Independent Exponential Feeding of Glycerol and Methanol for Fed-Batch Culture of Recombinant Hansenula polymorpha DL-1

Applied Biochemistry and Biotechnology - Part A Enzyme Engineering and Biotechnology

Volumn 111, Issue 2, 2003, Pages 65-79

  Moon, H ^a   Kim, S W ^a   Lee, J ^a   Rhee, S K ^b   Choi, E S ^b   Kang, H A ^b   Kim, I H ^a   Hong, S I ^a  

^a Korea University   (South Korea)

^b Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

Author keywords

Exponential feeding; Fed batch culture; Hansenula polymorpha; Human epidermal growth factor; Mixed feed

Indexed keywords

EPIDERMAL GROWTH FACTOR; GLYCEROL; METHANOL;

ARTICLE; CONTROLLED STUDY; ENZYME SUBSTRATE; FED BATCH CULTURE; FUNGAL CELL; FUNGUS GROWTH; GENETIC RECOMBINATION; HANSENULA POLYMORPHA; KINETICS; NONHUMAN; PROTEIN SYNTHESIS; VOLUMETRY;

ALCOHOL OXIDOREDUCTASES; BIOREACTORS; CULTURE MEDIA; EPIDERMAL GROWTH FACTOR; FERMENTATION; GLYCEROL; HUMANS; METHANOL; PICHIA; PROMOTER REGIONS (GENETICS); RECOMBINANT PROTEINS; TRANSFORMATION, GENETIC;

FUNGI; PICHIA; PICHIA ANGUSTA;

EID: 0344011063     PISSN: 02732289     EISSN: None     Source Type: Journal    
DOI: 10.1385/ABAB:111:2:65     Document Type: Article

References (29)

1. Romanos, M. A., Scorer, C. A., and Clare, J. J. (1992), Yeast 8, 423-488.
2. Gellissen, G., Hollenberg, C. P., and Janowicz, Z. A. (1994), in Gene Expression in Recombinant Microorganisms, Smith, A., ed., Marcel Dekker, New York, pp. 195-239.
3. Faber, K. N., Harder, W., Greet, A. B., and Veenhuis, M. (1995), Yeast 11, 1084-1088.
4. Hollenberg, C. P. and Gellissen, G. (1997), Curr. Opin. Biotechnol. 6, 554-560.
5. Gellissen, G. (2000), Appl. Microbiol. Biotechnol. 54, 741-750.
6. Veale, R. A., Giuseppin, M. L. F., Vaneijk, H. M. J., Sudbery, P. E., and Verrips, C. T. (1992), Yeast 8, 361-372.
7. Zurek, C., Kubis, E., Keup, P., Horlein, D., Beunink, J., Thommes, J., Kula, M. R., Hollenberg, C. P., and Gellissen, G. (1996), Proc. Biochem. 31, 679-689.
8. Kim, C. H., Seo, H. W., Sohn, J. H., Choi, E. S., and Rhee, S. K. (1998), J. Ind. Microbiol. Biotechnol. 21, 1-5.
9. Brierley, R. A., Siegel, R. S., Bussineau, C. M., et al. (1990), US patent WO 9003431.
10. d'Anjou, M. C. and Daugulis, A. J. (2000), Biotechnol. Lett. 22, 341-346.
11. d'Anjou, M. C. and Daugulis, A. J. (2001), Biotechnol. Bioeng. 72, 1-11.
12. Files, D., Ogawa, M., Scaman, C. H., and Baldwin, S. A. (2001), Enzyme Microb. Technol. 29, 335-340.
13. Hellwig, S., Emde, F., Raven, N. P., Henke, M., Logt, P. V. D., and Fischer, R. (2001), Biotechnol. Bioeng. 74, 344-352.
14. Zhang, W., Bevins, M. A., Plantz B. A., Smith, L. A., and Meagher, M. M. (2000), Biotechnol. Bioeng. 70, 1-8.
15. Choi, E. S., Rhee, S. K., Sohn, J. H., Kang, H. A., and Bae, J. H. (1999), Korean patent pending, file no. 99-03095.
16. Rhee, S. K., Choi, E. S., Kim, C. H., Sohn, J. H., Kang, H. A., and Kim, H. Y. (1999), US patent 5,935,789.
17. Moon, H., Kim, H., Rhee, S. K., Choi, E. S., Kang, H. A., Kim, I. H., and Hong, S. I. (2002), Proc. Biochem. 38, 487-495.
18. Carpenter, G. and Cohen, S. (1979), Annu. Rev. Biochem. 48, 193-216.
19. Coppella, S. T. and Dhurjati, P. (1989), Biotechnol. Bioeng. 33, 976-983.
20. Ebisu, S., Takagi, H., Kodowaki, K., Yamagata, H., and Udaka, S. (1996), Ann. NY Acad. Sci. 782, 115-122.
21. Hamsa, P. V., Kachroo, P., and Chattoo, B. B. (1998), Curr. Genet. 33, 231-237.
22. Sivakesava, S., Xu, Z. N., Chen, Y. H., Hachett, J., Huang, R. C., Lam, E., and Lam, T. L. (1999), Proc. Biochem. 34, 893-900.
23. Voller, A., Bidwell, D. E., and Bartlet, A. (1979), in A Guide with Abstracts of Microplate Application, Dynatech Laboratories, Inc., pp. 10-43.
24. Modak, J. M., Lim, H. C., and Tayeb, Y. J. (1986), Biotechnol. Bioeng. 28, 1396-1407.
25. Yee, L. and Blanch, H. W. (1992), Bio/Technology 10, 1550-1557.
26. Egli, T., Bosshard, C., and Hamer, G. (1986), Biotechnol. Bioeng. 28, 1735-1741.
27. Curvers, S. P., Brixius, T., Klauser, J., Thommes, D., Weuster-Botz, R., Takors, and Wandrey, C. (2001), Biotechnol. Prog. 17, 495-502.
28. Yamane, T. and Shimizu, S. (1984), Adv. Biochem. Eng. 30, 147-194.
29. Kang, H. A., Kang, W., Hong, W. K., Kim, M. W., Kim, J. Y., Sohn, J. H., Choi, E. S., Choe, K. B., and Rhee, S. K. (2001), Biotechnol. Bioeng. 76, 175-185.