc. Lond. B Biol. Sci. 261, 319-324.
    • (1995) Proc. R. Soc. Lond. B Biol. Sci. , vol.261 , pp. 319-324
    • Goldbeter, A.1
  • 14
    • 0033563379 scopus 로고    scopus 로고
    • Differential regulation of mPER1 and mTIM proteins in the mouse suprachiasmatic nuclei: New insights into a core clock mechanism
    • HASTINGS, M.H., FIELD, M.D., MAYWOOD, E.S., et al. (1999). Differential regulation of mPER1 and mTIM proteins in the mouse suprachiasmatic nuclei: new insights into a core clock mechanism. J. Neurosci. 19, RC11.
    • (1999) J. Neurosci. , vol.19
    • Hastings, M.H.1    Field, M.D.2    Maywood, E.S.3
  • 15
    • 0032242758 scopus 로고    scopus 로고
    • Clock controls circadian period in isolated suprachiasmatic nucleus neurons
    • HERZOG, E.D., TAKAHASHI, J.S., and BLOCK, G.D. (1998). Clock controls circadian period in isolated suprachiasmatic nucleus neurons. Nat. Neurosci. 1, 708-713.
    • (1998) Nat. Neurosci. , vol.1 , pp. 708-713
    • Herzog, E.D.1    Takahashi, J.S.2    Block, G.D.3
  • 16
    • 0032510778 scopus 로고    scopus 로고
    • The basic-helix-loop-helix-PAS orphan MOP3 forms transcriptionally active complexes with circadian and hypoxia factors
    • HOGENESCH, J.B., GU, Y.-Z., JAIN, S., et al. (1998). The basic-helix-loop-helix-PAS orphan MOP3 forms transcriptionally active complexes with circadian and hypoxia factors. Proc. Natl. Acad. Sci. USA 95, 5474-5479.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 5474-5479
    • Hogenesch, J.B.1    Gu, Y.-Z.2    Jain, S.3
  • 17
    • 0037167847 scopus 로고    scopus 로고
    • Dec1 and Dec2 are regulators of the mammalian molecular clock
    • HONMA, S., KAWAMOTO, T., TAKAGI, Y., et al. (2002). Dec1 and Dec2 are regulators of the mammalian molecular clock. Nature 419, 841-844.
    • (2002) Nature , vol.419 , pp. 841-844
    • Honma, S.1    Kawamoto, T.2    Takagi, Y.3
  • 18
    • 0032555044 scopus 로고    scopus 로고
    • Refinement of a limit cycle oscillator model of the effects of light on the human circadian pacemaker
    • JEWETT, M.E., and KRONAUER, R.E. (1998). Refinement of a limit cycle oscillator model of the effects of light on the human circadian pacemaker. J. Theor. Biol. 192, 455-465.
    • (1998) J. Theor. Biol. , vol.192 , pp. 455-465
    • Jewett, M.E.1    Kronauer, R.E.2
  • 19
    • 0033368295 scopus 로고    scopus 로고
    • Interactive mathematical models of subjective alertness and cognitive throughput in humans
    • JEWETT, M.E., and KRONAUER, R.E. (1999). Interactive mathematical models of subjective alertness and cognitive throughput in humans. J. Biol. Rhythms 14, 588-597.
    • (1999) J. Biol. Rhythms , vol.14 , pp. 588-597
    • Jewett, M.E.1    Kronauer, R.E.2
  • 20
    • 0033388797 scopus 로고    scopus 로고
    • Revised limit cycle oscillator model of human circadian pacemaker
    • JEWETT, M.E., FORGER, D.B., and KRONAUER, R.E. (1999). Revised limit cycle oscillator model of human circadian pacemaker. J. Biol. Rhythms 14, 493-499.
    • (1999) J. Biol. Rhythms , vol.14 , pp. 493-499
    • Jewett, M.E.1    Forger, D.B.2    Kronauer, R.E.3
  • 21
    • 0033534628 scopus 로고    scopus 로고
    • A molecular mechanism regulating rhythmic output from the suprachiasmatic circadian clock
    • JIN, X., SHEARMAN, L.P., WEAVER, D.R., et al. (1999). A molecular mechanism regulating rhythmic output from the suprachiasmatic circadian clock. Cell 96, 57-68.
