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Volumn 57, Issue 14, 1997, Pages 2873-2878

Inositol hexaphosphate inhibits cell transformation and activator protein 1 activation by targeting phosphatidylinositol-3' kinase

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; INOSITOL PHOSPHATE; PHOSPHATIDYLINOSITOL 3 KINASE; PHYTIC ACID;

EID: 0030793370     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (111)

References (52)
  • 1
    • 0026786433 scopus 로고
    • Photoaffimity labeling and characterization of isolated inositol 1,3,4,5-tetrakisphosphate- and inositol hexakisphosphate-binding proteins
    • Theibert, A. B., Estevez, V. A., Mourey, R. J., Marecek, J. F., Barrow, R. K., Prestwich, G. D., and Snyder, S. H. Photoaffimity labeling and characterization of isolated inositol 1,3,4,5-tetrakisphosphate- and inositol hexakisphosphate-binding proteins. J. Biol. Chem., 267: 9071-9079, 1992.
    • (1992) J. Biol. Chem. , vol.267 , pp. 9071-9079
    • Theibert, A.B.1    Estevez, V.A.2    Mourey, R.J.3    Marecek, J.F.4    Barrow, R.K.5    Prestwich, G.D.6    Snyder, S.H.7
  • 3
    • 0027389279 scopus 로고
    • Comparison of the levels of inositol metabolites in transformed haemopoietic cells and their normal counterparts
    • Bunce, C. M., French, P. J., Allen, P., Mountford, J. C., Moor, B., Greaves, M. F., Michell, R. H., and Brown, G. Comparison of the levels of inositol metabolites in transformed haemopoietic cells and their normal counterparts. Biochem. J., 289: 667-673, 1993.
    • (1993) Biochem. J. , vol.289 , pp. 667-673
    • Bunce, C.M.1    French, P.J.2    Allen, P.3    Mountford, J.C.4    Moor, B.5    Greaves, M.F.6    Michell, R.H.7    Brown, G.8
  • 5
    • 0025021262 scopus 로고
    • Antioxidant functions of phytic acid
    • Graf, E., and Eaton, J. W. Antioxidant functions of phytic acid. Free Radical Biol. Med., 8: 61-69, 1990.
    • (1990) Free Radical Biol. Med. , vol.8 , pp. 61-69
    • Graf, E.1    Eaton, J.W.2
  • 6
    • 0023481251 scopus 로고
    • Occurrence and extracellular actions of inositol penlakis- and hexakisphosphate in mammalian brain
    • Vallejo, M., Jackson, T. R., Lightman, S., and Hanley, M. R. Occurrence and extracellular actions of inositol penlakis- and hexakisphosphate in mammalian brain. Nature (Lond.), 330: 656-658, 1987.
    • (1987) Nature (Lond.) , vol.330 , pp. 656-658
    • Vallejo, M.1    Jackson, T.R.2    Lightman, S.3    Hanley, M.R.4
  • 7
    • 0026561419 scopus 로고
    • Specific binding of inositol hexakisphosphate (phytic acid) to adrenal chromaffin cell membrane and effects on calcium-dependent catecholamine release
    • Regunathan, S., Reis, D. J., and Wahlestedt, C. Specific binding of inositol hexakisphosphate (phytic acid) to adrenal chromaffin cell membrane and effects on calcium-dependent catecholamine release. Biochem. Pharmacol., 43: 1331-1336, 1992.
    • (1992) Biochem. Pharmacol. , vol.43 , pp. 1331-1336
    • Regunathan, S.1    Reis, D.J.2    Wahlestedt, C.3
  • 10
    • 0026318612 scopus 로고
    • Inositol 1,3,4,5-tetrakisphosphate and inositol hexakisphosphate receptor proteins: Isolation and characterization from rat brain
    • Theibert, A. B., Estevez, V. A., Ferris, C. D., Danoff, S. K., Barrow, R. K., Prestwich, G. D., and Snyder, S. H. Inositol 1,3,4,5-tetrakisphosphate and inositol hexakisphosphate receptor proteins: isolation and characterization from rat brain. Proc. Natl. Acad. Sci. USA, 88: 3165-3169, 1991.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 3165-3169
    • Theibert, A.B.1    Estevez, V.A.2    Ferris, C.D.3    Danoff, S.K.4    Barrow, R.K.5    Prestwich, G.D.6    Snyder, S.H.7
  • 11
    • 0026705855 scopus 로고
    • Structural and functional characterization of an inositol polyphosphate receptor from cerebellum
    • Chadwick, C. C., Timerman, A. P., Saito, A., Mayreitner, M., Shindler, H., and Fleischer, S. Structural and functional characterization of an inositol polyphosphate receptor from cerebellum. J. Biol. Chem., 267: 3473-3481, 1992.
