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Volumn 64, Issue , 1997, Pages 283-350

Anti-tumor necrosis factor-α therapy of rheumatoid arthritis

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; TUMOR NECROSIS FACTOR ALPHA ANTIBODY;

EID: 0030996312     PISSN: 00652776     EISSN: None     Source Type: Book Series    
DOI: None     Document Type: Review
Times cited : (207)

References (258)
  • 3
    • 0023085060 scopus 로고
    • Effects of recombinant human tumor necrosis factor (rhTNF) on normal human and mouse hemopoietic progenitor cells
    • Akahane, K., Hosoi, T., Urabe, A., Kawakami, M, and Takaku, F. (1987). Effects of recombinant human tumor necrosis factor (rhTNF) on normal human and mouse hemopoietic progenitor cells. Int. J. Cell Cloning 5, 16-26.
    • (1987) Int. J. Cell Cloning , vol.5 , pp. 16-26
    • Akahane, K.1    Hosoi, T.2    Urabe, A.3    Kawakami, M.4    Takaku, F.5
  • 4
    • 0027421831 scopus 로고
    • Interleukin-6 in biology and medicine
    • Akira, S., Taga, T., and Kishimoto, T. (1993). Interleukin-6 in biology and medicine. Adv. Immunol. 54, 1-78.
    • (1993) Adv. Immunol. , vol.54 , pp. 1-78
    • Akira, S.1    Taga, T.2    Kishimoto, T.3
  • 5
    • 0025801199 scopus 로고
    • Correlation of histopathological features of pannus with patterns of damage in different joints in rheumatoid arthritis
    • Allard, S. A., Muirden, K. D., and Maim, R. N. (1991). Correlation of histopathological features of pannus with patterns of damage in different joints in rheumatoid arthritis. Ann. Bheum. Dis. 50, 278-283.
    • (1991) Ann. Bheum. Dis. , vol.50 , pp. 278-283
    • Allard, S.A.1    Muirden, K.D.2    Maim, R.N.3
  • 6
    • 0025847243 scopus 로고
    • Cytokines in chronic inflammatory arthritis. VI. Analysis of the synovial cells involved in granulocyte-macrophage colony stimulating factor production and gene expression in rheumatoid arthritis and its regulation by IL-1 and TNF-alpha
    • Alvaro-Garcia, J. M., Zvaifler, N. J., Brown, C. B., Kaushansky, L., and Firestein, G. S. (1991). Cytokines in chronic inflammatory arthritis. VI. Analysis of the synovial cells involved in granulocyte-macrophage colony stimulating factor production and gene expression in rheumatoid arthritis and its regulation by IL-1 and TNF-alpha. J. Immunol. 146, 3365-3371.
    • (1991) J. Immunol. , vol.146 , pp. 3365-3371
    • Alvaro-Garcia, J.M.1    Zvaifler, N.J.2    Brown, C.B.3    Kaushansky, L.4    Firestein, G.S.5
  • 7
    • 0027501020 scopus 로고
    • Interleukin-1 receptor antagonist
    • Arend, W. P. (1993). Interleukin-1 receptor antagonist. Adv. Immunol. 54, 167-227.
    • (1993) Adv. Immunol. , vol.54 , pp. 167-227
    • Arend, W.P.1
  • 8
    • 0028075791 scopus 로고
    • Immunosuppression in insulin-dependent diabetes mellitus: From cellular selectivity towards autoantigen specificity
    • L. Adorini, Ed.),. Karger, Basel
    • Bach, J.-F., and Chatenoud, L. (1995). Immunosuppression in insulin-dependent diabetes mellitus: From cellular selectivity towards autoantigen specificity. In "Selective Immunosuppression: Basic Concepts and Clinical Applications" (L. Adorini, Ed.), Vol. 60, pp. 32-47. Karger, Basel.
    • (1995) Selective Immunosuppression: Basic Concepts and Clinical Applications , vol.60 , pp. 32-47
    • Bach, J.-F.1    Chatenoud, L.2
  • 9
    • 0025845703 scopus 로고
    • Collagen induced arthritis in an outbred group of rhesus monkeys comprising responder and non responder animals. Relationship between course of arthritis and collagen specific immunity
    • Bakker, N. P. M., van Erck, M. G. M., Botman, C. A. D., Jonker, M., and Hart, L. A. (1991). Collagen induced arthritis in an outbred group of rhesus monkeys comprising responder and non responder animals. Relationship between course of arthritis and collagen specific immunity. Arthr. Rheum. 34, 616-624.
    • (1991) Arthr. Rheum. , vol.34 , pp. 616-624
    • Bakker, N.P.M.1    van Erck, M.G.M.2    Botman, C.A.D.3    Jonker, M.4    Hart, L.A.5
  • 11
    • 0029050563 scopus 로고
    • Fetal origins of coronary heart disease
    • Barker, D. J. (1995). Fetal origins of coronary heart disease. Br. Med. J. 311, 171-174.
    • (1995) Br. Med. J. , vol.311 , pp. 171-174
    • Barker, D.J.1
  • 13
    • 0027384648 scopus 로고
    • LPS-induced sTNFreceptor release in vivo in a murine model
    • Bemelmans, M. H. A., Gouma, D. J., and Buurman, W. A. (1993). LPS-induced sTNFreceptor release in vivo in a murine model. J. Immunol. 151, 5554-5562.
    • (1993) J. Immunol. , vol.151 , pp. 5554-5562
    • Bemelmans, M.H.A.1    Gouma, D.J.2    Buurman, W.A.3
  • 14
    • 0024202995 scopus 로고
    • Association between HLA-DR2 and production of tumour necrosis factor α and interleukin 1 by mononuclear cells activated by lipopolysaccharide
    • Bendtzen, K., Morling, N., Fomsgaard, A., Svenson, M., Jakobsen, B., Odum, N., and Svejgaard, A. (1988). Association between HLA-DR2 and production of tumour necrosis factor α and interleukin 1 by mononuclear cells activated by lipopolysaccharide. Scand. J. Immunol. 28, 599-606.
    • (1988) Scand. J. Immunol. , vol.28 , pp. 599-606
    • Bendtzen, K.1    Morling, N.2    Fomsgaard, A.3    Svenson, M.4    Jakobsen, B.5    Odum, N.6    Svejgaard, A.7
  • 15
    • 0022642908 scopus 로고
    • Induction of tolerance by monoclonal antibody therapy
    • Benjamin, R. J., and Waldmann, H. (1986). Induction of tolerance by monoclonal antibody therapy. Nature 320, 449-451.
    • (1986) Nature , vol.320 , pp. 449-451
    • Benjamin, R.J.1    Waldmann, H.2
  • 16
    • 0022648104 scopus 로고
    • Stimulation of bone resorption and inhibition of bone formation in vitro by human tumour necrosis factor
    • Bertolini, D. R., Nedwin, G. E., Bringman, T. S., Smith, D. D., and Mundy, G. R. (1986). Stimulation of bone resorption and inhibition of bone formation in vitro by human tumour necrosis factor. Nature 319, 516-518.
    • (1986) Nature , vol.319 , pp. 516-518
    • Bertolini, D.R.1    Nedwin, G.E.2    Bringman, T.S.3    Smith, D.D.4    Mundy, G.R.5
  • 17
    • 0024405827 scopus 로고
    • The biology of cachectin/TNF-A primary mediator of the host response
    • Beutler, B., and Cerami, A. (1989). The biology of cachectin/TNF-A primary mediator of the host response. Annu. Rev. Immunol. 7, 625-655.
    • (1989) Annu. Rev. Immunol. , vol.7 , pp. 625-655
    • Beutler, B.1    Cerami, A.2
  • 18
    • 0022178181 scopus 로고
    • Cachectin/tumor necrosis factor: Production, distribution, and metabolic fate in vivo
    • Beutler, B. A., Milsark, I. W., and Cerami, A. (1985). Cachectin/tumor necrosis factor: Production, distribution, and metabolic fate in vivo. J. Immunol. 135, 3972-3977.
    • (1985) J. Immunol. , vol.135 , pp. 3972-3977
    • Beutler, B.A.1    Milsark, I.W.2    Cerami, A.3
  • 22
    • 0021034058 scopus 로고
    • Hypothesis: Role of aberrant HLA-DR expression and antigen presentation in the induction of endocrine autoimmunity
    • Bottazzo, G. F., Pujol-Borrell, R., Hanafusa, T., and Feldmann, M. (1983). Hypothesis: Role of aberrant HLA-DR expression and antigen presentation in the induction of endocrine autoimmunity. Lancet 2, 1115-1119.
    • (1983) Lancet , vol.2 , pp. 1115-1119
    • Bottazzo, G.F.1    Pujol-Borrell, R.2    Hanafusa, T.3    Feldmann, M.4
  • 23
    • 0025866716 scopus 로고
    • Evidence for impaired erythropoietin response to anaemia in rheumatoid disease
    • Boyd, H. K., Lappin, R. J., and Bell, A. L. (1991). Evidence for impaired erythropoietin response to anaemia in rheumatoid disease. Br. J. Rheumatol. 30, 255-259.
    • (1991) Br. J. Rheumatol. , vol.30 , pp. 255-259
    • Boyd, H.K.1    Lappin, R.J.2    Bell, A.L.3
  • 24
    • 0026531017 scopus 로고
    • Tumour necrosis factor alpha in stool as a marker of intestinal inflammation [see comments]
    • Braegger, C. P., Nicholls, S., Murch, S. H., Stephens, S., and MacDonald, T. T. (1992). Tumour necrosis factor alpha in stool as a marker of intestinal inflammation [see comments]. Lancet 339, 89-91.
    • (1992) Lancet , vol.339 , pp. 89-91
    • Braegger, C.P.1    Nicholls, S.2    Murch, S.H.3    Stephens, S.4    MacDonald, T.T.5
  • 26
    • 0024314554 scopus 로고
    • Inhibitory effect of TNF α antibodies on synovial cell interleukin-1 production in rheumatoid arthritis
    • Brennan, F. M., Chantry, D., Jackson, A., Maini, R., and Feldmann, M. (1989). Inhibitory effect of TNF α antibodies on synovial cell interleukin-1 production in rheumatoid arthritis. Lancet 2, 244-247.
    • (1989) Lancet , vol.2 , pp. 244-247
    • Brennan, F.M.1    Chantry, D.2    Jackson, A.3    Maini, R.4    Feldmann, M.5
  • 27
    • 0025346634 scopus 로고
    • Transforming growth factor-β in rheumatoid arthritis synovial tissue: Lack of effect on spontaneous cytokine production in joint cell cultures
    • Brennan, F. M., Chantry, D., Turner, M., Foxwell, B., Maini, R. N., and Feldmann, M. (1990a). Transforming growth factor-β in rheumatoid arthritis synovial tissue: Lack of effect on spontaneous cytokine production in joint cell cultures. Clin. Exp. Immunol. 81, 278-285.
    • (1990) Clin. Exp. Immunol. , vol.81 , pp. 278-285
    • Brennan, F.M.1    Chantry, D.2    Turner, M.3    Foxwell, B.4    Maini, R.N.5    Feldmann, M.6
  • 28
    • 0025043478 scopus 로고
    • Detection of interleukin 8 biological activity in synovial fluids from patients with rheumatoid arthritis and production of interleukin 8 mRNA by isolated synovial cells
    • Brennan, F. M., Zachariae, C. O., Chantry, D., Larsen, C. G., Turner, M., Maini, R. N., Matsushima, K., and Feldmann, M. (1990b). Detection of interleukin 8 biological activity in synovial fluids from patients with rheumatoid arthritis and production of interleukin 8 mRNA by isolated synovial cells. Eur. J. Immunol. 20, 2141-2144.
    • (1990) Eur. J. Immunol. , vol.20 , pp. 2141-2144
    • Brennan, F.M.1    Zachariae, C.O.2    Chantry, D.3    Larsen, C.G.4    Turner, M.5    Maini, R.N.6    Matsushima, K.7    Feldmann, M.8
  • 29
    • 0029077690 scopus 로고
    • TNF inhibitors are produced spontaneously by rheumatoid and osteoarthritic synovial joint cell cultures: Evidence of feedback control of TNF action
    • Brennan, F. M., Gibbons, D., Cope, A., Katsikis, P., Maini, R. N., and Feldmann, M. (1995). TNF inhibitors are produced spontaneously by rheumatoid and osteoarthritic synovial joint cell cultures: Evidence of feedback control of TNF action. Scand. J. Immunol. 421, 58-165.
    • (1995) Scand. J. Immunol. , vol.421 , pp. 58-165
    • Brennan, F.M.1    Gibbons, D.2    Cope, A.3    Katsikis, P.4    Maini, R.N.5    Feldmann, M.6
  • 30
    • 9844248014 scopus 로고    scopus 로고
    • Reduction in serum matrix metalloproteinase 1 and 3 in rheumatoid arthritis patients following anti-TNFa (cA2) therapy
    • press
    • Brennan, F. M, Browne, K. A., Green, P. A., Jasper, J.-M., Maini, R. N. L., and Feldmann, M. (1997). Reduction in serum matrix metalloproteinase 1 and 3 in rheumatoid arthritis patients following anti-TNFa (cA2) therapy. Br. J. Rheum, (in press).