    • (1999) Cell , vol.96 , pp. 57-68
    • Jin, X.1    Shearman, L.P.2    Weaver, D.R.3
  • 22
    • 20244377493 scopus 로고    scopus 로고
    • Positional cloning of the mouse circadian Clock gene
    • KING, D.P., ZHAO, Y., SANGORAM, A.M., et al. (1997). Positional cloning of the mouse circadian Clock gene. Cell 89, 641-653.
    • (1997) Cell , vol.89 , pp. 641-653
    • King, D.P.1    Zhao, Y.2    Sangoram, A.M.3
  • 23
    • 0033597904 scopus 로고    scopus 로고
    • mCRY1 and mCRY2 are essential components of the negative limb of the circadian clock feedback loop
    • KUME, K., ZYLKA, M. J., SRIRAM, S., et al. (1999). mCRY1 and mCRY2 are essential components of the negative limb of the circadian clock feedback loop. Cell 98, 193-205.
    • (1999) Cell , vol.98 , pp. 193-205
    • Kume, K.1    Zylka, M.J.2    Sriram, S.3
  • 24
    • 0033381569 scopus 로고    scopus 로고
    • Quantifying human circadian pacemaker response to brief, extended, and repeated light stimuli over the phototopic range
    • KRONAUER, R.E., FORGER, D.B., and JEWETT, M.E. (1999). Quantifying human circadian pacemaker response to brief, extended, and repeated light stimuli over the phototopic range. J. Biol. Rhythms 14, 500-515.
    • (1999) J. Biol. Rhythms , vol.14 , pp. 500-515
    • Kronauer, R.E.1    Forger, D.B.2    Jewett, M.E.3
  • 25
    • 0035966317 scopus 로고    scopus 로고
    • Posttranslational mechanisms regulate the mammalian circadian clock
    • LEE, C., ETCHEGARAY, J.P., CAGAMPANG, F.R., et al. (2001). Posttranslational mechanisms regulate the mammalian circadian clock. Cell 107, 855-867.
    • (2001) Cell , vol.107 , pp. 855-867
    • Lee, C.1    Etchegaray, J.P.2    Cagampang, F.R.3
  • 26
    • 0031990984 scopus 로고    scopus 로고
    • A model for circadian rhythms in Drosophila incorporating the formation of a complex between the PER and TIM proteins
    • LELOUP, J.-C., and GOLDBETER, A. (1998). A model for circadian rhythms in Drosophila incorporating the formation of a complex between the PER and TIM proteins. J. Biol. Rhythms 13, 70-87.
    • (1998) J. Biol. Rhythms , vol.13 , pp. 70-87
    • Leloup, J.-C.1    Goldbeter, A.2
  • 27
    • 0033532569 scopus 로고    scopus 로고
    • Chaos and birhythmicity in a model for circadian oscillations of the PER and TIM proteins in Drosophila
    • LELOUP, J.-C., and GOLDBETER, A. (1999). Chaos and birhythmicity in a model for circadian oscillations of the PER and TIM proteins in Drosophila. J. Theor. Biol. 198, 445-459.
    • (1999) J. Theor. Biol. , vol.198 , pp. 445-459
    • Leloup, J.-C.1    Goldbeter, A.2
  • 28
    • 0037795575 scopus 로고    scopus 로고
    • Toward a detailed computational model for the mammalian circadian clock
    • LELOUP, J.-C., and GOLDBETER, A. (2003). Toward a detailed computational model for the mammalian circadian clock. Proc. Natl. Acad. Sci. USA 100, 7051-7056.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 7051-7056
    • Leloup, J.-C.1    Goldbeter, A.2
  • 29
    • 0031469709 scopus 로고    scopus 로고
    • Cellular construction of a circadian clock: Period determination in the suprachiasmatic nuclei
    • LIU, C., WEAVER, D.R., STROGATZ, S.H., et al. (1997). Cellular construction of a circadian clock: period determination in the suprachiasmatic nuclei. Cell 91, 855-860.