    • (1992) J. Biol. Chem. , vol.267 , pp. 3473-3481
    • Chadwick, C.C.1    Timerman, A.P.2    Saito, A.3    Mayreitner, M.4    Shindler, H.5    Fleischer, S.6
  • 13
    • 0023664866 scopus 로고
    • Phytic acid, a natural antioxidant
    • Graf, E., and Empson, K. L. Phytic acid, a natural antioxidant. J. Biol. Chem., 262: 11647-11650, 1987.
    • (1987) J. Biol. Chem. , vol.262 , pp. 11647-11650
    • Graf, E.1    Empson, K.L.2
  • 14
    • 0023481251 scopus 로고
    • Occurrence and extracellular actions of inositol pentakis- and hexakisphosphate in mammalian brain
    • Vallejo, M., Jackson, T., Lightman, S., and Hanley, M. R. Occurrence and extracellular actions of inositol pentakis- and hexakisphosphate in mammalian brain. Nature (Lond.), 330: 656-658, 1987.
    • (1987) Nature (Lond.) , vol.330 , pp. 656-658
    • Vallejo, M.1    Jackson, T.2    Lightman, S.3    Hanley, M.R.4
  • 15
    • 0029122135 scopus 로고
    • Inositol hexaphosphate inhibits growth and induces differentiation of PC-3 human prostate cancer cells
    • Lond.
    • Shamsuddin, A. M., and Yang, G-Y. Inositol hexaphosphate inhibits growth and induces differentiation of PC-3 human prostate cancer cells. Carcinogenesis (Lond.), 16: 1975-1979, 1995.
    • (1995) Carcinogenesis , vol.16 , pp. 1975-1979
    • Shamsuddin, A.M.1    Yang, G.-Y.2
  • 17
    • 0023936256 scopus 로고
    • Suppression of large intestinal cancer in F-344 rats by inositol hexaphosphate
    • Lond.
    • Shamsuddin, A. M., Elsayed, A. M., and Ullah, A. Suppression of large intestinal cancer in F-344 rats by inositol hexaphosphate. Carcinogenesis (Lond.), 9: 577-580, 1988.
    • (1988) Carcinogenesis , vol.9 , pp. 577-580
    • Shamsuddin, A.M.1    Elsayed, A.M.2    Ullah, A.3
  • 18
    • 0026780284 scopus 로고
    • Effects of inositol hexaphosphate on growth and differentiation in K-562 erythroleukemia cell line
    • Shamsuddin, A. M., Baten, A., and Lalwani, N. D. Effects of inositol hexaphosphate on growth and differentiation in K-562 erythroleukemia cell line. Cancer Lett., 64: 195-202, 1992.
    • (1992) Cancer Lett. , vol.64 , pp. 195-202
    • Shamsuddin, A.M.1    Baten, A.2    Lalwani, N.D.3
  • 19
    • 0027442548 scopus 로고
    • Growth inhibition and differentiation of HT-29 cell in vitro by inositol hexaphosphate (phytic acid)
    • Lond.
    • Sakamoto, K., Venkatraman, G., and Shamsuddin, A. M. Growth inhibition and differentiation of HT-29 cell in vitro by inositol hexaphosphate (phytic acid). Carcinogenesis (Lond.), 14: 1815-1819, 1993.
    • (1993) Carcinogenesis , vol.14 , pp. 1815-1819
    • Sakamoto, K.1    Venkatraman, G.2    Shamsuddin, A.M.3
  • 20
    • 0027761183 scopus 로고
    • Inhibition of rat mammary carcinogenesis by inositol hexaphosphate (phytic acid). A pilot study
    • Vucenik, I., Sakamoto, K., Bansal, M., and Shamsuddin, A. M. Inhibition of rat mammary carcinogenesis by inositol hexaphosphate (phytic acid). A pilot study. Cancer Lett., 75: 95-102, 1993.