    • (1997) Br. J. Rheum
    • Brennan, F.M.1    Browne, K.A.2    Green, P.A.3    Jasper, J.-M.4    Maini, R.N.L.5    Feldmann, M.6
  • 31
    • 0000563532 scopus 로고
    • Synovial pathology and articular erosion in rheumatoid arthritis
    • Bresnihan, B., Mulherin, D., and FitzGerald, O. (1995). Synovial pathology and articular erosion in rheumatoid arthritis. Rheumatol. Eur. 24(Suppl.), 158-160.
    • (1995) Rheumatol. Eur. , vol.24 , pp. 158-160
    • Bresnihan, B.1    Mulherin, D.2    FitzGerald, O.3
  • 32
    • 0028298754 scopus 로고
    • The megakaryocyte platelet system and vascular disease
    • Brown, A. S., and Martin, J. F. (1994). The megakaryocyte platelet system and vascular disease. Eur. J. Clin. Invest. 24(SuppI. 1), 99-115.
    • (1994) Eur. J. Clin. Invest. , vol.24 , pp. 99-115
    • Brown, A.S.1    Martin, J.F.2
  • 33
    • 0023850364 scopus 로고
    • Detection of activated T cell products in the rheumatoid joint using cDNA probes to Interleukin-2 (IL-2) IL-2 receptor and IFN-γ
    • Buchan, G., Barrett, K., Fujita, T., Taniguchi, T., Maini, R., and Feldmann, M. (1988a). Detection of activated T cell products in the rheumatoid joint using cDNA probes to Interleukin-2 (IL-2) IL-2 receptor and IFN-γ. Clin. Exp. Immunol. 71, 295-301.
    • (1988) Clin. Exp. Immunol. , vol.71 , pp. 295-301
    • Buchan, G.1    Barrett, K.2    Fujita, T.3    Taniguchi, T.4    Maini, R.5    Feldmann, M.6
  • 34
    • 0023773031 scopus 로고
    • Interleukin-1 and tumour necrosis factor mRNA expression in rheumatoid arthritis: Prolonged production of IL-lα
    • Buchan, G., Barrett, K., Turner, M., Chantry, D., Maini, R. N., and Feldmann, M. (1988b). Interleukin-1 and tumour necrosis factor mRNA expression in rheumatoid arthritis: Prolonged production of IL-lα. Clin. Exp. Immunol. 73, 449-455.
    • (1988) Clin. Exp. Immunol. , vol.73 , pp. 449-455
    • Buchan, G.1    Barrett, K.2    Turner, M.3    Chantry, D.4    Maini, R.N.5    Feldmann, M.6
  • 35
    • 0028330068 scopus 로고
    • Rheumatoid arthritis: Another New World disease?
    • Buchanan, W. W. (1994). Rheumatoid arthritis: Another New World disease? Sem. Arthr. Rheum. 23, 289-294.
    • (1994) Sem. Arthr. Rheum. , vol.23 , pp. 289-294
    • Buchanan, W.W.1
  • 36
  • 37
    • 0029617952 scopus 로고
    • Modulation of proinflammatory cytokine release in rheumatoid synovial membrane cell cultures. Comparison of monoclonal anti-TNFa antibody with the IL-1 receptor antagonist
    • Butler, D. M., Maini, R. N., Feldmann, M., and Brennan, F. M. (1995). Modulation of proinflammatory cytokine release in rheumatoid synovial membrane cell cultures. Comparison of monoclonal anti-TNFa antibody with the IL-1 receptor antagonist. Eur. Cytokine Network 6, 225-230.
    • (1995) Eur. Cytokine Network , vol.6 , pp. 225-230
    • Butler, D.M.1    Maini, R.N.2    Feldmann, M.3    Brennan, F.M.4
  • 38
    • 0006734423 scopus 로고
    • Lysosomal cysteine endopeptidases in the degradation of cartilage and bone
    • E. Davies and J. T. Dingle, Eds.),. Academic Press, London
    • Buttle, D. J. (1994). Lysosomal cysteine endopeptidases in the degradation of cartilage and bone. In "Immunopharmacology of Joints and Connective Tissue" (E. Davies and J. T. Dingle, Eds.), pp. 119-128. Academic Press, London.
    • (1994) Immunopharmacology of Joints and Connective Tissue , pp. 119-128
    • Buttle, D.J.1
  • 39
    • 0027935309 scopus 로고
    • Leukocyte-endothelial adhesion molecules
    • Carlos, T. M., and Harlan, J. M. (1994). Leukocyte-endothelial adhesion molecules. Blood 84, 2068-2101.
    • (1994) Blood , vol.84 , pp. 2068-2101
    • Carlos, T.M.1    Harlan, J.M.2
  • 41
    • 23544454730 scopus 로고
    • Regulation of STNF Rad IL-6 following TNF blockade in RA: In vivo evidence for a cytokine cascade
    • abstract
    • Charles, P., Potter, A., Elliott, M., Cope, A., Woody, J., Feldmann, M. L., and Maini, R. N. (1995). Regulation of STNF Rad IL-6 following TNF blockade in RA: In vivo evidence for a cytokine cascade. Arth. Rheum. 38, S352. [abstract]
    • (1995) Arth. Rheum. , vol.38 , pp. S352
    • Charles, P.1    Potter, A.2    Elliott, M.3    Cope, A.4    Woody, J.5    Feldmann, M.L.6    Maini, R.N.7
  • 42
    • 0026591848 scopus 로고
    • Defective hypothalamic response to immune and inflammatory stimuli in patients with rheumatoid arthritis
    • Chikanza, I. C, Petrou, P., Kingsley, G., Chrousos, G., and Panayi, G. S. (1992). Defective hypothalamic response to immune and inflammatory stimuli in patients with rheumatoid arthritis. Arthr. Rheum. 35, 1281.
    • (1992) Arthr. Rheum. , vol.35 , pp. 1281
    • Chikanza, I.C.1    Petrou, P.2    Kingsley, G.3    Chrousos, G.4    Panayi, G.S.5
  • 44
    • 0026656620 scopus 로고
    • Treatment of rheumatoid arthritis with single dose or weekly pulses of chimaeric anti-CD4 monoclonal antibody
    • Choy, E. H., Chikanza, I. C, Kingsley, G., Corrigall, V., and Panayi, G. S. (1992). Treatment of rheumatoid arthritis with single dose or weekly pulses of chimaeric anti-CD4 monoclonal antibody. Scand. J. Immunol. 36, 291-298.
    • (1992) Scand. J. Immunol. , vol.36 , pp. 291-298
    • Choy, E.H.1    Chikanza, I.C.2    Kingsley, G.3    Corrigall, V.4    Panayi, G.S.5
  • 45
    • 0025811883 scopus 로고
    • Autoimmunity to chaperones on the pathogenesis of arthritis and diabetes
    • Cohen, I. R. (1991). Autoimmunity to chaperones on the pathogenesis of arthritis and diabetes. Annu. Rev. Immunol. 9, 567-589.
    • (1991) Annu. Rev. Immunol. , vol.9 , pp. 567-589
    • Cohen, I.R.1
  • 47
    • 0026696991 scopus 로고
    • Angiogenesis and rheumatoid arthritis: Pathogenic and therapeutic implications
    • Colville-Nash, P. R., and Scott, D. L. (1992). Angiogenesis and rheumatoid arthritis: Pathogenic and therapeutic implications. Ann. Rheum. Dis. 51, 919-925.
    • (1992) Ann. Rheum. Dis. , vol.51 , pp. 919-925
    • Colville-Nash, P.R.1    Scott, D.L.2
  • 50
    • 0027978457 scopus 로고
    • Chronic exposure to tumor necrosis factor (TNF) in vitro impairs the activation of T cells through the T cell receptor/CD3 complex: Reversal in vivo by anti-TNF antibodies in patients with rheumatoid arthritis
    • Cope, A. P., Londei, M., Chu, N. R., Cohen, S. B. A., Elliott, M. J., Brennan, F. M., Maini, R. N., and Feldmann, M. (1994). Chronic exposure to tumor necrosis factor (TNF) in vitro impairs the activation of T cells through the T cell receptor/CD3 complex: Reversal in vivo by anti-TNF antibodies in patients with rheumatoid arthritis. J. Clin. Invest. 94, 749-760.
    • (1994) J. Clin. Invest. , vol.94 , pp. 749-760
    • Cope, A.P.1    Londei, M.2    Chu, N.R.3    Cohen, S.B.A.4    Elliott, M.J.5    Brennan, F.M.6    Maini, R.N.7    Feldmann, M.8
  • 53
    • 0015906311 scopus 로고
    • Corticosteroids and infectious disease
    • Dale, D. C, and Petersdorf, R. G. (1973). Corticosteroids and infectious disease. Med. Clin. North Am. 57, 1277-1287.
    • (1973) Med. Clin. North Am. , vol.57 , pp. 1277-1287
    • Dale, D.C.1    Petersdorf, R.G.2
  • 55
    • 0026545719 scopus 로고
    • Localization of interleukin-lα:, type 1 interleukin-1 receptor and interleukin-1 receptor antagonist in the synovial membrane and cartilage/pannus junction in rheumatoid arthritis
    • Deleuran, B. W., Chu, C. Q., Field, M., Brennan, F. M., Katsikis, P., Feldmann, M., and Maini, R. N. (1992). Localization of interleukin-lα:, type 1 interleukin-1 receptor and interleukin-1 receptor antagonist in the synovial membrane and cartilage/pannus junction in rheumatoid arthritis. Br. J. Rheumatol. 31, 801-809.
    • (1992) Br. J. Rheumatol. , vol.31 , pp. 801-809
    • Deleuran, B.W.1    Chu, C.Q.2    Field, M.3    Brennan, F.M.4    Katsikis, P.5    Feldmann, M.6    Maini, R.N.7
  • 58
    • 0023742630 scopus 로고
    • Tumour necrosis factor in synovial exudates
    • Di Giovine, F. S., Nuki, G., and Duff, G. W. (1988). Tumour necrosis factor in synovial exudates. Ann. Rheum. Dis. 47, 768-772.
    • (1988) Ann. Rheum. Dis. , vol.47 , pp. 768-772
    • Di Giovine, F.S.1    Nuki, G.2    Duff, G.W.3
  • 60
    • 0000915343 scopus 로고
    • The production of arthritis in rabbits by an immunological reaction to fibrin
    • Dumonde, D. C, and Glynn, L. E. (1962). The production of arthritis in rabbits by an immunological reaction to fibrin. Br. J. Exp. Pathol. 43, 373-383.
    • (1962) Br. J. Exp. Pathol. , vol.43 , pp. 373-383
    • Dumonde, D.C.1    Glynn, L.E.2
  • 61
    • 0028235297 scopus 로고
    • New directions for biological therapy in rheumatoid arthritis
    • Elliott, M. J., and Maini, R. N. (1994). New directions for biological therapy in rheumatoid arthritis. Int. Arch. Allergy Immunol. 104, 112-125.
    • (1994) Int. Arch. Allergy Immunol. , vol.104 , pp. 112-125
    • Elliott, M.J.1    Maini, R.N.2
  • 64
    • 0028143212 scopus 로고
    • Repeated therapy with monoclonal antibody to tumour necrosis factor a (cA2) in patients with rheumatoid arthritis
    • Elliott, M. J., Maini, R. N., Feldmann, M., Long-Fox, A., Charles, P., Bijl, H., and Woody, J. N. (1994b). Repeated therapy with monoclonal antibody to tumour necrosis factor a (cA2) in patients with rheumatoid arthritis. Lancet 344, 1125-1128.
    • (1994) Lancet , vol.344 , pp. 1125-1128
    • Elliott, M.J.1    Maini, R.N.2    Feldmann, M.3    Long-Fox, A.4    Charles, P.5    Bijl, H.6    Woody, J.N.7
  • 65
    • 0024538157 scopus 로고
    • Factors predicting a poor life prognosis in rheumatoid arthritis: An eight year prospective study
    • Erhardt, C. C, Mumford, P. A., Venables, P. J. W., and Maini, R. N. (1989). Factors predicting a poor life prognosis in rheumatoid arthritis: An eight year prospective study. Ann. Rheum. Dis. 48, 7-13.
    • (1989) Ann. Rheum. Dis. , vol.48 , pp. 7-13
    • Erhardt, C.C.1    Mumford, P.A.2    Venables, P.J.W.3    Maini, R.N.4
  • 66
    • 0029583557 scopus 로고
    • The genotypic distribution of shared-epitope DRB1 alleles suggests a recessive mode of inheritance of the rheumatoid arthritis disease-susceptibility gene
    • Evans, T. I., Han, J., Singh, R., and Moxley, G. (1995). The genotypic distribution of shared-epitope DRB1 alleles suggests a recessive mode of inheritance of the rheumatoid arthritis disease-susceptibility gene. Arthr. Rheum. 38, 1754-1761.
    • (1995) Arthr. Rheum. , vol.38 , pp. 1754-1761
    • Evans, T.I.1    Han, J.2    Singh, R.3    Moxley, G.4
  • 67
    • 0025727898 scopus 로고
    • Transforming growth factor β1 (TGF-β1) induced neutrophil recruitment to synovial tissues: Implications for TGF-β-driven synovial inflammation and hyperplasia
    • Fava, R. A., Olsen, N. J., Postlethwaite, A. E., Broadley, K. N., Davidson, J. M., Nanney, L. B., Lucas, C, and Townes, A. S. (1991). Transforming growth factor β1 (TGF-β1) induced neutrophil recruitment to synovial tissues: Implications for TGF-β-driven synovial inflammation and hyperplasia.J. Exp. Med. 173, 1121-1132.
