Stage-specific differential activation of mitogen-activated protein kinases in hypertrophied and failing rat hearts

Journal of Molecular and Cellular Cardiology

Volumn 33, Issue 4, 2001, Pages 733-744

  Hayashida, Wataru ^a   Kihara, Yasuki ^a   Yasaka, Asuka ^a   Inagaki, Koichi ^a   Iwanaga, Yoshitaka ^a   Sasayama, Shigetake ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

Angiotensin; Heart failure; Hypertrophy; Signal transduction

Indexed keywords

ANGIOTENSIN; MITOGEN ACTIVATED PROTEIN KINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; CELL DEATH; CONFERENCE PAPER; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME SPECIFICITY; HEART FAILURE; HEART HYPERTROPHY; ISOLATED HEART; NEGATIVE FEEDBACK; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RAT; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

EID: 0034970745     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmcc.2001.1341     Document Type: Conference Paper

References (42)

1. 2+-dependent signaling
2. 2-terminal kinase in cultured cardiac myocytes of neonatal rats
3. Stimulation of the p38 mitogen-activated protein kinase pathway in neonatal rat ventricular myocytes by the G protein-coupled receptor agonists, endothelin-1 and phenylephrine: A role in cardiac myocyte hypertrophy?
4. The MEKK-JNK pathway is stimulated by α1-adrenergic receptor and Ras activation and is associated with in vitro and in vivo cardiac hypertrophy
5. A role for the p38 mitogen-activated protein kinase pathway in myocardial cell growth, sarcomeric organization, and cardiac-specific gene expression
6. Cardiac muscle cell hypertrophy and apoptosis induced by distinct members of the p38 mitogen-activated protein kinase family
7. Transition from compensatory hypertrophy to dilated, failing ventricles in Dahl salt-sensitive rats
8. Myocardial contractile efficiency and oxygen cost of contractility are preserved during transition from compensated hypertrophy to failure in rats with salt-sensitive hypertension
9. Neurohormonal factors during transition from left ventricular hypertrophy to failure in Dahl salt-sensitive rats
10. Modulation of in vivo cardiac hypertrophy with insulin-like growth factor-1 and angiotensin-converting enzyme inhibitor: Relationship between change in myosin isoform and progression of left ventricular dysfunction
11. Intracellular third loop domain of angiotensin II type-2 receptor. Role in mediating signal transduction and cellular function
12. + exchange and ERK1/2
13. Angiotensin II-induced growth responses in isolated adult rat hearts. Evidence for load-independent induction of cardiac protein synthesis by angiotensin II
14. Left ventricular stretch stimulates angiotensin II-mediated phosphatidylinositol hydrolysis and protein kinase C ε isoform translocation in adult guinea pig hearts
15. Cardiac calcineurin during transition from hypertrophy to heart failure in rats
16. Angiotensin-converting enzyme and genetic hypertension: Cloning of rat cDNA and characterization of the enzyme
17. Isolation and characterization of rat and human glyceraldehyde-3-phosphate dehydrogenase cDNAs: Genomic complexity and molecular evolution of the gene
18. Isolation of a cDNA encoding the vascular type-1 angiotensin II receptor
19. Expression cloning of type-2 angiotensin II receptor reveals a unique class of seven-transmembrane receptors
20. Diastolic properties in canine hypertensive left ventricular hypertrophy: Effects of angiotensin converting enzyme inhibition and angiotensin II type-1 receptor blockade
21. The stress-activated protein kinase subfamily of c-Jun kinases
22. A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells
23. Differential modulation of mitogen-activated protein kinases and mitogen-activated protein kinase phosphatases in failing human myocardium
24. Decreased p38 MAPK activity is observed in failing human heart tissue
25. Structural remodeling of cardiac myocytes in patients with ischemic cardiomyopathy
26. Pathological hypertrophy and cardiac interstitium: Fibrosis and renin-angiotensinaldosterone system
27. Stimulation of the stress-activated mitogen-activated protein kinase subfamilies in perfused heart. p38/RK mitogen-activated protein kinases and c-Jun N-terminal kinases are activated by ischemia/reperfusion
28. Oxidative stress-induced actin reorganization mediated by the p38 mitogen-activated protein kinase/heat shock protein 27 pathway in vascular endothelial cells
29. Phosphorylation of tyrosine 182 of p38 mitogen-activated protein kinase correlates with the protection of preconditioning in the rabbit heart
30. Regional remodeling and nonuniform changes in diastolic function in patients with left ventricular dysfunction: Modification by long-term enalapril treatment
31. Angiotensin converting enzyme inhibition prolongs survival and modifies the transition to heart failure in rats with pressure overload hypertrophy due to ascending aortic stenosis
32. AT1 and AT2 angiotensin receptor gene expression in human heart failure
33. Selective downregulation of the angiotensin II AT1-receptor subtype in failing human ventricular myocardium
34. Altered activation of c-Jun N-terminal kinase in the hypertrophied and failing rat left ventricular myocardium
35. Selective increase in endothelin-1 and endothelin A receptor subtype in the hypertrophied myocardium of the aorto-venacaval fistula rat
36. Regulation and function of the JNK subgroup of MAP kinases
37. Role of mitogen-activated protein kinase phosphatase during the cellular response to genotoxic stress. Inhibition of c-Jun N-terminal kinase activity and AP1 dependent gene activation
38. Mitogen-activated protein kinases mediate changes in gene expression, but not cytoskeletal organization associated with cardiac muscle hypertrophy
39. Dissociation of p44 and p42 mitogen-activated protein kinase activation from receptor-induced hypertrophy in neonatal rat ventricular myocytes
40. Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis
41. Ras-dependent activation of MAP kinase pathway mediated by G-protein βγ subunits
42. Inhibition of extracellular signal-regulated kinase enhances ischemia/reoxygenation-induced apoptosis in cultured cardiac myocytes and exaggerates reperfusion injury in isolated perfused heart