    • (1993) Cancer Lett. , vol.75 , pp. 95-102
    • Vucenik, I.1    Sakamoto, K.2    Bansal, M.3    Shamsuddin, A.M.4
  • 21
    • 0005022930 scopus 로고
    • Antineoplastic action of inositol compounds
    • L. W. Wattenberg, M. Lipkin, and G. J. Kelloff (eds.), Boca Raton, FL: CRC Press, Inc.
    • Shamsuddin, A. M. and Sakamoto, K. Antineoplastic action of inositol compounds. In: L. W. Wattenberg, M. Lipkin, and G. J. Kelloff (eds.), Cancer Prevention, pp. 285-308. Boca Raton, FL: CRC Press, Inc., 1992.
    • (1992) Cancer Prevention , pp. 285-308
    • Shamsuddin, A.M.1    Sakamoto, K.2
  • 22
    • 0027493434 scopus 로고
    • Comparative cytotoxicities of selected minor dietary non-nutrients with chemopreventative properties
    • Babich, H., Borenfreund, L., and Stern, A. Comparative cytotoxicities of selected minor dietary non-nutrients with chemopreventative properties. Cancer Lett., 73: 127-133, 1993.
    • (1993) Cancer Lett. , vol.73 , pp. 127-133
    • Babich, H.1    Borenfreund, L.2    Stern, A.3
  • 23
    • 0026072276 scopus 로고
    • Modifying effects of the naturally occurring antioxidants γ-oryzanol, phytic acid, tannic acid and n-tritriacontane-16, 18-dione in a rat wide-spectrum organ carcinogenesis model
    • Lond.
    • Hirose, M., Ozaki, K., Takaba, K., Fukushima, S., Shirai, T., and Ito, M. Modifying effects of the naturally occurring antioxidants γ-oryzanol, phytic acid, tannic acid and n-tritriacontane-16, 18-dione in a rat wide-spectrum organ carcinogenesis model. Carcinogenesis (Lond.), 12: 1917-1921, 1991.
    • (1991) Carcinogenesis , vol.12 , pp. 1917-1921
    • Hirose, M.1    Ozaki, K.2    Takaba, K.3    Fukushima, S.4    Shirai, T.5    Ito, M.6
  • 24
    • 0006365064 scopus 로고
    • Colon carcinogenesis is inhibited more effectively by phytate than by selenium in F344 rats given 30 mg/kg azoxymethane
    • M. M. Jacobs (ed.), New York: Plenum Press
    • Pretlow, T. O., O'Riordan, M. A., and Pretlow, T. G. Colon carcinogenesis is inhibited more effectively by phytate than by selenium in F344 rats given 30 mg/kg azoxymethane. In: M. M. Jacobs (ed.), Diet and Cancer Markers, Prevention and Treatment, p. 244. New York: Plenum Press, 1994.
    • (1994) Diet and Cancer Markers, Prevention and Treatment , pp. 244
    • Pretlow, T.O.1    O'Riordan, M.A.2    Pretlow, T.G.3
  • 25
    • 0027452033 scopus 로고
    • Studies of chemopreventive effects of myo-inositol on benzo(a)pyrene-induced neoplasia of the lung and fore stomach of female A/J mice
    • Lond.
    • Estensen, R. D., and Wattenberg, L. W. Studies of chemopreventive effects of myo-inositol on benzo(a)pyrene-induced neoplasia of the lung and fore stomach of female A/J mice. Carcinogenesis (Lond.), 14: 1975-1977, 1993.
    • (1993) Carcinogenesis , vol.14 , pp. 1975-1977
    • Estensen, R.D.1    Wattenberg, L.W.2
  • 26
    • 0028909094 scopus 로고
    • Evaluation of chemo-preventative agents in different mechanistic classes using a rat tracheal epithelial cell culture transformation assay
    • Arnold, J. T., Wilkinson, B. P., Sharma, S., and Steele, V. E. Evaluation of chemo-preventative agents in different mechanistic classes using a rat tracheal epithelial cell culture transformation assay. Cancer Res., 55: 537-543, 1995.
    • (1995) Cancer Res. , vol.55 , pp. 537-543
    • Arnold, J.T.1    Wilkinson, B.P.2    Sharma, S.3    Steele, V.E.4
  • 27
    • 0029057655 scopus 로고    scopus 로고
    • Inositol hexaphosphate and inositol inhibit DMBA-induced rat mammary cancer
    • Lond.