    • (1991) J. Exp. Med. , vol.173 , pp. 1121-1132
    • Fava, R.A.1    Olsen, N.J.2    Postlethwaite, A.E.3    Broadley, K.N.4    Davidson, J.M.5    Nanney, L.B.6    Lucas, C.7    Townes, A.S.8
  • 68
    • 0028216495 scopus 로고
    • Vascular permeability factor/endothelial growth factor (VPF/VEGF): Accumulation and expression in human synovial fluids and rheumatoid synovial tissue
    • Fava, R. A., Olsen, N. J., Spencer-Green, G., Yeo, K.-T., Yeo, T.-K., Berse, B., Jackman, R. W. Senger, D. R., Dvorak, H. F., and Brown, L. F. (1994). Vascular permeability factor/endothelial growth factor (VPF/VEGF): Accumulation and expression in human synovial fluids and rheumatoid synovial tissue. J. Exp. Med. 180, 334-346.
    • (1994) J. Exp. Med. , vol.180 , pp. 334-346
    • Fava, R.A.1    Olsen, N.J.2    Spencer-Green, G.3    Yeo, K.-T.4    Yeo, T.-K.5    Berse, B.6    Jackman, R.W.7    Senger, D.R.8    Dvorak, H.F.9    Brown, L.F.10
  • 71
    • 0017529293 scopus 로고
    • The effect of synovial tissue on the breakdown of articular cartilage in organ culture
    • Fell, H. B., and Jubb, R. W. (1977). The effect of synovial tissue on the breakdown of articular cartilage in organ culture. Arthr. Rheum. 20, 1359-1371.
    • (1977) Arthr. Rheum. , vol.20 , pp. 1359-1371
    • Fell, H.B.1    Jubb, R.W.2
  • 72
    • 0026505773 scopus 로고
    • Molecular and biological properties of the vascular endothelial growth factor family of proteins
    • Ferrara, N., Houck, K., Jakeman, L., and Leung, D. W. (1992). Molecular and biological properties of the vascular endothelial growth factor family of proteins. Endocrinol. Rev. 13, 18-32.
    • (1992) Endocrinol. Rev. , vol.13 , pp. 18-32
    • Ferrara, N.1    Houck, K.2    Jakeman, L.3    Leung, D.W.4
  • 73
    • 0025348745 scopus 로고
    • How important are T cells in chronic rheumatoid synovitis?
    • Firestein, G. S., and Zvaifler, N. J. (1990). How important are T cells in chronic rheumatoid synovitis? Arthr. Rheum. 33, 768-773.
    • (1990) Arthr. Rheum. , vol.33 , pp. 768-773
    • Firestein, G.S.1    Zvaifler, N.J.2
  • 74
    • 0024240494 scopus 로고
    • Cytokines in chronic inflammatory arthritis. I. Failure to detect T cell lymphokines (interleukin 2 and interleukin 3) and presence of macrophage colony-stimulating factor (CSF-1) and a novel mast cell growth factor in rheumatoid synovitis
    • Firestein, G. S., Xu, W.-D., Townsend, K., Broide, D., Alvaro-Gracia, J., Glasebrook, A., and Zvaifler, N. J. (1988). Cytokines in chronic inflammatory arthritis. I. Failure to detect T cell lymphokines (interleukin 2 and interleukin 3) and presence of macrophage colony-stimulating factor (CSF-1) and a novel mast cell growth factor in rheumatoid synovitis. Exp. Med. 168, 1573-1586.
    • (1988) Exp. Med. , vol.168 , pp. 1573-1586
    • Firestein, G.S.1    Xu, W.-D.2    Townsend, K.3    Broide, D.4    Alvaro-Gracia, J.5    Glasebrook, A.6    Zvaifler, N.J.7
  • 75
    • 0026721695 scopus 로고
    • IL-1 receptor antagonist protein production and gene expression in rheumatoid arthritis and osteoarthritis synovium
    • Firestein, G. S., Berger, A. E., Tracey, D. E., Chosay, J. G., Chapman, D. L., Paine, M. M., Yu, C, and Zvaifler, N. J. (1992). IL-1 receptor antagonist protein production and gene expression in rheumatoid arthritis and osteoarthritis synovium. J. Immunol. 149, 1054-1062.
    • (1992) J. Immunol. , vol.149 , pp. 1054-1062
    • Firestein, G.S.1    Berger, A.E.2    Tracey, D.E.3    Chosay, J.G.4    Chapman, D.L.5    Paine, M.M.6    Yu, C.7    Zvaifler, N.J.8
  • 76
    • 0027406403 scopus 로고
    • Influence of an anti-tumor necrosis factor monoclonal antibody on cytokine levels in patients with sepsis. The CB0006 Sepsis Syndrome Study Group [see comments]
    • Fisher, C, Jr., Opal, S. M., Dhainaut, J. F., Stephens, S., Zimmerman, J. L., Nightingale, P., Harris, S. J., Schein, R. M., Panacek, E. A., Vincent, J. L., et al. (1993). Influence of an anti-tumor necrosis factor monoclonal antibody on cytokine levels in patients with sepsis. The CB0006 Sepsis Syndrome Study Group [see comments]. Crit. Care Med. 21, 318-327.
    • (1993) Crit. Care Med. , vol.21 , pp. 318-327
    • Fisher, C.1    Opal, S.M.2    Dhainaut, J.F.3    Stephens, S.4    Zimmerman, J.L.5    Nightingale, P.6    Harris, S.J.7    Schein, R.M.8    Panacek, E.A.9    Vincent, J.L.10
  • 78
    • 0020323211 scopus 로고
    • Interleukin-1 activity in the synovial fluid of patients with rheumatoid arthritis
    • Fontana, A., Hentgartner, H., Fehr, K., Grab, P. J., and Cohen, G. (1982). Interleukin-1 activity in the synovial fluid of patients with rheumatoid arthritis. Rheumatol. Int. 2,49-56.
    • (1982) Rheumatol. Int. , vol.2 , pp. 49-56
    • Fontana, A.1    Hentgartner, H.2    Fehr, K.3    Grab, P.J.4    Cohen, G.5
  • 80
    • 0028321401 scopus 로고
    • Problems and paradigms in joint pathology
    • Gardner, D. L. (1994). Problems and paradigms in joint pathology. J. Anat. 184, 465-476.
    • (1994) J. Anat. , vol.184 , pp. 465-476
    • Gardner, D.L.1
  • 83
    • 0001550784 scopus 로고
    • Clinical features: Early, progressive and late disease
    • J. H. Klippel and A. Dieppe, Eds.), Section 3,. Mosby, London
    • Gordon, D. A., and Hastings, D. E. (1994). Clinical features: Early, progressive and late disease. In "Rheumatology" (J. H. Klippel and P. A. Dieppe, Eds.), Section 3, pp. 4.1-4.14. Mosby, London.
    • (1994) Rheumatology , pp. 41-414
    • Gordon, D.A.1    Hastings, D.E.2
  • 84
    • 0021069905 scopus 로고
    • An interleukin-1 like factor stimulates bone resorption in vitro
    • Gowen, M., Wood, D. D., Ihrie, E. J., McGuire, M. K. B., and Russell, R. G. (1983). An interleukin-1 like factor stimulates bone resorption in vitro. Nature 306, 378-380.
    • (1983) Nature , vol.306 , pp. 378-380
    • Gowen, M.1    Wood, D.D.2    Ihrie, E.J.3    McGuire, M.K.B.4    Russell, R.G.5
  • 86
    • 0023500817 scopus 로고
    • The shared epitope hypothesis. An approach to understanding the molecular genetics of susceptibility to Rheumatoid arthritis
    • Gregersen, P. K., Silver, J., and Winchester, R. J. (1987). The shared epitope hypothesis. An approach to understanding the molecular genetics of susceptibility to Rheumatoid arthritis. Arthr. Rheum. 30, 1205-1213.
    • (1987) Arthr. Rheum. , vol.30 , pp. 1205-1213
    • Gregersen, P.K.1    Silver, J.2    Winchester, R.J.3
  • 88
    • 0025098538 scopus 로고
    • Endotoxin-responsive sequences control cachectin/tumor necrosis factor biosynthesis at the translational level
    • Published erratum J. Exp. Med. 171(3), 971-972, 1990
    • Han, J., Brown, T., and Beutler, B. (1990). Endotoxin-responsive sequences control cachectin/tumor necrosis factor biosynthesis at the translational level.J. Exp. Med. 171,465-475. [Published erratum appears inJ. Exp. Med. 171(3), 971-972, 1990]
    • (1990) J. Exp. Med. , vol.171 , pp. 465-475
    • Han, J.1    Brown, T.2    Beutler, B.3
  • 89
    • 0001668155 scopus 로고    scopus 로고
    • Safety and efficacy of TNF neutralization by lenercept in patients with rheumatoid arthritis exposed to a single dose
    • abstract 1291
    • Hasler, F., van de Putte, L., Dumont, E., Kneer, J., Bock, J., Dickenson, S., Lesslauer, W., and Van de Auwera, P. (1996). Safety and efficacy of TNF neutralization by lenercept in patients with rheumatoid arthritis exposed to a single dose. Arth. Rheum. 39, S243. [abstract 1291]
    • (1996) Arth. Rheum. , vol.39 , pp. S243
    • Hasler, F.1    van de Putte, L.2    Dumont, E.3    Kneer, J.4    Bock, J.5    Dickenson, S.6    Lesslauer, W.7    van de Auwera, P.8
  • 90
    • 0001668155 scopus 로고    scopus 로고
    • Chronic TNF neutralization (up to 1 year) by lenercept (TNFR 55 IgG 1, Ro 45-2081) in patients with rheumatoid arthritis: Results for open label extension of a double-blind single-dose phase I study
    • abstract 1292
    • Hasler, F., van de Putte, L., Baudin, M., Lodin, E., Durrwell, L., McAuliffe, T., and van de Auwera, P. (1996). Chronic TNF neutralization (up to 1 year) by lenercept (TNFR 55 IgG 1, Ro 45-2081) in patients with rheumatoid arthritis: Results for open label extension of a double-blind single-dose phase I study. Arth. Rheum. 39, S243. [abstract 1292].
    • (1996) Arth. Rheum. , vol.39 , pp. S243
    • Hasler, F.1    van de Putte, L.2    Baudin, M.3    Lodin, E.4    Durrwell, L.5    McAuliffe, T.6    van de Auwera, P.7
  • 91
    • 0024825945 scopus 로고
    • Demonstration of a new anti-nuclear antibody (anti-RA 33) that is highly specific for rheumatoid arthritis
    • Hassfeld, W., Steiner, G., Hartmuth, K., Kolarz, G., Scherak, O., Grainger, W., Thumb, N., and Smolen, J. S. (1989). Demonstration of a new anti-nuclear antibody (anti-RA 33) that is highly specific for rheumatoid arthritis. Arthr. Rheum. 32, 1515-1520.
    • (1989) Arthr. Rheum. , vol.32 , pp. 1515-1520
    • Hassfeld, W.1    Steiner, G.2    Hartmuth, K.3    Kolarz, G.4    Scherak, O.5    Grainger, W.6    Thumb, N.7    Smolen, J.S.8
  • 92
    • 0025939257 scopus 로고
    • Expression of granulocyte-macrophage colony-stimulating factor (GM-CSF) in rheumatoid arthritis: Regulation by tumour necrosis factor-α
    • Haworth, C, Brennan, F. M., Chantry, D., Turner, M., Maini, R. N., and Feldmann, M. (1991). Expression of granulocyte-macrophage colony-stimulating factor (GM-CSF) in rheumatoid arthritis: Regulation by tumour necrosis factor-α. Eur. J. Immunol. 21,2575-2579.
    • (1991) Eur. J. Immunol. , vol.21 , pp. 2575-2579
    • Haworth, C.1    Brennan, F.M.2    Chantry, D.3    Turner, M.4    Maini, R.N.5    Feldmann, M.6
  • 93
    • 0026748345 scopus 로고
    • Recombinant glycosylated human interleukin-6 accelerates peripheral blood platelet count recovery in radiation-induced bone marrow depression in baboons
    • Herodin, F., Mestries, J. C, Janodet, D., Martin, S., Mathieu, J., Gascon, M. P., Pernin, M. O., and Ythier, A. (1992). Recombinant glycosylated human interleukin-6 accelerates peripheral blood platelet count recovery in radiation-induced bone marrow depression in baboons. Blood 80, 688-695.
    • (1992) Blood , vol.80 , pp. 688-695
    • Herodin, F.1    Mestries, J.C.2    Janodet, D.3    Martin, S.4    Mathieu, J.5    Gascon, M.P.6    Pernin, M.O.7    Ythier, A.8
  • 94
    • 0027960243 scopus 로고
    • The effects of selective inhibitors of matrix metalloproteinases (MMPs) on bone resorption and the identification of MMPs and TIMP-1 in isolated osteoclasts
    • Hill, P. A., Murphy, G., Docherty, A. J., Hembry, R. M., Millican, T. A., Reynolds, J. J., and Meikle, M. C. (1994). The effects of selective inhibitors of matrix metalloproteinases (MMPs) on bone resorption and the identification of MMPs and TIMP-1 in isolated osteoclasts. J. Cell Sci. 107, 3055-3064.
