Effect of Angiotensin II Type 2 Receptor Blockade on Activation of Mitogen-Activated Protein Kinases after Ischemia-Reperfusion in Isolated Working Rat Hearts

Journal of Cardiovascular Pharmacology and Therapeutics

Volumn 8, Issue 4, 2003, Pages 285-296

  Kumar, Dinender ^a   Menon, Vijayan ^c   Ford, William R ^b   Clanachan, Alexander S ^c   Jugdutt, Bodh I ^c,d  

^a University of Wisconsin Cardiovascular Research Center   (United States)

^b CARDIFF UNIVERSITY   (United Kingdom)

^c UNIVERSITY OF ALBERTA   (Canada)

^d UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Angiotensin; Ischemia; Protein kinases; Receptors; Reperfusion

Indexed keywords

1 (4 DIMETHYLAMINO 3 METHYLBENZYL) 5 DIPHENYLACETYL 4,5,6,7 TETRAHYDRO 1H IMIDAZO[4,5 C]PYRIDINE 6 CARBOXYLIC ACID; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; ANGIOTENSIN 2 RECEPTOR ANTAGONIST; ANGIOTENSIN RECEPTOR ANTAGONIST; CYCLIC GMP; LOSARTAN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; NITRIC OXIDE; PROTEIN KINASE C; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME IMMUNOASSAY; HEART LEFT VENTRICLE FAILURE; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; HEART PROTECTION; ISOLATED HEART; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

EID: 0346729892     PISSN: 10742484     EISSN: None     Source Type: Journal    
DOI: 10.1177/107424840300800406     Document Type: Article

References (48)