    • (1997) Cell , vol.91 , pp. 855-860
    • Liu, C.1    Weaver, D.R.2    Strogatz, S.H.3
  • 30
    • 0035834153 scopus 로고    scopus 로고
    • Angiotensin II induces circadian gene expression of clock genes in cultured vascular smooth muscle cells
    • NONAKA, H., EMOTO, N., IKEDA, K., et al. (2001). Angiotensin II induces circadian gene expression of clock genes in cultured vascular smooth muscle cells. Circulation 104, 1746-1748.
    • (2001) Circulation , vol.104 , pp. 1746-1748
    • Nonaka, H.1    Emoto, N.2    Ikeda, K.3
  • 31
    • 0037178787 scopus 로고    scopus 로고
    • The orphan nuclear receptor REV-ERB-alpha controls circadian transcription within the positive limb of the mammalian circadian oscillator
    • PREITNER, N., DAMIOLA, F., LOPEZ-MOLINA, L., et al. (2002). The orphan nuclear receptor REV-ERB-alpha controls circadian transcription within the positive limb of the mammalian circadian oscillator. Cell 110, 251-260.
    • (2002) Cell , vol.110 , pp. 251-260
    • Preitner, N.1    Damiola, F.2    Lopez-Molina, L.3
  • 32
    • 0033820447 scopus 로고    scopus 로고
    • Comparing clockworks: Mouse versus fly
    • REPPERT, S.M., and WEAVER, D.R. (2000). Comparing clockworks: mouse versus fly. J. Biol. Rhythms 15, 357-364.
    • (2000) J. Biol. Rhythms , vol.15 , pp. 357-364
    • Reppert, S.M.1    Weaver, D.R.2
  • 33
    • 0037194790 scopus 로고    scopus 로고
    • Molecular bases for circadian clocks
    • REPPERT, S.M., and WEAVER, D.R. (2002). Molecular bases for circadian clocks. Nature 418, 935-941.
    • (2002) Nature , vol.418 , pp. 935-941
    • Reppert, S.M.1    Weaver, D.R.2
  • 34
    • 0141509017 scopus 로고    scopus 로고
    • Peripheral circadian rhythms in mammals: Time and food
    • SCHIBLER, U., RIPPERGER J., and BROWN, S.A. (2003). Peripheral circadian rhythms in mammals: time and food. J. Biol. Rhythms 18, 250-260.
    • (2003) J. Biol. Rhythms , vol.18 , pp. 250-260
    • Schibler, U.1    Ripperger, J.2    Brown, S.A.3
  • 35
    • 0033847103 scopus 로고    scopus 로고
    • Targeted disruption of the mPer3 gene: Subtle effects on circadian clock function
    • SHEARMAN, L.P., JIN, X., LEE, C., et al. (2000a). Targeted disruption of the mPer3 gene: subtle effects on circadian clock function. Mol. Cell. Biol. 20, 6269-6275.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 6269-6275
    • Shearman, L.P.1    Jin, X.2    Lee, C.3
  • 36
    • 0034640253 scopus 로고    scopus 로고
    • Interacting molecular loops in the mammalian circadian clock
    • SHEARMAN, L.P., SRIRAM, S., WEAVER, D.R., et al. (2000b). Interacting molecular loops in the mammalian circadian clock. Science 288, 1013-1019.
    • (2000) Science , vol.288 , pp. 1013-1019
    • Shearman, L.P.1    Sriram, S.2    Weaver, D.R.3
  • 37
    • 0036840199 scopus 로고    scopus 로고
    • A reduced model clarifies the role of feedback loops and time delays in the Drosophila circadian oscillator
    • SMOLEN, P., BAXTER, D.A., and BYRNE, J.H. (2002). A reduced model clarifies the role of feedback loops and time delays in the Drosophila circadian oscillator. Biophys. J. 83, 2349-2359.