    • (1994) J. Cell Sci. , vol.107 , pp. 3055-3064
    • Hill, P.A.1    Murphy, G.2    Docherty, A.J.3    Hembry, R.M.4    Millican, T.A.5    Reynolds, J.J.6    Meikle, M.C.7
  • 97
    • 0023729525 scopus 로고
    • Immunogenetics of type II collagen autoimmunity and susceptibility to collagen arthritis
    • Holmdahl, R., Tarkowski, A., and Jonsson, R. (1988). Immunogenetics of type II collagen autoimmunity and susceptibility to collagen arthritis. Immunology 65, 305-310.
    • (1988) Immunology , vol.65 , pp. 305-310
    • Holmdahl, R.1    Tarkowski, A.2    Jonsson, R.3
  • 98
    • 0023952058 scopus 로고
    • Cytokines in synovial fluid. I. The presence of biologically active and immunoreactive IL-1
    • Hopkins, S. J., Humphreys, M., and Jayson, M. I. (1988). Cytokines in synovial fluid. I. The presence of biologically active and immunoreactive IL-1. Clin. Exp. Immunol. 72, 422-427.
    • (1988) Clin. Exp. Immunol. , vol.72 , pp. 422-427
    • Hopkins, S.J.1    Humphreys, M.2    Jayson, M.I.3
  • 99
    • 0025980476 scopus 로고
    • Treatment of rheumatoid arthritis with an anti-CD4 monoclonal antibody
    • Horneff, G., Burmester, G. R., Emmrieh, F., and Kalden, J. R. (1991). Treatment of rheumatoid arthritis with an anti-CD4 monoclonal antibody. Arthr. Rheum. 34,129-140.
    • (1991) Arthr. Rheum. , vol.34 , pp. 129-140
    • Horneff, G.1    Burmester, G.R.2    Emmrieh, F.3    Kalden, J.R.4
  • 100
    • 0028093436 scopus 로고
    • Expression of the chemokine superfamily in rheumatoid arthritis
    • Hosaka, S., Akshoshi, T., Wada, C, and Kondo, H. (1994). Expression of the chemokine superfamily in rheumatoid arthritis. Clin. Exp. Immunol. 97, 451-457.
    • (1994) Clin. Exp. Immunol. , vol.97 , pp. 451-457
    • Hosaka, S.1    Akshoshi, T.2    Wada, C.3    Kondo, H.4
  • 102
    • 0028081880 scopus 로고
    • Continuous administration of anti-interleuldn 10 antibodies delays onset of autoimmunity in NZB/W Fl mice
    • Ishida, H., Muchamuel, T., Sakaguchi, S., Andrade, S., Menon, S., and Howard, M. (1994). Continuous administration of anti-interleuldn 10 antibodies delays onset of autoimmunity in NZB/W Fl mice. J. Exp. Med. 179, 305-310.
    • (1994) J. Exp. Med. , vol.179 , pp. 305-310
    • Ishida, H.1    Muchamuel, T.2    Sakaguchi, S.3    Andrade, S.4    Menon, S.5    Howard, M.6
  • 103
    • 0028144871 scopus 로고
    • The role of tumour necrosis factor-alpha and IL-1 in polymorphonuclear leucocyte and T lymphocyte recruitment to joint inflammation in adjuvant arthritis
    • Issekutz, A. C, Meager, A., Otterness, I., and Isskeutz, T. B. (1994). The role of tumour necrosis factor-alpha and IL-1 in polymorphonuclear leucocyte and T lymphocyte recruitment to joint inflammation in adjuvant arthritis. Clin. Exp. Immunol. 97, 26-32.
    • (1994) Clin. Exp. Immunol. , vol.97 , pp. 26-32
    • Issekutz, A.C.1    Meager, A.2    Otterness, I.3    Isskeutz, T.B.4
  • 104
    • 0023874728 scopus 로고
    • Tumour necrosis factor-alpha in murine autoimmune "lupus" nephritis
    • Jacob, C. O., and McDevitt, H. O. (1988). Tumour necrosis factor-alpha in murine autoimmune "lupus" nephritis. Nature 331, 356-358.
    • (1988) Nature , vol.331 , pp. 356-358
    • Jacob, C.O.1    McDevitt, H.O.2
  • 105
    • 0025016823 scopus 로고
    • Heritable major histocompatibility complex class II-associated differences in production of tumor necrosis factor α: Relevance to genetic predisposition to systemic lupus erythematosus
    • Jacob, C. O., Fronek, Z., Lewis, G. D., Koo, M., Hansen, J. A., and McDevitt, H. O. (1990). Heritable major histocompatibility complex class II-associated differences in production of tumor necrosis factor α: Relevance to genetic predisposition to systemic lupus erythematosus. Proc. Natl. Acad. Sci. USA 87, 1233-1237.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 1233-1237
    • Jacob, C.O.1    Fronek, Z.2    Lewis, G.D.3    Koo, M.4    Hansen, J.A.5    McDevitt, H.O.6
  • 106
    • 0024409917 scopus 로고
    • Chronic exposure to tumor necrosis factor in vivo preferentially inhibits erythropoiesis in nude mice
    • Johnson, R. A., Waddelow, T. A., Caro, J., Oliff, A., and Roodman, G. D. (1989). Chronic exposure to tumor necrosis factor in vivo preferentially inhibits erythropoiesis in nude mice. Blood 74, 130-138.
    • (1989) Blood , vol.74 , pp. 130-138
    • Johnson, R.A.1    Waddelow, T.A.2    Caro, J.3    Oliff, A.4    Roodman, G.D.5
  • 107
    • 0025275703 scopus 로고
    • Constitutive production of interleukin-6 and immunologic features in cardiac myxomas
    • Jourdan, M., Bataille, R., Seguin, J., Zhang, X. G., Chaptal, P. A., and Klein, B. (1990). Constitutive production of interleukin-6 and immunologic features in cardiac myxomas. Arthr. Rheum. 33, 398-402.
    • (1990) Arthr. Rheum. , vol.33 , pp. 398-402
    • Jourdan, M.1    Bataille, R.2    Seguin, J.3    Zhang, X.G.4    Chaptal, P.A.5    Klein, B.6
  • 108
    • 0026538903 scopus 로고
    • Experimental animal models resembling rheumatoid arthritis
    • Kaklamanis, P. M. (1992). Experimental animal models resembling rheumatoid arthritis. Clin. Rheum. 11, 41-47.
    • (1992) Clin. Rheum. , vol.11 , pp. 41-47
    • Kaklamanis, P.M.1
  • 109
    • 0028226993 scopus 로고
    • Immunoregulatoryrole of interleukin 10 (IL-10) in rheumatoid arthritis
    • Katsikis, P., Chu, C. Q., Brennan, F. M., Maini, R. N., and Feldmann, M. (1994). Immunoregulatoryrole of interleukin 10 (IL-10) in rheumatoid arthritis.J. Exp. Med. 179,1517-1527.
    • (1994) J. Exp. Med. , vol.179 , pp. 1517-1527
    • Katsikis, P.1    Chu, C.Q.2    Brennan, F.M.3    Maini, R.N.4    Feldmann, M.5
  • 111
    • 0026039673 scopus 로고
    • Transgenic mice expressing human tumour necrosis factor: A predictive genetic model of arthritis
    • Keffer, J., Probert, L., Cazlaris, H., Georgopoulos, S., Kaslaris, E., Kioussis, D., and Kollias, G. (1991). Transgenic mice expressing human tumour necrosis factor: A predictive genetic model of arthritis. EMBO J. 10, 4025-4031.
    • (1991) EMBO J , vol.10 , pp. 4025-4031
    • Keffer, J.1    Probert, L.2    Cazlaris, H.3    Georgopoulos, S.4    Kaslaris, E.5    Kioussis, D.6    Kollias, G.7
  • 112
    • 0023521629 scopus 로고
    • Lymphotoxin is an important T cell derived growth factor for human B cells
    • Kehrl, J. H., Alvarez-Mon, M., Delsing, G. A., and Fauci, A. S. (1987a). Lymphotoxin is an important T cell derived growth factor for human B cells. Science 238, 1144-1146.
    • (1987) Science , vol.238 , pp. 1144-1146
    • Kehrl, J.H.1    Alvarez-Mon, M.2    Delsing, G.A.3    Fauci, A.S.4
  • 113
    • 0023404194 scopus 로고
    • Effects of tumor necrosis factor a on mitogen-activated human B cells
    • Kehrl, J. H., Miller, A., and Fauci, A. S. (1987b). Effects of tumor necrosis factor a on mitogen-activated human B cells. J. Exp. Med. 166, 786-791.
    • (1987) J. Exp. Med. , vol.166 , pp. 786-791
    • Kehrl, J.H.1    Miller, A.2    Fauci, A.S.3
  • 114
    • 0024850341 scopus 로고
    • Pathogenesis of lentivirus-induced arthritis: A review
    • Kennedy-Stoskopf, S. (1989). Pathogenesis of lentivirus-induced arthritis: A review. Rheumatol. Int. 9, 129-136.
    • (1989) Rheumatol. Int. , vol.9 , pp. 129-136
    • Kennedy-Stoskopf, S.1
  • 115
    • 0025572237 scopus 로고
    • Autoimmunity to collagen II and myelin basic protein: Comparative studies in humans and rodents
    • Klareskog, L., and Olsson, T. (1990). Autoimmunity to collagen II and myelin basic protein: Comparative studies in humans and rodents. Immunol. Rev. 118, 285-310.
    • (1990) Immunol. Rev. , vol.118 , pp. 285-310
    • Klareskog, L.1    Olsson, T.2
  • 117
    • 0016703280 scopus 로고
    • Electron microscopic studies of the cartilage-pannus junction in rheumatoid arthritis
    • Kobayashi, I., and Ziff, M. (1975). Electron microscopic studies of the cartilage-pannus junction in rheumatoid arthritis. Arthr. Rheum. 18, 475-483.
    • (1975) Arthr. Rheum. , vol.18 , pp. 475-483
    • Kobayashi, I.1    Ziff, M.2
  • 118
    • 0025736324 scopus 로고
    • Immunolocalization of endothelial and leukocyte adhesion molecules in human rheumatoid and osteoarthritic synovial tissues
    • Koch, A. E., Burrows, J. C., Haines, G. K., Carlos, T. M., Harlan, J. M., and Leibovich, S. J. (1991). Immunolocalization of endothelial and leukocyte adhesion molecules in human rheumatoid and osteoarthritic synovial tissues. Lab. Invest. 64, 313-320.
    • (1991) Lab. Invest. , vol.64 , pp. 313-320
    • Koch, A.E.1    Burrows, J.C.2    Haines, G.K.3    Carlos, T.M.4    Harlan, J.M.5    Leibovich, S.J.6
  • 120
    • 0028199835 scopus 로고
    • Vascular endothelial growth factor: A cytokine-modulating endothelial function in rheumatoid arthritis
    • Koch, A. E., Harlow, L. A., Haines, G. K., Amento, E. P., Unemori, E. N., Wong, W. L., Pope, R. M., and Ferrara, N. (1994a). Vascular endothelial growth factor: A cytokine-modulating endothelial function in rheumatoid arthritis. J. Immunol. 152, 4149-4156.
    • (1994) J. Immunol. , vol.152 , pp. 4149-4156
    • Koch, A.E.1    Harlow, L.A.2    Haines, G.K.3    Amento, E.P.4    Unemori, E.N.5    Wong, W.L.6    Pope, R.M.7    Ferrara, N.8
  • 122
    • 0029127230 scopus 로고
    • Angiogenesis mediated by soluble forms of E-selectin and vascular cells adhesion molecule-1
    • Koch, A. E., Halloran, M. M., Haskell, C. J., Shah, M. R., and Polverini, P. J. (1995). Angiogenesis mediated by soluble forms of E-selectin and vascular cells adhesion molecule-1. Nature 376, 517-519.
    • (1995) Nature , vol.376 , pp. 517-519
    • Koch, A.E.1    Halloran, M.M.2    Haskell, C.J.3    Shah, M.R.4    Polverini, P.J.5
  • 123
    • 0024353803 scopus 로고
    • Transforming growth factor-beta production by synovial tissues from rheumatoid patients and streptococcal cell wall arthritis rats. Studies on secretion by synovial fibroblast-like cells and immunohistological localisation
    • Lafyatis, R., Thomson, N. L., Remmers, E. R., Flanders, K. C, Roche, N. S., and Kim, S. J. (1989). Transforming growth factor-beta production by synovial tissues from rheumatoid patients and streptococcal cell wall arthritis rats. Studies on secretion by synovial fibroblast-like cells and immunohistological localisation. J. Immunol. 143, 1142-1148.
    • (1989) J. Immunol. , vol.143 , pp. 1142-1148
    • Lafyatis, R.1    Thomson, N.L.2    Remmers, E.R.3    Flanders, K.C.4    Roche, N.S.5    Kim, S.J.6
  • 124
    • 0023696096 scopus 로고
    • Elevated levels of circulating cachetin/tumor necrosis factor in patients with acquired immunodeficiency syndrome
    • Lahdevirta, J., Maury, C. P. J., Teppo, A.-M., and Repo, H. (1988). Elevated levels of circulating cachetin/tumor necrosis factor in patients with acquired immunodeficiency syndrome. Am. J. Med. 85, 289-291.
