Production of recombinant hirudin in Hansenula polymorpha: Variation of gene expression level depends on methanol oxidase and fermentation strategies

Journal of Industrial Microbiology and Biotechnology

Volumn 21, Issue 1-2, 1998, Pages 1-5

  Kim, C H ^a   Seo, H W ^a   Kim, H Y ^a   Sohn, J H ^a   Choi, E S ^a   Rhee, S K ^a  

^a Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

Author keywords

Autonomously replicating sequence; Hansenula polymorpha; Hirudin; Methanol oxidase; Methylotrophic yeast

Indexed keywords

ANTICOAGULANT AGENT; ANTIOXIDANT; HIRUDIN; LEPIRUDIN; METHANOL; OXIDOREDUCTASE; TOCOPHEROL;

ARTICLE; EXPRESSION VECTOR; FERMENTATION; GENETIC VARIABILITY; HANSENULA POLYMORPHA; NONHUMAN;

HANSENULA POLYMORPHA;

EID: 0031742470     PISSN: 13675435     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.jim.2900545     Document Type: Article

References (13)

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