p53 induction and activation of DDR1 kinase counteract p53-mediated apoptosis and influence p53 regulation through a positive feedback loop

EMBO Journal

Volumn 22, Issue 6, 2003, Pages 1289-1301

  Ongusaha, Pat P ^a   Kim, Jong il ^e   Fang, Li ^b   Wong, Tai W ^c   Yancopoulos, George D ^d   Aaronson, Stuart A ^b   Lee, Sam W ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^c BRISTOL MYERS SQUIBB PHARMACEUTICAL RESEARCH INSTITUTE   (United States)

^d REGENERON PHARMACEUTICALS INC   (United States)

^e Hallym University   (South Korea)

Author keywords

Apoptosis; Cell survival; DDR1; MAPK; P53; Raf; Ras

Indexed keywords

DISCOIDIN; PHOSPHOTRANSFERASE; PROTEIN P53; RAF PROTEIN; RAS PROTEIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CELL SURVIVAL; DNA DAMAGE; ENZYME ACTIVATION; ENZYME INDUCTION; FEEDBACK SYSTEM; GENOTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FAMILY; TARGET CELL; TRANSCRIPTION REGULATION;

ADENOVIRIDAE; APOPTOSIS; CELL LINE; CELL SURVIVAL; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, RADIATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; GREEN FLUORESCENT PROTEINS; HELA CELLS; HUMANS; LUMINESCENT PROTEINS; MITOGEN-ACTIVATED PROTEIN KINASES; MODELS, BIOLOGICAL; MUTAGENS; PHOSPHORYLATION; RADIATION, IONIZING; RECEPTOR PROTEIN-TYROSINE KINASES; RNA, MESSENGER; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P53;

ANIMALIA;

EID: 0344837350     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/cdg129     Document Type: Article

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