    • (1988) Am. J. Med. , vol.85 , pp. 289-291
    • Lahdevirta, J.1    Maury, C.P.J.2    Teppo, A.-M.3    Repo, H.4
  • 125
    • 0029559439 scopus 로고
    • Role of tumor necrosis factor-a in the regulation of activated synovial T cell growth: Down-regulation of synovial T cells in rheumatoid arthritis patients
    • Lai, N.-S., Lan, J.-L., Yu, C.-L., and Lin, R.-H. (1995). Role of tumor necrosis factor-a in the regulation of activated synovial T cell growth: Down-regulation of synovial T cells in rheumatoid arthritis patients. Eur. J. Immunol. 25, 3243-3248.
    • (1995) Eur. J. Immunol. , vol.25 , pp. 3243-3248
    • Lai, N.-S.1    Lan, J.-L.2    Yu, C.-L.3    Lin, R.-H.4
  • 126
    • 0014822605 scopus 로고
    • Rheumatoid arthritis: Nature of nurture?
    • Laurence, J. S. (1970). Rheumatoid arthritis: Nature of nurture? Ann. Rheum. Dis. 29, 357-369.
    • (1970) Ann. Rheum. Dis. , vol.29 , pp. 357-369
    • Laurence, J.S.1
  • 129
    • 0028200189 scopus 로고
    • Lymphoma in a patient under low dose methotrexate for rheumatoid arthritis: A new case
    • LeGoff, P., Koreichi, A., Saraux, A., and Baron, D. (1994). Lymphoma in a patient under low dose methotrexate for rheumatoid arthritis: A new case. Rev. Rheum. 61, 330-331.
    • (1994) Rev. Rheum. , vol.61 , pp. 330-331
    • LeGoff, P.1    Koreichi, A.2    Saraux, A.3    Baron, D.4
  • 130
    • 0024818355 scopus 로고
    • Vascular endothelial growth factor is a secreted angiogenic mitogen
    • Leung, D. W., Cachianes, G., Kuang, W. J., Goeddel, D. V., and Ferrara, N. (1989). Vascular endothelial growth factor is a secreted angiogenic mitogen. Science 246, 1306-1309.
    • (1989) Science , vol.246 , pp. 1306-1309
    • Leung, D.W.1    Cachianes, G.2    Kuang, W.J.3    Goeddel, D.V.4    Ferrara, N.5
  • 133
    • 0028890866 scopus 로고
    • Thl and Th2 CD4+ T cells in the pathogenesis of organ-specific autoimmune diseases
    • Liblau, R. S., Singer, S. M., and McDevitt, H. O. (1995). Thl and Th2 CD4+ T cells in the pathogenesis of organ-specific autoimmune diseases. Immunol. Today 16, 34-38.
    • (1995) Immunol. Today , vol.16 , pp. 34-38
    • Liblau, R.S.1    Singer, S.M.2    McDevitt, H.O.3
  • 134
    • 0024310608 scopus 로고
    • The control of antibody production by immunomodulatory molecules
    • Lipsky, P. E. (1989). The control of antibody production by immunomodulatory molecules. Arthr. Rheum. 32, 1345-1355.
    • (1989) Arthr. Rheum. , vol.32 , pp. 1345-1355
    • Lipsky, P.E.1
  • 135
    • 0038329656 scopus 로고
    • Attempts at determinant-specific antibody blockade of macrophage presentation
    • E. R. Unanue and A. S. Rosenthal, Eds.),. Academic Press, San Diego
    • Loblay, R. H., Schroer, J., and Rosenthal, A. S. (1980). Attempts at determinant-specific antibody blockade of macrophage presentation. In "Macrophage Regulation of Immunity" (E. R. Unanue and A. S. Rosenthal, Eds.), pp. 87. Academic Press, San Diego.
    • (1980) Macrophage Regulation of Immunity , pp. 87
    • Loblay, R.H.1    Schroer, J.2    Rosenthal, A.S.3
  • 137
    • 0025269050 scopus 로고
    • Molecular cloning and expression of the human 55 kd tumor necrosis factor receptor
    • Loetscher, H., Pan, Y. C., Lahm, H. W., Gentz, R., Brockhaus, M., Tabuchi, H., and Lesslauer, W. (1990). Molecular cloning and expression of the human 55 kd tumor necrosis factor receptor. Cell 61, 351-359.
    • (1990) Cell , vol.61 , pp. 351-359
    • Loetscher, H.1    Pan, Y.C.2    Lahm, H.W.3    Gentz, R.4    Brockhaus, M.5    Tabuchi, H.6    Lesslauer, W.7
  • 139
    • 0022543062 scopus 로고
    • Basis for defective responses of rheumatoid synovial fluid lymphocytes to anti-CD3 (T3) antibodies
    • Lotz, M., Tsoukas, C. D., Robinson, C. A., Dinarello, C. A., Carson, D. A., and Vaughan, J. H. (1986). Basis for defective responses of rheumatoid synovial fluid lymphocytes to anti-CD3 (T3) antibodies. J. Clin. Invest. 78, 713-721.
    • (1986) J. Clin. Invest. , vol.78 , pp. 713-721
    • Lotz, M.1    Tsoukas, C.D.2    Robinson, C.A.3    Dinarello, C.A.4    Carson, D.A.5    Vaughan, J.H.6
  • 140
    • 0025283586 scopus 로고
    • Transforming growth factor-/3 and cellular immune responses in synovial fluids
    • Lotz, M., Kekow, J., and Carson, D. A. (1990). Transforming growth factor-/3 and cellular immune responses in synovial fluids. J. Immunol. 144, 4189-4194.
    • (1990) J. Immunol. , vol.144 , pp. 4189-4194
    • Lotz, M.1    Kekow, J.2    Carson, D.A.3
  • 141
    • 0028038782 scopus 로고
    • Inflammatory granuloma formation is mediated by TNF-alpha-inducible intercellular adhesion molecule-1
    • Lukacs, N. W., Chensue, S. W., Strieter, R. M., Warmington, K., and Kunkel, S. L. (1994). Inflammatory granuloma formation is mediated by TNF-alpha-inducible intercellular adhesion molecule-1. J. Immunol. 152, 5883-5889.
    • (1994) J. Immunol. , vol.152 , pp. 5883-5889
    • Lukacs, N.W.1    Chensue, S.W.2    Strieter, R.M.3    Warmington, K.4    Kunkel, S.L.5
  • 142
    • 0025333699 scopus 로고
    • Tumour necrosis factor-alpha and interferon-gamma production measured at the single cell level in normal and inflamed human intestine
    • MacDonald, T. T., Hutchings, P., Choy, M. Y., Murch, S., and Cooke, A. (1990). Tumour necrosis factor-alpha and interferon-gamma production measured at the single cell level in normal and inflamed human intestine. Clin. Exp. Immunol. 81, 301-305.
    • (1990) Clin. Exp. Immunol. , vol.81 , pp. 301-305
    • MacDonald, T.T.1    Hutchings, P.2    Choy, M.Y.3    Murch, S.4    Cooke, A.5
  • 144
    • 6444235059 scopus 로고
    • An analysis of the relative contribution of genetic and environmental factors to rheumatoid arthritis susceptibility
    • Macgregor, A. J., and Silman, A. (1994). An analysis of the relative contribution of genetic and environmental factors to rheumatoid arthritis susceptibility. Arihr. Rheum. 37, S169.
    • (1994) Arihr. Rheum. , vol.37 , pp. S169
    • Macgregor, A.J.1    Silman, A.2
  • 145
    • 0028596320 scopus 로고
    • Immunological intervention reveals reciprocal roles for TNFα and IL-10 in rheumatoid arthritis and SLE
    • Maini, R. N., Elliott, M. J., Charles, P. J., and Feldmann, M. (1994). Immunological intervention reveals reciprocal roles for TNFα and IL-10 in rheumatoid arthritis and SLE. Springer Sem. Immunopathol. 16, 327-336.
    • (1994) Springer Sem. Immunopathol. , vol.16 , pp. 327-336
    • Maini, R.N.1    Elliott, M.J.2    Charles, P.J.3    Feldmann, M.4
  • 146
    • 0002291221 scopus 로고
    • Aetiopathogenesis of rheumatoid arthritis
    • B. Henderson, J. C. W. Edwards, and E. R. Pettipher, Eds.),. Academic Press, San Diego
    • Maini, R. N., Chu, C. Q., and Feldmann, M. (1995a). Aetiopathogenesis of rheumatoid arthritis. In "Mechanisms and Models in Rheumatoid Arthritis" (B. Henderson, J. C. W. Edwards, and E. R. Pettipher, Eds.), pp. 25-46. Academic Press, San Diego.
    • (1995) Mechanisms and Models in Rheumatoid Arthritis , pp. 25-46
    • Maini, R.N.1    Chu, C.Q.2    Feldmann, M.3
  • 149
    • 0027190338 scopus 로고
    • Levels of synovial fluid interleukin-1 receptor antagonist in rheumatoid arthritis and other arthropathies
    • Malyak, M., Swaney, R. E., and Arend, W. P. (1993). Levels of synovial fluid interleukin-1 receptor antagonist in rheumatoid arthritis and other arthropathies. Arthr. Rheum. 36, 781-789.
    • (1993) Arthr. Rheum. , vol.36 , pp. 781-789
    • Malyak, M.1    Swaney, R.E.2    Arend, W.P.3
  • 150
    • 0001607738 scopus 로고
    • Development and validation of an endoscopic index of the severity for Crohn's disease: A prospective multicentre study. Groupe d'etudes therapeutiques des Affections inflammatoires du tube digestif (GETAID)
    • Mary, J. Y., and Modigliani, R. (1989). Development and validation of an endoscopic index of the severity for Crohn's disease: A prospective multicentre study. Groupe d'Etudes Therapeutiques des Affections Inflammatoires du Tube Digestif (GETAID). Gut 30, 983-989.
    • (1989) Gut , vol.30 , pp. 983-989
    • Mary, J.Y.1    Modigliani, R.2
  • 151
    • 0028001431 scopus 로고
    • Incidence of rheumatoid arthritis: Do the observed age-sex interaction patterns support a role of androgenic-anabolic steroid deficiency in its padiogenesis?
    • Masi, A. T. (1994). Incidence of rheumatoid arthritis: Do the observed age-sex interaction patterns support a role of androgenic-anabolic steroid deficiency in its padiogenesis? Br. J. Rheumatol. 33, 697.
    • (1994) Br. J. Rheumatol. , vol.33 , pp. 697
    • Masi, A.T.1
  • 152
    • 0029143898 scopus 로고
    • Treatment of active refractory rheumatoid arthritis with humanized monoclonal antibody CAMPATH-1H administered by daily subcutaneous injection
    • Matteson, E. L., Yocum, D. E., St. Clair, E. W., Achkar, A. A., Thakor, M. S., Jacobs, M. R., Hays, A. E., Heitman, C. K., and Johnston, J. M. (1995). Treatment of active refractory rheumatoid arthritis with humanized monoclonal antibody CAMPATH-1H administered by daily subcutaneous injection. Arthr. Rheum. 38, 1187-1193.
    • (1995) Arthr. Rheum. , vol.38 , pp. 1187-1193
    • Matteson, E.L.1    Yocum, D.E.2    St. Clair, E.W.3    Achkar, A.A.4    Thakor, M.S.5    Jacobs, M.R.6    Hays, A.E.7    Heitman, C.K.8    Johnston, J.M.9
  • 154
    • 0028967045 scopus 로고
    • Fibrinogen in ischaemic heart disease
    • Meade, T. W. (1995). Fibrinogen in ischaemic heart disease. Eur. Heart J. 16(Suppl. A), 31-35.
    • (1995) Eur. Heart J. , vol.16 , pp. 31-35
    • Meade, T.W.1
  • 155
    • 0024352308 scopus 로고
    • Treatment of the anemia of rheumatoid arthritis with recombinant human erythropoietin: Clinical and in vitro studies
    • Means, R. T. J., Olsen, N. J., Krantz, S. B., Dessypris, E. N., Graber, S. E., Stone, W. J., O'Neil, V. L., and Pincus, T. (1989). Treatment of the anemia of rheumatoid arthritis with recombinant human erythropoietin: Clinical and in vitro studies. Arthr. Rheum. 32, 638-642.
    • (1989) Arthr. Rheum. , vol.32 , pp. 638-642
    • Means, R.T.J.1    Olsen, N.J.2    Krantz, S.B.3    Dessypris, E.N.4    Graber, S.E.5    Stone, W.J.6    O'Neil, V.L.7    Pincus, T.8
  • 157
    • 0023197152 scopus 로고
    • Immunity to cartilage proteoglycans in BALB/c mice with progressive polyarthritis and ankylosing spondylitis induced by injection of human cartilage proteoglycan
    • Mikecz, K., Giant, T. T., and Poole, A. R. (1987). Immunity to cartilage proteoglycans in BALB/c mice with progressive polyarthritis and ankylosing spondylitis induced by injection of human cartilage proteoglycan. Arthr. Rheum. 30, 306-318.
    • (1987) Arthr. Rheum. , vol.30 , pp. 306-318
    • Mikecz, K.1    Giant, T.T.2    Poole, A.R.3
  • 158
    • 0025166982 scopus 로고
    • Low levels of interleukin-4 and high levels of transforming growth factor β in rheumatoid synovitis
    • Miossec, P., Naviliat, M., D'Angeac, A. D., Sany, J., and Banchereau, J. (1990). Low levels of interleukin-4 and high levels of transforming growth factor β in rheumatoid synovitis. Arthr. Rheum. 33, 1180-1187.
