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Volumn 23, Issue 5 A, 2003, Pages 3855-3861

Inositol Hexaphosphate Inhibits Constitutive Activation of NF-κB in Androgen-independent Human Prostate Carcinoma DU145 Cells

Author keywords

Apoptosis; Inositol hexaphosphate; NF B; Prostate cancer

Indexed keywords

ANDROGEN; I KAPPA B ALPHA; I KAPPA B KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOCORTIN 5; PHYTIC ACID; PROTEIN P50; PROTEIN SUBUNIT; SYNAPTOTAGMIN;

EID: 0345305275     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (44)

References (42)
  • 2
    • 0030967371 scopus 로고    scopus 로고
    • Androgen deprivation as a strategy for prostate cancer chemoprevention
    • Aquilina JW, Lipsky JJ and Bostwick DG: Androgen deprivation as a strategy for prostate cancer chemoprevention. J Natl Cancer Inst 89: 689-696, 1997.
    • (1997) J Natl Cancer Inst , vol.89 , pp. 689-696
    • Aquilina, J.W.1    Lipsky, J.J.2    Bostwick, D.G.3
  • 3
    • 0032080609 scopus 로고
    • A flavonoid antioxidant, silymarin, inhibits activation of erbB1 signaling and induces cyclin-dependent kinase inhibitors, G1 arrest, and anticarcinogenic effects in human prostate carcinoma DU145 cells
    • Zi X, Grasso AW, Kung HJ and Agarwal R: A flavonoid antioxidant, silymarin, inhibits activation of erbB1 signaling and induces cyclin-dependent kinase inhibitors, G1 arrest, and anticarcinogenic effects in human prostate carcinoma DU145 cells. Cancer Res 58: 1920-1929, 1988.
    • (1988) Cancer Res , vol.58 , pp. 1920-1929
    • Zi, X.1    Grasso, A.W.2    Kung, H.J.3    Agarwal, R.4
  • 4
    • 0034668148 scopus 로고    scopus 로고
    • Cell signaling and regulators of cell cycle as molecular targets for prostate cancer prevention by dietary agents
    • Agarwal R: Cell signaling and regulators of cell cycle as molecular targets for prostate cancer prevention by dietary agents. Biochem Pharmacol 60: 1051-1059, 2000.
    • (2000) Biochem Pharmacol , vol.60 , pp. 1051-1059
    • Agarwal, R.1
  • 5
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D and Weinberg RA: The hallmarks of cancer. Cell 100: 57-70, 2000.
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 6
    • 0032894222 scopus 로고    scopus 로고
    • Epidermal growth factor (EGF) receptor blockade inhibits the action of EGF, insulin-like growth factor I, and a protein kinase A activator on the mitogen-activated protein kinase pathway in prostate cancer cell lines
    • Putz T, Culig Z, Eder IE, Nessler-Menardi C, Bartsch G, Grunicke H, Uberall F and Klocker H: Epidermal growth factor (EGF) receptor blockade inhibits the action of EGF, insulin-like growth factor I, and a protein kinase A activator on the mitogen-activated protein kinase pathway in prostate cancer cell lines. Cancer Res 59: 227-233, 1999.
    • (1999) Cancer Res , vol.59 , pp. 227-233
    • Putz, T.1    Culig, Z.2    Eder, I.E.3    Nessler-Menardi, C.4    Bartsch, G.5    Grunicke, H.6    Uberall, F.7    Klocker, H.8
  • 7
    • 0033119571 scopus 로고    scopus 로고
    • Antiapoptotic signaling in LNCaP prostate cancer cells: A survival signaling pathway independent of phosphatidylinositol 3′-kinase and Akt/protein kinase B
    • Carson JP, Kulik G and Weber MJ: Antiapoptotic signaling in LNCaP prostate cancer cells: a survival signaling pathway independent of phosphatidylinositol 3′-kinase and Akt/protein kinase B. Cancer Res 59: 1449-1453, 1999.
    • (1999) Cancer Res , vol.59 , pp. 1449-1453
    • Carson, J.P.1    Kulik, G.2    Weber, M.J.3
  • 8
    • 0033564514 scopus 로고    scopus 로고
    • The phosphatidylinositol 3′-kinase pathway is a dominant growth factor-activated cell survival pathway in LNCaP human prostate carcinoma cells
    • Lin J, Adam RM, Santiestevan E and Freeman MR: The phosphatidylinositol 3′-kinase pathway is a dominant growth factor-activated cell survival pathway in LNCaP human prostate carcinoma cells. Cancer Res 59: 2891-2897, 1999.
