메뉴 건너뛰기




Volumn 323, Issue 1-2, 2003, Pages 115-123

A unifying model for functional difference and redundancy of presenilin-1 and -2 in cell apoptosis and differentiation

Author keywords

Alzheimer's disease; APP; Dominant negative; Notch; Processing; amyloid; Secretase

Indexed keywords

POLYCLONAL ANTIBODY; PRESENILIN 1; PRESENILIN 2; PROTEIN SUBUNIT;

EID: 0345059068     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.gene.2003.09.010     Document Type: Article
Times cited : (6)

References (29)
  • 2
    • 0027300294 scopus 로고
    • Expression of an extracellular deletion of Xotch diverts cell fate in Xenopus embryos
    • Coffman C.R., Skoglund P., Harris W.A., Kintner C.R. Expression of an extracellular deletion of Xotch diverts cell fate in Xenopus embryos. Cell. 73:1993;659-671.
    • (1993) Cell , vol.73 , pp. 659-671
    • Coffman, C.R.1    Skoglund, P.2    Harris, W.A.3    Kintner, C.R.4
  • 3
    • 0031405590 scopus 로고    scopus 로고
    • A developmental timer that regulates apoptosis at the onset of gastrulation
    • Hensey C., Gautier J. A developmental timer that regulates apoptosis at the onset of gastrulation. Mech. Dev. 69:1997;183-195.
    • (1997) Mech. Dev. , vol.69 , pp. 183-195
    • Hensey, C.1    Gautier, J.2
  • 4
    • 13044278313 scopus 로고    scopus 로고
    • Presenilin 2 deficiency causes a mild pulmonary phenotype and no changes in amyloid precursor protein processing but enhances the embryonic lethal phenotype of presenilin 1 deficiency
    • Herreman A.et al. Presenilin 2 deficiency causes a mild pulmonary phenotype and no changes in amyloid precursor protein processing but enhances the embryonic lethal phenotype of presenilin 1 deficiency. Proc. Natl. Acad. Sci. U. S. A. 96:1999;11872-11877.
    • (1999) Proc. Natl. Acad. Sci. U. S. A. , vol.96 , pp. 11872-11877
    • Herreman, A.1
  • 5
    • 0037444574 scopus 로고    scopus 로고
    • γ-Secretase activity requires the presenilin-dependent trafficking of nicastrin through the Golgi apparatus but not its complex glycosylation
    • Herreman A., Van Gassen G., Bentahir M., Nyabi O., Craessaerts K., Mueller U., Annaert W., De Strooper B. γ-Secretase activity requires the presenilin-dependent trafficking of nicastrin through the Golgi apparatus but not its complex glycosylation. J. Cell. Sci. 116:2003;1127-1136.
    • (2003) J. Cell. Sci. , vol.116 , pp. 1127-1136
    • Herreman, A.1    Van Gassen, G.2    Bentahir, M.3    Nyabi, O.4    Craessaerts, K.5    Mueller, U.6    Annaert, W.7    De Strooper, B.8
  • 6
    • 0034819230 scopus 로고    scopus 로고
    • Genetic algorithm-based maximum-likelihood analysis for molecular phylogeny
    • Katoh K., Kuma K., Miyata T. Genetic algorithm-based maximum-likelihood analysis for molecular phylogeny. J. Mol. Evol. 53:2001;477-484.
    • (2001) J. Mol. Evol. , vol.53 , pp. 477-484
    • Katoh, K.1    Kuma, K.2    Miyata, T.3
  • 7
    • 0347785491 scopus 로고    scopus 로고
    • Presenilin-dependent intramembrane proteolysis of CD44 leads to the liberation of its intracellular domain and the secretion of an Aβ-like peptide
    • Lammich S., Okochi M., Takeda M., Kaether C., Capell A., Zimmer A.K., Edbauer D., Walter J., Steiner H., Haass C. Presenilin-dependent intramembrane proteolysis of CD44 leads to the liberation of its intracellular domain and the secretion of an Aβ-like peptide. J. Biol. Chem. 277:2002;44754-44759.
    • (2002) J. Biol. Chem. , vol.277 , pp. 44754-44759