    • (1990) Arthr. Rheum. , vol.33 , pp. 1180-1187
    • Miossec, P.1    Naviliat, M.2    D'Angeac, A.D.3    Sany, J.4    Banchereau, J.5
  • 161
    • 0027230553 scopus 로고
    • Thalidomide exerts its inhibitory action on tumor necrosis factor alpha by enhancing mRNA degradation
    • Moreira, A. L., Sampaio, E. P., Zmuidzinas, A., Frindt, P., Smith, K. A., and Kaplan, G. (1993). Thalidomide exerts its inhibitory action on tumor necrosis factor alpha by enhancing mRNA degradation. J. Exp. Med. 177, 1675-1680.
    • (1993) J. Exp. Med. , vol.177 , pp. 1675-1680
    • Moreira, A.L.1    Sampaio, E.P.2    Zmuidzinas, A.3    Frindt, P.4    Smith, K.A.5    Kaplan, G.6
  • 162
    • 0011352828 scopus 로고
    • Soluble tumor necrosis factor receptor (sTNFR): Results of a phase I dose-escalation study in patients with rheumatoid arthritis
    • Moreland, L. W., Margolies, G. R., Heck, L. W., Saway, P. A., Jacobs, C., Beck, C., Blosch, C., and Koopman, W. J. (1994). Soluble tumor necrosis factor receptor (sTNFR): Results of a phase I dose-escalation study in patients with rheumatoid arthritis. Arthr. Rheum. 37, S295.
    • (1994) Arthr. Rheum. , vol.37 , pp. S295
    • Moreland, L.W.1    Margolies, G.R.2    Heck, L.W.3    Saway, P.A.4    Jacobs, C.5    Beck, C.6    Blosch, C.7    Koopman, W.J.8
  • 164
    • 75949145891 scopus 로고
    • A new serum factor in patients with rheumatoid arthritis: The anti-perinuclear factor
    • Nienhuis, R. L. F., and Mandema, E. (1964). A new serum factor in patients with rheumatoid arthritis: The anti-perinuclear factor. Ann. Rheum. Dis. 23, 302-305.
    • (1964) Ann. Rheum. Dis. , vol.23 , pp. 302-305
    • Nienhuis, R.L.F.1    Mandema, E.2
  • 165
    • 0027739974 scopus 로고
    • Tumor necrosis factor-alpha induces cell type and tissue-specific expression of chemoattractant cytokines in vivo
    • Ohmori, V., Wyner, L., Narumi, S., Armstrong, D., Staler, M., and Hamilton, T. A. (1993). Tumor necrosis factor-alpha induces cell type and tissue-specific expression of chemoattractant cytokines in vivo. Am. J. Pathol. 142, 861-870.
    • (1993) Am. J. Pathol. , vol.142 , pp. 861-870
    • Ohmori, V.1    Wyner, L.2    Narumi, S.3    Armstrong, D.4    Staler, M.5    Hamilton, T.A.6
  • 166
  • 167
    • 0028088225 scopus 로고
    • Suppression of collagen-induced arthritis using an angiogenesis inhibitor, AGM-1470, and a microtubule stabilizer, taxol
    • Oliver, S. J., Banquerigo, M. L., and Brahn, E. (1994). Suppression of collagen-induced arthritis using an angiogenesis inhibitor, AGM-1470, and a microtubule stabilizer, taxol. Cell. Immunol. 157, 291-299.
    • (1994) Cell. Immunol. , vol.157 , pp. 291-299
    • Oliver, S.J.1    Banquerigo, M.L.2    Brahn, E.3
  • 168
    • 0028143149 scopus 로고
    • Functional activities of receptors for tumor necrosis factor-α on human vascular endothelial cells
    • Paleolog, E. M., Delasalle, S.-A. J., Buurman, W. A., and Feldmann, M. (1994). Functional activities of receptors for tumor necrosis factor-α on human vascular endothelial cells. Blood 84, 2578-2590.
    • (1994) Blood , vol.84 , pp. 2578-2590
    • Paleolog, E.M.1    Delasalle, S.-A.J.2    Buurman, W.A.3    Feldmann, M.4
  • 169
    • 0030013609 scopus 로고    scopus 로고
    • Monoclonal anti-tumour necrosis factor α deactivates vascular endothelium in rheumatoid arthritis
    • Paleolog, E. M., Hunt, M., Elliott, M. J., Woody, J. N., Feldmann, M., and Maini, R. N, (1996). Monoclonal anti-tumour necrosis factor α deactivates vascular endothelium in rheumatoid arthritis. Arthr. Rheum., 39, 1082-1091.
    • (1996) Arthr. Rheum. , vol.39 , pp. 1082-1091
    • Paleolog, E.M.1    Hunt, M.2    Elliott, M.J.3    Woody, J.N.4    Feldmann, M.5    Maini, R.N.6
  • 170
    • 0026752620 scopus 로고
    • The importance of the T cell in initiating and maintaining the chronic synovitis of rheumatoid arthritis
    • Panayi, G. S., Lanchbury, J. S., and Kingsley, G. H. (1992). The importance of the T cell in initiating and maintaining the chronic synovitis of rheumatoid arthritis. Arthr. Rheum. 35, 729.
    • (1992) Arthr. Rheum. , vol.35 , pp. 729
    • Panayi, G.S.1    Lanchbury, J.S.2    Kingsley, G.H.3
  • 171
    • 0018657510 scopus 로고
    • Mechanism of glucocorticosteroid action in immune processes
    • Panillo, J. E., and Fauci, A. S. (1979). Mechanism of glucocorticosteroid action in immune processes. Annu. Rev. Pharmacol. Toxicol. 19, 179-201.
    • (1979) Annu. Rev. Pharmacol. Toxicol. , vol.19 , pp. 179-201
    • Panillo, J.E.1    Fauci, A.S.2
  • 172
    • 0025266158 scopus 로고
    • Analysis of improvement in individual rheumatoid arthritis patients treated with disease-modifying antirheumatic drugs, based on the findings in patients treated with placebo
    • Paulus, H. E., Egger, M. J., Ward, J. R., Williams, H. J., and The Cooperative Systemic Studies of Rheumatic Diseases Group (1990). Analysis of improvement in individual rheumatoid arthritis patients treated with disease-modifying antirheumatic drugs, based on the findings in patients treated with placebo. Arthr. Rheum. 33, 477-484.
    • (1990) Arthr. Rheum. , vol.33 , pp. 477-484
    • Paulus, H.E.1    Egger, M.J.2    Ward, J.R.3    Williams, H.J.4
  • 173
    • 0026549481 scopus 로고
    • Angiogenesis inhibition suppresses collagen arthritis
    • Peacock, D. J., Banquerigo, M. L., and Brahn, E. (1992). Angiogenesis inhibition suppresses collagen arthritis. J. Exp. Med. 175, 1135-1138.
    • (1992) J. Exp. Med. , vol.175 , pp. 1135-1138
    • Peacock, D.J.1    Banquerigo, M.L.2    Brahn, E.3
  • 174
    • 0000609002 scopus 로고
    • Interleukin 1 induces leukocyte infiltration and cartilage proteoglycan degradation in the synovial joint
    • Pettipher, E. B., Higgs, G. A., and Henderson, B. (1986). Interleukin 1 induces leukocyte infiltration and cartilage proteoglycan degradation in the synovial joint. Proc. Natl. Acad. Sci. USA 83, 8749-8753.
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 8749-8753
    • Pettipher, E.B.1    Higgs, G.A.2    Henderson, B.3
  • 175
    • 0026787155 scopus 로고
    • Soluble forms of E-selectin, ICAM-1 and VCAM-1 are present in the supernatants of cytokine activated cultured endothelial cells
    • Pigott, R., Dillon, L. P., Hemingway, I. H., and Gearing, A. J. H. (1992). Soluble forms of E-selectin, ICAM-1 and VCAM-1 are present in the supernatants of cytokine activated cultured endothelial cells. Biochem. Biophys. Res. Commun. 187, 584-589.
    • (1992) Biochem. Biophys. Res. Commun. , vol.187 , pp. 584-589
    • Pigott, R.1    Dillon, L.P.2    Hemingway, I.H.3    Gearing, A.J.H.4
  • 176
    • 0026677361 scopus 로고
    • Evolution of collagen arthritis in mice is arrested by treatment with anti-tumour necrosis factor (TNF) antibody or a recombinant soluble TNF receptor
    • Piguet, P. F., Grau, G. E., Vesin, C, Loetscher, H., Gentz, R., and Lesslauer, W. (1992). Evolution of collagen arthritis in mice is arrested by treatment with anti-tumour necrosis factor (TNF) antibody or a recombinant soluble TNF receptor. Immunology 77,510-514.
    • (1992) Immunology , vol.77 , pp. 510-514
    • Piguet, P.F.1    Grau, G.E.2    Vesin, C.3    Loetscher, H.4    Gentz, R.5    Lesslauer, W.6
  • 178
    • 0027474185 scopus 로고
    • What is the natural history of rheumatoid arthritis?
    • Pincus, T., and Callahan, L. F. (1993). What is the natural history of rheumatoid arthritis? Rheum. Dis. Clin. North Am. 19, 123-151.
    • (1993) Rheum. Dis. Clin. North Am. , vol.19 , pp. 123-151
    • Pincus, T.1    Callahan, L.F.2
  • 179
    • 0027432324 scopus 로고
    • Up-regulation of vascular endothelial growth factor and its cognate receptors in a rat glioma model of tumor angiogenesis
    • Plate, K. H., Breier, G., Millauer, B., Ullrich, A., and Risau, W. (1993). Up-regulation of vascular endothelial growth factor and its cognate receptors in a rat glioma model of tumor angiogenesis. Cancer Res. 53, 5822-5827.
    • (1993) Cancer Res , vol.53 , pp. 5822-5827
    • Plate, K.H.1    Breier, G.2    Millauer, B.3    Ullrich, A.4    Risau, W.5
  • 180
    • 0026432216 scopus 로고
    • Inflammatory bowel disease
    • Podolsky, D. K. (1991). Inflammatory bowel disease. IV. Engl. J. Med. 325, 928-937.
    • (1991) IV. Engl. J. Med. , vol.325 , pp. 928-937
    • Podolsky, D.K.1
  • 181
    • 0025012838 scopus 로고
    • Tumor necrosis factor alpha functions in an autocrine manner in the induction of human immunodeficiency virus expression
    • Poli, G., Kinter, A., and Justenment, J. S. (1990). Tumor necrosis factor alpha functions in an autocrine manner in the induction of human immunodeficiency virus expression. Proc. Natl. Acad. Sci. USA 87, 782-785.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 782-785
    • Poli, G.1    Kinter, A.2    Justenment, J.S.3
  • 182
    • 0029045458 scopus 로고
    • The type 1 interleukin-1 receptor acts in series with tumor necrosis factor (TNF) to induce arthritis in TNF-transgenic mice
    • Probert, L., Plows, D., Kontogeorgos, G., and Kollias, G. (1995). The type 1 interleukin-1 receptor acts in series with tumor necrosis factor (TNF) to induce arthritis in TNF-transgenic mice. Eur. J. Immunol. 25, 1794-1797.
    • (1995) Eur. J. Immunol. , vol.25 , pp. 1794-1797
    • Probert, L.1    Plows, D.2    Kontogeorgos, G.3    Kollias, G.4
  • 183
    • 0023270053 scopus 로고
    • CD4 monoclonal antibody pairs for immunosuppression and tolerance induction
    • Qin, S. X., Cobbold, S. P., Tighe, H., Benjamin, R., and Waldmann, H. (1987). CD4 monoclonal antibody pairs for immunosuppression and tolerance induction. Eur. J. Immunol. 17, 1559-1165.
    • (1987) Eur. J. Immunol. , vol.17 , pp. 1559-11165
    • Qin, S.X.1    Cobbold, S.P.2    Tighe, H.3    Benjamin, R.4    Waldmann, H.5
  • 184
    • 0022361703 scopus 로고
    • Prevention of type II collagen-induced arthritis by in vivo treatment with anti-L3T4
    • Ranges, G. E., Sriram, S., and Cooper, S. M. (1985). Prevention of type II collagen-induced arthritis by in vivo treatment with anti-L3T4. J. Exp. Med. 162, 1105-1110.
    • (1985) J. Exp. Med. , vol.162 , pp. 1105-1110
    • Ranges, G.E.1    Sriram, S.2    Cooper, S.M.3
  • 185
    • 0029044028 scopus 로고
    • The therapeutic effects of an engineered human anti-tumour necrosis factor alpha antibody (CDP571) in rheumatoid arthritis
    • Rankin, E. C. C, Choy, E. H. S., Kassimos, D., Kingsley, G. H., Sopwith, A. M., Isenberg, D. A., and Panayi, G. S. (1995). The therapeutic effects of an engineered human anti-tumour necrosis factor alpha antibody (CDP571) in rheumatoid arthritis. Br. J. Rheumatol. 34, 334-342.
    • (1995) Br. J. Rheumatol. , vol.34 , pp. 334-342
    • Rankin, E.C.C.1    Choy, E.H.S.2    Kassimos, D.3    Kingsley, G.H.4    Sopwith, A.M.5    Isenberg, D.A.6    Panayi, G.S.7
  • 186
    • 0027503289 scopus 로고
    • Expression of die cytokine RANTES in human rheumatoid synovial fibroblasts. Differential regulation of RANTES and interleukin-8 genes by inflammatory cytokines
    • Rathanaswami, P., Hachicha, M., Sadick, M., Schall, T. J., and McColl, S. R. (1993). Expression of die cytokine RANTES in human rheumatoid synovial fibroblasts. Differential regulation of RANTES and interleukin-8 genes by inflammatory cytokines. J. Biol. Chem. 268, 5834-5839.