    • Vucenik. I., Yang, G., and Shamsuddin, A. M. Inositol hexaphosphate and inositol inhibit DMBA-induced rat mammary cancer. Carcinogenesis (Lond.), 16: 1055-1058.
    • Carcinogenesis , vol.16 , pp. 1055-1058
    • Vucenik, I.1    Yang, G.2    Shamsuddin, A.M.3
  • 28
    • 0026658125 scopus 로고
    • Antitumor activity of phytic acid in murine transplanted and metastatic fibrosarcoma
    • Vucenik, I., Tomazic, V. J., Favbian, D., and Shamsuddin, A. M. Antitumor activity of phytic acid in murine transplanted and metastatic fibrosarcoma. Cancer Lett., 65: 9-13, 1992.
    • (1992) Cancer Lett. , vol.65 , pp. 9-13
    • Vucenik, I.1    Tomazic, V.J.2    Favbian, D.3    Shamsuddin, A.M.4
  • 31
    • 0031054518 scopus 로고    scopus 로고
    • Phosphatidylinositol-3 kinase is necessary for 12-O-tetradecanoylphorbol-13-acetate-induced cell transformation and AP-1 activation
    • Huang, H., Schmid, P. C., Ma, W-Y., Schmid, H. H. O., and Dong, Z. Phosphatidylinositol-3 kinase is necessary for 12-O-tetradecanoylphorbol-13-acetate-induced cell transformation and AP-1 activation. J. Biol. Chem., 272: 4187-4194, 1997.
    • (1997) J. Biol. Chem. , vol.272 , pp. 4187-4194
    • Huang, H.1    Schmid, P.C.2    Ma, W.-Y.3    Schmid, H.H.O.4    Dong, Z.5
  • 32
    • 0023665111 scopus 로고
    • Common elements in growth factor stimulation and oncogenic transformation: 85 kd phosphoprotein and phosphatidylinositol kinase activity
    • Kaplan, D. R., Whitman, M., Shaffhausen, B., Pallas, D. C., White, M., Cantley, L., and Roberts, T. M. Common elements in growth factor stimulation and oncogenic transformation: 85 kd phosphoprotein and phosphatidylinositol kinase activity. Cell, 50: 1021-1029, 1987.
    • (1987) Cell , vol.50 , pp. 1021-1029
    • Kaplan, D.R.1    Whitman, M.2    Shaffhausen, B.3    Pallas, D.C.4    White, M.5    Cantley, L.6    Roberts, T.M.7
  • 33
    • 0025027872 scopus 로고
    • Production of novel polyphosphoinositides in vivo is linked to cell transformation by polyomavirus middle T antigen
    • Serunian, L. A., Auger, K. R., Roberts, T., and Cantley, L. C. Production of novel polyphosphoinositides in vivo is linked to cell transformation by polyomavirus middle T antigen. J. Virol., 64: 4718-4725, 1989.
    • (1989) J. Virol. , vol.64 , pp. 4718-4725
    • Serunian, L.A.1    Auger, K.R.2    Roberts, T.3    Cantley, L.C.4
  • 34
    • 0024509946 scopus 로고
    • Role of phosphatidylinositol kinase in PDGF receptor signal transduction
    • Washington DC
    • Coughlin, S. R., Escobedo, J. A., and Williams, L. T. Role of phosphatidylinositol kinase in PDGF receptor signal transduction. Science (Washington DC), 243: 1191-1194, 1989.
    • (1989) Science , vol.243 , pp. 1191-1194
    • Coughlin, S.R.1    Escobedo, J.A.2    Williams, L.T.3
  • 35
    • 0028079661 scopus 로고
    • Blocking tumor promoter induced AP-1 activity inhibits induced transformation in JB6 cells
    • Dong, Z., Birrer, M. J., Watts, R. G., Matrisian, L. M., and Colburn, N. H. Blocking tumor promoter induced AP-1 activity inhibits induced transformation in JB6 cells. Proc. Natl. Acad. Sci. USA, 91: 609-613, 1994.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 609-613
    • Dong, Z.1    Birrer, M.J.2    Watts, R.G.3    Matrisian, L.M.4    Colburn, N.H.5
  • 36
    • 0028305998 scopus 로고
    • Comparison of AP-1 induction and transformation efficiency in anchorage dependent and independent conditions
    • Lond.