    • (2002) Biophys. J. , vol.83 , pp. 2349-2359
    • Smolen, P.1    Baxter, D.A.2    Byrne, J.H.3
  • 38
    • 0035449932 scopus 로고    scopus 로고
    • Modeling circadian oscillations with interlocking positive and negative feedback loops
    • SMOLEN, P., BAXTER, D.A., and BYRNE, J.H. (2001). Modeling circadian oscillations with interlocking positive and negative feedback loops. J. Neurosci. 21, 6644-6656.
    • (2001) J. Neurosci. , vol.21 , pp. 6644-6656
    • Smolen, P.1    Baxter, D.A.2    Byrne, J.H.3
  • 39
    • 0034667673 scopus 로고    scopus 로고
    • Light- and glutamate-induced degradation of the circadian oscillating protein BMAL1 during the mammalian clock resetting
    • TAMARU, T., ISOJIMA, Y., YAMADA, T., et al. (2000). Light- and glutamate-induced degradation of the circadian oscillating protein BMAL1 during the mammalian clock resetting. J. Neurosci. 20, 7525-7530.
    • (2000) J. Neurosci. , vol.20 , pp. 7525-7530
    • Tamaru, T.1    Isojima, Y.2    Yamada, T.3
  • 40
    • 0032758081 scopus 로고    scopus 로고
    • A simple model of circadian rhythms based on dimerization and proteolysis of PER and TIM
    • TYSON, J.J., HONG, C.I., THRON C.D., et al. (1999). A simple model of circadian rhythms based on dimerization and proteolysis of PER and TIM. Biophys. J. 77, 2411-2417.
    • (1999) Biophys. J. , vol.77 , pp. 2411-2417
    • Tyson, J.J.1    Hong, C.I.2    Thron, C.D.3
  • 41
    • 0036682099 scopus 로고    scopus 로고
    • A transcription factor response element for gene expression during circadian night
    • UEDA, H. R., CHEN, W., ADACHI, A., et al. (2002). A transcription factor response element for gene expression during circadian night. Nature 418, 534-539.
    • (2002) Nature , vol.418 , pp. 534-539
    • Ueda, H.R.1    Chen, W.2    Adachi, A.3
  • 42
    • 0035927611 scopus 로고    scopus 로고
    • Robust oscillations within the interlocked feedback model of Drosophila circadian rhythm
    • UEDA, H.R., HAGIWARA, M., and KITANO, H. (2001). Robust oscillations within the interlocked feedback model of Drosophila circadian rhythm. J. Theor. Biol. 210, 401-406.
    • (2001) J. Theor. Biol. , vol.210 , pp. 401-406
    • Ueda, H.R.1    Hagiwara, M.2    Kitano, H.3
  • 43
    • 0033560863 scopus 로고    scopus 로고
    • Mammalian Cry1 and Cry2 are essential for maintenance of circadian rhythms
    • VAN DER HORST, G.T., MUIJTJENS, M., KOBAYASHI, K., et al. (1999). Mammalian Cry1 and Cry2 are essential for maintenance of circadian rhythms. Nature 398, 627-630.
    • (1999) Nature , vol.398 , pp. 627-630
    • Van Der Horst, G.T.1    Muijtjens, M.2    Kobayashi, K.3
  • 44
    • 0028241271 scopus 로고
    • Mutagenesis and mapping of a mouse gene, Clock, essential for circadian behavior
    • VITATERNA, M.H., KING, D.P., CHANG, A.M., et al. (1994). Mutagenesis and mapping of a mouse gene, Clock, essential for circadian behavior. Science 264, 719-725.
    • (1994) Science , vol.264 , pp. 719-725
    • Vitaterna, M.H.1    King, D.P.2    Chang, A.M.3
  • 45
    • 2242456966 scopus 로고    scopus 로고
    • Differential regulation of mammalian period genes and circadian rhythmicity by cryptochromes 1 and 2
    • VITATERNA, M.H., SELBY, C.P., TODO, T., et al. (1999). Differential regulation of mammalian period genes and circadian rhythmicity by cryptochromes 1 and 2. Proc. Natl. Acad. Sci. USA 96, 12114-12119.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 12114-12119
    • Vitaterna, M.H.1    Selby, C.P.2    Todo, T.3
  • 46
    • 0041666349 scopus 로고    scopus 로고
    • Light does not degrade the constitutively expressed BMAL1 protein in the mouse suprachiasmatic nucleus
    • VON GALL, C., NOTON, E., LEE, C., et al. (2003). Light does not degrade the constitutively expressed BMAL1 protein in the mouse suprachiasmatic nucleus. Eur. J. Neurosci. 18, 125-133.