    • Lammich, S.1    Okochi, M.2    Takeda, M.3    Kaether, C.4    Capell, A.5    Zimmer, A.K.6    Edbauer, D.7    Walter, J.8    Steiner, H.9    Haass, C.10
  • 10
    • 0030671560 scopus 로고    scopus 로고
    • HOP-1, a Caenorhabditis elegans presenilin, appears to be functionally redundant with SEL-12 presenilin and to facilitate LIN-12 and GLP-1 signaling
    • Li X., Greenwald I. HOP-1, a Caenorhabditis elegans presenilin, appears to be functionally redundant with SEL-12 presenilin and to facilitate LIN-12 and GLP-1 signaling. Proc. Natl. Acad. Sci. U. S. A. 94:1997;12204-12209.
    • (1997) Proc. Natl. Acad. Sci. U. S. A. , vol.94 , pp. 12204-12209
    • Li, X.1    Greenwald, I.2
  • 11
    • 0032499750 scopus 로고    scopus 로고
    • Additional evidence for an eight-transmembrane-domain topology for Caenorhabditis elegans and human presenilins
    • Li X., Greenwald I. Additional evidence for an eight-transmembrane- domain topology for Caenorhabditis elegans and human presenilins. Proc. Natl. Acad. Sci. U. S. A. 95:1998;7109-7114.
    • (1998) Proc. Natl. Acad. Sci. U. S. A. , vol.95 , pp. 7109-7114
    • Li, X.1    Greenwald, I.2
  • 12
    • 0035965798 scopus 로고    scopus 로고
    • Characterization of the amphioxus presenilin gene in a high gene-density genomic region illustrates duplication during the vertebrate lineage
    • Martinez-Mir A., Canestro C., Gonzalez-Duarte R., Albalat R. Characterization of the amphioxus presenilin gene in a high gene-density genomic region illustrates duplication during the vertebrate lineage. Gene. 279:2001;157-164.
    • (2001) Gene , vol.279 , pp. 157-164
    • Martinez-Mir, A.1    Canestro, C.2    Gonzalez-Duarte, R.3    Albalat, R.4
  • 14
    • 0028019746 scopus 로고
    • Cell-free apoptosis in Xenopus egg extracts: Inhibition by Bcl-2 and requirement for an organelle fraction enriched in mitochondria
    • Newmeyer D.D., Farschon D.M., Reed J.C. Cell-free apoptosis in Xenopus egg extracts: inhibition by Bcl-2 and requirement for an organelle fraction enriched in mitochondria. Cell. 79:1994;353-364.
    • (1994) Cell , vol.79 , pp. 353-364
    • Newmeyer, D.D.1    Farschon, D.M.2    Reed, J.C.3
  • 15
    • 0029101491 scopus 로고
    • Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene
    • Rogaev E.I.et al. Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene. Nature. 376:1995;775-778.
    • (1995) Nature , vol.376 , pp. 775-778
    • Rogaev, E.I.1
  • 17
    • 0023375195 scopus 로고
    • The neighbor-joining method: A new method for reconstructing phylogenetic trees
    • Saitou N., Nei M. The neighbor-joining method: a new method for reconstructing phylogenetic trees. Mol. Biol. Evol. 4:1987;406-425.
    • (1987) Mol. Biol. Evol. , vol.4 , pp. 406-425
    • Saitou, N.1    Nei, M.2
  • 19
    • 0029004341 scopus 로고
    • Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease
    • Sherrington R.et al. Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease. Nature. 375:1995;754-760.
    • (1995) Nature , vol.375 , pp. 754-760
    • Sherrington, R.1
  • 20
    • 0034602957 scopus 로고    scopus 로고
    • Mutational analysis of intrinsic regions of presenilin 2 that determine its endoproteolytic cleavage and pathological function
    • Shirotani K., Takahashi K., Araki W., Maruyama K., Tabira T. Mutational analysis of intrinsic regions of presenilin 2 that determine its endoproteolytic cleavage and pathological function. J. Biol. Chem. 275:2000;3681-3686.