    • Dong, Z., Cmarik, J., Wendel, E. D., and Colburn, N. H. Comparison of AP-1 induction and transformation efficiency in anchorage dependent and independent conditions. Carcinogenesis (Lond.), 15: 1001-1004, 1994.
    • (1994) Carcinogenesis , vol.15 , pp. 1001-1004
    • Dong, Z.1    Cmarik, J.2    Wendel, E.D.3    Colburn, N.H.4
  • 37
    • 0029061281 scopus 로고
    • Progressive elevation of AP-1 activity during preneoplastic-to-neoplastic progression as modeled in mouse JB6 cell variants
    • Dong, Z., Watts, R. G., Sun, Y., and Colburn, N. H. Progressive elevation of AP-1 activity during preneoplastic-to-neoplastic progression as modeled in mouse JB6 cell variants. Int. J. Oncol., 7: 359-364, 1995.
    • (1995) Int. J. Oncol. , vol.7 , pp. 359-364
    • Dong, Z.1    Watts, R.G.2    Sun, Y.3    Colburn, N.H.4
  • 38
    • 0018682173 scopus 로고
    • Tumor promoter induces anchorage independence irreversibly
    • Colburn, N. H., Former, B. F., Nelson, K. A., and Yuspa, S. H. Tumor promoter induces anchorage independence irreversibly. Nature (Lond.), 281: 589-591, 1979.
    • (1979) Nature (Lond.) , vol.281 , pp. 589-591
    • Colburn, N.H.1    Former, B.F.2    Nelson, K.A.3    Yuspa, S.H.4
  • 39
    • 0024362088 scopus 로고
    • AP1/jun function is differentially induced in promotion-sensitive and resistant JB6 cells
    • Washington DC
    • Bernstein, L. R., and Colburn, N. H. AP1/jun function is differentially induced in promotion-sensitive and resistant JB6 cells. Science (Washington DC), 244: 566-569, 1989.
    • (1989) Science , vol.244 , pp. 566-569
    • Bernstein, L.R.1    Colburn, N.H.2
  • 40
    • 0030025874 scopus 로고    scopus 로고
    • Inhibition of tumor promoter-induced transformation by retinoids that transrepress AP-1 without transactivating retinoic acid response element
    • Li, J-J, Dong, Z., Dawson, M. I., and Colburn, N. H. Inhibition of tumor promoter-induced transformation by retinoids that transrepress AP-1 without transactivating retinoic acid response element. Cancer Res., 56: 483-489, 1996.
    • (1996) Cancer Res. , vol.56 , pp. 483-489
    • Li, J.-J.1    Dong, Z.2    Dawson, M.I.3    Colburn, N.H.4
  • 41
    • 0030027812 scopus 로고    scopus 로고
    • Inhibitory effects of ascorbic acid on AP-1 activity and transformation of JB6 cells
    • Huang, C., Ma, W., and Dong, Z. Inhibitory effects of ascorbic acid on AP-1 activity and transformation of JB6 cells. Int. J. Oncol., 8: 389-393, 1996.
    • (1996) Int. J. Oncol. , vol.8 , pp. 389-393
    • Huang, C.1    Ma, W.2    Dong, Z.3
  • 42
    • 0030951340 scopus 로고    scopus 로고
    • Blocking activator protein-1 activity, but not activating retinoic acid response clement, is required for the antitumor promotion effect of retinoic acid
    • Huang, C., Ma, W-Y., Dawson, M. I., Rincon, M., Flavell, R. A., and Dong, Z. Blocking activator protein-1 activity, but not activating retinoic acid response clement, is required for the antitumor promotion effect of retinoic acid. Proc. Natl. Acad. Sci. USA, 94: 5826-5830, 1997.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 5826-5830
    • Huang, C.1    Ma, W.-Y.2    Dawson, M.I.3    Rincon, M.4    Flavell, R.A.5    Dong, Z.6
  • 43
    • 0023769588 scopus 로고
    • The origins of human cancer: Molecular mechanisms of carcinogenesis and their implications for cancer prevention and treatment: Twenty-seventh G. H. A. Clowes Memorial Award lecture
    • Weinstein, I. B. The origins of human cancer: molecular mechanisms of carcinogenesis and their implications for cancer prevention and treatment: Twenty-seventh G. H. A. Clowes Memorial Award lecture. Cancer Res., 48: 4135-4143, 1988.
