Intravital microscopy identifies selectins that regulate T cell traffic into allografts

Journal of Clinical Investigation

Volumn 112, Issue 11, 2003, Pages 1714-1723

  Jones, Thomas R ^a   Shirasugi, Nozomu ^a   Adams, Andrew B ^a   Pearson, Thomas C ^a   Larsen, Christian P ^a  

^a EMORY UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

L SELECTIN; L SELECTIN LIGAND; LIGAND; SELECTIN; UNCLASSIFIED DRUG;

ADOLESCENT; ALLOGRAFT; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL MOTILITY; CELL TRANSPORT; FLUORESCENCE MICROSCOPY; GRAFT REJECTION; IMMUNE RECONSTITUTION; IMMUNITY; INFLAMMATION; INJURY; INTRAVITAL FLUORESCENCE VIDEOMICROSCOPY; INTRAVITAL MICROSCOPY; LYMPHOCYTE HOMING; MALE; MICROSCOPY; MICROVASCULATURE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REGENERATION; SCID MOUSE; SKIN ALLOGRAFT; SKIN BLOOD VESSEL; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; T LYMPHOCYTE ROLLING; VENULE;

EID: 0346690366     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI19391     Document Type: Article

References (36)

1. Banchereau, J., and Steinman, R.M. 1998. Dendritic cells and the control of immunity. Nature. 392:245-252.
2. Butcher, E.C., and Picker, L.J. 1996. Lymphocyte homing and homeostasis. Science. 272:60-66.
3. Vajkoczy, P., Laschinger, M., and Engelhardt, B. 2001. α4-Integrin-VCAM-1 binding mediates G protein-independent capture of encephalitogenic T cell blasts to CNS white matter microvessels. J. Clin. Invest. 108:557-565. doi:10.1172/JCI200112440.
4. Warnock, R.A., Askari, S., Butcher, E.C., and von Andrian, U.H. 1998. Molecular mechanisms of lymphocyte homing to peripheral lymph nodes. J. Exp. Med. 187:205-216.
5. Robert, C., and Kupper, T.S. 1999. Inflammatory skin diseases, T cells, and immune surveillance. N. Engl. J. Med. 341:1817-1828.
6. Fuhlbrigge, R.C., Kieffer, J.D., Armerding, D., and Kupper, T.S. 1997. Cutaneous lymphocyte antigen is a specialized form of PSGL-1 expressed on skin-homing. T cells. Nature. 389:978-981.
7. Weninger, W., et al. 2000 Specialized contributions by alpha(1,3)-fucosyltransferase-IV and FucT-VII during leukocyte rolling in dermal microvessels. Immunity. 12:665-676.
8. Homeister, J.W., et al. 2001. The alpha(1,3)fucosyltransferases FucT-IV and FucT-VII exert collaborative control over selectin-dependent leukocyte recruitment and lymphocyte homing. Immunity. 15:115-126.
9. Auchincloss, H., Jr., and Sultan, H. 1996. Antigen processing and presentation in transplantation. Curr. Opin. Immunol. 8:681-687.
10. Gould, D.S., and Auchincloss, H., Jr. 1999. Direct and indirect recognition: the role of MHC antigens in graft rejection. Immunol. Today. 20:77-82.
11. Fuller, T.F., et al. 2001. Reduction of severe ischemia/reperfusion injury in rat kidney grafts by a soluble P-selectin glycoprotein ligand. Transplantation. 72:216-222.
12. Farmer, D.G., et al. 2002. Improved survival through the reduction of ischemia-reperfusion injury after rat intestinal transplantation using selective P-selectin blockade with P-selectin glycoprotein ligand-Ig. Transplant. Proc. 34:985.
13. Tang, M.L., Hale, L.P., Steeber, D.A., and Tedder, T.F. 1997. L-selectin is involved in lymphocyte migration to sites of inflammation in the skin: delayed rejection of allografts in L-selectin-deficient mice. J. Immunol. 158:5191-5199.
14. Lacha, J., et al. 2002. Intercellular cell adhesion molecule-1 and selectin ligands in acute cardiac allograft rejection: a study on gene-deficient mouse models. J. Leukoc. Biol. 71:311-318.