    • (2003) Eur. J. Neurosci. , vol.18 , pp. 125-133
    • Von Gall, C.1    Noton, E.2    Lee, C.3
  • 47
    • 0028904194 scopus 로고
    • Individual neurons dissociated from rat suprachiasmatic nucleus express independently phased circadian firing rhythms
    • WELSH, D.K., LOGOTHETIS, D.E., MEISTER, M., et al. (1995). Individual neurons dissociated from rat suprachiasmatic nucleus express independently phased circadian firing rhythms. Neuron 14, 697-706.
    • (1995) Neuron , vol.14 , pp. 697-706
    • Welsh, D.K.1    Logothetis, D.E.2    Meister, M.3
  • 48
    • 0035853525 scopus 로고    scopus 로고
    • Molecular mechanisms of the biological clock in cultured fibroblasts
    • YAGITA, K., TAMANINI, F., VAN DER HORST, G.T., et al. (2001). Molecular mechanisms of the biological clock in cultured fibroblasts. Science 292, 278.
    • (2001) Science , vol.292 , pp. 278
    • Yagita, K.1    Tamanini, F.2    Van Der Horst, G.T.3
  • 49
    • 0034724728 scopus 로고    scopus 로고
    • Resetting central and peripheral circadian oscillators in transgenic rats
    • YAMAZAKI, S., NUMANO, R., ABE, M., et al. (2000). Resetting central and peripheral circadian oscillators in transgenic rats. Science 288, 682-685.
    • (2000) Science , vol.288 , pp. 682-685
    • Yamazaki, S.1    Numano, R.2    Abe, M.3
  • 50
    • 0035458732 scopus 로고    scopus 로고
    • Time zones: A comparative genetics of circadian clocks
    • YOUNG, M.W., and KAY, S.A. (2001). Time zones: a comparative genetics of circadian clocks. Nat. Rev. Genet. 2, 702-715.
    • (2001) Nat. Rev. Genet. , vol.2 , pp. 702-715
    • Young, M.W.1    Kay, S.A.2
  • 52
    • 0035368681 scopus 로고    scopus 로고
    • Nonredundant roles of the mPer1 and mPer2 genes in the mammalian circadian clock
    • ZHENG, B., ALBRECHT, U., KAASIK, K., et al. (2001). Nonredundant roles of the mPer1 and mPer2 genes in the mammalian circadian clock. Cell 105, 683-694.
    • (2001) Cell , vol.105 , pp. 683-694
    • Zheng, B.1    Albrecht, U.2    Kaasik, K.3
  • 53
    • 0033536228 scopus 로고    scopus 로고
    • The mPer2 gene encodes a functional component of the mammalian circadian clock
    • ZHENG, B., LARKIN, D.W., ALBRECHT, U., et al. (1999). The mPer2 gene encodes a functional component of the mammalian circadian clock. Nature 400, 169-173.
    • (1999) Nature , vol.400 , pp. 169-173
    • Zheng, B.1    Larkin, D.W.2    Albrecht, U.3
  • 54
    • 0032102386 scopus 로고    scopus 로고
    • Three Period homologs in mammals: Differential light responses in the suprachiasmatic circadian clock and oscillating transcripts outside of brain
    • ZYLKA, M.J., SHEARMAN, L.P., WEAVER, D.R., et al. (1998). Three Period homologs in mammals: differential light responses in the suprachiasmatic circadian clock and oscillating transcripts outside of brain. Neuron 20, 1103-1110.
    • (1998) Neuron , vol.20 , pp. 1103-1110
    • Zylka, M.J.1    Shearman, L.P.2    Weaver, D.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.