    • (2000) J. Biol. Chem. , vol.275 , pp. 3681-3686
    • Shirotani, K.1    Takahashi, K.2    Araki, W.3    Maruyama, K.4    Tabira, T.5
  • 21
    • 0031572282 scopus 로고    scopus 로고
    • Zygotic transcription is required to block a maternal program of apoptosis in Xenopus embryos
    • Sible J.C., Anderson J.A., Lewellyn A.L., Maller J.L. Zygotic transcription is required to block a maternal program of apoptosis in Xenopus embryos. Dev. Biol. 189:1997;335-346.
    • (1997) Dev. Biol. , vol.189 , pp. 335-346
    • Sible, J.C.1    Anderson, J.A.2    Lewellyn, A.L.3    Maller, J.L.4
  • 22
    • 0033214070 scopus 로고    scopus 로고
    • A loss of function mutation of presenilin-2 interferes with amyloid β-peptide production and notch signaling
    • Steiner H.et al. A loss of function mutation of presenilin-2 interferes with amyloid β-peptide production and notch signaling. J. Biol. Chem. 274:1999;28669-28673.
    • (1999) J. Biol. Chem. , vol.274 , pp. 28669-28673
    • Steiner, H.1
  • 23
    • 0031566256 scopus 로고    scopus 로고
    • Cloning of Xenopus presenilin-α and -β CDNAs and their differential expression in oogenesis and embryogenesis
    • Tsujimura A., Yasojima K., Hashimoto-Gotoh T. Cloning of Xenopus presenilin-α and -β cDNAs and their differential expression in oogenesis and embryogenesis. Biochem. Biophys. Res. Commun. 231:1997;392-396.
    • (1997) Biochem. Biophys. Res. Commun. , vol.231 , pp. 392-396
    • Tsujimura, A.1    Yasojima, K.2    Hashimoto-Gotoh, T.3
  • 24
    • 0029856850 scopus 로고    scopus 로고
    • Requirement of the familial Alzheimer's disease gene PS2 for apoptosis. Opposing effect of ALG-3
    • Vito P., Wolozin B., Ganjei J.K., Iwasaki K., Lacana E., D'Adamio L. Requirement of the familial Alzheimer's disease gene PS2 for apoptosis. Opposing effect of ALG-3. J. Biol. Chem. 271:1996;31025-31028.
    • (1996) J. Biol. Chem. , vol.271 , pp. 31025-31028
    • Vito, P.1    Wolozin, B.2    Ganjei, J.K.3    Iwasaki, K.4    Lacana, E.5    D'Adamio, L.6
  • 25
    • 0141760290 scopus 로고    scopus 로고
    • Differential expression of presenilins-α and -β (PSα and PSβ) in Xenopus laevis: Embryonic phosphorylations on PSα
    • Watanabe Y., Tsujimura A., Tabira T., Hashimoto-Gotoh Y. Differential expression of presenilins-α and -β (PSα and PSβ) in Xenopus laevis: embryonic phosphorylations on PSα Gene. 314:2003;165-172.
    • (2003) Gene , vol.314 , pp. 165-172
    • Watanabe, Y.1    Tsujimura, A.2    Tabira, T.3    Hashimoto-Gotoh, Y.4
  • 26
    • 0033535553 scopus 로고    scopus 로고
    • Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and γ-secretase activity
    • Wolfe M.S., Xia W., Ostaszewski B.L., Diehl T.S., Kimberly W.T., Selkoe D.J. Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and γ-secretase activity. Nature. 398:1999;513-517.
    • (1999) Nature , vol.398 , pp. 513-517
    • Wolfe, M.S.1    Xia, W.2    Ostaszewski, B.L.3    Diehl, T.S.4    Kimberly, W.T.5    Selkoe, D.J.6
  • 29
    • 0028064845 scopus 로고
    • Maximum likelihood phylogenetic estimation from DNA sequences with variable rates over sites: Approximate methods
    • Yang Z. Maximum likelihood phylogenetic estimation from DNA sequences with variable rates over sites: approximate methods. J. Mol. Evol. 39:1994;306-314.
    • (1994) J. Mol. Evol. , vol.39 , pp. 306-314
    • Yang, Z.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.