Development of expression systems for the production of recombinant human serum albumin using the MOX promoter in Hansenula polymorpha DL-1

Biotechnology and Bioengineering

Volumn 76, Issue 2, 2001, Pages 175-185

  Kang, Hyun Ah ^a   Kang, Whankoo ^b   Hong, Won Kyuong ^a   Kim, Moo Woong ^c   Kim, Jeong Yoon ^c   Sohn, Jung Hoon ^a   Choi, Eui Sung ^a   Choe, Keun Bum ^d   Rhee, Sang Ki ^a  

^a Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^b Hannam University   (South Korea)

^c Chungnam National University   (South Korea)

^d Dong Kook Pharmaceutical Co Ltd   (South Korea)

Author keywords

5 untranslated region; Copy number; Hansenula polymorpha; Human serum albumin; Methanol oxidase deficient phenotype; MOX promoter

Indexed keywords

DNA; FERMENTATION; GENES; METHANOL; YEAST;

POLYMORPHA EXPRESSION SYSTEMS;

BIOTECHNOLOGY;

ALBUMIN; METHANOL; OXIDOREDUCTASE; RECOMBINANT PROTEIN;

ARTICLE; BACTERIUM CULTURE; BACTERIUM TRANSFORMATION; BIOENGINEERING; CONTROLLED STUDY; FERMENTATION; GENE CASSETTE; GENE EXPRESSION; GENE LOCUS; HANSENULA POLYMORPHA; NONHUMAN; NORTHERN BLOTTING; PHENOTYPE; PRODUCTIVITY; PROMOTER REGION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

5' UNTRANSLATED REGIONS; ALCOHOL OXIDOREDUCTASES; BIOREACTORS; GENE DOSAGE; GENES, FUNGAL; GENETIC VECTORS; HUMANS; PICHIA; PLASMIDS; PROMOTER REGIONS (GENETICS); RECOMBINANT PROTEINS; RNA, MESSENGER; SERUM ALBUMIN; TRANSCRIPTION, GENETIC;

PICHIA ANGUSTA;

EID: 0034849969     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/bit.1157     Document Type: Article

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