메뉴 건너뛰기




Volumn 1, Issue 4, 1998, Pages 452-455

Small molecule inducers of neurotrophic function

Author keywords

[No Author keywords available]

Indexed keywords


EID: 0342979464     PISSN: 13697056     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (1)

References (37)
  • 1
    • 0028805849 scopus 로고
    • Nervous excitement over neurotrophic factors
    • Walsh G: Nervous excitement over neurotrophic factors. Biotechnology (1995) 13:1167-1171.
    • (1995) Biotechnology , vol.13 , pp. 1167-1171
    • Walsh, G.1
  • 2
    • 33749494383 scopus 로고    scopus 로고
    • New horizons in Alzheimer's disease therapy: Neurotrophin-like small molecules
    • Hudkins RL: New horizons in Alzheimer's disease therapy: Neurotrophin-like small molecules. Alzheimer's Disease ID Research Alert (1997) 2:407-416.
    • (1997) Alzheimer's Disease ID Research Alert , vol.2 , pp. 407-416
    • Hudkins, R.L.1
  • 6
    • 0028936727 scopus 로고
    • Evidence for nerve growth factor-poten-tiating activities of the nonpeptidic compound SR-57746A in PC12 cells
    • Pradines A, Magazin M, Schiltz P, Le Fur G, Caput D, Ferrara P: Evidence for nerve growth factor-poten-tiating activities of the nonpeptidic compound SR-57746A in PC12 cells. J Neurochem (1995) 64:1954-1964.
    • (1995) J Neurochem , vol.64 , pp. 1954-1964
    • Pradines, A.1    Magazin, M.2    Schiltz, P.3    Le Fur, G.4    Caput, D.5    Ferrara, P.6
  • 7
    • 0030061743 scopus 로고    scopus 로고
    • SR-57746A attenuates cytostatic drug-induced reduction of neurite outgrowth in co-cultures of rat dorsal root ganglia and Schwann cells
    • Ruift GSF, Makkink WK, Konings PNM: SR-57746A attenuates cytostatic drug-induced reduction of neurite outgrowth in co-cultures of rat dorsal root ganglia and Schwann cells. Neurosci Lett (1996) 203:9-12.
    • (1996) Neurosci Lett , vol.203 , pp. 9-12
    • Ruift, G.S.F.1    Makkink, W.K.2    Konings, P.N.M.3
  • 8
    • 0029023511 scopus 로고
    • Facilitating effects of SR-57746A on short-term memory in an operant delayed alternation task in aged rats
    • Roux S, Hubert I, Wettstein JG, Soubrié P, Le Fur G, Porsolt RD: Facilitating effects of SR-57746A on short-term memory in an operant delayed alternation task in aged rats. Drug Dev Res (1995) 35:83-93.
    • (1995) Drug Dev Res , vol.35 , pp. 83-93
    • Roux, S.1    Hubert, I.2    Wettstein, J.G.3    Soubrié, P.4    Le Fur, G.5    Porsolt, R.D.6
  • 10
    • 0030564998 scopus 로고    scopus 로고
    • Administration of amyloid β-peptides in the rat medial septum causes memory deficits: Reversal by SR-57746A, a non-peptide neurotrophic compound
    • Terranova JP, Kan JP, Storme JJ, Perreaut P, LeFur G, Soubrie P: Administration of amyloid β-peptides in the rat medial septum causes memory deficits: reversal by SR-57746A, a non-peptide neurotrophic compound. Neurosci Lett (1996) 213:79-82.
    • (1996) Neurosci Lett , vol.213 , pp. 79-82
    • Terranova, J.P.1    Kan, J.P.2    Storme, J.J.3    Perreaut, P.4    LeFur, G.5    Soubrie, P.6
  • 11
    • 0030670649 scopus 로고    scopus 로고
    • SR-57746A: An orally active non-peptide compound with neurotrophic and neuroprotective effects
    • Fournier J, Keane PE, Ferrara P, Soubrie P: SR-57746A: An orally active non-peptide compound with neurotrophic and neuroprotective effects. CNS Drug Rev (1997) 3:147-166.
    • (1997) CNS Drug Rev , vol.3 , pp. 147-166
    • Fournier, J.1    Keane, P.E.2    Ferrara, P.3    Soubrie, P.4
  • 12
    • 1842373335 scopus 로고    scopus 로고
    • AIT-082
    • AIT-082. Drugs Future (1997) 22:945-947.
    • (1997) Drugs Future , vol.22 , pp. 945-947
  • 13
    • 0028785192 scopus 로고