    • (1988) Cancer Res. , vol.48 , pp. 4135-4143
    • Weinstein, I.B.1
  • 44
    • 0025939947 scopus 로고
    • The role of the matrix methalloproteinase stromelysin in the progression of squamous cell carcinomas
    • Matrisian, L. M., McDonnell, S., Miller, D. B., Navre, M., Seftor, H. A., and Hendrix, M. J. C. The role of the matrix methalloproteinase stromelysin in the progression of squamous cell carcinomas. Am. J. Med. Sci., 302: 157-162, 1991.
    • (1991) Am. J. Med. Sci. , vol.302 , pp. 157-162
    • Matrisian, L.M.1    McDonnell, S.2    Miller, D.B.3    Navre, M.4    Seftor, H.A.5    Hendrix, M.J.C.6
  • 45
    • 0026060618 scopus 로고
    • The transactivating domain of the c-Jun proto-oncoprotein is required for cotransformation of rat embryo cells
    • Alani, R., Brown, P., Binetruy, B., Dosaker, H., Rosenberg, R. K., Angel, P., Karin, M., and Birrer, M. J. The transactivating domain of the c-Jun proto-oncoprotein is required for cotransformation of rat embryo cells. Mol. Cell. Biol., 11: 6286-6295, 1991.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 6286-6295
    • Alani, R.1    Brown, P.2    Binetruy, B.3    Dosaker, H.4    Rosenberg, R.K.5    Angel, P.6    Karin, M.7    Birrer, M.J.8
  • 46
    • 0027956852 scopus 로고
    • Stable expression of a c-Jun deletion mutant in two malignant mouse epidermal cell lines blocks tumor formation in nude mice
    • Domann, F. E., Levy, J. P., Birrer, M. J., and Bowden, G. T. Stable expression of a c-Jun deletion mutant in two malignant mouse epidermal cell lines blocks tumor formation in nude mice. Cell Growth & Differ., 5: 9-16, 1994.
    • (1994) Cell Growth & Differ. , vol.5 , pp. 9-16
    • Domann, F.E.1    Levy, J.P.2    Birrer, M.J.3    Bowden, G.T.4
  • 47
    • 0028989492 scopus 로고
    • c-Jun and multistage carcinogenesis: Association of overexpression of introduced c-jun with progression toward a neoplastic endpoint in mouse JB6 cells sensime to tumor promoter-induced transformation
    • Watts, R. G., Ben-Ari, H. T., Bernstein, L. R., Birrer, M. J., Winterstein, D., Wendel, E., and Colburn, N. H. c-Jun and multistage carcinogenesis: association of overexpression of introduced c-jun with progression toward a neoplastic endpoint in mouse JB6 cells sensime to tumor promoter-induced transformation. Mol. Carcinog., 13: 27-36, 1995.
    • (1995) Mol. Carcinog. , vol.13 , pp. 27-36
    • Watts, R.G.1    Ben-Ari, H.T.2    Bernstein, L.R.3    Birrer, M.J.4    Winterstein, D.5    Wendel, E.6    Colburn, N.H.7
  • 51
    • 0024601010 scopus 로고
    • PDGF-dependent tyrosine phosphorylation stimulates production of novel polyphosphoinositides in intact cells
    • Auger, K. R., Serunian, L. A., Soltoff, S. P., Libby, P., and Cantley, L., C. PDGF-dependent tyrosine phosphorylation stimulates production of novel polyphosphoinositides in intact cells. Cell, 57: 167-175, 1989.
    • (1989) Cell , vol.57 , pp. 167-175
    • Auger, K.R.1    Serunian, L.A.2    Soltoff, S.P.3    Libby, P.4    Cantley, L.C.5
  • 52
    • 0023897684 scopus 로고
    • Type I phosphatidylinositol kinase makes a novel inositol phospholipid, phosphatidylinositol-3-phosphate
    • Whitman, M., Downes, C. P., Keller, M., Keller, T., and Cantley, L. Type I phosphatidylinositol kinase makes a novel inositol phospholipid, phosphatidylinositol-3-phosphate. Nature (Lond.), 332: 644-646, 1988.
    • (1988) Nature (Lond.) , vol.332 , pp. 644-646
    • Whitman, M.1    Downes, C.P.2    Keller, M.3    Keller, T.4    Cantley, L.5


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