    • (1993) J. Biol. Chem. , vol.268 , pp. 5834-5839
    • Rathanaswami, P.1    Hachicha, M.2    Sadick, M.3    Schall, T.J.4    McColl, S.R.5
  • 187
    • 0024247501 scopus 로고
    • Tumor necrosis factor and HrV p24 antigen levels in serum of HIV-infected populations
    • Reddy, M. M., Sorrell, S. J., Lange, M., and Grieco, M. H. (1988). Tumor necrosis factor and HrV p24 antigen levels in serum of HIV-infected populations. J. Acquir. Immune Deficiency Syndrome 1, 436-440.
    • (1988) J. Acquir. Immune Deficiency Syndrome , vol.1 , pp. 436-440
    • Reddy, M.M.1    Sorrell, S.J.2    Lange, M.3    Grieco, M.H.4
  • 188
    • 0028227428 scopus 로고
    • Local anti-type II collagen antibody production in rheumatoid arthritis synovial fluid. Evidence for an HLA-DR4-restricted IgG response
    • Ronnelid, J., Lysholm, J., Engstrom-Laurent, A., Klareskog, L., and Heyman, B. (1994). Local anti-type II collagen antibody production in rheumatoid arthritis synovial fluid. Evidence for an HLA-DR4-restricted IgG response. Arthr. Rheum. 37, 1023-1029.
    • (1994) Arthr. Rheum. , vol.37 , pp. 1023-1029
    • Ronnelid, J.1    Lysholm, J.2    Engstrom-Laurent, A.3    Klareskog, L.4    Heyman, B.5
  • 189
    • 0023610252 scopus 로고
    • Tumor necrosis factor-alpha and hematopoietic progenitors: Effects of tumor necrosis factor on the growth of erythroid progenitors CFU-E and BFU-E and the hematopoietic cell lines k562, HL60, and HEL cells
    • Roodman, G. D., Bird, A., Hutzler, D., and Montgomery, W. (1987). Tumor necrosis factor-alpha and hematopoietic progenitors: Effects of tumor necrosis factor on the growth of erythroid progenitors CFU-E and BFU-E and the hematopoietic cell lines k562, HL60, and HEL cells. Exp. Hematol. 15, 928-935.
    • (1987) Exp. Hematol. , vol.15 , pp. 928-935
    • Roodman, G.D.1    Bird, A.2    Hutzler, D.3    Montgomery, W.4
  • 190
    • 0026608722 scopus 로고
    • Inhibitors of interleukin 1 activity in synovial fluids and in cultured synovial fluid mononuclear cells
    • Roux-Lombard, P., Modoux, C, Vischer, T., Grassi, J., and Dayer, J. M. (1992). Inhibitors of interleukin 1 activity in synovial fluids and in cultured synovial fluid mononuclear cells. J. Rheumatol. 19, 517-523.
    • (1992) J. Rheumatol. , vol.19 , pp. 517-523
    • Roux-Lombard, P.1    Modoux, C.2    Vischer, T.3    Grassi, J.4    Dayer, J.M.5
  • 192
    • 0001182063 scopus 로고
    • Inhibition of tumor necrosis factor (TNF) is effective alone or in combination with inhibition of interleukin-1 (IL-1) in reducing joint swelling in rodent bacterial cell wall-induced arthritis
    • Abstract
    • Russell, D., Tucker, K., Kohno, H., Thompson, R. C., and Schwab, J. (1994). Inhibition of tumor necrosis factor (TNF) is effective alone or in combination with inhibition of interleukin-1 (IL-1) in reducing joint swelling in rodent bacterial cell wall-induced arthritis. Arthr. Rheum. 37(Suppl.), S279. [Abstract]
    • (1994) Arthr. Rheum. , vol.37 , pp. S279
    • Russell, D.1    Tucker, K.2    Kohno, H.3    Thompson, R.C.4    Schwab, J.5
  • 194
    • 0022441214 scopus 로고
    • Tumour necrosis factor α stimulates resorption and inhibits synthesis of proteoglycan in cartilage
    • Saklatvala, J. (1986). Tumour necrosis factor α stimulates resorption and inhibits synthesis of proteoglycan in cartilage. Nature 322, 547-549.
    • (1986) Nature , vol.322 , pp. 547-549
    • Saklatvala, J.1
  • 195
    • 0022394427 scopus 로고
    • Pig interleukin-1. Purification of two immunologically different leukocyte proteins that cause cartilage resorption, lymphocyte activation and fever
    • Saklatvala, J., Sarsfield, S. J., and Townsend, Y. (1985). Pig interleukin-1. Purification of two immunologically different leukocyte proteins that cause cartilage resorption, lymphocyte activation and fever. J. Exp. Med. 162, 1208-1215.
    • (1985) J. Exp. Med. , vol.162 , pp. 1208-1215
    • Saklatvala, J.1    Sarsfield, S.J.2    Townsend, Y.3
  • 196
    • 0028289244 scopus 로고
    • Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha
    • Sallusto, F., and Lanzavecchia, A. (1994). Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha. J. Exp. Med. 179, 1109-1118.
    • (1994) J. Exp. Med. , vol.179 , pp. 1109-1118
    • Sallusto, F.1    Lanzavecchia, A.2
  • 197
    • 0009506682 scopus 로고
    • Tumor necrosis factor alpha (TNF) blockade enhances methotrexate (MTX) response in patients widi rheumatoid arthritis (RA)
    • Sander, O., Herborn, G., and Rau, R. (1995). Tumor necrosis factor alpha (TNF) blockade enhances methotrexate (MTX) response in patients widi rheumatoid arthritis (RA). Arthr. Rheum. 38, S266.
    • (1995) Arthr. Rheum. , vol.38 , pp. S266
    • Sander, O.1    Herborn, G.2    Rau, R.3
  • 199
    • 0023712236 scopus 로고
    • Detection of tumor necrosis factor α but not tumor necrosis factor β in rheumatoid arthritis synovial fluid and serum
    • Saxne, T., Palladino, M. A., Jr., Heinegard, D., Talal, N., and Wollheim, F. A. (1988). Detection of tumor necrosis factor α but not tumor necrosis factor β in rheumatoid arthritis synovial fluid and serum. Arthr. Rheum. 31, 1041-1045.
    • (1988) Arthr. Rheum. , vol.31 , pp. 1041-1045
    • Saxne, T.1    Palladino, M.A.2    Heinegard, D.3    Talal, N.4    Wollheim, F.A.5
  • 200
    • 0029004771 scopus 로고
    • Chimeric anti-TNF-α monoclonal antibody cA2 binds recombinant transmembrane TNF-α and activates immune effector functions
    • Scallon, B. J., Moore, M. A., Trinh, H., Knight, D. M., and Ghrayeb, J. (1995). Chimeric anti-TNF-α monoclonal antibody cA2 binds recombinant transmembrane TNF-α and activates immune effector functions. Cytokine 7, 251-259.
    • (1995) Cytokine , vol.7 , pp. 251-259
    • Scallon, B.J.1    Moore, M.A.2    Trinh, H.3    Knight, D.M.4    Ghrayeb, J.5
  • 202
    • 0002787839 scopus 로고
    • The endothelium in rheumatoid arthritis
    • J. H. Klippel and A. Dieppe, Eds.), Section 3,. Mosby, London
    • Schrieber, L. (1994). The endothelium in rheumatoid arthritis. In "Rheumatology" (J. H. Klippel and P. A. Dieppe, Eds.), Section 3, pp. 10.1-10.6. Mosby, London.
    • (1994) Rheumatology , pp. 101-106
    • Schrieber, L.1
  • 203
    • 0021999401 scopus 로고
    • Human anti-murine immunoglobulin responses in patients receiving monoclonal antibody therapy
    • Schroff, R. W., Foon, K. A., Beatty, S. M., Oldham, R. K., and Morgan, A., Jr. (1985). Human anti-murine immunoglobulin responses in patients receiving monoclonal antibody therapy. Cancer Res. 45, 879-885.
    • (1985) Cancer Res , vol.45 , pp. 879-885
    • Schroff, R.W.1    Foon, K.A.2    Beatty, S.M.3    Oldham, R.K.4    Morgan, A.5
  • 204
    • 0029017016 scopus 로고
    • The anti-perinuclear factor and the so-called anti-keratin antibodies are the same rheumatoid arthritis-specific autoantibodies
    • Sebbag, M., Simon, M., Vincent, C, Masson-Bessiere, C, Girbal, E., Jean-Jacques, D., and Serre, E. (1995). The anti-perinuclear factor and the so-called anti-keratin antibodies are the same rheumatoid arthritis-specific autoantibodies. J. Clin. Invest. 95, 2672-2679.
    • (1995) J. Clin. Invest. , vol.95 , pp. 2672-2679
    • Sebbag, M.1    Simon, M.2    Vincent, C.3    Masson-Bessiere, C.4    Girbal, E.5    Jean-Jacques, D.6    Serre, E.7
  • 205
    • 0027315234 scopus 로고
    • The specific type IV phosphodiesterase inhibitor rolipram suppresses tumor necrosis factor-α production by human mononuclear cells
    • Semmler, J., Wachtel, H., and Endres, S. (1993). The specific type IV phosphodiesterase inhibitor rolipram suppresses tumor necrosis factor-α production by human mononuclear cells. Int. J. Immunopharmacol. 15, 409-413.
    • (1993) Int. J. Immunopharmacol. , vol.15 , pp. 409-413
    • Semmler, J.1    Wachtel, H.2    Endres, S.3
  • 206
    • 0024362683 scopus 로고
    • Generation and characterization of hamster monoclonal antibodies that neutralize murine tumor necrosis factors
    • Sheehan, K., Ruddle, N. H., and Schreiber, R. D. (1989). Generation and characterization of hamster monoclonal antibodies that neutralize murine tumor necrosis factors.J. Immunol. 142, 3884-3893.
    • (1989) J. Immunol. , vol.142 , pp. 3884-3893
    • Sheehan, K.1    Ruddle, N.H.2    Schreiber, R.D.3
  • 207
    • 0028870050 scopus 로고
    • Induction of vascular endothelial growth factor expression by hypoxia and by glucose deficiency in multicell spheroids: Implications for tumor angiogenesis
    • Shweiki, D., Neeman, M., Itin, A., and Keshet, E. (1995). Induction of vascular endothelial growth factor expression by hypoxia and by glucose deficiency in multicell spheroids: Implications for tumor angiogenesis. Proc. Natl. Acad. Sci. USA 92, 768-772.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 768-772
    • Shweiki, D.1    Neeman, M.2    Itin, A.3    Keshet, E.4
  • 211
    • 0027964868 scopus 로고
    • Divergent T-cell cytokine patterns in inflammatory arthritis
    • Simon, A. K., Seipelt, E., and Sieper, J. (1994). Divergent T-cell cytokine patterns in inflammatory arthritis. Proc. Natl. Acad. Sci. USA 91, 8562-8566.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 8562-8566
    • Simon, A.K.1    Seipelt, E.2    Sieper, J.3
  • 212
    • 0016782192 scopus 로고
    • Rheumatoid arthritis in an urban South African Negro population
    • Soloman, L., Robin, G., and Valkenburg, H. A. (1975). Rheumatoid arthritis in an urban South African Negro population. Ann. Rheum. Dis. 34, 128-135.
    • (1975) Ann. Rheum. Dis. , vol.34 , pp. 128-135
    • Soloman, L.1    Robin, G.2    Valkenburg, H.A.3
  • 215
    • 0017878054 scopus 로고
    • Association of the B cell alloantigen DRW4 with rheumatoid arthritis
    • Stasny, P. (1978). Association of the B cell alloantigen DRW4 with rheumatoid arthritis. N Engl. J. Med. 298, 869-871.
    • (1978) N Engl. J. Med. , vol.298 , pp. 869-871
    • Stasny, P.1
  • 216
    • 0029896957 scopus 로고    scopus 로고
    • Reduction in cellularity and expression of adhesion molecules in rheumatoid synovial tissue after anti-TNFα monoclonal antibody treatment
    • Tak, P. P., Taylor, P. C., Breedveld, F. C., Smeets, T. J. M., Kluin, P. M., Meinders, A. E., and Maini, R. N. (1996). Reduction in cellularity and expression of adhesion molecules in rheumatoid synovial tissue after anti-TNFα monoclonal antibody treatment. Arthr. Rheum., 39, 1077-1081.
    • (1996) Arthr. Rheum. , vol.39 , pp. 1077-1081
    • Tak, P.P.1    Taylor, P.C.2    Breedveld, F.C.3    Smeets, T.J.M.4    Kluin, P.M.5    Meinders, A.E.6    Maini, R.N.7
  • 217
    • 0018955427 scopus 로고
    • The nucleotide sequence of human fibroblast interferon cDNA
    • Taniguchi, T., Ohno, S., Fujii-Kuriyama, Y., and Muramatsu, H. (1980). The nucleotide sequence of human fibroblast interferon cDNA. Gene 10, 11-15.