    • (1999) Cancer Res , vol.59 , pp. 2891-2897
    • Lin, J.1    Adam, R.M.2    Santiestevan, E.3    Freeman, M.R.4
  • 9
    • 0033555967 scopus 로고    scopus 로고
    • Activation of mitogen-activated protein kinase associated with prostate cancer progression
    • Gioeli D, Mandell JW, Petroni GR, Frierson Jr HF and Weber MJ: Activation of mitogen-activated protein kinase associated with prostate cancer progression. Cancer Res 59: 279-284, 1999.
    • (1999) Cancer Res , vol.59 , pp. 279-284
    • Gioeli, D.1    Mandell, J.W.2    Petroni, G.R.3    Frierson Jr., H.F.4    Weber, M.J.5
  • 10
    • 0033517999 scopus 로고    scopus 로고
    • Constitutive activation of IkappaB kinase alpha and NF-kappaB in prostate cancer cells is inhibited by ibuprofen
    • Palayoor ST, Youmell MY, Calderwood SK, Coleman CN and Price BD: Constitutive activation of IkappaB kinase alpha and NF-kappaB in prostate cancer cells is inhibited by ibuprofen. Oncogene 18: 7389-7394, 1999.
    • (1999) Oncogene , vol.18 , pp. 7389-7394
    • Palayoor, S.T.1    Youmell, M.Y.2    Calderwood, S.K.3    Coleman, C.N.4    Price, B.D.5
  • 11
    • 0028834881 scopus 로고
    • Rel/NF-kappa B/I kappa B story
    • Miyamoto S and Verma IM: Rel/NF-kappa B/I kappa B story. Adv Cancer Res 66: 255-292, 1995.
    • (1995) Adv Cancer Res , vol.66 , pp. 255-292
    • Miyamoto, S.1    Verma, I.M.2
  • 12
    • 0030271387 scopus 로고    scopus 로고
    • NF-kappa B: Ten years after
    • Baeuerle PA and Baltimore D: NF-kappa B: ten years after. Cell 87: 13-20, 1996.
    • (1996) Cell , vol.87 , pp. 13-20
    • Baeuerle, P.A.1    Baltimore, D.2
  • 14
    • 0032575379 scopus 로고    scopus 로고
    • Direct phosphorylation of IkappaB by IKKalpha and IKKbeta: Discrimination between free and NF-kappaB-bound substrate
    • Zandi E, Chen Y and Karin M: Direct phosphorylation of IkappaB by IKKalpha and IKKbeta: discrimination between free and NF-kappaB-bound substrate. Science 281: 1360-1363, 1998.
    • (1998) Science , vol.281 , pp. 1360-1363
    • Zandi, E.1    Chen, Y.2    Karin, M.3
  • 15
    • 0028978032 scopus 로고
    • Phosphorylation of human I kappa B-alpha on serines 32 and 36 controls I kappa B-alpha proteolysis and NF-kappa B activation in response to diverse stimuli
    • Traenckner EB, Pahl HL, Henkel T, Schmidt KN, Wilk S and Baeuerle PA: Phosphorylation of human I kappa B-alpha on serines 32 and 36 controls I kappa B-alpha proteolysis and NF-kappa B activation in response to diverse stimuli. EMBO J 14: 2876-2883, 1995.
    • (1995) EMBO J , vol.14 , pp. 2876-2883
    • Traenckner, E.B.1    Pahl, H.L.2    Henkel, T.3    Schmidt, K.N.4    Wilk, S.5    Baeuerle, P.A.6
  • 16
    • 0032508414 scopus 로고    scopus 로고
    • NF-κB antiapoptosis: Induction of TRAF1, TRAF2, c-IAP1 and c-IAP2 to suppress caspase-8-activation
    • Wang CY, Mayo MW, Korneluk RG, Goeddel DV and Baldwin AS Jr: NF-κB antiapoptosis: induction of TRAF1, TRAF2, c-IAP1 and c-IAP2 to suppress caspase-8-activation. Science 281: 1680-1683, 1998.
    • (1998) Science , vol.281 , pp. 1680-1683
    • Wang, C.Y.1    Mayo, M.W.2    Korneluk, R.G.3    Goeddel, D.V.4    Baldwin Jr., A.S.5
  • 17
    • 0032516651 scopus 로고    scopus 로고
    • IEX-1L, an apoptosis inhibitor involved in NF-kappaB-mediated cell survival
    • Wu MX, Ao Z, Prasad KV, Wu R and Schlossman SF: IEX-1L, an apoptosis inhibitor involved in NF-kappaB-mediated cell survival. Science 281: 998-1001, 1998.