    • AIT-082, a unique purine derivative, enhances nerve growth factor mediated neurite outgrowth from PC12 cells
    • Middlemiss PJ, Glasky AJ, Rathbone MP, Werstuik E, Hindley S, Gysbers J: AIT-082, a unique purine derivative, enhances nerve growth factor mediated neurite outgrowth from PC12 cells. Neurosci Lett (1995) 199:131-134.
    • (1995) Neurosci Lett , vol.199 , pp. 131-134
    • Middlemiss, P.J.1    Glasky, A.J.2    Rathbone, M.P.3    Werstuik, E.4    Hindley, S.5    Gysbers, J.6
  • 16
    • 0029112805 scopus 로고
    • Protective effect of cyclosporin A on white matter changes in the rat brain after chronic hypoperfusion
    • Wakita H, Tomimoto H, Akiguchi I, Kimura J: Protective effect of cyclosporin A on white matter changes in the rat brain after chronic hypoperfusion. Stroke (1995) 26: 1415-1422.
    • (1995) Stroke , vol.26 , pp. 1415-1422
    • Wakita, H.1    Tomimoto, H.2    Akiguchi, I.3    Kimura, J.4
  • 17
    • 0029590050 scopus 로고
    • Cyclosporin A dramatically ameliorates CA1 hippocampal damage following transient forebrain ischaemia in the rat
    • Uchino H, Elmér E, Uchino K, Lindvall O, Siesjö BK: Cyclosporin A dramatically ameliorates CA1 hippocampal damage following transient forebrain ischaemia in the rat. Acta Physiol Scand (1995) 155: 469-471.
    • (1995) Acta Physiol Scand , vol.155 , pp. 469-471
    • Uchino, H.1    Elmér, E.2    Uchino, K.3    Lindvall, O.4    Siesjö, B.K.5
  • 18
    • 0028915760 scopus 로고
    • Cyclosporin A prevents ischemia-induced reduction of muscarinic acetylcholine receptors with suppression of microglial activation in gerbil hippocampus
    • Kondo Y, Ogawa N, Asanuma M, Nishibayashi S, Iwata E, Mori A: Cyclosporin A prevents ischemia-induced reduction of muscarinic acetylcholine receptors with suppression of microglial activation in gerbil hippocampus. Neurosci Res (1995) 22:123-127.
    • (1995) Neurosci Res , vol.22 , pp. 123-127
    • Kondo, Y.1    Ogawa, N.2    Asanuma, M.3    Nishibayashi, S.4    Iwata, E.5    Mori, A.6
  • 19
    • 0029099691 scopus 로고
    • Inhibition of blood-brain barrier disruption in experimental allergic encephalomyelitis by short-term therapy with dexamethasone or cyclosporin A
    • Paul C, Bolton C: Inhibition of blood-brain barrier disruption in experimental allergic encephalomyelitis by short-term therapy with dexamethasone or cyclosporin A. Int J Immunopharm (1995) 17:497-503.
    • (1995) Int J Immunopharm , vol.17 , pp. 497-503
    • Paul, C.1    Bolton, C.2
  • 20
    • 0027937489 scopus 로고
    • Immunophillins mediate the neuroprotective effects of FK-506 in focal ischemia
    • Sharkey J, Butcher SP: Immunophillins mediate the neuroprotective effects of FK-506 in focal ischemia. Nature (1994) 371:336-339.
    • (1994) Nature , vol.371 , pp. 336-339
    • Sharkey, J.1    Butcher, S.P.2
  • 21
    • 0030464736 scopus 로고    scopus 로고
    • Tacrolimus (FK-506) ameliorates skilled motor deficits produced by middle cerebral artery occlusion in rats
    • Sharkey J, Crawford JH, Butcher SP, Marston HM: Tacrolimus (FK-506) ameliorates skilled motor deficits produced by middle cerebral artery occlusion in rats. Stroke (1996) 27:2282-2286.
    • (1996) Stroke , vol.27 , pp. 2282-2286
    • Sharkey, J.1    Crawford, J.H.2    Butcher, S.P.3    Marston, H.M.4
  • 22
    • 0030019624 scopus 로고    scopus 로고
    • An immunosuppressant, FK-506, protects hippocampal neurons from forebrain ischemia in the Mongolian gerbil
    • Ide T, Morikawa E, Kirino T: An immunosuppressant, FK-506, protects hippocampal neurons from forebrain ischemia in the Mongolian gerbil. Neurosci Lett (1996) 204:157-160.