    • (1980) Gene , vol.10 , pp. 11-15
    • Taniguchi, T.1    Ohno, S.2    Fujii-Kuriyama, Y.3    Muramatsu, H.4
  • 219
    • 0026656850 scopus 로고
    • Involvement of endogenous tumour necrosis factor α and transforming growth factor β during induction of collagen type II arthritis in mice
    • Thorbecke, G. J., Shah, R., Leu, C. H., Kuruvilla, A. P., Hardison, A. M., and Palladino, M. A. (1992). Involvement of endogenous tumour necrosis factor α and transforming growth factor β during induction of collagen type II arthritis in mice. Proc. Natl. Acad. Sci. USA 89, 7375-7379.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 7375-7379
    • Thorbecke, G.J.1    Shah, R.2    Leu, C.H.3    Kuruvilla, A.P.4    Hardison, A.M.5    Palladino, M.A.6
  • 221
    • 0000429944 scopus 로고
    • Pharmacokinetics and metabolism of therapeutic and diagnostic antibodies
    • Plenum Press, New York
    • Trang, J. M. (1992). Pharmacokinetics and metabolism of therapeutic and diagnostic antibodies. In "Protein Pharmacokinetics and Metabolism," pp. 223-264. Plenum Press, New York.
    • (1992) Protein Pharmacokinetics and Metabolism , pp. 223-264
    • Trang, J.M.1
  • 223
    • 0029115051 scopus 로고
    • A randomized double-blind, placebo-controlled study of CD4 monoclonal antibody therapy in early rheumatoid arthritis
    • Van de Lubbe, P. A., Dijkmans, B. A. C., Markusse, H. M., Nassander, U., and Breedveld, F. C. (1995). A randomized double-blind, placebo-controlled study of CD4 monoclonal antibody therapy in early rheumatoid arthritis. Arthr. Rheum. 38, 1097-1106.
    • (1995) Arthr. Rheum. , vol.38 , pp. 1097-1106
    • van de Lubbe, P.A.1    Dijkmans, B.A.C.2    Markusse, H.M.3    Nassander, U.4    Breedveld, F.C.5
  • 224
    • 0008251156 scopus 로고
    • Uncoupling of inflammation and joint destruction in arthritis: Pivotal role of interleukin 1 in destruction
    • van den Berg, W. B. (1995). Uncoupling of inflammation and joint destruction in arthritis: Pivotal role of interleukin 1 in destruction. Rheumatol. Eur. 24(Suppl), 161-163.
    • (1995) Rheumatol. Eur. , vol.24 , pp. 161-163
    • van den Berg, W.B.1
  • 225
    • 0029192212 scopus 로고
    • Tumor necrosis factor in sepsis: Mediator of multiple organ failure or essential part ofhost defense? [editorial]
    • Review
    • van der Poll, T., and Lowry, S. F. (1995). Tumor necrosis factor in sepsis: Mediator of multiple organ failure or essential part ofhost defense? [editorial]. Shocks, 1-12. [Review]
    • (1995) Shocks , pp. 1-12
    • van der Poll, T.1    Lowry, S.F.2
  • 226
    • 0025647250 scopus 로고
    • Experimental endotoxemia in humans: Analysis of cytokine release and coagulation, fibrinolytic, and complement pathways
    • van Deventer, S. J., Buller, H. R., ten Cate, J. W., Aarden, L. A., Hack, C. E., and Sturk, A. (1990). Experimental endotoxemia in humans: Analysis of cytokine release and coagulation, fibrinolytic, and complement pathways. Blood 76, 2520-2526.
    • (1990) Blood , vol.76 , pp. 2520-2526
    • van Deventer, S.J.1    Buller, H.R.2    ten Cate, J.W.3    Aarden, L.A.4    Hack, C.E.5    Sturk, A.6
  • 230
    • 0026717674 scopus 로고
    • The pathophysiology of tumor necrosis factors
    • Vassalli, P. (1992). The pathophysiology of tumor necrosis factors. Annu. Rev. Immunol. 10, 411-452.
    • (1992) Annu. Rev. Immunol. , vol.10 , pp. 411-452
    • Vassalli, P.1
  • 232
    • 0023094408 scopus 로고
    • Association between tumour necrosis factor in serum and fatal outcome in patients with meningococcal disease
    • Waage, A., Halstensen, A., and Espevik, T. (1987). Association between tumour necrosis factor in serum and fatal outcome in patients with meningococcal disease. Lancet 1, 355-357.
    • (1987) Lancet , vol.1 , pp. 355-357
    • Waage, A.1    Halstensen, A.2    Espevik, T.3
  • 233
    • 0028152937 scopus 로고
    • Transforming growth factor β: The good, the bad, and the ugly
    • Wahl, S. M. (1994). Transforming growth factor β: The good, the bad, and the ugly. J. Exp. Med. 180, 1587-1590.
    • (1994) J. Exp. Med. , vol.180 , pp. 1587-1590
    • Wahl, S.M.1
  • 234
    • 0002238279 scopus 로고
    • Variations in the metabolism of immunoglobulins measured by turnover rates, in immunoglobulins
    • E. Merler, ed.),. National Academy of Sciences
    • Waldmann, T. A., Strober, W., and Blaese, R. M. (1970). Variations in the metabolism of immunoglobulins measured by turnover rates, in immunoglobulins. In "Biological Aspects & Clinical Uses" (E. Merler, ed.), pp. 33-51. National Academy of Sciences.
    • (1970) Biological Aspects & Clinical Uses , pp. 33-51
    • Waldmann, T.A.1    Strober, W.2    Blaese, R.M.3
  • 235
    • 0024353080 scopus 로고
    • Manipulation of T-cell responses with monoclonal antibodies
    • Waldmann, H. (1989). Manipulation of T-cell responses with monoclonal antibodies. Annu. Rev. Immunol. 7, 407-444.
    • (1989) Annu. Rev. Immunol. , vol.7 , pp. 407-444
    • Waldmann, H.1
  • 237
    • 0015546974 scopus 로고
    • Immunological unresponsiveness
    • Weigle, W. O. (1973). Immunological unresponsiveness. Adv. Immunol. 16, 61-122.
    • (1973) Adv. Immunol. , vol.16 , pp. 61-122
    • Weigle, W.O.1
  • 239
    • 0029026193 scopus 로고
    • Inherited and noninherited risk factors in rheumatoid arthritis
    • Weyand, C. M., and Goronzy, J. J. (1995). Inherited and noninherited risk factors in rheumatoid arthritis. Curr. Opin. Rheumatol. 7, 206-213.
    • (1995) Curr. Opin. Rheumatol. , vol.7 , pp. 206-213
    • Weyand, C.M.1    Goronzy, J.J.2
  • 240
    • 0026654604 scopus 로고
    • Homozygosity for the HLA-DRB1 allele selects for extra-articular manifestations in rheumatoid arthritis
    • Weyand, C. M., Xie, C, and Goronzy, J. J. (1992). Homozygosity for the HLA-DRB1 allele selects for extra-articular manifestations in rheumatoid arthritis. J. Clin. Invest. 89, 2033-2039.
    • (1992) J. Clin. Invest. , vol.89 , pp. 2033-2039
    • Weyand, C.M.1    Xie, C.2    Goronzy, J.J.3
  • 241
    • 0028907841 scopus 로고
    • Correlation between disease phenotype and genetic heterogeneity in rheumatoid arthritis
    • Weyand, C. M., McCarthy, T. G., and Goronzy, J. J. (1995). Correlation between disease phenotype and genetic heterogeneity in rheumatoid arthritis.J. Clin. Invest. 95, 2120-2126.
    • (1995) J. Clin. Invest. , vol.95 , pp. 2120-2126
    • Weyand, C.M.1    McCarthy, T.G.2    Goronzy, J.J.3
  • 242
    • 0027504109 scopus 로고
    • Tumor necrosis factor and the therapeutic potential of anti-tumor necrosis factor antibodies
    • Review
    • Wherry, J. C, Pennington, J. E., and Wenzel, R. P. (1993). Tumor necrosis factor and the therapeutic potential of anti-tumor necrosis factor antibodies. Crit. Care Med. 21, S436-S440. [Review]
    • (1993) Crit. Care Med. , vol.21 , pp. S436-S440
    • Wherry, J.C.1    Pennington, J.E.2    Wenzel, R.P.3
  • 243
    • 0029891449 scopus 로고    scopus 로고
    • Paradoxical effects of a synthetic metalloproteinase inhibitor which blocks bodi p55 and p75 TNF receptor shedding and TNFα processing in RA synovial membrane cell cultures
    • Williams, L., Gibbons, D. L., Gearing, A., Maini, R. N., Feldmann, M, and Brennan, F. M. (1996). Paradoxical effects of a synthetic metalloproteinase inhibitor which blocks bodi p55 and p75 TNF receptor shedding and TNFα processing in RA synovial membrane cell cultures. J. Clin. Invest. 97, 2833-2841.
    • (1996) J. Clin. Invest. , vol.97 , pp. 2833-2841
    • Williams, L.1    Gibbons, D.L.2    Gearing, A.3    Maini, R.N.4    Feldmann, M.5    Brennan, F.M.6
  • 245
    • 0026644298 scopus 로고
    • Anti-tumor necrosis factor ameliorates joint disease in murine collagen-induced arthritis
    • Williams, R. O., Feldmann, M, and Maini, R. N. (1992). Anti-tumor necrosis factor ameliorates joint disease in murine collagen-induced arthritis. Proc. Natl. Acad. Sci. USA 89, 9784-9788.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 9784-9788
    • Williams, R.O.1    Feldmann, M.2    Maini, R.N.3
  • 246
    • 0028226982 scopus 로고
    • Synergy between anti-CD4 and anti-TNF in the amelioration of established collagen-induced arthritis
    • Williams, R. O., Mason, L. J., Feldmann, M., and Maini, R. N. (1994). Synergy between anti-CD4 and anti-TNF in the amelioration of established collagen-induced arthritis. Proc. Natl. Acad. Sci. USA 91, 2762-2766.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 2762-2766
    • Williams, R.O.1    Mason, L.J.2    Feldmann, M.3    Maini, R.N.4
  • 247
    • 0028957027 scopus 로고
    • Successful therapy of collagen-induced arthritis with TNF receptor-IgG fusion protein and combination with anti-CD4
    • Williams, R. O., Ghrayeb, J., Feldmann, M., and Maini, R. N. (1995). Successful therapy of collagen-induced arthritis with TNF receptor-IgG fusion protein and combination with anti-CD4. Immunology 84, 433-439.
    • (1995) Immunology , vol.84 , pp. 433-439
    • Williams, R.O.1    Ghrayeb, J.2    Feldmann, M.3    Maini, R.N.4
  • 248
    • 0027534914 scopus 로고
    • Allelic polymorphism with the human TNFa promoter region is strongly associated with HLAAl, B8 and DR3 alleles
    • Wilson, A. G., De Vries, N., Pssian, F., van der Putte, L., and Duff, W. (1993). Allelic polymorphism with the human TNFa promoter region is strongly associated with HLAAl, B8 and DR3 alleles.J. Exp. Med. 177, 557-560.
    • (1993) J. Exp. Med. , vol.177 , pp. 557-560
    • Wilson, A.G.1    de Vries, N.2    Pssian, F.3    van der Putte, L.4    Duff, W.5
  • 250
    • 0027255950 scopus 로고
    • Humanized antibodies
    • Winter, G., and Harris, W. J. (1993). Humanized antibodies. Immunol. Today 14, 243-246.
    • (1993) Immunol. Today , vol.14 , pp. 243-246
    • Winter, G.1    Harris, W.J.2
  • 252
    • 0024417214 scopus 로고
    • Pristaneinduced arthritis. The immunologic and genetic features of an experimental murine model of autoimmune disease
    • Wooley, P. H., Seibold, J. R., Whalen, J. D., and Chapdelaine, J. M. (1989). Pristaneinduced arthritis. The immunologic and genetic features of an experimental murine model of autoimmune disease. Arthr. Rheum. 32, 1022-1030.
    • (1989) Arthr. Rheum. , vol.32 , pp. 1022-1030
    • Wooley, P.H.1    Seibold, J.R.2    Whalen, J.D.3    Chapdelaine, J.M.4
  • 253
    • 0027422060 scopus 로고
    • Influence of a recombinant human soluble tumor necrosis factor receptor FC fusion protein on type II collagen-induced arthritis in mice
    • Wooley, P. H., Dutcher, J., Widmer, M. B., and Gillis, S. (1993). Influence of a recombinant human soluble tumor necrosis factor receptor FC fusion protein on type II collagen-induced arthritis in mice. J. Immunol. 151, 6602-6607.
    • (1993) J. Immunol. , vol.151 , pp. 6602-6607
    • Wooley, P.H.1    Dutcher, J.2    Widmer, M.B.3    Gillis, S.4
  • 256
    • 0025744976 scopus 로고
    • Transforming growth factor beta stimulates the production of the tissue inhibitor of metalloproteinases (TIMP) by human synovial and skin fibroblasts
    • Wright, J. K., Cawston, T. E., and Hazleman, B. L. (1991). Transforming growth factor beta stimulates the production of the tissue inhibitor of metalloproteinases (TIMP) by human synovial and skin fibroblasts. Biochim. Biophys. Acta 1094, 207-210.
    • (1991) Biochim. Biophys. Acta , vol.1094 , pp. 207-210
    • Wright, J.K.1    Cawston, T.E.2    Hazleman, B.L.3


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