    • (1998) Science , vol.281 , pp. 998-1001
    • Wu, M.X.1    Ao, Z.2    Prasad, K.V.3    Wu, R.4    Schlossman, S.F.5
  • 18
    • 0030903321 scopus 로고    scopus 로고
    • Protective effects of silymarin against photocarcinogenesis in a mouse skin model
    • Katiyar SK, Korman NJ, Mukhtar H and Agarwal R: Protective effects of silymarin against photocarcinogenesis in a mouse skin model. J Natl Cancer Inst 89: 556-566, 1997.
    • (1997) J Natl Cancer Inst , vol.89 , pp. 556-566
    • Katiyar, S.K.1    Korman, N.J.2    Mukhtar, H.3    Agarwal, R.4
  • 19
    • 0032821619 scopus 로고    scopus 로고
    • Anti-tumor-promoting activity of a polyphenolic fraction isolated from grape seeds in the mouse skin two-stage initiation-promotion protocol and identification of procyanidin B5-3′-gallate as the most effective antioxidant constituent
    • Zhao J, Wang J, Chen Y and Agarwal R: Anti-tumor-promoting activity of a polyphenolic fraction isolated from grape seeds in the mouse skin two-stage initiation-promotion protocol and identification of procyanidin B5-3′-gallate as the most effective antioxidant constituent. Carcinogenesis 20: 1737-1745, 1999.
    • (1999) Carcinogenesis , vol.20 , pp. 1737-1745
    • Zhao, J.1    Wang, J.2    Chen, Y.3    Agarwal, R.4
  • 20
    • 0033509354 scopus 로고    scopus 로고
    • Genistein inhibits NF-kappa B activation in prostate cancer cells
    • Davis JN, Kucuk O and Sarkar FH: Genistein inhibits NF-kappa B activation in prostate cancer cells. Nutr Cancer 35: 167-174, 1999.
    • (1999) Nutr Cancer , vol.35 , pp. 167-174
    • Davis, J.N.1    Kucuk, O.2    Sarkar, F.H.3
  • 21
    • 0028867742 scopus 로고
    • Activation of transcription factor NF-kappa B is suppressed by curcumin (diferuloylmethane)
    • Singh S and Aggarwal BB: Activation of transcription factor NF-kappa B is suppressed by curcumin (diferuloylmethane) [corrected]. J Biol Chem 270: 24995-25000, 1995.
    • (1995) J Biol Chem , vol.270 , pp. 24995-25000
    • Singh, S.1    Aggarwal, B.B.2
  • 22
    • 0035992417 scopus 로고    scopus 로고
    • Inhibition of nuclear factor kappaB activation in PC3 cells by genistein is mediated via Akt signaling pathway
    • Li Y and Sarkar FH: Inhibition of nuclear factor kappaB activation in PC3 cells by genistein is mediated via Akt signaling pathway. Clin Cancer Res 8: 2369-2377, 2002.
    • (2002) Clin Cancer Res , vol.8 , pp. 2369-2377
    • Li, Y.1    Sarkar, F.H.2
  • 23
    • 0036733776 scopus 로고    scopus 로고
    • Suppression of 7,12-dimethylbenz(a) anthracene-induced mammary carcinogenesis in rats by resveratrol: Role of nuclear factor-kappaB, cyclooxygenase 2, and matrix metalloprotease 9
    • Banerjee S, Bueso-Ramos C and Aggarwal BB: Suppression of 7,12-dimethylbenz(a) anthracene-induced mammary carcinogenesis in rats by resveratrol: role of nuclear factor-kappaB, cyclooxygenase 2, and matrix metalloprotease 9. Cancer Res 62: 4945-4954, 2002.
    • (2002) Cancer Res , vol.62 , pp. 4945-4954
    • Banerjee, S.1    Bueso-Ramos, C.2    Aggarwal, B.B.3
  • 24
    • 0037034863 scopus 로고    scopus 로고
    • Silibinin inhibits constitutive and TNFalpha-induced activation of NF-kappaB and sensitizes human prostate carcinoma DU145 cells to TNFalpha-induced apoptosis
    • Dhanalakshmi S, Singh RP, Agarwal C and Agarwal R: Silibinin inhibits constitutive and TNFalpha-induced activation of NF-kappaB and sensitizes human prostate carcinoma DU145 cells to TNFalpha-induced apoptosis. Oncogene 21: 1759-1767, 2002.
