Combined ETA/ETB receptor blockade of human peritoneal mesothelial cells inhibits collagen I RNA synthesis

Kidney International

Volumn 64, Issue 6, 2003, Pages 2033-2040

  Morgera, Stanislao ^a   Schlenstedt, Juliane ^b   Hambach, Pia ^b   Giessing, Markus ^b   Deger, Serdar ^b   Hocher, Berthold ^b   Neumayer, Hans Hellmut ^b  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b NONE

Author keywords

Endothelin; Endothelin receptor antagonist; Osmolarity; Peritoneal dialysis; Peritoneal fibrosis; Physical forces

Indexed keywords

3 [2 (3,4 DIMETHOXYPHENYL)ETHOXY] 2 (4,6 DIMETHOXY 2 PYRIMIDINYLOXY) 3,3 DIPHENYLPROPIONIC ACID; COLLAGEN TYPE 1; ENDOTHELIN RECEPTOR ANTAGONIST; GLUCOSE; GLYCEROL; RNA;

ARTICLE; CELL ACTIVITY; CELL CULTURE; CELL GROWTH; CONTROLLED STUDY; DRUG EFFECT; FORCE; HUMAN; HUMAN CELL; HUMAN TISSUE; LIQUID; MESOTHELIUM CELL; OSMOLARITY; PERITONEUM CELL; PHYSICAL STRESS; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN SECRETION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA SYNTHESIS; SHEAR STRESS; STATISTICAL SIGNIFICANCE;

EID: 0344514688     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1755.2003.00320.x     Document Type: Article

References (52)