    • (1996) Neurosci Lett , vol.204 , pp. 157-160
    • Ide, T.1    Morikawa, E.2    Kirino, T.3
  • 23
    • 0030961442 scopus 로고    scopus 로고
    • Calclneurin inhibitor, FK-506, prevents reduction in the binding capacity of cyclic AMP-dependent protein kinase in ischemic gerbil brain
    • Tanaka K, Fukuuchi Y, Nozaki H, Nagata E, Kondo T, Koyama S, Dembo T: Calclneurin inhibitor, FK-506, prevents reduction in the binding capacity of cyclic AMP-dependent protein kinase in ischemic gerbil brain. J Cereb Blood Flow Metab (1997) 17:412-420.
    • (1997) J Cereb Blood Flow Metab , vol.17 , pp. 412-420
    • Tanaka, K.1    Fukuuchi, Y.2    Nozaki, H.3    Nagata, E.4    Kondo, T.5    Koyama, S.6    Dembo, T.7
  • 24
    • 0029918506 scopus 로고    scopus 로고
    • Neuroprotective effect of FK-506, an immunosuppressant, on transient global ischemia in gerbil
    • Tokime T, Nozaki K, Kikuchi H: Neuroprotective effect of FK-506, an immunosuppressant, on transient global ischemia in gerbil. Neurosci Lett (1996) 206:81-84.
    • (1996) Neurosci Lett , vol.206 , pp. 81-84
    • Tokime, T.1    Nozaki, K.2    Kikuchi, H.3
  • 25
    • 0027453536 scopus 로고
    • Immunosuppressant FK-506 enhances phosphorylation of nitric oxide synthase and protects against glutamate neurotoxicity
    • Dawson TM, Steiner JP, Dawson VL, Dinerman JL, Uhl GR, Snyder SH: Immunosuppressant FK-506 enhances phosphorylation of nitric oxide synthase and protects against glutamate neurotoxicity. Proc Natl Acad Sci USA (1993) 90:9808-9812.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 9808-9812
    • Dawson, T.M.1    Steiner, J.P.2    Dawson, V.L.3    Dinerman, J.L.4    Uhl, G.R.5    Snyder, S.H.6
  • 26
    • 0028352763 scopus 로고
    • The immunosuppressant FK-506 increases functional recovery and nerve regeneration following peripheral nerve injury
    • Gold BG, Storm-Dickerson T, Austin DR: The immunosuppressant FK-506 increases functional recovery and nerve regeneration following peripheral nerve injury. Rest Neurol Neurosci (1994) 6:287-296.
    • (1994) Rest Neurol Neurosci , vol.6 , pp. 287-296
    • Gold, B.G.1    Storm-Dickerson, T.2    Austin, D.R.3
  • 27
    • 0028783373 scopus 로고
    • The immunosuppressant FK-506 increases the rate of axonal regeneration in rat sciatic nerve
    • Gold BG, Katoh K, Storm-Dickerson T: The immunosuppressant FK-506 increases the rate of axonal regeneration in rat sciatic nerve. J Neurosci (1995) 15:7509-7516.
    • (1995) J Neurosci , vol.15 , pp. 7509-7516
    • Gold, B.G.1    Katoh, K.2    Storm-Dickerson, T.3
  • 28
    • 0030850505 scopus 로고    scopus 로고
    • Neuroprotective actions of FK-506 in experimental stroke: In vivo evidence against an antiexcitotoxic mechanism
    • Butcher SP, Henshall DC, Teramura Y, Iwasaki K, Sharkey J: Neuroprotective actions of FK-506 in experimental stroke: In vivo evidence against an antiexcitotoxic mechanism. J Neurosci (1997) 17:6939-6946.
    • (1997) J Neurosci , vol.17 , pp. 6939-6946
    • Butcher, S.P.1    Henshall, D.C.2    Teramura, Y.3    Iwasaki, K.4    Sharkey, J.5
  • 29
    • 0028956418 scopus 로고
    • Neuronal regeneration enhances the expression of the immunophilin FKBP-12
    • Lyons WE, Steiner JP, Snyder SH, Dawson TM: Neuronal regeneration enhances the expression of the immunophilin FKBP-12. J Neurosci (1995) 15:2985-2994.
    • (1995) J Neurosci , vol.15 , pp. 2985-2994
    • Lyons, W.E.1    Steiner, J.P.2    Snyder, S.H.3    Dawson, T.M.4
  • 30
    • 0031243290 scopus 로고    scopus 로고
    • Neural roles of immunophilins and their ligands