    • (2002) Oncogene , vol.21 , pp. 1759-1767
    • Dhanalakshmi, S.1    Singh, R.P.2    Agarwal, C.3    Agarwal, R.4
  • 25
    • 0023936256 scopus 로고
    • Suppression of large intestinal cancer in F344 rats by inositol hexaphosphate
    • Shamsuddin AM, Elsayed AM and Ullah A: Suppression of large intestinal cancer in F344 rats by inositol hexaphosphate. Carcinogenesis 9: 577-580, 1988.
    • (1988) Carcinogenesis , vol.9 , pp. 577-580
    • Shamsuddin, A.M.1    Elsayed, A.M.2    Ullah, A.3
  • 26
    • 0032787156 scopus 로고    scopus 로고
    • Mammary tumor inhibition by IP6: A review
    • Shamsuddin AM and Vucenik I: Mammary tumor inhibition by IP6: a review. Anticancer Res 19: 3671-3674, 1999.
    • (1999) Anticancer Res , vol.19 , pp. 3671-3674
    • Shamsuddin, A.M.1    Vucenik, I.2
  • 27
    • 0032217236 scopus 로고    scopus 로고
    • IP6 treatment of liver cancer. I: IP6 inhibits growth reverses transformed phenotype in HepG2 human liver cancer cell line
    • Vucenik I, Tantivejkul K, Zhang JS, Cole KE, Saied I and Shamsuddin AM: IP6 treatment of liver cancer. I: IP6 inhibits growth reverses transformed phenotype in HepG2 human liver cancer cell line. Anticancer Res 18: 4083-4090, 1998.
    • (1998) Anticancer Res , vol.18 , pp. 4083-4090
    • Vucenik, I.1    Tantivejkul, K.2    Zhang, J.S.3    Cole, K.E.4    Saied, I.5    Shamsuddin, A.M.6
  • 28
    • 0032787043 scopus 로고    scopus 로고
    • Chemoprevention of pulmonary carcinogenesis by myo-inositol
    • Wattenberg LW: Chemoprevention of pulmonary carcinogenesis by myo-inositol. Anticancer Res 19: 3659-3661, 1999.
    • (1999) Anticancer Res , vol.19 , pp. 3659-3661
    • Wattenberg, L.W.1
  • 29
    • 0032785869 scopus 로고    scopus 로고
    • Inhibition of skin cancer by IP6 in vivo: Initiation-promotion model
    • Ishikawa T, Nakatsuru Y, Zarkovic M and Shamsuddin AM: Inhibition of skin cancer by IP6 in vivo: initiation-promotion model. Anticancer Res 19: 3749-3752, 1999.
    • (1999) Anticancer Res , vol.19 , pp. 3749-3752
    • Ishikawa, T.1    Nakatsuru, Y.2    Zarkovic, M.3    Shamsuddin, A.M.4
  • 30
    • 0026658125 scopus 로고
    • Antitumor activity of phytic acid (inositol hexaphosphate) in murine transplanted and metastatic fibrosarcoma, pilot study
    • Vucenik I, Tomazik VJ, Fabian D and Shamsuddin AM: Antitumor activity of phytic acid (inositol hexaphosphate) in murine transplanted and metastatic fibrosarcoma, pilot study. Cancer Lett 65: 9-13, 1992.
    • (1992) Cancer Lett , vol.65 , pp. 9-13
    • Vucenik, I.1    Tomazik, V.J.2    Fabian, D.3    Shamsuddin, A.M.4
  • 31
    • 0034526276 scopus 로고    scopus 로고
    • Impairment of erbB1 receptor and fluid phase endocytosis and associated mitogenic signaling by inositol hexaphosphate in human prostate carcinoma DU145 cells
    • Zi X Singh RP and Agarwal R: Impairment of erbB1 receptor and fluid phase endocytosis and associated mitogenic signaling by inositol hexaphosphate in human prostate carcinoma DU145 cells. Carcinogenesis 21: 2225-2235, 2000.
    • (2000) Carcinogenesis , vol.21 , pp. 2225-2235
    • Zi, X.1    Singh, R.P.2    Agarwal, R.3
  • 32
    • 0030793370 scopus 로고    scopus 로고
    • Inositol hexaphosphate inhibits cell transformation and activator protein 1 activation by targeting phosphatidylinositol-3 kinase
    • Huang C, Ma WI, Hecht SS and Dong Z: Inositol hexaphosphate inhibits cell transformation and activator protein 1 activation by targeting phosphatidylinositol-3 kinase. Cancer Res 57: 2873-2878, 1997.