1. PLUM J, HERMANN S, FUSSHOLLER A, et al: Peritoneal sclerosis in peritoneal dialysis patients related to dialysis settings and peritoneal transport properties. Kidney Int 59(Suppl 78): S42-S47, 2001
2. LEE HB, CHUNG SH, CHU WS, et al: Peritoneal dialysis in diabetic patients. Am J Kidney Dis 38(4 Suppl 1):S200-S203, 2001
3. LEE SK, KIM BS, YANG WS, et al: High glucose induces MCP-1 expression partly via tyrosine kinase-AP-1 pathway in peritoneal mesothelial cells. Kidney Int 60:55-64, 2001
4. JORRES A, BENDER TO, WITOWSKI J: Glucose degradation products and the peritoneal mesothelium. Perit Dial Int 20(Suppl 5):S19-S22, 2000
5. OGATA S, YORIOKA N, KOHNO N: Glucose and prednisolone alter basic fibroblast growth factor expression in peritoneal mesothelial cells and fibroblasts. J Am Soc Nephrol 12: 2787-2796, 2001
6. HUNG KY, CHEN CT, HUANG JW, et al: Dipyridamole inhibits TGF-beta-induced collagen gene expression in human peritoneal mesothelial cells. Kidney Int 60:1249-1257, 2001
7. CRONAUER MV, STADLMANN S, KLOCKER H, et al: Basic fibroblast growth factor synthesis by human peritoneal mesothelial cells: Induction by interleukin-1. Am J Pathol 155:1977-1984, 1999
8. WITOWSKI, WISNIEWSKA J, KORYBALSKA K, et al: Prolonged exposure to glucose degradation products impairs viability and function of human peritoneal mesothelial cells. J Am Soc Nephrol 12:2434-2441, 2001
9. KUMANO K, SCHILLER B, HJELLE JT, MORAN J: Effects of osmotic solutes on fibronectin mRNA expression in rat peritoneal mesothelial cells. Blood Purif 14:165-169, 1996
10. DAVIES PF, BARBEE KA, VOLIN MV, et al: Spatial relationships in early signaling events of flow-mediated endothelial mechanotransduction. Annu Rev Physiol 59:527-549, 1997
11. RESNICK N, GIMBRONE MA JR: Hemodynamic forces are complex regulators of endothelial gene expression. FASEB J 9:874-882, 1995
12. OSOL G: Mechanotransduction by vascular smooth muscle. J Vasc Res 32:275-292, 1995
13. SADOSHIMA J, IZUMO S: The cellular and molecular response of car diac myocytes to mechanical stress. Annu Rev Physiol 59:551-571, 1997
14. LIU M, POST M: Invited review: Mechanochemical signal transduction in the fetal lung. J Appl Physiol 89:2078-2084, 2000
15. MORGERA S, KUCHINKE S, BUDDE K, et al: Volume stress-induced peritoneal endothelin-1 release in continuous ambulatory peritoneal dialysis. J Am Soc Nephrol 10:2585-2590, 1999
16. HOCHER B, THÖNE-REINEKE C, ROHMEISS P, et al: Endothelin-1 transgenic mice develop renal cysts, interstitial fibrosis and glomerulosclerosis but not hypertension. J Clin Invest 99:1380-1389, 1997
17. RIZVI MAD, KATWA L, SPADONE DP, MYERS PR: The effects of endothelin-1 on collagen type I and type II synthesis in cultured porcine coronary artery vascular smooth muscle cells. J Mol Cell Cardiol 28:243-253, 1996
18. WIRTZ HR, DOBBS LG. Calcium mobilization and exocytosis after one mechanical stretch of lung epithelial cells. Science 250:1266-1269, 1990
19. HA H, YU MR, LEE HB: High glucose-induced PKC activation mediates TGF-beta 1 and fibronectin synthesis by peritoneal mesothelial cells. Kidney Int 59:463-470, 2001
20. WANG T, CHEN YG, YE RG, et al: Effect of glucose on TGF-beta 1 expression in peritoneal mesothelial cells. Adv Perit Dial 11:7-10, 1995
21. MEDCALF JF, WALLS J, PAWLUCZYK IZ, HARRIS KP: Effects of glucose dialysate on extracellular matrix production by human peritoneal mesothelial cells (HPMC): The role of TGF-beta. Nephrol Dial Transplant 16:1885-1892, 2001
22. MIYAUCHI T, MASAKI T: Pathophysiology of endothelin in the cardiovascular system. Annu Rev Physiol 61:391-415, 1999
23. GUARDA E, KATWA LC, MYERS PR, et al: Effects of endothelins on collagen turnover in cardiac fibroblasts. Cardiovasc Res 27:2130-2134, 1993
24. VANCHEESWARAN R, AZAM A, BLACK CM, DASHWOOD MR: Localisation of endothelin-1 and its binding sides in scleroderma skin. J Rheumatol 21:1268-1276, 1994
25. KNOCK GA, TERENGHI G, BUNKER CB, et al: Characterisation of endothelin-binding sites in human skin and their regulation in primary raynaud's phenomenon and systemic sclerosis. J Invest Dermatol 101:73-78, 1993
26. ABRAHAM DJ, VANCHEESWARAN R, DASHWOOD MR, et al: Increased levels of endothelin-1 and differential endothelin type A and B receptor expression in scleroderma associated fibrotic lung disease. Am J Pathol 151:831-841, 1997
27. ROCHEY DC, CHUNG JJ: Endothelin antagonism in experimental hepatic fibrosis. J Clin Invest 98:1381-1388, 1996