15. Raisky, O., et al. 2001. Acute rejection and cardiac graft vasculopathy in the absence of donor-derived ICAM-1 or P-selectin. J. Heart Lung Transplant. 20:340-349.
16. Hancock, W.W., et al. 2000. Requirement of the chemokine receptor CXCR3 for acute allograft rejection. J. Exp. Med. 192:1515-1520.
17. Hancock, W.W., et al. 2001. Donor-derived IP-10 initiates development of acute allograft rejection. J. Exp. Med. 193:975-980.
18. von Andrian, U.H., and M'Rini, C. 1998. In situ analysis of lymphocyte migration to lymph nodes. Cell Adhes. Commun. 6:85-96.
19. Kupiec-Weglinski, J.W., Austyn, J.M., and Morris, P.J. 1988. Migration patterns of dendritic cells in the mouse. Traffic from the blood, and T cell-dependent and -independent entry to lymphoid tissues. J. Exp. Med. 167:632-645.
20. Larsen, C.P., Barker, H., Morris, P.J., and Austyn, J.M. 1990. Failure of mature dendritic cells of the host to migrate from the blood into cardiac or skin allografts. Transplantation. 50:294-301.
21. Bingaman, A.W., et al. 2000. Vigorous allograft rejection in the absence of danger. J. Immunol. 164:3065-3071.
22. Weninger, W., Crowley, M.A., Manjunath, N., and von Andrian, U. H. 2001. Migratory properties of naive, effector, and memory CD8(+) T cells. J. Exp. Med. 194:953-966.
23. Anderson, C.C., et al. 2001. Testing time-, ignorance-, and danger-based models of tolerance. J. Immunol. 166:3663-3671.
24. Masopust, D., Vezys, V., Marzo, A.L., and Lefrancois, L. 2001. Preferential localization of effector memory cells in nonlymphoid tissue. Science. 291:2413-2417.
25. Valujskikh, A., Lantz, O., Celli, S., Matzinger, P., and Heeger, P.S. 2002. Cross-primed CD8(+) T cells mediate graft rejection via a distinct effector pathway. Nat. Immunol. 3:844-851.
26. Clark, R.A., et al. 1982. Fibronectin is produced by blood vessels in response to injury. J. Exp. Med. 156:646-651.
27. Kansas, G.S. 1996. Selectins and their ligands: current concepts and controversies. Blood. 88:3259-3287.
28. Walter, U.M., and Issekutz, A.C. 1997. Role of E- and P-selectin in migration of monocytes and polymorphonuclear leucocytes to cytokine and chemoartractant-induced cutaneous inflammation in the rat. Immunology. 92:290-299.
29. Ley, K., Allietta, M., Bullard, D.C., and Morgan, S. 1998. Importance of E-selectin for firm leukocyte adhesion in vivo. Circ. Res. 83:287-294.
30. Lenrer, M., Levinovitz, A., Isenmann, S., and Vestweber, D. 1994. Mono-specific and common glycoprotein ligands for E- and P-selectin on myeloid cells. J. Cell Biol. 125:471-481.
31. Kerfoot, S.M., and Kubes, P. 2002. Overlapping roles of P-selectin and alpha 4 integrin to recruit leukocytes to the central nervous system in experimental autoimmune encephalomyelitis. J. Immunol. 169:1000-1006.
32. Hickey, M.J., et al. 1999. Varying roles of E-selectin and P-selectin in different microvascular beds in response to antigen. J. Immunol. 162:1137-1143.
33. Yamada, S., et al. 1995. Rolling in P-selectin-deficient mice is reduced but not eliminated in the dorsal skin. Blood. 86:3487-3492.
34. Weninger, W., et al. 2003. Naive T cell recruitment to nonlymphoid tissues: a role for endothelium-expressed CC chemokine ligand 21 in autoimmune disease and lymphoid neogenesis. J. Immunol. 170:4638-4648.
35. Takemura, S., et al. 2001. Lymphoid neogenesis in rheumatoid synovitis. J. Immunol. 167:1072-1080.
36. Pober, J.S., Orosz, C.G., Rose, M.L., and Savage, C.O. 1996. Can graft endothelial cells initiate a host anti-graft immune response? Transplantation. 61:343-349.