    • (1997) Cancer Res , vol.57 , pp. 2873-2878
    • Huang, C.1    Ma, W.I.2    Hecht, S.S.3    Dong, Z.4
  • 33
    • 0029122135 scopus 로고
    • Inositol hexaphosphate inhibits growth and induces differentiation of PC-3 human prostate cancer cells
    • Shamsuddin AM and Yang GY: Inositol hexaphosphate inhibits growth and induces differentiation of PC-3 human prostate cancer cells. Carcinogenesis 16: 1975-1979, 1995.
    • (1995) Carcinogenesis , vol.16 , pp. 1975-1979
    • Shamsuddin, A.M.1    Yang, G.Y.2
  • 34
    • 0032763994 scopus 로고    scopus 로고
    • Metabolism and cellular functions of IP6: A review
    • Shamsuddin AM: Metabolism and cellular functions of IP6: a review. Anticancer Res 19: 3733-3736, 1999.
    • (1999) Anticancer Res , vol.19 , pp. 3733-3736
    • Shamsuddin, A.M.1
  • 35
    • 0034746736 scopus 로고    scopus 로고
    • G0/G1 arrest and S phase inhibition of human cancer cell lines by inositol hexaphosphate (IP6)
    • El-Sherbiny YM, Cox MC, Ismail ZA, Shamsuddin AM and Vucenik I: G0/G1 arrest and S phase inhibition of human cancer cell lines by inositol hexaphosphate (IP6). Anticancer Res 21: 2393-2403, 2001.
    • (2001) Anticancer Res , vol.21 , pp. 2393-2403
    • El-Sherbiny, Y.M.1    Cox, M.C.2    Ismail, Z.A.3    Shamsuddin, A.M.4    Vucenik, I.5
  • 36
    • 0036546501 scopus 로고    scopus 로고
    • NF-kappaB in cancer: From innocent bystander to major culprit
    • Karin M, Cao Y, Greten FR and Li ZW: NF-kappaB in cancer: from innocent bystander to major culprit. Nat Rev Cancer 2: 301-310, 2002.
    • (2002) Nat Rev Cancer , vol.2 , pp. 301-310
    • Karin, M.1    Cao, Y.2    Greten, F.R.3    Li, Z.W.4
  • 37
    • 0036898130 scopus 로고    scopus 로고
    • Gene expression profiles of genistein-treated PC3 prostate cancer cells
    • Li Y and Sarkar FH: Gene expression profiles of genistein-treated PC3 prostate cancer cells. J Nutr 132: 3623-3631, 2002.
    • (2002) J Nutr , vol.132 , pp. 3623-3631
    • Li, Y.1    Sarkar, F.H.2
  • 38
    • 0035849720 scopus 로고    scopus 로고
    • Blockade of NF-kappa B activity in human prostate cancer cells is associated with suppression of angiogenesis, invasion, and metastasis
    • Huang S, Pettaway CA, Uehara H, Bucana CD and Fidler IJ: Blockade of NF-kappa B activity in human prostate cancer cells is associated with suppression of angiogenesis, invasion, and metastasis. Oncogene 20: 4188-4197, 2001.
    • (2001) Oncogene , vol.20 , pp. 4188-4197
    • Huang, S.1    Pettaway, C.A.2    Uehara, H.3    Bucana, C.D.4    Fidler, I.J.5
  • 40
    • 0029858387 scopus 로고    scopus 로고
    • TNF-and cancer therapy-induced apoptosis: Potentiation by inhibition of NF-κB
    • Wang CY, Mayo MW and Baldwin AS Jr: TNF-and cancer therapy-induced apoptosis: potentiation by inhibition of NF-κB. Science 274: 784-787, 1996.
    • (1996) Science , vol.274 , pp. 784-787
    • Wang, C.Y.1    Mayo, M.W.2    Baldwin Jr., A.S.3
  • 41
    • 0032905030 scopus 로고    scopus 로고
    • Control of inducible chemoresistance: Enhanced anti-tumor therapy through increased apoptosis by inhibition of NF-κB
    • Wang CY, Cusack JC Jr, Liu R and Baldwin AS Jr: Control of inducible chemoresistance: Enhanced anti-tumor therapy through increased apoptosis by inhibition of NF-κB. Nat Med 5: 412-417, 1999.
    • (1999) Nat Med , vol.5 , pp. 412-417
    • Wang, C.Y.1    Cusack Jr., J.C.2    Liu, R.3    Baldwin Jr., A.S.4
  • 42
    • 0036009115 scopus 로고    scopus 로고
    • NF-kappaB at the crossroads of life and death
    • Karin M and Lin A: NF-kappaB at the crossroads of life and death. Nature Imunol 3: 221-227, 2002.
    • (2002) Nature Imunol , vol.3 , pp. 221-227
    • Karin, M.1    Lin, A.2


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