28. HOCHER B, LIEFELDT L, THÖNE-REINEKE C, et al: Characterization of the renal phenotype of transgenic rats expressing the human endothelin-2 gene. Hypertension 28:196-201, 1996
29. YAMAUCHI T, OHNAKA K, TAKAYANAGI R, et al: Enhanced secretion of endothelin-1 by elevated glucose levels from cultured bovine aortic endothelial cells. FEBS Lett 267:16-18, 1990
30. DENG DX, EVANS T, MUKHERJEE K, et al: Diabetes induced dysfunction in the retina: Role of endothelins. Diabetologia 42:1228-1234, 1999
31. HARGROVE GM, DUFRESNE J, WHITESIDE C, et al: Diabetes mellitus increases endothelin-1 gene transcription in rat kidney. Kidney Int 58:1534-1545, 2000
32. EVANS T, DENG DX, CHEN S, CHAKRABARTI S: Endothelin receptor blockade prevents augmented extracellular matrix component mRNA expression and capillary basement membrane thickening in the retina of diabetic and galactose-fed rats. Diabetes 49:662-666, 2000
33. HOCHER B, SCHWARZ A, REINBACHER D, et al: Effects of endothelin receptor antagonists on the progression of diabetic nephropathy. Nephron 81:161-169, 2001
34. CHEN S, KHAN ZA, CUKIERNIK M, CHAKRABARTI S: Differential activation of NF-κB and AP-1 in mediating endothelin dependent increased fibronectin synthesis in target organs of diabetic complications. Am J Physiol Endocrinol Metab 284:E1089-E1097, 2003
35. DOBBIE JW, LLOYD JK, GALL CA: Categorization of ultrastructural changes in peritoneal mesothelium, stroma and blood vessels in uremia and CAPD patients. Adv Perit Dial 6:3-12, 1990
36. MATEIJSEN MA, VAN DER WAL AC, HENDRIKS PM, et al: Vascular and interstitial changes in the peritoneum of CAPD patients with peritoneal sclerosis. Perit Dial Int 19:517-525, 1999
37. DI PAOLO N, SACCHI G: Peritoneal Vascular changes in continuous ambulatory peritoneal dialysis (CAPD): An in vivo model for the study of diabetic microangiopathy. Perit Dial Int 9:41-45, 1989
38. KOYA D, KING GL: Protein kinase C activation and the development of diabetic complications. Diabetes 47:859-866, 1998
39. KOYA D, JIROUSEK MR, LIN YW, et al: Characterization of protein kinase C beta isoform activation on the gene expression of transforming growth factor-beta, extracellular matrix components, and prostanoids in the glomeruli of diabetic rats. J Clin Invest 100:115-126, 1997
40. KOYA D, KING GL: Protein kinase C activation and the development of diabetic complications. Diabetes 47:859-866, 1998
41. CHEN S, MUKHERJEE S, CHAKRABORTY C, CHAKRABARTI S: High glucose induced, endothelin dependent, extracellular matrix protein synthesis is mediated via nuclear factor-kappa B and activating protein-1. Am J Physiol Cell Physiol 284:C263-C272, 2003
42. DOUMA CE, DE WAART DR, STRUIJK DG, KREDIET RT: The nitric oxide donor nitroprusside intraperitoneally affects peritoneal permeability in CAPD. Kidney Int 57:1885-1892, 1997
43. CHEN S, APOSTOLOVA MD, CHERIAN MG, CHAKRABARTI S: Interaction of endothelin-1 with vasoactive factors in mediating glucose-induced increased permeability in endothelial cells. Lab Invest 80:1311-1321, 2000
44. SCHILLING WP, MO M, ESKIN SG: Effect of shear stress on cytosolic Ca2+ of calf pulmonary artery endothelial cells. Exp Cell Res 198:31-35, 1992
45. BIALECKI RA, KULIK TJ, COLUCCI WS: Stretching increases calcium influx and efflux in cultured pulmonary arterial smooth muscle cells. Am J Physiol 263:L602-L606, 1992
46. BOITANO S, WOODRUFF ML, DIRKSEN ER: Evidence for voltage-sensitive, calcium-conducting channels in airway epithelial cells. Am J Physiol 269:C1547-C1556, 1995
47. SUKHAREV SI, BLOUNT P, MARTINAC B, et al: A large-conductance mechanosensitive channel in E. coli encoded by mscL alone. Nature 368:265-268, 1994.
48. PARK JB, SCHIFFRIN EL: Cardiac and vascular fibrosis and hypertrophy in aldosterone-infused rats: Role of endothelin-1. Am J Hypertens 15:164-169, 2002
49. BOFFA JJ, THARAUX PL, DUSSAULE JC, CHATZIANTONIOU C: Regression of renal vascular fibrosis by endothelin receptor antagonism. Hypertension 37:490-499, 2001
50. TOSTES RC, TOUYZ RM, HE G, et al: Endothelin a receptor blockade decreases expression of growth factors and collagen and improves matrix metalloproteinase-2 activity in kidneys from stroke-prone spontaneously hypertensive rats. J Cardiovasc Pharmacol 39:892-900, 2002
51. CHO JJ, HOCHER B, HERBST H, et al: An oral endothelin-A receptor antagonist blocks collagen synthesis and deposition in advanced rat liver fibrosis. Gastroenterology 118:1169-1178, 2000
52. RUBIN LJ, BADESCH DB, BARST RJ, et al: Bosentan therapy for pulmonary arterial hypertension. N Engl J Med 346:896-903, 2002