    • Sabatini DM, Lai MM, Snyder SH: Neural roles of immunophilins and their ligands. Mol Neurobiol (1997) 15:223-239.
    • (1997) Mol Neurobiol , vol.15 , pp. 223-239
    • Sabatini, D.M.1    Lai, M.M.2    Snyder, S.H.3
  • 31
    • 0030975605 scopus 로고    scopus 로고
    • Neurotrophic actions of nonimmunosuppressive analogues of immunosuppressive drugs FK-506, rapamycin and cyclosporin A
    • Steiner JP, Connolly MA, Valentine HI, Hamilton GS, Dawson TM, Hester L, Snyder SH: Neurotrophic actions of nonimmunosuppressive analogues of immunosuppressive drugs FK-506, rapamycin and cyclosporin A. Nat Med (1997) 3:421-428.
    • (1997) Nat Med , vol.3 , pp. 421-428
    • Steiner, J.P.1    Connolly, M.A.2    Valentine, H.I.3    Hamilton, G.S.4    Dawson, T.M.5    Hester, L.6    Snyder, S.H.7
  • 32
    • 0030839896 scopus 로고    scopus 로고
    • Comparative dose-dependence study of FK-506 and cyclosporin a on the rate of axonal regeneration in the rat sciatic nerve
    • Wang MS, Zeleny-Pooley M, Gold BG: Comparative dose-dependence study of FK-506 and cyclosporin a on the rate of axonal regeneration in the rat sciatic nerve. J Pharmacol Exp Ther (1997) 282:1084-1093.
    • (1997) J Pharmacol Exp Ther , vol.282 , pp. 1084-1093
    • Wang, M.S.1    Zeleny-Pooley, M.2    Gold, B.G.3
  • 33
    • 0026768730 scopus 로고
    • The immunosuppressive and toxic effects of FK-506 are mechanistically related: Pharmacology of a novel antagonist of FK-506 and rapamycin
    • Dumont FJ, Staruch MJ, Koprak SL: The immunosuppressive and toxic effects of FK-506 are mechanistically related: Pharmacology of a novel antagonist of FK-506 and rapamycin. J Exp Med (1992) 176:751-760.
    • (1992) J Exp Med , vol.176 , pp. 751-760
    • Dumont, F.J.1    Staruch, M.J.2    Koprak, S.L.3
  • 34
    • 0030591689 scopus 로고    scopus 로고
    • Preparation and in vitro activities of naphthyl and indolyl ether derivatives of the FK-506 related immunosuppressive macrolide ascomycin
    • Sinclair PJ, Wong F, Staruch MJ, Wiederrecht G, Parsons WH, Dumont F, Wyvratt M: Preparation and in vitro activities of naphthyl and indolyl ether derivatives of the FK-506 related immunosuppressive macrolide ascomycin. Bioorg Med Chem Lett (1996) 6:2193-2196.
    • (1996) Bioorg Med Chem Lett , vol.6 , pp. 2193-2196
    • Sinclair, P.J.1    Wong, F.2    Staruch, M.J.3    Wiederrecht, G.4    Parsons, W.H.5    Dumont, F.6    Wyvratt, M.7
  • 35
    • 0030762067 scopus 로고    scopus 로고
    • FKBP12-binding domain analogues of FK-506 are potent, nonimmunosuppressive neurotrophic agents in vitro and promote recovery in a mouse model of Parkinson's disease
    • Hamilton GS, Huang W, Connolly MA, Ross DT, Guo H, Valentine HL, Suzdak PD, Steiner JP: FKBP12-binding domain analogues of FK-506 are potent, nonimmunosuppressive neurotrophic agents in vitro and promote recovery in a mouse model of Parkinson's disease. Bioorg Med Chem Lett (1997) 7:1785-1790.
    • (1997) Bioorg Med Chem Lett , vol.7 , pp. 1785-1790
    • Hamilton, G.S.1    Huang, W.2    Connolly, M.A.3    Ross, D.T.4    Guo, H.5    Valentine, H.L.6    Suzdak, P.D.7    Steiner, J.P.8
  • 37
    • 0000045218 scopus 로고    scopus 로고
    • Neuroprotective and regenerative effects of immunophilin ligands in an animal model of Parkinson's disease
    • Costantini LC, Chaturvedi P, McCaffrey P, Deacon TW, Isacson O: Neuroprotective and regenerative effects of immunophilin ligands in an animal model of Parkinson's disease. Soc Neurosci Abst (1997) 27:P573.11.
    • (1997) Soc Neurosci Abst , vol.27
    • Costantini, L.C.1    Chaturvedi, P.2    McCaffrey, P.3    Deacon, T.W.4    Isacson, O.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.