1. Sugden PH, Clerk A. "Stress-responsive" mitogen-activated protein kinases (c-Jun N-terminal kinases and p38 mitogen-activated protein kinases) in the myocardium. Circ Res 83:345-352, 1998
2. Matsubara H. Pathophysiological role of angiotensin II type 2 receptor in cardiovascular and renal diseases. Circ Res 83:1182-1191, 1998
3. Horiuchi M, Akishita M, Dzau VJ. Recent progress in angiotensin type 2 receptor research in the cardiovascular system. Hypertension 33:613-621, 1999
4. Yoshiyama M, Kim S, Yamagishi H, et al. Cardioprotective effect of the angiotensin II type 1 receptor antagonist TCV-116 on ischemia-reperfusion injury. Am Heart J 128:1-6, 1994
5. Youhua Z, Shouchun X. Increased vulnerability of hypertrophied myocardium to ischemia and reperfusion injury. Relation to cardiac renin-angiotensin system. Chin Med J 108:28-32, 1995
6. 2 receptor antagonists on recovery of mechanical function after ischemia-reperfusion in isolated working rat hearts. Circulation 94:3087-3089, 1996
7. 2receptor expression and blockade after acute ischemia-reperfusion in isolated working rat hearts. Am J Physiol 282:H1206-H1215, 2002
8. Xu Y, Clanachan AS, Jugdutt BI. Enhanced expression of angiotensin II type 2 receptor, inositol 1,4, 5-trisphosphate receptor, and protein kinase Cε during cardioprotection induced by angiotensin II type 2 receptor blockade. Hypertension 36:506-510, 2000
9. 2 receptor stimulation increases aortic cyclic GMP in SHRSP by a kinin-dependent mechanism. Hypertension 31:349-355, 1998
10. 2 receptor activation, bradykinin and prostaglandins in pigs. J Am Coll Cardiol 32:1787-1796, 1998
11. 2 receptor expression, and IP3 receptor and PKCε proteins. J Renin Angiotensin Aldosterone Syst 1:184-195, 2000
12. 1 receptor blockade after reperfused myocardial infarction. J Renin-Angiotensin Aldosterone Syst 2:134-140, 2001
13. Cobb MH, Goldsmith EJ. How MAP kinases are regulated. J Biol Chem 270:14843-14846, 1995
14. Ushio-Fukai M, Alexander RW, Akers M, et al. p38 Mitogen-activated protein kinase is a critical component of the redox-sensitive signaling pathways activated by angiotensin II. Role in vascular smooth muscle cell hypertrophy. J Biol Chem 273:15022-15029, 1998
15. Hayashida W, Kihara Y, Yasaka A, et al. Stage-specific differential activation of mitogen-activated protein kinases in hypertrophied and failing rat hearts. J Mol Cell Cardiol 33:733-744, 2001
16. Schmitz U, Ishida T, Ishida M, et al. Angiotensin II stimulates p21-activated kinase in vascular smooth muscle cells: Role in activation of JNK. Circ Res 82:1272-1278, 1998
17. Kudoh S, Komuro I, Mizuno T, et al. Angiotensin II stimulates c-Jun NH2-terminal kinase in cultured cardiac myocytes of neonatal rats. Circ Res 80:139-146, 1997
18. Xia Z, Dickens M, Raingeaud J, et al. Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science 270:1326-1331, 1995
19. 2+-dependent signaling. Circ Res 76:1-15, 1995
20. Hayashida W, Horiuchi M, Dzau VJ. Intracellular third loop domain of angiotensin II type-2 receptor. Role in mediating signal transduction and cellular function. J Biol Chem 271:21985-21992, 1996
21. Ping P, Takano H, Zhang J, et al. Isoform-selective activation of protein kinase C by nitric oxide in the heart of conscious rabbits: A signaling mechanism for both nitric oxide-induced and ischemia-induced preconditioning. Circ Res 84:587-604, 1999
22. Zhao TC, Hines DS, Kukreja RC. Adenosine-induced late preconditioning in mouse hearts: Role of p38 MAP kinase and mitochondrial K(ATP) channels. Am J Physiol 280:H1278-H1285, 2001
23. Yang BC, Phillips MI, Ambeuhl PEJ, et al. Increase in angiotensin II type 1 receptor expression immediately after ischemia-reperfusion in isolated rat hearts. Circulation 96:922-926, 1997
24. 2) receptor protein in rat heart. Hypertension 32:78-83, 1998
25. 2 receptors: Evidence for selective sorting of receptor and ligand. Mol Endocrinol 11:1266-1277, 1997
26. 1 receptor mRNA. Circ Res 83:552-559, 1998
27. Chen H, Zhang YC, Li D, et al. Protection against myocardial dysfunction induced by global ischemia-reperfusion by antisense-oligodeoxynucleotides directed at β1-adrenoreceptor mRNA. J Pharmacol Exp Ther 294:722-727, 2000
28. Di Napoli P, Taccardi AA, Grilli A, et al. Simvastatin reduces reperfusion injury by modulating nitric oxide synthase expression: An ex vivo study in isolated working rat hearts. Cardiovasc Res 51:283-293, 2001
29. 1 receptor-mediated pressor and chronotropic effects. J Clin Invest 101:527-535, 1998
30. Ford WR, Clanachan AS, Lopaschuk GD, et al. Intrinsic AngII type 1 receptor stimulation contributes to recovery of postischemic mechanical function. Am J Physiol 274:H1524-H1531, 1998
31. Liu Y, Tsuchida A, Cohen MV, et al. Pretreatment with angiotensin II activates protein kinase C and limits myocardial infarction in isolated rabbit hearts. J Mol Cell Cardiol 27:883-892, 1995
32. Liu YH, Yang XP, Sharov VG, et al. Effects of angiotensin-converting enzyme inhibitors and angiotensin II type 1 receptor antagonists in rats with heart failure: Role of kinins and angiotensin type 2 receptors. J Clin Invest 99:1926-1935, 1997
33. 1 receptor blockade after reperfused myocardial infarction. J Renin Angiotensin Aldosterone Syst 2:134-140, 2001
34. 1 receptor blockade in reperfused myocardial infarction. In Dhalla N (ed): Signal Transduction and Cardiac Hypertrophy. Kluwer Academic Publishers, Boston, pp. 221-236, 2002
35. 2 receptor mediates inhibition of cell proliferation in coronary endothelial cells. J Clin Invest 95:651-657, 1995
36. Yamada T, Horiuchi M, Dzau VJ. Angiotensin II type 2 receptor mediates programmed cell death. Proc Natl Acad Sci USA 93:156-160, 1996
37. Yue TL, Wang C, Gu JL, et al. Inhibition of extracellular signal-regulated kinase enhances ischemia/reoxygenation-induced apoptosis in cultured cardiac myocytes and exaggerates reperfusion injury in isolated perfused heart. Circ Res 86:692-699, 2000
38. Weinbrenner C, Liu GS, Cohen MV, et al. Phosphorylation of tyrosine 182 of p38 mitogen-activated protein kinase correlates with the protection of preconditioning in the rabbit heart. J Mol Cell Cardiol 29:2383-2391, 1997
39. Sanada S, Kitakaze M, Papst PJ, et al. Role of phasic dynamism of p38 mitogen-activated protein kinase activation in ischemic preconditioning of the canine heart. Circ Res 88:175-180, 2001
40. Nakano A, Baines CP, Kim SO, et al. Ischemic preconditioning activates MAPK APK2 in the isolated rabbit heart: Evidence for involvement of p38 MAPK. Circ Res 86:144-151, 2000
41. Bogoyevitch MA, Gillespie-Brown J, Ketterman AJ, et al. Stimulation of the stress-activated mitogen-activated protein kinase subfamilies in perfused heart. p38/RK mitogen-activated protein kinases and c-Jun N-terminal kinases are activated by ischemia/reperfusion. Circ Res 79:162-173, 1996
42. Wang Y, Huang S, Sah VP, et al. Cardiac muscle cell hypertrophy and apoptosis induced by distinct members of the p38 mitogen-activated protein kinase family. J Biol Chem 273:2161-2168, 1998
43. Clerk A, Michael A, Sugden PH. Stimulation of the p38 mitogen-activated protein neonatal rat ventricular myocytes by the G protein-coupled receptor agonists, endothelin-1 and phenylephrine: A role in cardiac myocyte hypertrophy? J Cell Biol 142:523-535, 1998
44. Bartunek J, Weinberg EO, Tajima M, et al. Angiotensin II type 2 receptor blockade amplifies the early signals of cardiac growth response to angiotensin II in hypertrophied hearts. Circulation 99:22-25, 1999
45. Wang X, Martindale JL, Liu Y, et al. The cellular response to oxidative stress: Influences of mitogen-activated protein kinase signaling pathways on cell survival. Biochem J 333:291-300, 1998
46. Wang LX, Ideishi M, Yahiro E, et al. Mechanism of the cardioprotective effect of inhibition of the renin-angiotensin system on ischemia/reperfusion-induced myocardial injury. Hypertens Res 24:179-187, 2001
47. Sugden PH, Clerk A. Cellular mechanisms of cardiac hypertrophy. J Mol Med 76:725-746, 1998
48. Moudgil R, Menon V, Xu Y, et al. Postischemic apoptosis and functional recovery after angiotensin II type 1 receptor blockade in working rat hearts. J Hypertens 19:1121-1129, 2001